JP4583027B2 - 標的材料の蛍光検出用標識としてのアクリドン誘導体 - Google Patents

標的材料の蛍光検出用標識としてのアクリドン誘導体 Download PDF

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JP4583027B2
JP4583027B2 JP2003502493A JP2003502493A JP4583027B2 JP 4583027 B2 JP4583027 B2 JP 4583027B2 JP 2003502493 A JP2003502493 A JP 2003502493A JP 2003502493 A JP2003502493 A JP 2003502493A JP 4583027 B2 JP4583027 B2 JP 4583027B2
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dye
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fluorescence
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JP2005500406A (ja
JP2005500406A5 (enExample
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ジョン・アンソニー・スミス
リチャード・マーティン・ウエスト
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ジーイー・ヘルスケア・ユーケイ・リミテッド
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B15/00—Acridine dyes

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Organic Chemistry (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
JP2003502493A 2001-06-04 2002-05-30 標的材料の蛍光検出用標識としてのアクリドン誘導体 Expired - Fee Related JP4583027B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0113435.2A GB0113435D0 (en) 2001-06-04 2001-06-04 Acridone derivatives as labels for fluorescence detection of target materials
PCT/GB2002/002509 WO2002099424A2 (en) 2001-06-04 2002-05-30 Acridone derivatives as labels for fluorescence detection of target materials

Publications (3)

Publication Number Publication Date
JP2005500406A JP2005500406A (ja) 2005-01-06
JP2005500406A5 JP2005500406A5 (enExample) 2006-01-05
JP4583027B2 true JP4583027B2 (ja) 2010-11-17

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JP2003502493A Expired - Fee Related JP4583027B2 (ja) 2001-06-04 2002-05-30 標的材料の蛍光検出用標識としてのアクリドン誘導体

Country Status (6)

Country Link
US (3) US20040191792A1 (enExample)
EP (1) EP1392776A2 (enExample)
JP (1) JP4583027B2 (enExample)
CA (2) CA2754169A1 (enExample)
GB (2) GB0113435D0 (enExample)
WO (1) WO2002099424A2 (enExample)

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GB0208989D0 (en) 2002-04-19 2002-05-29 Amersham Biosciences Uk Ltd Methods for measuring enzyme activity
GB0217562D0 (en) * 2002-07-30 2002-09-11 Amersham Biosciences Uk Ltd Site-specific labelling of proteins using acridone and quinacridone lifetime dyes
GB0317743D0 (en) 2003-07-30 2003-09-03 Amersham Biosciences Uk Ltd Method for measuring aromatase activity
US7671218B2 (en) * 2004-08-13 2010-03-02 Elitech Holdings B.V. Phosphonate fluorescent dyes and conjugates
US7767834B2 (en) * 2004-08-13 2010-08-03 Elitech Holding B.V. Phosphonylated fluorescent dyes and conjugates
GB0421693D0 (en) 2004-09-30 2004-11-03 Amersham Biosciences Uk Ltd Method for measuring binding of a test compound to a G-protein coupled receptor
CN100386624C (zh) * 2005-01-27 2008-05-07 中国科学院大连化学物理研究所 一种荧光试剂的制备方法
GB0505777D0 (en) * 2005-03-22 2005-04-27 Amersham Biosciences Uk Ltd Enzyme detection method and reagent
JP4392502B2 (ja) * 2005-06-10 2010-01-06 国立大学法人 岡山大学 蛍光性アミノ酸誘導体
WO2007049057A2 (en) * 2005-10-28 2007-05-03 Iti Scotland Limited Novel fluorescent dyes and uses thereof
GB0601183D0 (en) * 2006-01-20 2006-03-01 Perkinelmer Ltd Improvements in and relating to imaging
JP2008013456A (ja) 2006-07-04 2008-01-24 Okayama Univ 新規蛍光性アミノ酸誘導体およびその製造方法
US20100173332A1 (en) * 2006-09-07 2010-07-08 Auckland Uniservices Limited Method for the Fluorescent Detection of Nitroreductase Activity Using Nitro-Substituted Aromatic Compounds
US10872686B2 (en) 2007-02-22 2020-12-22 WellDoc, Inc. Systems and methods for disease control and management
US10860943B2 (en) 2007-02-22 2020-12-08 WellDoc, Inc. Systems and methods for disease control and management
GB0712109D0 (en) * 2007-06-22 2007-08-01 Edinburgh Instr Fluorescence lifetime and fluorescence assays
WO2009112791A1 (en) * 2008-03-14 2009-09-17 Assaymetrics Limited Fluorogenic peptides and their method of production
US8828678B2 (en) 2010-11-16 2014-09-09 Enzo Life Sciences, Inc. Self-immolative probes for enzyme activity detection
WO2012129507A1 (en) 2011-03-24 2012-09-27 WellDoc, Inc. Adaptive analytical behavioral and health assistant system and related method of use
GB201122099D0 (en) 2011-12-22 2012-02-01 Almac Sciences Scotland Ltd Dyes
US11361857B2 (en) 2013-06-26 2022-06-14 WellDoc, Inc. Systems and methods for creating and selecting models for predicting medical conditions
US20150006192A1 (en) 2013-06-26 2015-01-01 WellDoc, Inc. Systems and methods for clinical decision-making
JP6226318B2 (ja) * 2013-09-02 2017-11-08 株式会社 資生堂 光学分割用化合物、光学分割用試薬、光学分割する方法及び光学異性体
EP3072975A4 (en) * 2013-11-21 2017-05-03 The University of Tokyo Method for detecting fluorescence or absorbance, method for suppressing background, method for measuring adp, method for measuring activity of adp-synthesizing enzyme, and method for measuring activity of glucosyltransferase
US11414387B2 (en) 2017-11-20 2022-08-16 Stingthera, Inc. Oxoacridinyl acetic acid derivatives and methods of use
WO2019100061A1 (en) 2017-11-20 2019-05-23 Silicon Swat, Inc. Oxoacridinyl acetic acid derivatives and methods of use
AU2019425175A1 (en) 2019-01-21 2021-08-19 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Advanced methods for automated high-performance identification of carbohydrates and carbohydrate mixture composition patterns and systems therefore as well as methods for calibration of multi wavelength fluorescence detection systems therefore, based on new fluorescent dyes
EP3914650A1 (en) 2019-01-21 2021-12-01 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Sulfonated 2(7)-aminoacridone and 1-aminopyrene dyes and their use as fluorescent tags, in particular for carbohydrate analysis
US20230040324A1 (en) 2019-12-06 2023-02-09 Max-Planck-Gesellschaft Zur Foerderung Der Wissenschaften E.V. Aminoacridine and aminopyrene dyes and their use as fluorescent tags, in particular for carbohydrate analysis
DE102021207928A1 (de) * 2021-07-23 2023-02-09 Continental Reifen Deutschland Gmbh Verbindung, Verfahren zu deren Herstellung sowie Verwendung der Verbindung als Alterungsschutzmittel und/oder Ozonschutzmittel und/oder Farbstoff
EP4663627A1 (en) 2023-02-06 2025-12-17 NOF Corporation Amine hydrochloride having maleimide group, and method for producing same
US11866412B1 (en) 2023-03-03 2024-01-09 King Faisal University Acridin-9-one compounds as antibacterial agents

