JP4625180B2 - 被分析物の蛍光ランタニドキレートによる検出 - Google Patents

被分析物の蛍光ランタニドキレートによる検出 Download PDF

Info

Publication number
JP4625180B2
JP4625180B2 JP2000535930A JP2000535930A JP4625180B2 JP 4625180 B2 JP4625180 B2 JP 4625180B2 JP 2000535930 A JP2000535930 A JP 2000535930A JP 2000535930 A JP2000535930 A JP 2000535930A JP 4625180 B2 JP4625180 B2 JP 4625180B2
Authority
JP
Japan
Prior art keywords
lanthanide metal
glucose
chelator
chelate complex
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP2000535930A
Other languages
English (en)
Japanese (ja)
Other versions
JP2002506973A5 (enExample
JP2002506973A (ja
Inventor
エドウィン・エフ・ウルマン
アレクサンドレ・ブイ・ニコライチック
ジョージ・ワイ・ダニロフ
デイビッド・パーカー
アーサー・イー・コルビン
アリストル・ジー・カリブレテノス
Original Assignee
センサーズ・フォー・メディシン・アンド・サイエンス・インコーポレイテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by センサーズ・フォー・メディシン・アンド・サイエンス・インコーポレイテッド filed Critical センサーズ・フォー・メディシン・アンド・サイエンス・インコーポレイテッド
Publication of JP2002506973A publication Critical patent/JP2002506973A/ja
Publication of JP2002506973A5 publication Critical patent/JP2002506973A5/ja
Application granted granted Critical
Publication of JP4625180B2 publication Critical patent/JP4625180B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Images

Classifications

    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K11/00—Luminescent, e.g. electroluminescent, chemiluminescent materials
    • C09K11/06—Luminescent, e.g. electroluminescent, chemiluminescent materials containing organic luminescent materials
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02—Boron compounds
    • C07F5/025—Boronic and borinic acid compounds
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/66—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood sugars, e.g. galactose
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
    • Y10T436/143333—Saccharide [e.g., DNA, etc.]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
    • Y10T436/143333—Saccharide [e.g., DNA, etc.]
    • Y10T436/144444—Glucose

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Materials Engineering (AREA)
  • Diabetes (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
JP2000535930A 1998-03-11 1999-03-11 被分析物の蛍光ランタニドキレートによる検出 Expired - Fee Related JP4625180B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US3796098A 1998-03-11 1998-03-11
US09/037,960 1998-03-11
PCT/US1999/005290 WO1999046600A1 (en) 1998-03-11 1999-03-11 Detection of analytes by fluorescent lanthanide chelates

Publications (3)

Publication Number Publication Date
JP2002506973A JP2002506973A (ja) 2002-03-05
JP2002506973A5 JP2002506973A5 (enExample) 2006-04-27
JP4625180B2 true JP4625180B2 (ja) 2011-02-02

Family

ID=21897295

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2000535930A Expired - Fee Related JP4625180B2 (ja) 1998-03-11 1999-03-11 被分析物の蛍光ランタニドキレートによる検出

Country Status (9)

Country Link
US (1) US6344360B1 (enExample)
EP (1) EP1062516A1 (enExample)
JP (1) JP4625180B2 (enExample)
KR (1) KR100718953B1 (enExample)
CN (1) CN1159583C (enExample)
AU (1) AU757901B2 (enExample)
CA (1) CA2322858C (enExample)
TW (1) TWI227323B (enExample)
WO (1) WO1999046600A1 (enExample)

