JP4680894B2 - 安定化させた煙霧剤分散体 - Google Patents

安定化させた煙霧剤分散体 Download PDF

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Publication number
JP4680894B2
JP4680894B2 JP2006509816A JP2006509816A JP4680894B2 JP 4680894 B2 JP4680894 B2 JP 4680894B2 JP 2006509816 A JP2006509816 A JP 2006509816A JP 2006509816 A JP2006509816 A JP 2006509816A JP 4680894 B2 JP4680894 B2 JP 4680894B2
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JP
Japan
Prior art keywords
dispersion
nanoparticles
drug
continuous phase
propellant
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
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JP2006509816A
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English (en)
Japanese (ja)
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JP2006526624A (ja
JP2006526624A5 (https=
Inventor
アール．ジュニア バラン，ジミー
ジェイ． ガブリオ，ブライアン
エス． ステフェリー，ジェイムズ
ダブリュ． スタイン，スティーブン
イー． ウッド，トーマス
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3M Innovative Properties Co
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3M Innovative Properties Co
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Publication of JP2006526624A5 publication Critical patent/JP2006526624A5/ja
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/12—Aerosols; Foams
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/0095—Preparation of aerosols
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82B—NANOSTRUCTURES FORMED BY MANIPULATION OF INDIVIDUAL ATOMS, MOLECULES, OR LIMITED COLLECTIONS OF ATOMS OR MOLECULES AS DISCRETE UNITS; MANUFACTURE OR TREATMENT THEREOF
    • B82B1/00—Nanostructures formed by manipulation of individual atoms or molecules, or limited collections of atoms or molecules as discrete units
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K23/00—Use of substances as emulsifying, wetting, dispersing, or foam-producing agents
    • C09K23/017—Mixtures of compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K23/00—Use of substances as emulsifying, wetting, dispersing, or foam-producing agents
    • C09K23/38—Alcohols, e.g. oxidation products of paraffins

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Materials Engineering (AREA)
  • Pulmonology (AREA)
  • Otolaryngology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Nanotechnology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2006509816A 2003-05-30 2004-04-08 安定化させた煙霧剤分散体 Expired - Fee Related JP4680894B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/449,443 US7459146B2 (en) 2003-05-30 2003-05-30 Stabilized aerosol dispersions
PCT/US2004/010847 WO2004108118A1 (en) 2003-05-30 2004-04-08 Stabilized aerosol dispersions

Publications (3)

Publication Number Publication Date
JP2006526624A JP2006526624A (ja) 2006-11-24
JP2006526624A5 JP2006526624A5 (https=) 2007-05-24
JP4680894B2 true JP4680894B2 (ja) 2011-05-11

Family

ID=33451787

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2006509816A Expired - Fee Related JP4680894B2 (ja) 2003-05-30 2004-04-08 安定化させた煙霧剤分散体

Country Status (6)

Country Link
US (1) US7459146B2 (https=)
EP (1) EP1628645A1 (https=)
JP (1) JP4680894B2 (https=)
KR (1) KR20060038938A (https=)
CN (1) CN1798549B (https=)
WO (1) WO2004108118A1 (https=)

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US20040242729A1 (en) * 2003-05-30 2004-12-02 3M Innovative Properties Company Stabilized particle dispersions containing surface-modified inorganic nanoparticles
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US8367734B1 (en) 2005-08-11 2013-02-05 Amphastar Pharmaceuticals Inc. Stable epinephrine suspension formulation with high inhalation delivery efficiency
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US20070099883A1 (en) * 2005-10-07 2007-05-03 Cheryl Lynn Calis Anhydrous mometasone furoate formulation
US7767736B2 (en) * 2005-12-05 2010-08-03 3M Innovative Properties Company Flame retardant polymer composition
DE102006000691A1 (de) * 2006-01-02 2007-07-05 Henkel Kgaa Aerosol-Reiniger mit korrosionsinhibierender Wirkung
US20100119697A1 (en) * 2006-05-10 2010-05-13 3M Innovative Properties Company Compositions and coatings containing fluorescent, inorganic nanoparticles
CN101108166B (zh) * 2006-07-19 2011-07-27 鲁明华 定量纳米气雾剂及其制备方法
US20100062475A1 (en) * 2007-01-16 2010-03-11 Sumitomo Bakelite Company Particle for medical use, particle for anlaysis and method of producing the same
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WO2008131063A1 (en) * 2007-04-19 2008-10-30 3M Innovative Properties Company Methods of use of solid support material for binding biomolecules
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US8404876B2 (en) 2008-05-08 2013-03-26 3M Innovative Properties Company Process for producing nanoparticles
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US11337962B2 (en) 2009-09-25 2022-05-24 Upsher-Smith Laboratories, Llc Formulations comprising triptan compounds
CN102416179B (zh) 2010-09-28 2014-05-07 益得生物科技股份有限公司 用于哮喘的吸入性复方组合物
CN103328038A (zh) 2010-12-01 2013-09-25 史拜诺莫度雷森公司 向神经解剖结构直接递送药剂
EP3319907B1 (de) 2015-07-10 2020-08-05 Evonik Operations GmbH Sio2 enthaltende dispersion mit hoher salzstabilität
EP3319905A1 (de) 2015-07-10 2018-05-16 Evonik Degussa GmbH Metalloxid enthaltende dispersion mit hoher salzstabilität
US10723628B2 (en) 2015-07-10 2020-07-28 Evonik Operations Gmbh SiO2 containing dispersion with high salt stability
EP3368633B1 (en) 2015-10-26 2020-05-27 Evonik Operations GmbH Method of obtaining mineral oil using a silica fluid
JP2021531299A (ja) 2018-07-23 2021-11-18 トレビ セラピューティクス インコーポレイテッド 慢性咳嗽、息切れ、及び呼吸困難の治療
KR20220127849A (ko) 2020-01-10 2022-09-20 트레비 테라퓨틱스, 인코포레이티드 날부핀의 투여 방법
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Also Published As

Publication number Publication date
US7459146B2 (en) 2008-12-02
JP2006526624A (ja) 2006-11-24
CN1798549B (zh) 2011-03-09
WO2004108118A1 (en) 2004-12-16
EP1628645A1 (en) 2006-03-01
KR20060038938A (ko) 2006-05-04
CN1798549A (zh) 2006-07-05
US20040241101A1 (en) 2004-12-02

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