JP4624562B2 - イオンチャネル機能活性の調節方法 - Google Patents
イオンチャネル機能活性の調節方法 Download PDFInfo
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- JP4624562B2 JP4624562B2 JP2000575514A JP2000575514A JP4624562B2 JP 4624562 B2 JP4624562 B2 JP 4624562B2 JP 2000575514 A JP2000575514 A JP 2000575514A JP 2000575514 A JP2000575514 A JP 2000575514A JP 4624562 B2 JP4624562 B2 JP 4624562B2
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- vpu
- hiv
- ion channel
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4965—Non-condensed pyrazines
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
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- A—HUMAN NECESSITIES
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- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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| PCT/AU1999/000872 WO2000021538A1 (en) | 1998-10-12 | 1999-10-12 | A method of modulating ion channel functional activity |
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| JP2002527397A JP2002527397A (ja) | 2002-08-27 |
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| DE10210206A1 (de) * | 2002-03-01 | 2003-09-04 | Florian Lang | Fertilitätsreduzierung bei Vertebraten |
| AU2003903251A0 (en) * | 2003-06-26 | 2003-07-10 | Biotron Limited | Antiviral compounds and methods |
| EP1646371A4 (en) * | 2003-06-26 | 2010-09-22 | Biotron Ltd | ANTIVIRAL COMPOSITIONS AND METHODS |
| WO2006130806A2 (en) * | 2005-06-01 | 2006-12-07 | University Of Pittsburgh Of The Commonwealth System Of Higher Education | Assay for agonists and antagonists of ion channels and for regulators of genetic expression |
| CN112156753A (zh) * | 2020-09-23 | 2021-01-01 | 中国石油大学(华东) | 石墨烯气凝胶及其制备方法和应用 |
| CN121872955B (zh) * | 2026-03-17 | 2026-07-24 | 安徽纽健生物科技有限公司 | 3-氨基异丁酸衍生物及其制备方法 |
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| US4085211A (en) * | 1975-12-15 | 1978-04-18 | Merck & Co., Inc. | Pyrazinecarboxamides and processes for preparing same |
| WO1990009792A1 (en) * | 1989-03-03 | 1990-09-07 | The General Hospital Corporation | Topical application of amiloride or analogues thereof for treatment of inflammation |
| US5506231A (en) * | 1989-03-31 | 1996-04-09 | The Children's Medical Center Corporation | Treatment of aids dementia, myelopathy and blindness |
| US5215991A (en) * | 1990-01-26 | 1993-06-01 | Allergan, Inc. | Combination of selective alpha-adrenergic agonists and Na+ /H+ ex |
| JPH0725768A (ja) | 1993-07-09 | 1995-01-27 | Mitsubishi Chem Corp | 血管内膜肥厚抑制剤 |
| JPH10500669A (ja) * | 1994-04-12 | 1998-01-20 | アルザ・コーポレーション | サイトカイン阻害薬に関するスクリーニング法 |
| AUPO258196A0 (en) * | 1996-09-27 | 1996-10-17 | Australian National University, The | Method for determining ion channel activity of a substance |
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1999
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2006
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| CN1323212A (zh) | 2001-11-21 |
| CA2345896A1 (en) | 2000-04-20 |
| CN1245161C (zh) | 2006-03-15 |
| US7179803B1 (en) | 2007-02-20 |
| EP1121128A1 (en) | 2001-08-08 |
| CA2345896C (en) | 2009-03-24 |
| NZ510437A (en) | 2005-01-28 |
| EP1121128A4 (en) | 2004-10-27 |
| JP2002527397A (ja) | 2002-08-27 |
| EP1121128B1 (en) | 2013-04-17 |
| WO2000021538A1 (en) | 2000-04-20 |
| AUPP646498A0 (en) | 1998-11-05 |
| US20070112013A1 (en) | 2007-05-17 |
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