JP4588873B2 - 銅塩、四級アンモニウム化合物及び過酸化物を含有する、動物の蹄の感染症治療用殺菌組成物 - Google Patents
銅塩、四級アンモニウム化合物及び過酸化物を含有する、動物の蹄の感染症治療用殺菌組成物 Download PDFInfo
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- JP4588873B2 JP4588873B2 JP2000511508A JP2000511508A JP4588873B2 JP 4588873 B2 JP4588873 B2 JP 4588873B2 JP 2000511508 A JP2000511508 A JP 2000511508A JP 2000511508 A JP2000511508 A JP 2000511508A JP 4588873 B2 JP4588873 B2 JP 4588873B2
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- composition
- weight
- quaternary ammonium
- amount
- ammonium compound
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- Expired - Fee Related
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- 239000000203 mixture Substances 0.000 title claims description 141
- 210000000003 hoof Anatomy 0.000 title claims description 67
- 150000003856 quaternary ammonium compounds Chemical class 0.000 title claims description 30
- 150000001879 copper Chemical class 0.000 title claims description 26
- 208000015181 infectious disease Diseases 0.000 title claims description 22
- 241001465754 Metazoa Species 0.000 title claims description 21
- 150000002978 peroxides Chemical class 0.000 title claims description 16
- 230000000844 anti-bacterial effect Effects 0.000 title claims description 14
- 238000000034 method Methods 0.000 claims description 31
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical group OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 claims description 28
- 229910000365 copper sulfate Inorganic materials 0.000 claims description 10
- ARUVKPQLZAKDPS-UHFFFAOYSA-L copper(II) sulfate Chemical group [Cu+2].[O-][S+2]([O-])([O-])[O-] ARUVKPQLZAKDPS-UHFFFAOYSA-L 0.000 claims description 10
- 230000002265 prevention Effects 0.000 claims description 10
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 claims description 9
- AEMRFAOFKBGASW-UHFFFAOYSA-N Glycolic acid Chemical compound OCC(O)=O AEMRFAOFKBGASW-UHFFFAOYSA-N 0.000 claims description 8
- NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 claims description 8
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- 241000605721 Dichelobacter nodosus Species 0.000 claims description 6
- KWYUFKZDYYNOTN-UHFFFAOYSA-M Potassium hydroxide Chemical compound [OH-].[K+] KWYUFKZDYYNOTN-UHFFFAOYSA-M 0.000 claims description 6
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims description 6
- 241000605952 Fusobacterium necrophorum Species 0.000 claims description 5
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 claims description 4
- QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 claims description 4
- 229910000147 aluminium phosphate Inorganic materials 0.000 claims description 4
- 239000003795 chemical substances by application Substances 0.000 claims description 4
- 229960004275 glycolic acid Drugs 0.000 claims description 4
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 claims description 4
- 208000010801 foot rot Diseases 0.000 claims description 3
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- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 claims 5
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 claims 4
- 208000035473 Communicable disease Diseases 0.000 claims 2
- QGZKDVFQNNGYKY-UHFFFAOYSA-O Ammonium Chemical compound [NH4+] QGZKDVFQNNGYKY-UHFFFAOYSA-O 0.000 claims 1
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- 229960000625 oxytetracycline Drugs 0.000 description 7
- IWVCMVBTMGNXQD-PXOLEDIWSA-N oxytetracycline Chemical compound C1=CC=C2[C@](O)(C)[C@H]3[C@H](O)[C@H]4[C@H](N(C)C)C(O)=C(C(N)=O)C(=O)[C@@]4(O)C(O)=C3C(=O)C2=C1O IWVCMVBTMGNXQD-PXOLEDIWSA-N 0.000 description 7
- 235000019366 oxytetracycline Nutrition 0.000 description 7
