JP4619531B2 - Fpアゴニストとして有用な、芳香族のあるc16〜c20が置換されたテトラヒドロプロスタグランジン類 - Google Patents
Fpアゴニストとして有用な、芳香族のあるc16〜c20が置換されたテトラヒドロプロスタグランジン類 Download PDFInfo
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- JP4619531B2 JP4619531B2 JP2000510710A JP2000510710A JP4619531B2 JP 4619531 B2 JP4619531 B2 JP 4619531B2 JP 2000510710 A JP2000510710 A JP 2000510710A JP 2000510710 A JP2000510710 A JP 2000510710A JP 4619531 B2 JP4619531 B2 JP 4619531B2
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- dihydro
- ring
- compounds
- tetranorprostaglandin
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- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
- C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
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- A61P9/12—Antihypertensives
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
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- Health & Medical Sciences (AREA)
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- Life Sciences & Earth Sciences (AREA)
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- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
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- Pharmacology & Pharmacy (AREA)
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- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
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- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Ophthalmology & Optometry (AREA)
- Rheumatology (AREA)
- Epidemiology (AREA)
- Reproductive Health (AREA)
- Cardiology (AREA)
- Dermatology (AREA)
- Urology & Nephrology (AREA)
- Otolaryngology (AREA)
- Pulmonology (AREA)
- Gynecology & Obstetrics (AREA)
- Pregnancy & Childbirth (AREA)
- Heart & Thoracic Surgery (AREA)
- Endocrinology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US5825297P | 1997-09-09 | 1997-09-09 | |
US60/058,252 | 1997-09-09 | ||
PCT/US1998/018594 WO1999012898A1 (en) | 1997-09-09 | 1998-09-04 | Aromatic c16-c20-substituted tetrahydro prostaglandins useful as fp agonists |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
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JP2010145432A Division JP5330324B2 (ja) | 1997-09-09 | 2010-06-25 | Fpアゴニストとして有用な、芳香族のあるc16〜c20が置換されたテトラヒドロプロスタグランジン類 |
Publications (2)
Publication Number | Publication Date |
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JP2001515885A JP2001515885A (ja) | 2001-09-25 |
JP4619531B2 true JP4619531B2 (ja) | 2011-01-26 |
Family
ID=22015635
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2000510710A Expired - Lifetime JP4619531B2 (ja) | 1997-09-09 | 1998-09-04 | Fpアゴニストとして有用な、芳香族のあるc16〜c20が置換されたテトラヒドロプロスタグランジン類 |
JP2010145432A Expired - Lifetime JP5330324B2 (ja) | 1997-09-09 | 2010-06-25 | Fpアゴニストとして有用な、芳香族のあるc16〜c20が置換されたテトラヒドロプロスタグランジン類 |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
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JP2010145432A Expired - Lifetime JP5330324B2 (ja) | 1997-09-09 | 2010-06-25 | Fpアゴニストとして有用な、芳香族のあるc16〜c20が置換されたテトラヒドロプロスタグランジン類 |
Country Status (24)
Country | Link |
---|---|
US (1) | US6048895A (sk) |
EP (1) | EP1012137B1 (sk) |
JP (2) | JP4619531B2 (sk) |
KR (1) | KR20010023838A (sk) |
CN (1) | CN1269784A (sk) |
AR (1) | AR017078A1 (sk) |
AT (1) | ATE227266T1 (sk) |
AU (1) | AU731032B2 (sk) |
BR (1) | BR9812631A (sk) |
CA (1) | CA2303801C (sk) |
CO (1) | CO4970733A1 (sk) |
DE (1) | DE69809268T2 (sk) |