Families Citing this family (55)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69633573T2 (de) 1995-11-22 2005-10-06 Medtronic MiniMed, Inc., Northridge Detektion von biologischen molekülen unter verwendung von chemischer amplifikation und optischem sensor
US6766183B2 (en) 1995-11-22 2004-07-20 Medtronic Minimed, Inc. Long wave fluorophore sensor compounds and other fluorescent sensor compounds in polymers
AU5446098A (en) 1996-11-21 1998-06-10 Lawrence Livermore National Laboratory Detection of biological molecules using boronate-based chemical amplification and optical sensors
US6330464B1 (en) 1998-08-26 2001-12-11 Sensors For Medicine & Science Optical-based sensing devices
FR2792072A1 (fr) * 1999-04-08 2000-10-13 Cis Bio Int Methode homogene de detection ou de determination d'une interaction chimique ou physicochimique
US6673625B2 (en) 1999-09-15 2004-01-06 The Regents Of The University Of California Saccharide sensing molecules having enhanced fluorescent properties
US6682938B1 (en) 1999-09-15 2004-01-27 The Regents Of The University Of California Glucose sensing molecules having selected fluorescent properties
US6774102B1 (en) * 1999-09-29 2004-08-10 Gambro Dialysatoren Gmbh & Co. Kg Extracorporeal endotoxin removal method
WO2001075450A2 (en) * 2000-04-04 2001-10-11 The Regents Of The University Of California Fluorescent lifetime assays for non-invasive quantification of analytes
CN1446222A (zh) 2000-08-04 2003-10-01 医药及科学传感器公司 水环境中分析物的检测
US6653141B2 (en) * 2000-12-05 2003-11-25 The Regents Of The University Of California Polyhydroxyl-substituted organic molecule sensing method and device
US7470420B2 (en) * 2000-12-05 2008-12-30 The Regents Of The University Of California Optical determination of glucose utilizing boronic acid adducts
US6800451B2 (en) * 2001-01-05 2004-10-05 Sensors For Medicine And Science, Inc. Detection of glucose in solutions also containing an alpha-hydroxy acid or a beta-diketone
US20020119581A1 (en) * 2001-01-05 2002-08-29 Daniloff George Y. Detection of analytes
AU2002251944A1 (en) 2001-02-15 2002-09-04 Medtronic Minimed, Inc. Polymers functionalized with fluorescent boronate motifs
JP4729734B2 (ja) * 2001-05-16 2011-07-20 財団法人北九州産業学術推進機構 キドセンサによる重金属イオン測定装置
US9493806B2 (en) 2001-06-01 2016-11-15 Colorado State University Research Foundation Enzymatic biosensing systems
US9493805B2 (en) 2001-06-01 2016-11-15 Colorado State University Research Foundation Enzymatic biosensors with enhanced activity retention for detection of organic compounds
US20050164316A1 (en) * 2001-06-27 2005-07-28 Bray Terry L. Biophotonic sensors and methods of use thereof
US20030215391A1 (en) * 2001-07-19 2003-11-20 Carlos Rabito Fluorescent agents for real-time measurement of organ function
US7045361B2 (en) 2001-09-12 2006-05-16 Medtronic Minimed, Inc. Analyte sensing via acridine-based boronate biosensors
ES2345194T3 (es) * 2002-03-14 2010-09-17 Sensors For Medicine And Science, Inc. Deteccion de glucosa que tambien contienen un alfa hidroxiacido o una beta dicetona.
GB0210535D0 (en) * 2002-05-08 2002-06-19 Novartis Ag Organic compounds
US7108659B2 (en) * 2002-08-01 2006-09-19 Healthetech, Inc. Respiratory analyzer for exercise use
AU2003287735A1 (en) * 2002-11-12 2004-06-03 Argose, Inc. Non-invasive measurement of analytes
US20040106163A1 (en) * 2002-11-12 2004-06-03 Workman Jerome James Non-invasive measurement of analytes
JP4748791B2 (ja) * 2003-02-24 2011-08-17 独立行政法人科学技術振興機構 蛍光性ランタニド錯体
WO2005065241A2 (en) 2003-12-24 2005-07-21 Argose, Inc. Smmr (small molecule metabolite reporters) for use as in vivo glucose biosensors
US7713745B2 (en) * 2004-04-13 2010-05-11 Sensors For Medicine And Science, Inc. Non-covalent immobilization of indicator molecules
DE102004051830B4 (de) 2004-10-25 2007-12-13 Roche Diagnostics Gmbh Multifunktionales Referenzsystem bei Analytbestimmungen durch Fluoreszenz
TWI381162B (zh) * 2005-05-26 2013-01-01 Plagenom Co Ltd A authenticity determination method, an authenticity determination device, a authenticity determination system, and a detection device terminal