- IWVCMVBTMGNXQD-UHFFFAOYSA-N terramycin dehydrate Natural products C1=CC=C2C(O)(C)C3C(O)C4C(N(C)C)C(O)=C(C(N)=O)C(=O)C4(O)C(O)=C3C(=O)C2=C1O IWVCMVBTMGNXQD-UHFFFAOYSA-N 0.000 description 7
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- 206010007882 Cellulitis Diseases 0.000 description 2
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical class [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 description 2
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- 239000010949 copper Substances 0.000 description 2
- 229910052802 copper Inorganic materials 0.000 description 2
- YEOCHZFPBYUXMC-UHFFFAOYSA-L copper benzoate Chemical compound [Cu+2].[O-]C(=O)C1=CC=CC=C1.[O-]C(=O)C1=CC=CC=C1 YEOCHZFPBYUXMC-UHFFFAOYSA-L 0.000 description 2
- JZCCFEFSEZPSOG-UHFFFAOYSA-L copper(II) sulfate pentahydrate Chemical compound O.O.O.O.O.[Cu+2].[O-]S([O-])(=O)=O JZCCFEFSEZPSOG-UHFFFAOYSA-L 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
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- NLXLAEXVIDQMFP-UHFFFAOYSA-N Ammonia chloride Chemical compound [NH4+].[Cl-] NLXLAEXVIDQMFP-UHFFFAOYSA-N 0.000 description 1
- BVKZGUZCCUSVTD-UHFFFAOYSA-M Bicarbonate Chemical compound OC([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-M 0.000 description 1
- 241000283707 Capra Species 0.000 description 1
- VMQMZMRVKUZKQL-UHFFFAOYSA-N Cu+ Chemical compound [Cu+] VMQMZMRVKUZKQL-UHFFFAOYSA-N 0.000 description 1
- RGHNJXZEOKUKBD-SQOUGZDYSA-M D-gluconate Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C([O-])=O RGHNJXZEOKUKBD-SQOUGZDYSA-M 0.000 description 1
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- OJMMVQQUTAEWLP-UHFFFAOYSA-N Lincomycin Natural products CN1CC(CCC)CC1C(=O)NC(C(C)O)C1C(O)C(O)C(O)C(SC)O1 OJMMVQQUTAEWLP-UHFFFAOYSA-N 0.000 description 1
- IOVCWXUNBOPUCH-UHFFFAOYSA-M Nitrite anion Chemical compound [O-]N=O IOVCWXUNBOPUCH-UHFFFAOYSA-M 0.000 description 1
- 229910019142 PO4 Inorganic materials 0.000 description 1
- 241001494479 Pecora Species 0.000 description 1
- 229930182555 Penicillin Natural products 0.000 description 1
- JGSARLDLIJGVTE-MBNYWOFBSA-N Penicillin G Chemical compound N([C@H]1[C@H]2SC([C@@H](N2C1=O)C(O)=O)(C)C)C(=O)CC1=CC=CC=C1 JGSARLDLIJGVTE-MBNYWOFBSA-N 0.000 description 1
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- AVKUERGKIZMTKX-NJBDSQKTSA-N ampicillin Chemical compound C1([C@@H](N)C(=O)N[C@H]2[C@H]3SC([C@@H](N3C2=O)C(O)=O)(C)C)=CC=CC=C1 AVKUERGKIZMTKX-NJBDSQKTSA-N 0.000 description 1
- 229960000723 ampicillin Drugs 0.000 description 1
- -1 and use a foot bath Substances 0.000 description 1
- 150000001450 anions Chemical class 0.000 description 1
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- 125000003118 aryl group Chemical group 0.000 description 1
- 239000003899 bactericide agent Substances 0.000 description 1
- RCTOVWPTGOZSPJ-UHFFFAOYSA-N benzyl(ethyl)azanium;chloride Chemical compound Cl.CCNCC1=CC=CC=C1 RCTOVWPTGOZSPJ-UHFFFAOYSA-N 0.000 description 1
- OCBHHZMJRVXXQK-UHFFFAOYSA-M benzyl-dimethyl-tetradecylazanium;chloride Chemical compound [Cl-].CCCCCCCCCCCCCC[N+](C)(C)CC1=CC=CC=C1 OCBHHZMJRVXXQK-UHFFFAOYSA-M 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
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- 125000004432 carbon atom Chemical group C* 0.000 description 1
- 231100000357 carcinogen Toxicity 0.000 description 1
- 239000003183 carcinogenic agent Substances 0.000 description 1
- 150000001805 chlorine compounds Chemical class 0.000 description 1
- 208000037976 chronic inflammation Diseases 0.000 description 1
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- 210000000078 claw Anatomy 0.000 description 1
- 239000003086 colorant Substances 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- ORTQZVOHEJQUHG-UHFFFAOYSA-L copper(II) chloride Chemical compound Cl[Cu]Cl ORTQZVOHEJQUHG-UHFFFAOYSA-L 0.000 description 1