DK (1) | DK1012137T3 (sk) |
HU (1) | HUP0004427A3 (sk) |
ID (1) | ID24845A (sk) |
IL (1) | IL134840A0 (sk) |
NO (1) | NO20001139L (sk) |
NZ (1) | NZ503738A (sk) |
PE (1) | PE123099A1 (sk) |
PL (1) | PL339221A1 (sk) |
SK (1) | SK3382000A3 (sk) |
TR (1) | TR200000673T2 (sk) |
WO (1) | WO1999012898A1 (sk) |
ZA (1) | ZA988232B (sk) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2010254705A (ja) * | 1997-09-09 | 2010-11-11 | Duke Univ | Fpアゴニストとして有用な、芳香族のあるc16〜c20が置換されたテトラヒドロプロスタグランジン類 |
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EP0930296B2 (en) * | 1996-09-17 | 2005-11-02 | Asahi Glass Company Ltd. | Fluorinated prostaglandin derivatives and medicines |
JP4834224B2 (ja) | 1999-03-05 | 2011-12-14 | デューク ユニバーシティ | C16不飽和fp−選択的プロスタグランジン類縁体 |
IL147771A0 (en) | 1999-08-04 | 2002-08-14 | Procter & Gamble | Novel 2-decarboxy-2-phosphinico prostaglandin f analogs |
US20020146439A1 (en) * | 2000-03-31 | 2002-10-10 | Delong Mitchell Anthony | Compositions and methods for treating hair loss using oximyl and hydroxylamino prostaglandins |
US20020013294A1 (en) * | 2000-03-31 | 2002-01-31 | Delong Mitchell Anthony | Cosmetic and pharmaceutical compositions and methods using 2-decarboxy-2-phosphinico derivatives |
US20020037914A1 (en) * | 2000-03-31 | 2002-03-28 | Delong Mitchell Anthony | Compositions and methods for treating hair loss using C16-C20 aromatic tetrahydro prostaglandins |
US20020172693A1 (en) * | 2000-03-31 | 2002-11-21 | Delong Michell Anthony | Compositions and methods for treating hair loss using non-naturally occurring prostaglandins |
KR100437873B1 (ko) * | 2001-05-08 | 2004-06-26 | 연성정밀화학(주) | 프로스타글란딘 유도체의 제조방법 및 그의 입체특이적출발물질 |
US6905827B2 (en) * | 2001-06-08 | 2005-06-14 | Expression Diagnostics, Inc. | Methods and compositions for diagnosing or monitoring auto immune and chronic inflammatory diseases |
WO2006047466A2 (en) * | 2004-10-21 | 2006-05-04 | Duke University | Ophthamological drugs |
US20070254920A1 (en) * | 2006-04-26 | 2007-11-01 | Aerie Pharmaceuticals, Inc. | Prodrug derivatives of acids using alcohols with homotopic hydroxy groups and methods for their preparation and use |
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WO2010039535A1 (en) * | 2008-09-23 | 2010-04-08 | Meta Cosmetics, Llc | Compositions and methods to treat epithelial-related conditions |
JP2011502152A (ja) * | 2007-10-31 | 2011-01-20 | パメラ リプキン | プロスタグランジン類似体組成物及び上皮関連症状の治療方法 |
US8450344B2 (en) | 2008-07-25 | 2013-05-28 | Aerie Pharmaceuticals, Inc. | Beta- and gamma-amino-isoquinoline amide compounds and substituted benzamide compounds |
US8623918B2 (en) * | 2008-10-29 | 2014-01-07 | Novaer Holdings, Inc. | Amino acid salts of prostaglandins |
JP2012507552A (ja) | 2008-10-29 | 2012-03-29 | アエリエ・ファーマシューティカルズ・インコーポレーテッド | プロスタグラジンのアミノ酸塩 |
US8722739B2 (en) | 2008-10-29 | 2014-05-13 | Novaer Holdings, Inc. | Amino acid salts of prostaglandins |
US20110293549A1 (en) | 2009-02-03 | 2011-12-01 | Athena Cosmetics, Inc. | Composition, method and kit for enhancing hair |
ES2672624T3 (es) | 2009-05-01 | 2018-06-15 | Aerie Pharmaceuticals, Inc. | Inhibidores de mecanismo doble para el tratamiento de enfermedades |
CN103864653A (zh) * | 2012-12-10 | 2014-06-18 | 韩冰 | 一类降低眼压的化合物及其用途 |
FI3811943T3 (fi) | 2013-03-15 | 2023-04-14 | Aerie Pharmaceuticals Inc | Yhdiste käytettäväksi silmäsairauksien hoidossa |
US9643927B1 (en) | 2015-11-17 | 2017-05-09 | Aerie Pharmaceuticals, Inc. | Process for the preparation of kinase inhibitors and intermediates thereof |