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GB649147A (en) 1948-03-22 1951-01-17 Ward Blenkinsop & Co Ltd Improvements in or relating to the production of substituted diphenylamine 2-monocarboxylic acids
FR1192397A (fr) * 1957-07-19 1959-10-26 Ciba Geigy Nouveaux colorants solubles dans l'eau, leur préparation et leur utilisation
US3681360A (en) * 1971-04-09 1972-08-01 Hoffmann La Roche Antiviral substituted acridanones
US5268486A (en) * 1986-04-18 1993-12-07 Carnegie-Mellon Unversity Method for labeling and detecting materials employing arylsulfonate cyanine dyes
US5262545A (en) * 1989-03-09 1993-11-16 Molecular Probes, Inc. Fluorescent chloramphenicol derivatives for determination of chloramphenicol acetyltransferase activity
WO1992011531A1 (en) 1990-12-22 1992-07-09 Glyko, Inc. Analysis of carbohydrates using 2-aminoacridone
US5296599A (en) * 1991-09-19 1994-03-22 Millipore Corporation Activated carbamates compounds
EP0552108B1 (en) * 1992-01-17 1999-11-10 Lakowicz, Joseph R. Energy transfer phase-modulation fluoro-immunoassay
US5472582A (en) * 1993-04-23 1995-12-05 Astromed Limited Analysis of carbohydrates using 2-aminoacridone
JP3690825B2 (ja) * 1993-07-26 2005-08-31 エーザイ株式会社 三環式ヘテロ環含有スルホンアミドおよびスルホン酸エステル誘導体
WO1995003279A1 (en) * 1993-07-26 1995-02-02 Eisai Co., Ltd. Sulfonamide and sulfonic ester derivatives each having tricyclic hetero ring
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US5622821A (en) * 1994-06-29 1997-04-22 The Regents Of The University Of California Luminescent lanthanide chelates and methods of use
JP4111562B2 (ja) * 1995-10-04 2008-07-02 エーザイ・アール・アンド・ディー・マネジメント株式会社 アクリドン系化合物
AU7145396A (en) 1995-10-04 1997-04-28 Eisai Co. Ltd. Acridone compounds

Also Published As

Publication number Publication date
CA2754169A1 (en) 2002-12-12
EP1392776A2 (en) 2004-03-03
JP2005500406A (ja) 2005-01-06
GB2391870A (en) 2004-02-18
GB0113435D0 (en) 2001-07-25
US8034558B2 (en) 2011-10-11
CA2449201C (en) 2011-12-20
CA2449201A1 (en) 2002-12-12
GB2391870B (en) 2005-12-14
GB0326889D0 (en) 2003-12-24
US20080139788A1 (en) 2008-06-12
WO2002099424A3 (en) 2003-12-04
WO2002099424A2 (en) 2002-12-12
US20040191792A1 (en) 2004-09-30
US20120015373A1 (en) 2012-01-19

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