JP5057682B2 (ja) * 2006-03-30 2012-10-24 株式会社東芝 照明装置、撮像装置及び携帯端末
GB0613823D0 (en) 2006-07-12 2006-08-23 Univ Durham Assay
US9796998B2 (en) 2007-04-09 2017-10-24 Colorado State University Research Foundation Oxygenase-based biosensing systems for measurement of halogenated alkene concentrations
FR2917226B1 (fr) * 2007-06-06 2009-09-11 Inst Nat Sciences Appliq Procede de marquage de materiaux a base de matrices organiques polymeriques thermoplastiques ou thermodurcissables
US20090247984A1 (en) * 2007-10-24 2009-10-01 Masimo Laboratories, Inc. Use of microneedles for small molecule metabolite reporter delivery
WO2010014505A1 (en) * 2008-07-28 2010-02-04 Sensors For Medicine & Science, Inc. Systems and methods for optical measurement of analyte concentration
US20120190123A1 (en) * 2008-09-10 2012-07-26 National University Corporation NARA Institute of Science and Technology Structural analysis device and structural analysis method
WO2012071471A2 (en) 2010-11-22 2012-05-31 Colorado State University Research Foundation Biosensing systems for measurement of lactose
JP6084172B2 (ja) 2011-03-15 2017-02-22 センセオニクス，インコーポレーテッド 酸化感受性材料の統合的な触媒による保護
US9051598B2 (en) * 2011-05-02 2015-06-09 The Hong Kong University Of Science And Technology Specific detection of D-glucose by a tetraphenylethene-base fluorescent sensor
US9499853B2 (en) 2011-08-02 2016-11-22 Colorado State University Research Foundation Biosensing system with extended lifetime via cofactor recycling
WO2013160547A1 (en) 2012-04-24 2013-10-31 Haermae Harri Method for characterizing and/or determining samples
US9194802B2 (en) 2012-09-14 2015-11-24 Regents Of The University Of Minnesota Luminescent probes having a phenanthridinyl antenna, and methods of use
CA2896749A1 (en) 2012-12-28 2014-07-03 Senseonics, Incorporated Analyte permeable membrane systems for oxidative and optical stability
KR101660399B1 (ko) * 2013-08-23 2016-09-28 주식회사 메디센서 금 나노 입자를 포함하는 형광 입자 및 그 제조방법
US9963556B2 (en) 2013-09-18 2018-05-08 Senseonics, Incorporated Critical point drying of hydrogels in analyte sensors
FI125111B (en) * 2013-11-19 2015-06-15 Kemira Oyj A method for analyzing a sample comprising first and second anticaking agents
FI125102B (en) * 2013-11-19 2015-06-15 Kemira Oyj Method for the determination of an antifouling agent in a sample
CN103881128A (zh) * 2014-03-10 2014-06-25 黄鹏 基于荧光检测方法的原位葡萄糖检测膜的制备方法
ES2998082T3 (en) 2017-08-14 2025-02-19 Senseonics Inc Methods and systems for calculating analyte levels
EP3722379B1 (en) * 2017-09-15 2023-10-11 Dai Nippon Printing Co., Ltd. Ink composition and printed matter
CN112047965B (zh) * 2020-09-09 2022-04-26 黑龙江大学 一种具有激发态配体间质子转移特性的配合物的制备方法及应用
CN115124731B (zh) * 2022-08-12 2023-12-01 复旦大学 一种高值化豆科植物界面超组装SAFs荧光材料的制备方法
CN118955414B (zh) * 2024-10-17 2025-03-18 南昌大学 两亲性Eu配合物及其制备方法与在检测四环素中的应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4637988A (en) * 1981-07-01 1987-01-20 Eastman Kodak Company Fluorescent labels for immunoassay
SE454115B (sv) * 1982-09-13 1988-03-28 Wallac Oy Homogenfasanalys med lantanidkelat som merksubstans
EP0272320B1 (en) * 1986-06-17 1994-03-23 Baxter Diagnostics Inc. Homogeneous fluoroassay methods employing fluorescent background rejection
US5512246A (en) * 1989-09-21 1996-04-30 Anthony P. Russell Method and means for detecting polyhydroxyl compounds
US5246867A (en) * 1992-01-17 1993-09-21 University Of Maryland At Baltimore Determination and quantification of saccharides by luminescence lifetimes and energy transfer
GB2284809B (en) * 1993-11-07 1998-04-29 Japan Res Dev Corp A fluorescent phenylboronic acid suitable for use in the detection of saccharides
US5631364A (en) * 1994-03-31 1997-05-20 Axis Biochemicals Asa Labelled boronic acid derivatives
DE69633573T2 (de) * 1995-11-22 2005-10-06 Medtronic MiniMed, Inc., Northridge Detektion von biologischen molekülen unter verwendung von chemischer amplifikation und optischem sensor
JP2866043B2 (ja) * 1995-12-21 1999-03-08 科学技術振興事業団 カリックスアレーン誘導体
US6001573A (en) * 1996-06-14 1999-12-14 Packard Bioscience B.V. Use of porphyrins as a universal label