CN109640966A (zh) | 2016-08-31 | 2019-04-16 | 爱瑞制药公司 | 眼用组合物 |
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US11427563B2 (en) | 2018-09-14 | 2022-08-30 | Aerie Pharmaceuticals, Inc. | Aryl cyclopropyl-amino-isoquinolinyl amide compounds |
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1998
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- 1998-09-04 NZ NZ503738A patent/NZ503738A/en unknown
- 1998-09-04 US US09/148,538 patent/US6048895A/en not_active Expired - Lifetime
- 1998-09-04 HU HU0004427A patent/HUP0004427A3/hu unknown
- 1998-09-04 DK DK98944783T patent/DK1012137T3/da active
- 1998-09-04 CN CN98808988A patent/CN1269784A/zh active Pending
- 1998-09-04 AU AU92240/98A patent/AU731032B2/en not_active Expired
- 1998-09-04 TR TR2000/00673T patent/TR200000673T2/xx unknown
- 1998-09-04 JP JP2000510710A patent/JP4619531B2/ja not_active Expired - Lifetime
- 1998-09-04 CA CA002303801A patent/CA2303801C/en not_active Expired - Lifetime
- 1998-09-04 AT AT98944783T patent/ATE227266T1/de not_active IP Right Cessation
- 1998-09-04 ID IDW20000641A patent/ID24845A/id unknown
- 1998-09-04 SK SK338-2000A patent/SK3382000A3/sk unknown
- 1998-09-04 IL IL13484098A patent/IL134840A0/xx unknown
- 1998-09-04 PL PL98339221A patent/PL339221A1/xx unknown
- 1998-09-04 BR BR9812631-8A patent/BR9812631A/pt not_active IP Right Cessation
- 1998-09-04 DE DE69809268T patent/DE69809268T2/de not_active Expired - Lifetime
- 1998-09-04 KR KR1020007002513A patent/KR20010023838A/ko not_active Application Discontinuation
- 1998-09-04 EP EP98944783A patent/EP1012137B1/en not_active Expired - Lifetime
- 1998-09-08 PE PE1998000844A patent/PE123099A1/es not_active Application Discontinuation
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- 1998-09-09 ZA ZA988232A patent/ZA988232B/xx unknown
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2000
- 2000-03-06 NO NO20001139A patent/NO20001139L/no not_active Application Discontinuation
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2010
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2010254705A (ja) * | 1997-09-09 | 2010-11-11 | Duke Univ | Fpアゴニストとして有用な、芳香族のあるc16〜c20が置換されたテトラヒドロプロスタグランジン類 |
Also Published As
Publication number | Publication date |
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WO1999012898A1 (en) | 1999-03-18 |
CO4970733A1 (es) | 2000-11-07 |
BR9812631A (pt) | 2000-08-22 |
ATE227266T1 (de) | 2002-11-15 |
ZA988232B (en) | 1999-03-09 |
AU731032B2 (en) | 2001-03-22 |
TR200000673T2 (tr) | 2000-11-21 |
US6048895A (en) | 2000-04-11 |
DK1012137T3 (da) | 2003-03-10 |
NZ503738A (en) | 2001-05-25 |
CN1269784A (zh) | 2000-10-11 |
DE69809268T2 (de) | 2003-08-28 |
JP2010254705A (ja) | 2010-11-11 |
HUP0004427A3 (en) | 2001-09-28 |
EP1012137B1 (en) | 2002-11-06 |
ID24845A (id) | 2000-08-24 |
EP1012137A1 (en) | 2000-06-28 |
JP2001515885A (ja) | 2001-09-25 |
IL134840A0 (en) | 2001-05-20 |
CA2303801A1 (en) | 1999-03-18 |
CA2303801C (en) | 2005-05-10 |
AR017078A1 (es) | 2001-08-22 |
KR20010023838A (ko) | 2001-03-26 |
AU9224098A (en) | 1999-03-29 |
HUP0004427A2 (hu) | 2001-05-28 |
NO20001139L (no) | 2000-05-04 |
NO20001139D0 (no) | 2000-03-06 |
PE123099A1 (es) | 2000-02-02 |
PL339221A1 (en) | 2000-12-04 |
DE69809268D1 (de) | 2002-12-12 |
JP5330324B2 (ja) | 2013-10-30 |
SK3382000A3 (en) | 2000-10-09 |
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