- XTVVROIMIGLXTD-UHFFFAOYSA-N copper(II) nitrate Chemical compound [Cu+2].[O-][N+]([O-])=O.[O-][N+]([O-])=O XTVVROIMIGLXTD-UHFFFAOYSA-N 0.000 description 1
- OPQARKPSCNTWTJ-UHFFFAOYSA-L copper(ii) acetate Chemical compound [Cu+2].CC([O-])=O.CC([O-])=O OPQARKPSCNTWTJ-UHFFFAOYSA-L 0.000 description 1
- SBNWNVYHPPJBBD-UHFFFAOYSA-N copper;2,2,2-trichloroacetic acid Chemical compound [Cu].OC(=O)C(Cl)(Cl)Cl SBNWNVYHPPJBBD-UHFFFAOYSA-N 0.000 description 1
- HFDWIMBEIXDNQS-UHFFFAOYSA-L copper;diformate Chemical compound [Cu+2].[O-]C=O.[O-]C=O HFDWIMBEIXDNQS-UHFFFAOYSA-L 0.000 description 1
- 238000003977 dairy farming Methods 0.000 description 1
- 238000000354 decomposition reaction Methods 0.000 description 1
- 239000000645 desinfectant Substances 0.000 description 1
- 230000000249 desinfective effect Effects 0.000 description 1
- FWBOFUGDKHMVPI-UHFFFAOYSA-K dicopper;2-oxidopropane-1,2,3-tricarboxylate Chemical compound [Cu+2].[Cu+2].[O-]C(=O)CC([O-])(C([O-])=O)CC([O-])=O FWBOFUGDKHMVPI-UHFFFAOYSA-K 0.000 description 1
- 208000023867 digital dermatitis in cattle Diseases 0.000 description 1
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- 210000003608 fece Anatomy 0.000 description 1
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- 210000000610 foot bone Anatomy 0.000 description 1
- 210000003108 foot joint Anatomy 0.000 description 1
- 230000002070 germicidal effect Effects 0.000 description 1
- 229940050410 gluconate Drugs 0.000 description 1
- 235000019447 hydroxyethyl cellulose Nutrition 0.000 description 1
- 230000002458 infectious effect Effects 0.000 description 1
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- 229960005287 lincomycin Drugs 0.000 description 1
- OJMMVQQUTAEWLP-KIDUDLJLSA-N lincomycin Chemical compound CN1C[C@H](CCC)C[C@H]1C(=O)N[C@H]([C@@H](C)O)[C@@H]1[C@H](O)[C@H](O)[C@@H](O)[C@@H](SC)O1 OJMMVQQUTAEWLP-KIDUDLJLSA-N 0.000 description 1
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- UNFWWIHTNXNPBV-WXKVUWSESA-N spectinomycin Chemical compound O([C@@H]1[C@@H](NC)[C@@H](O)[C@H]([C@@H]([C@H]1O1)O)NC)[C@]2(O)[C@H]1O[C@H](C)CC2=O UNFWWIHTNXNPBV-WXKVUWSESA-N 0.000 description 1
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- 229910000368 zinc sulfate Inorganic materials 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/40—Peroxides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/02—Local antiseptics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Inorganic Chemistry (AREA)
- Oncology (AREA)
- Epidemiology (AREA)
- Communicable Diseases (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Physical Education & Sports Medicine (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US938,013 | 1997-09-12 | ||
| US08/938,013 US5780064A (en) | 1997-09-12 | 1997-09-12 | Germicidal compositions for the treatment of animal infectious diseases of the hoof |
| PCT/US1998/018751 WO1999013888A1 (en) | 1997-09-12 | 1998-09-09 | Germicidal compositions for the treatment of animal infectious diseases of the hoof, comprising a copper salt, a quaternary ammonium compound and a peroxide |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2003528798A JP2003528798A (ja) | 2003-09-30 |
| JP2003528798A5 JP2003528798A5 (enExample) | 2006-01-05 |
| JP4588873B2 true JP4588873B2 (ja) | 2010-12-01 |
Family
ID=25470732
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000511508A Expired - Fee Related JP4588873B2 (ja) | 1997-09-12 | 1998-09-09 | 銅塩、四級アンモニウム化合物及び過酸化物を含有する、動物の蹄の感染症治療用殺菌組成物 |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US5780064A (enExample) |
| EP (1) | EP1027062B1 (enExample) |
| JP (1) | JP4588873B2 (enExample) |
| KR (1) | KR100637295B1 (enExample) |
| AR (1) | AR013488A1 (enExample) |
| AU (1) | AU739193B2 (enExample) |
| BR (1) | BR9812437A (enExample) |
