JP4734245B2 - 外因性ポリペプチドを発現するヒト皮膚等価物 - Google Patents

外因性ポリペプチドを発現するヒト皮膚等価物 Download PDF

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JP4734245B2
JP4734245B2 JP2006522631A JP2006522631A JP4734245B2 JP 4734245 B2 JP4734245 B2 JP 4734245B2 JP 2006522631 A JP2006522631 A JP 2006522631A JP 2006522631 A JP2006522631 A JP 2006522631A JP 4734245 B2 JP4734245 B2 JP 4734245B2
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cells
niks
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JP2007520206A5 (enExample
JP2007520206A (ja
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ジョーン エム． センタニ
リン アレン−ホフマン
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ストラタテック コーポレーション
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    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/60—Materials for use in artificial skin
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/36—Skin; Hair; Nails; Sebaceous glands; Cerumen; Epidermis; Epithelial cells; Keratinocytes; Langerhans cells; Ectodermal cells
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    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
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    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
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    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
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    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3895—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells using specific culture conditions, e.g. stimulating differentiation of stem cells, pulsatile flow conditions
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    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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    • C12N5/0625—Epidermal cells, skin cells; Cells of the oral mucosa
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JP2006522631A 2003-08-01 2004-07-30 外因性ポリペプチドを発現するヒト皮膚等価物 Expired - Lifetime JP4734245B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US49186903P 2003-08-01 2003-08-01
US60/491,869 2003-08-01
US49366403P 2003-08-08 2003-08-08
US60/493,664 2003-08-08
PCT/US2004/024627 WO2005012492A2 (en) 2003-08-01 2004-07-30 Human skin equivalents expressing exogenous polypeptides

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JP2007520206A JP2007520206A (ja) 2007-07-26
JP2007520206A5 JP2007520206A5 (enExample) 2010-12-16
JP4734245B2 true JP4734245B2 (ja) 2011-07-27

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US (8) US7674291B2 (enExample)
EP (4) EP3473102A1 (enExample)
JP (1) JP4734245B2 (enExample)
AU (2) AU2004262002B2 (enExample)
CA (1) CA2534349C (enExample)
IL (1) IL173466A (enExample)
NZ (1) NZ545404A (enExample)
PT (1) PT3100611T (enExample)
WO (1) WO2005012492A2 (enExample)

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CA2483547C (en) * 2002-04-30 2012-03-20 Stratatech Corporation Keratinocytes expressing exogenous angiogenic growth factors
CA2534349C (en) 2003-08-01 2012-04-10 Stratatech Corporation Human skin equivalents expressing exogenous polypeptides
CA2600177C (en) * 2005-03-01 2011-06-14 Stratatech Corporation Human skin equivalents expressing exogenous polypeptides
EP2277899B1 (en) * 2006-04-27 2015-07-08 Singapore Health Services Pte Ltd Antimicrobial peptides
EP3375479B1 (en) 2007-05-18 2023-03-22 Boston Scientific Scimed, Inc. Medical drive systems
SI2514436T1 (en) * 2007-11-07 2018-04-30 Genentech, Inc. IL-22 for use in the treatment of microbial diseases
PT2215212T (pt) 2007-11-14 2017-12-01 Stratatech Corp Armazenamento a frio de equivalentes de pele cultivados de forma organotípica para aplicações clínicas
US9115180B2 (en) 2008-01-07 2015-08-25 Rapid Pathogen Screening, Inc. Use of peptides for promoting wound healing
ES2671143T3 (es) * 2008-01-07 2018-06-05 Rapid Pathogen Screening, Inc. Uso de péptidos para estimular la cicatrización de heridas
US8815177B2 (en) 2008-01-24 2014-08-26 Sandia Corporation Methods and devices for immobilization of single particles in a virtual channel in a hydrodynamic trap
EP2352472B1 (en) * 2008-11-04 2017-01-04 Stratatech Corporation Dried and irradiated skin equivalents for ready use
US20100330046A1 (en) * 2009-05-21 2010-12-30 Stratatech Corporation Human skin substitutes expressing il-12
DE102010004541A1 (de) * 2010-01-14 2011-07-21 Christian-Albrechts-Universität zu Kiel, 24118 Chimäre humane beta-Defensine
KR101329774B1 (ko) 2010-06-16 2013-11-15 주식회사 나이벡 항균 또는 항염증 활성을 가지는 펩타이드 및 이를 유효성분으로 함유하는 약제학적 조성물
US20130310326A1 (en) 2012-05-18 2013-11-21 Rapid Pathogen Screening, Inc. Histatin for Corneal Wound Healing and Ocular Surface Disease
PT2967836T (pt) * 2013-03-13 2019-01-21 Stratatech Corp Criopreservação de substitutos de pele humana viáveis
HK1218424A1 (zh) 2013-03-15 2017-02-17 F. Hoffmann-La Roche Ag Il-22多肽和il-22 fc融合蛋白及其使用方法
US9238090B1 (en) 2014-12-24 2016-01-19 Fettech, Llc Tissue-based compositions
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