JP4648001B2 - ムチン−免疫グロブリン融合タンパク質 - Google Patents

ムチン−免疫グロブリン融合タンパク質 Download PDF

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Publication number
JP4648001B2
JP4648001B2 JP2004527246A JP2004527246A JP4648001B2 JP 4648001 B2 JP4648001 B2 JP 4648001B2 JP 2004527246 A JP2004527246 A JP 2004527246A JP 2004527246 A JP2004527246 A JP 2004527246A JP 4648001 B2 JP4648001 B2 JP 4648001B2
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Prior art keywords
polypeptide
cell
mucin
cells
psgl
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JP2004527246A
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Japanese (ja)
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JP2005535699A5 (enExample
JP2005535699A (ja
Inventor
ヨン ホルガーソン，
ジニン リウ，
アンキ グスタフソン，
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レコファーマ アーベー
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4727—Mucins, e.g. human intestinal mucin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Transplantation (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
JP2004527246A 2002-08-09 2003-08-11 ムチン−免疫グロブリン融合タンパク質 Expired - Fee Related JP4648001B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US40221102P 2002-08-09 2002-08-09
PCT/IB2003/003881 WO2004015057A2 (en) 2002-08-09 2003-08-11 Mucin-immunoglobulin fusion proteins

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2010113707A Division JP2010235614A (ja) 2002-08-09 2010-05-17 ムチン−免疫グロブリン融合タンパク質

Publications (3)

Publication Number Publication Date
JP2005535699A JP2005535699A (ja) 2005-11-24
JP2005535699A5 JP2005535699A5 (enExample) 2006-11-09
JP4648001B2 true JP4648001B2 (ja) 2011-03-09

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Family Applications (2)

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JP2004527246A Expired - Fee Related JP4648001B2 (ja) 2002-08-09 2003-08-11 ムチン−免疫グロブリン融合タンパク質
JP2010113707A Withdrawn JP2010235614A (ja) 2002-08-09 2010-05-17 ムチン−免疫グロブリン融合タンパク質

Family Applications After (1)

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JP2010113707A Withdrawn JP2010235614A (ja) 2002-08-09 2010-05-17 ムチン−免疫グロブリン融合タンパク質

Country Status (7)

Country Link
US (1) US7638323B2 (enExample)
EP (1) EP1534748A2 (enExample)
JP (2) JP4648001B2 (enExample)
AU (1) AU2003263411B8 (enExample)
CA (1) CA2495743C (enExample)
NZ (1) NZ538629A (enExample)
WO (1) WO2004015057A2 (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003233008B2 (en) * 2002-04-22 2008-04-24 Recopharma Ab Fusion polypeptides and methods for inhibiting microbial adhesion
US8129506B2 (en) * 2003-10-24 2012-03-06 Genzyme Corporation Modulation of the interaction of MUC1 with MUC1 ligands
AU2007251256B2 (en) * 2006-01-26 2013-03-07 Recopharma Ab Compositions and methods for inhibiting viral adhesion
WO2009003621A1 (en) * 2007-06-29 2009-01-08 F. Hoffmann-La Roche Ag Cho cell
US20090280134A1 (en) * 2008-05-09 2009-11-12 Recopharma Ab Compositions and methods for inhibiting toxin a from clostridium difficile
CA2722127A1 (en) * 2008-05-09 2009-11-12 Recopharma Ab Compositions and methods for inhibiting shiga toxin and shiga-like toxin
JP2012503471A (ja) 2008-05-30 2012-02-09 グライコフィ， インコーポレイテッド 末端アルファ−１，３−結合ガラクトースを有するタンパク質の製造のための酵母株
EP2593467A4 (en) * 2010-07-14 2014-03-12 Vancouver Biotech Ltd ANTICANCER VACCINES AND ANTIBODY-BASED MEDICINES BASED ON GLUCIDIC HAPTENES
WO2012085165A1 (en) * 2010-12-21 2012-06-28 Recopharma Ab Tear substitutes
WO2013184938A2 (en) 2012-06-08 2013-12-12 Alkermes. Inc. Fusion polypeptides comprising mucin-domain polypeptide linkers
RU2528251C2 (ru) * 2012-12-07 2014-09-10 Общество с ограниченной ответственностью "Гематологическая Корпорация" (ООО "ГемаКор") СЛИТЫЙ БЕЛОК ТИОРЕДОКСИНА И ДОМЕНА 4 ИНФЕСТИНА, СПОСОБ ЕГО ПОЛУЧЕНИЯ, ЭКСПРЕССИОННАЯ ПЛАЗМИДНАЯ ДНК, КОДИРУЮЩАЯ СЛИТЫЙ БЕЛОК, И БАКТЕРИЯ РОДА Escherichia coli, ТРАНСФОРМИРОВАННАЯ ТАКОЙ ПЛАЗМИДНОЙ ДНК
SI4065585T1 (sl) 2019-11-25 2025-11-28 Alkermes, Inc. Substituirane makrociklične spojine ter z njimi povezani postopki zdravljenja
US11760747B2 (en) 2020-12-21 2023-09-19 Alkermes, Inc. Substituted piperidino compounds and related methods of treatment
WO2024158939A1 (en) * 2023-01-25 2024-08-02 Sanford Burnham Prebys Medical Discovery Institute Psgl1 antagonists and uses thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5225538A (en) * 1989-02-23 1993-07-06 Genentech, Inc. Lymphocyte homing receptor/immunoglobulin fusion proteins
US6136310A (en) * 1991-07-25 2000-10-24 Idec Pharmaceuticals Corporation Recombinant anti-CD4 antibodies for human therapy
US5516964A (en) * 1994-01-21 1996-05-14 Sun Company, Inc. (R&M) Hydrocarbon isomerization using solid superacid catalysts comprising platinum metal
SE9701127D0 (sv) * 1997-03-26 1997-03-26 Karolinska Innovations Ab Antigenic fusionprotein carrying GALal, 3GAL epitopes

Also Published As

Publication number Publication date
CA2495743A1 (en) 2004-02-19
WO2004015057A9 (en) 2004-07-29
US20040137580A1 (en) 2004-07-15
US7638323B2 (en) 2009-12-29
AU2003263411B8 (en) 2011-04-14
JP2010235614A (ja) 2010-10-21
JP2005535699A (ja) 2005-11-24
AU2003263411B2 (en) 2010-12-16
NZ538629A (en) 2008-05-30
WO2004015057A3 (en) 2005-01-20
CA2495743C (en) 2011-01-25
WO2004015057A2 (en) 2004-02-19
EP1534748A2 (en) 2005-06-01
AU2003263411A1 (en) 2004-02-25

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