| DE (1) | DE69828078T2 (enExample) |
| IL (1) | IL134986A (enExample) |
| NZ (1) | NZ503340A (enExample) |
| PL (1) | PL192420B1 (enExample) |
| RU (1) | RU2235546C2 (enExample) |
| WO (1) | WO1999013888A1 (enExample) |
Families Citing this family (61)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6667040B2 (en) | 1997-09-08 | 2003-12-23 | University Technologies International, Inc. | Bovine footrot treatment and prevention |
| US6241992B1 (en) * | 1997-09-08 | 2001-06-05 | University Technologies International, Inc. | Bovine footrot treatment and prevention |
| JP4618830B2 (ja) * | 1999-07-27 | 2011-01-26 | 白石カルシウム株式会社 | 牛蹄保護製剤 |
| US6627657B1 (en) | 2000-03-22 | 2003-09-30 | Ecolab Inc. | Peroxycarboxylic acid compositions and methods of use against microbial spores |
| US6444707B1 (en) | 2000-08-22 | 2002-09-03 | West Agro | Topically applied hoof treatment composition and concentrate |
| RU2180572C1 (ru) * | 2000-09-14 | 2002-03-20 | Чухаджян Гарник Алексанович | Антимикробное средство и способ его получения |
| GB0104153D0 (en) * | 2001-02-20 | 2001-04-11 | Reckitt Benckiser Inc | Improvements in or relating to organic compositions |
| WO2002098231A1 (en) * | 2001-06-01 | 2002-12-12 | Ring Terry A | Method and apparatus for preventing bacteria and algae growth in water |
| EP1399128B1 (en) * | 2001-06-15 | 2006-08-30 | Innovent Technology Limited | Composition for the treatment of diseases which affect animals' hooves |
| US20110129545A1 (en) * | 2001-12-20 | 2011-06-02 | Frank Miele | Method of protecting vascular plants against pathogens |
| US9266785B2 (en) | 2001-12-20 | 2016-02-23 | Zero Gravity Solutions, Inc. | Bioavailable minerals for plant health |
| US7163709B2 (en) * | 2001-12-20 | 2007-01-16 | Robert Cook | Composition for disinfection of plants, animals, humans, byproducts of plants and animals and articles infected with pathogens and method of producing and application of same |
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- 1997-09-12 US US08/938,013 patent/US5780064A/en not_active Expired - Lifetime
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1998
- 1998-09-09 NZ NZ503340A patent/NZ503340A/xx unknown
- 1998-09-09 PL PL339217A patent/PL192420B1/pl not_active IP Right Cessation
- 1998-09-09 JP JP2000511508A patent/JP4588873B2/ja not_active Expired - Fee Related
- 1998-09-09 BR BR9812437-4A patent/BR9812437A/pt not_active Application Discontinuation
- 1998-09-09 KR KR1020007002601A patent/KR100637295B1/ko not_active Expired - Fee Related
- 1998-09-09 DE DE69828078T patent/DE69828078T2/de not_active Expired - Fee Related
- 1998-09-09 EP EP98944820A patent/EP1027062B1/en not_active Expired - Lifetime
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- 1998-09-09 RU RU2000106753/13A patent/RU2235546C2/ru not_active IP Right Cessation
- 1998-09-09 WO PCT/US1998/018751 patent/WO1999013888A1/en not_active Ceased
- 1998-09-09 IL IL13498698A patent/IL134986A/xx not_active IP Right Cessation
- 1998-09-11 AR ARP980104550A patent/AR013488A1/es active IP Right Grant
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| AU9227098A (en) | 1999-04-05 |
| PL339217A1 (en) | 2000-12-04 |
| WO1999013888A1 (en) | 1999-03-25 |
| AR013488A1 (es) | 2000-12-27 |
| KR20010030584A (ko) | 2001-04-16 |
| KR100637295B1 (ko) | 2006-10-23 |
| EP1027062A1 (en) | 2000-08-16 |
| IL134986A0 (en) | 2001-05-20 |
| US5780064A (en) | 1998-07-14 |
| RU2235546C2 (ru) | 2004-09-10 |
| PL192420B1 (pl) | 2006-10-31 |
| AU739193B2 (en) | 2001-10-04 |
| BR9812437A (pt) | 2001-11-20 |
| DE69828078D1 (de) | 2005-01-13 |
| DE69828078T2 (de) | 2005-11-03 |
| EP1027062B1 (en) | 2004-12-08 |
| NZ503340A (en) | 2002-08-28 |
| IL134986A (en) | 2005-07-25 |
| JP2003528798A (ja) | 2003-09-30 |
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