JP4751387B2 - 分子表面相互作用を検出する方法 - Google Patents

分子表面相互作用を検出する方法 Download PDF

Info

Publication number
JP4751387B2
JP4751387B2 JP2007517999A JP2007517999A JP4751387B2 JP 4751387 B2 JP4751387 B2 JP 4751387B2 JP 2007517999 A JP2007517999 A JP 2007517999A JP 2007517999 A JP2007517999 A JP 2007517999A JP 4751387 B2 JP4751387 B2 JP 4751387B2
Authority
JP
Japan
Prior art keywords
analyte
sample
binding
medium
drug
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP2007517999A
Other languages
English (en)
Japanese (ja)
Other versions
JP2008503753A5 (https=
JP2008503753A (ja
Inventor
カール・アンダーション
アンナ・モーベルイ
Original Assignee
ジーイー・ヘルスケア・バイオ−サイエンシーズ・アーベー
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ジーイー・ヘルスケア・バイオ−サイエンシーズ・アーベー filed Critical ジーイー・ヘルスケア・バイオ−サイエンシーズ・アーベー
Priority claimed from PCT/SE2005/000933 external-priority patent/WO2006001749A1/en
Publication of JP2008503753A publication Critical patent/JP2008503753A/ja
Publication of JP2008503753A5 publication Critical patent/JP2008503753A5/ja
Application granted granted Critical
Publication of JP4751387B2 publication Critical patent/JP4751387B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Images

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54393—Improving reaction conditions or stability, e.g. by coating or irradiation of surface, by reduction of non-specific binding, by promotion of specific binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
JP2007517999A 2004-06-24 2005-06-17 分子表面相互作用を検出する方法 Expired - Fee Related JP4751387B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US58274304P 2004-06-24 2004-06-24
SE0401633-3 2004-06-24
US60/582,743 2004-06-24
SE0401633A SE0401633D0 (sv) 2004-06-24 2004-06-24 Method for detecting molecular surface interactions
PCT/SE2005/000933 WO2006001749A1 (en) 2004-06-24 2005-06-17 Method for detecting molecular surface interactions

Publications (3)

Publication Number Publication Date
JP2008503753A JP2008503753A (ja) 2008-02-07
JP2008503753A5 JP2008503753A5 (https=) 2008-07-03
JP4751387B2 true JP4751387B2 (ja) 2011-08-17

Family

ID=32906863

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2007517999A Expired - Fee Related JP4751387B2 (ja) 2004-06-24 2005-06-17 分子表面相互作用を検出する方法

Country Status (4)

Country Link
JP (1) JP4751387B2 (https=)
AT (1) ATE494553T1 (https=)
DE (1) DE602005025768D1 (https=)
SE (1) SE0401633D0 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102014115088A1 (de) * 2014-10-16 2016-04-21 Sovicell Gmbh Bestimmung von Bindungskonstanten mittels Gleichgewichtsverlagerung

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5753518A (en) * 1993-05-24 1998-05-19 Pharmacia Ab Method of determining affinity and kinetic properties
JP2002148188A (ja) * 2000-11-13 2002-05-22 Aisin Seiki Co Ltd ダニアレルゲン計測方法、ダニアレルゲン用の被検査物、及びダニアレルゲン計測装置
JP2002543394A (ja) * 1999-04-26 2002-12-17 サーロメッド・インコーポレーテッド 表現型および生物学上のマーカーの同定系
US6503701B1 (en) * 1999-06-15 2003-01-07 Biosensor Systems Design, Inc. Analytic sensor apparatus and method
WO2003081243A1 (en) * 2002-03-27 2003-10-02 Matsushita Electric Industrial Co., Ltd. Fluorescent polarization method, kit used therefor and biosensor
JP2004514114A (ja) * 2000-06-21 2004-05-13 バイオアレイ　ソルーションズ　リミテッド 特定のランダム粒子配列を適用した複数の被検体分子の分析方法
US6808938B2 (en) * 1999-06-18 2004-10-26 Biacore Ab Method and apparatus for assaying a drug candidate to estimate a pharmacokinetic parameter associated therewith

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5753518A (en) * 1993-05-24 1998-05-19 Pharmacia Ab Method of determining affinity and kinetic properties
JP2002543394A (ja) * 1999-04-26 2002-12-17 サーロメッド・インコーポレーテッド 表現型および生物学上のマーカーの同定系
US6503701B1 (en) * 1999-06-15 2003-01-07 Biosensor Systems Design, Inc. Analytic sensor apparatus and method
US6808938B2 (en) * 1999-06-18 2004-10-26 Biacore Ab Method and apparatus for assaying a drug candidate to estimate a pharmacokinetic parameter associated therewith
JP2004514114A (ja) * 2000-06-21 2004-05-13 バイオアレイ　ソルーションズ　リミテッド 特定のランダム粒子配列を適用した複数の被検体分子の分析方法
JP2002148188A (ja) * 2000-11-13 2002-05-22 Aisin Seiki Co Ltd ダニアレルゲン計測方法、ダニアレルゲン用の被検査物、及びダニアレルゲン計測装置
WO2003081243A1 (en) * 2002-03-27 2003-10-02 Matsushita Electric Industrial Co., Ltd. Fluorescent polarization method, kit used therefor and biosensor

Also Published As

Publication number Publication date
ATE494553T1 (de) 2011-01-15
SE0401633D0 (sv) 2004-06-24
JP2008503753A (ja) 2008-02-07
DE602005025768D1 (de) 2011-02-17

Similar Documents

Publication Publication Date Title
JP5855246B2 (ja) 校正不要分析による活性濃度の決定方法
US11796536B2 (en) Method for determining analyte-ligand binding on a sensor surface
CN102667448B (zh) 用于相互作用分析的方法和系统
EP1766398B1 (en) Method for detecting molecular surface interactions
CN102667447B (zh) 用于结合行为分析的方法和系统
US7320879B2 (en) Method of determining site-specificity and kit therefor
JP4495151B2 (ja) 相互作用の特性決定のための方法および装置
JP6540710B2 (ja) 速い解離速度の相互作用カイネティクスの決定方法
JP4751387B2 (ja) 分子表面相互作用を検出する方法
US20110152120A1 (en) method of characterizing antibodies
CN119804394B (zh) 一种基于金纳米海胆的复合结构光纤传感器及其在pd-l1检测中的应用
JP6662525B2 (ja) 光学センサ表面における物質移動特性の正規化
EP1579217B1 (en) Method of determining site-specificity and kit therefor
JP2006078209A (ja) 被験物質のスクリーニング方法
JP2006078211A (ja) 被験物質のスクリーニング方法

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20080515

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20080515

A711 Notification of change in applicant

Free format text: JAPANESE INTERMEDIATE CODE: A712

Effective date: 20080610

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20100716

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20100727

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20101015

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20101214

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20110310

A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20110426

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20110520

R150 Certificate of patent or registration of utility model

Free format text: JAPANESE INTERMEDIATE CODE: R150

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20140527

Year of fee payment: 3

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

LAPS Cancellation because of no payment of annual fees