Also Published As

Publication number Publication date
AU3078599A (en) 1999-09-27
TWI227323B (en) 2005-02-01
WO1999046600A1 (en) 1999-09-16
KR20010041855A (ko) 2001-05-25
CA2322858C (en) 2009-06-02
KR100718953B1 (ko) 2007-05-16
US6344360B1 (en) 2002-02-05
WO1999046600A9 (en) 1999-11-18
CN1159583C (zh) 2004-07-28
CA2322858A1 (en) 1999-09-16
CN1300368A (zh) 2001-06-20
EP1062516A1 (en) 2000-12-27
JP2002506973A (ja) 2002-03-05
AU757901B2 (en) 2003-03-13

Similar Documents

Publication Publication Date Title
JP4625180B2 (ja) 被分析物の蛍光ランタニドキレートによる検出
Nguyen et al. Recent developments of BODIPY-based colorimetric and fluorescent probes for the detection of reactive oxygen/nitrogen species and cancer diagnosis
US5503770A (en) Fluorescent compound suitable for use in the detection of saccharides
DiCesare et al. Chalcone-analogue fluorescent prfobes for saccharides signaling using the boronic acid group
Sun et al. Mitochondria targetable time-gated luminescence probe for singlet oxygen based on a β-diketonate–europium complex
EP1490359B1 (en) Detection of glucose in solutions also containing an alpha-hydroxy acid or a beta-diketone
JP5517624B2 (ja) 耐酸化性指示薬分子
US20020127626A1 (en) Detection of glucose in solutions also containing an alpha-hydroxy acid or a beta-diketone
Hanaoka et al. A Gd3+‐based magnetic resonance imaging contrast agent sensitive to β‐galactosidase activity utilizing a receptor‐induced magnetization enhancement (RIME) phenomenon
JP2883824B2 (ja) ボロン酸基を有する発蛍光性化合物
CN110229165A (zh) 上转换荧光探针罗丹明衍生物及其应用
Jie et al. A new colorimetric, near-infrared fluorescent probe for rapid detection of palladium with high sensitivity and selectivity
Ramki et al. An aggregation-induced emission-based ratiometric fluorescent chemosensor for Hg (II) and its application in Caenorhabditis elegans imaging
Eçik et al. Synthesis of BODIPY-cyclotetraphosphazene triad systems and their sensing behaviors toward Co (II) and Cu (II)
Wang et al. Boronate-based fluorescent probes as a prominent tool for H2O2 sensing and recognition
CN110194951B (zh) 四苯乙烯衍生物荧光探针及其制备方法
Zhang et al. Supramolecular fluorescent probe based on acyclic cucurbituril for detection of cancer Labels in human urine
JP4951759B2 (ja) レドックス応答性発光プローブ及びそれを用いる検出方法
US20020090734A1 (en) Detection of glucose in solutions also containing an alpha-hydroxy acid or a beta-diketone
Zhang et al. Cy5 Dye Cassettes Exhibit Through-Bond Energy Transfer and Enable Ratiometric Fluorescence Sensing
CN110357867B (zh) 一种基于双硫键的谷胱苷肽比率荧光传感器及其制备和应用
MXPA00008892A (en) Detection of analytes by fluorescent lanthanide chelates
Liu et al. Superlong afterglow reporter for the detection of porphyria in whole blood
Kinoshita et al. Stimuli-Responsive AIE-Based Chemosensors
CN118955377A (zh) 具有大斯托克斯位移的萘酐基次氯酸荧光探针及其制备方法和应用

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20060307

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20060307

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20090127

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20090427

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20090508

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20090527

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20090603

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20090626

RD04 Notification of resignation of power of attorney

Free format text: JAPANESE INTERMEDIATE CODE: A7424

Effective date: 20090917

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20091013

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20100113

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20100803

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20100823

RD03 Notification of appointment of power of attorney

Free format text: JAPANESE INTERMEDIATE CODE: A7423

Effective date: 20100823

RD04 Notification of resignation of power of attorney

Free format text: JAPANESE INTERMEDIATE CODE: A7424

Effective date: 20100823

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A821

Effective date: 20100823

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20101012

A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20101105

R150 Certificate of patent or registration of utility model

Free format text: JAPANESE INTERMEDIATE CODE: R150

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20131112

Year of fee payment: 3

LAPS Cancellation because of no payment of annual fees