JP4549443B2 - 腫瘍細胞の成長を阻害するための方法および製薬学的組成物 - Google Patents

腫瘍細胞の成長を阻害するための方法および製薬学的組成物 Download PDF

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JP4549443B2
JP4549443B2 JP52700198A JP52700198A JP4549443B2 JP 4549443 B2 JP4549443 B2 JP 4549443B2 JP 52700198 A JP52700198 A JP 52700198A JP 52700198 A JP52700198 A JP 52700198A JP 4549443 B2 JP4549443 B2 JP 4549443B2
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pparγ
benzyl
cells
cancer
dione
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JP2001510462A5 (https=
JP2001510462A (ja
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スピーゲルマン，ブルース・エム
アルテイオク，ソナー
ミユーラー，エリザベツタ
サラフ，パシヤ
トントノズ，ピーター
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Dana Farber Cancer Institute Inc
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/426—1,3-Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
JP52700198A 1996-12-11 1997-12-11 腫瘍細胞の成長を阻害するための方法および製薬学的組成物 Expired - Fee Related JP4549443B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US76655396A 1996-12-11 1996-12-11
US08/766,553 1996-12-11
US08/923,346 US6552055B2 (en) 1996-12-11 1997-09-04 Methods and pharmaceutical compositions for inhibiting tumor cell growth
US08/923,346 1997-09-04
PCT/US1997/022879 WO1998025598A2 (en) 1996-12-11 1997-12-11 Methods and pharmaceutical compositions for inhibiting tumour cell growth

Related Child Applications (1)

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JP2008210954A Division JP4550133B2 (ja) 1996-12-11 2008-08-19 腫瘍細胞の成長を阻害するための方法および製薬学的組成物

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JP2001510462A JP2001510462A (ja) 2001-07-31
JP2001510462A5 JP2001510462A5 (https=) 2005-08-11
JP4549443B2 true JP4549443B2 (ja) 2010-09-22

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JP52700198A Expired - Fee Related JP4549443B2 (ja) 1996-12-11 1997-12-11 腫瘍細胞の成長を阻害するための方法および製薬学的組成物
JP2008210954A Expired - Fee Related JP4550133B2 (ja) 1996-12-11 2008-08-19 腫瘍細胞の成長を阻害するための方法および製薬学的組成物

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US (1) US7635708B2 (https=)
EP (2) EP1410799B1 (https=)
JP (2) JP4549443B2 (https=)
AT (2) ATE253903T1 (https=)
AU (1) AU5601898A (https=)
CA (1) CA2274756C (https=)
DE (2) DE69739828D1 (https=)
WO (1) WO1998025598A2 (https=)

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Publication number Publication date
WO1998025598A2 (en) 1998-06-18
JP4550133B2 (ja) 2010-09-22
ATE462433T1 (de) 2010-04-15
EP0948324A2 (en) 1999-10-13
CA2274756C (en) 2007-03-13
EP1410799B1 (en) 2010-03-31
DE69726182D1 (de) 2003-12-18
EP1410799A1 (en) 2004-04-21
US20030144330A1 (en) 2003-07-31
WO1998025598A3 (en) 1998-07-30
EP0948324B1 (en) 2003-11-12
AU5601898A (en) 1998-07-03
DE69726182T2 (de) 2004-08-12
DE69739828D1 (de) 2010-05-12
ATE253903T1 (de) 2003-11-15
JP2001510462A (ja) 2001-07-31
JP2009063566A (ja) 2009-03-26
US7635708B2 (en) 2009-12-22
CA2274756A1 (en) 1998-06-18

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