ATE253903T1 - Methoden und pharmazeutische zusammenstellungen zur wachstumsverhinderung von tumorzellen enthaltend einen ppar-gamma agonisten und einen map kinase inhibitor - Google Patents

Methoden und pharmazeutische zusammenstellungen zur wachstumsverhinderung von tumorzellen enthaltend einen ppar-gamma agonisten und einen map kinase inhibitor

Info

Publication number
ATE253903T1
ATE253903T1 AT97952407T AT97952407T ATE253903T1 AT E253903 T1 ATE253903 T1 AT E253903T1 AT 97952407 T AT97952407 T AT 97952407T AT 97952407 T AT97952407 T AT 97952407T AT E253903 T1 ATE253903 T1 AT E253903T1
Authority
AT
Austria
Prior art keywords
ppar
agents
growth
preventing
methods
Prior art date
Application number
AT97952407T
Other languages
German (de)
English (en)
Inventor
Bruce M Spiegelman
Soner Altiok
Elisabetta Mueller
Pasha Serraf
Peter Tontonoz
Original Assignee
Dana Farber Cancer Inst Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/923,346 external-priority patent/US6552055B2/en
Application filed by Dana Farber Cancer Inst Inc filed Critical Dana Farber Cancer Inst Inc
Application granted granted Critical
Publication of ATE253903T1 publication Critical patent/ATE253903T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/426—1,3-Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT97952407T 1996-12-11 1997-12-11 Methoden und pharmazeutische zusammenstellungen zur wachstumsverhinderung von tumorzellen enthaltend einen ppar-gamma agonisten und einen map kinase inhibitor ATE253903T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US76655396A 1996-12-11 1996-12-11
US08/923,346 US6552055B2 (en) 1996-12-11 1997-09-04 Methods and pharmaceutical compositions for inhibiting tumor cell growth
PCT/US1997/022879 WO1998025598A2 (en) 1996-12-11 1997-12-11 Methods and pharmaceutical compositions for inhibiting tumour cell growth

Publications (1)

Publication Number Publication Date
ATE253903T1 true ATE253903T1 (de) 2003-11-15

Family

ID=27117766

Family Applications (2)

Application Number Title Priority Date Filing Date
AT97952407T ATE253903T1 (de) 1996-12-11 1997-12-11 Methoden und pharmazeutische zusammenstellungen zur wachstumsverhinderung von tumorzellen enthaltend einen ppar-gamma agonisten und einen map kinase inhibitor
AT03078539T ATE462433T1 (de) 1996-12-11 1997-12-11 Methoden und pharmazeutische zusammensetzungen zur inhibition des tumorwachstums

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT03078539T ATE462433T1 (de) 1996-12-11 1997-12-11 Methoden und pharmazeutische zusammensetzungen zur inhibition des tumorwachstums

Country Status (8)

Country Link
US (1) US7635708B2 (https=)
EP (2) EP1410799B1 (https=)
JP (2) JP4549443B2 (https=)
AT (2) ATE253903T1 (https=)
AU (1) AU5601898A (https=)
CA (1) CA2274756C (https=)
DE (2) DE69739828D1 (https=)
WO (1) WO1998025598A2 (https=)

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US6756399B2 (en) 2001-06-29 2004-06-29 The United States Of America As Represented By The Department Of Health And Human Services Use of lipoxygenase inhibitors and PPAR ligands as anti-cancer therapeutic and intervention agents
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US8309562B2 (en) 2003-07-03 2012-11-13 Myrexis, Inc. Compounds and therapeutical use thereof
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CN107073079A (zh) * 2014-09-08 2017-08-18 达纳－法伯癌症研究所公司 包括给予PPAR‑γ激动剂的治疗癌症的方法
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US10960013B2 (en) * 2016-03-04 2021-03-30 East Carolina University J-series prostaglandin-ethanolamides as novel therapeutics for skin and/or oral disorders
KR20180121983A (ko) 2016-03-10 2018-11-09 아이오 테라퓨틱스, 인크. Rxr 작용제 및 갑상선 호르몬의 조합을 사용한 근육 질환의 치료
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Also Published As

Publication number Publication date
JP4549443B2 (ja) 2010-09-22
WO1998025598A2 (en) 1998-06-18
JP4550133B2 (ja) 2010-09-22
ATE462433T1 (de) 2010-04-15
EP0948324A2 (en) 1999-10-13
CA2274756C (en) 2007-03-13
EP1410799B1 (en) 2010-03-31
DE69726182D1 (de) 2003-12-18
EP1410799A1 (en) 2004-04-21
US20030144330A1 (en) 2003-07-31
WO1998025598A3 (en) 1998-07-30
EP0948324B1 (en) 2003-11-12
AU5601898A (en) 1998-07-03
DE69726182T2 (de) 2004-08-12
DE69739828D1 (de) 2010-05-12
JP2001510462A (ja) 2001-07-31
JP2009063566A (ja) 2009-03-26
US7635708B2 (en) 2009-12-22
CA2274756A1 (en) 1998-06-18

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