JP4489351B2 - ヒト免疫不全ウイルスに対するモノクローナル抗体およびその用途 - Google Patents

ヒト免疫不全ウイルスに対するモノクローナル抗体およびその用途 Download PDF

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Publication number
JP4489351B2
JP4489351B2 JP2002564544A JP2002564544A JP4489351B2 JP 4489351 B2 JP4489351 B2 JP 4489351B2 JP 2002564544 A JP2002564544 A JP 2002564544A JP 2002564544 A JP2002564544 A JP 2002564544A JP 4489351 B2 JP4489351 B2 JP 4489351B2
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JP
Japan
Prior art keywords
hiv
antigen
antibody
test sample
signal
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Expired - Lifetime
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JP2002564544A
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English (en)
Japanese (ja)
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JP2004536568A (ja
JP2004536568A5 (https=
Inventor
ロウ，シヨン・シー
ハント，ジエフリー・シー
コンラス，ジヨン・ジー
チウ，シヤオシン
シエフエル，ジエイムズ・ダブリユ
タイナー，ジヨーン・デイー
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Abbott Laboratories
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Abbott Laboratories
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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—RNA viruses
    • C07K16/112—Retroviridae (F), e.g. leukemia viruses
    • C07K16/114—Lentivirus (G), e.g. human immunodeficiency virus [HIV], feline immunodeficiency virus [FIV] or simian immunodeficiency virus [SIV]
    • C07K16/1143—Gag-pol proteins, e.g. p17or p24
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C07K14/08—RNA viruses
    • C07K14/15—Retroviridae, e.g. bovine leukaemia virus, feline leukaemia virus human T-cell leukaemia-lymphoma virus
    • C07K14/155—Lentiviridae, e.g. human immunodeficiency virus [HIV], visna-maedi virus or equine infectious anaemia virus
    • C07K14/16—HIV-1 ; HIV-2
    • C07K14/161—HIV-1 ; HIV-2 gag-pol, e.g. p55, p24/25, p17/18, p7, p6, p66/68, p51/52, p31/34, p32, p40
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983—Viruses
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16211—Human Immunodeficiency Virus, HIV concerning HIV gagpol
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16211—Human Immunodeficiency Virus, HIV concerning HIV gagpol
    • C12N2740/16222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Oncology (AREA)
  • AIDS & HIV (AREA)
  • Communicable Diseases (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
JP2002564544A 2000-12-06 2001-12-05 ヒト免疫不全ウイルスに対するモノクローナル抗体およびその用途 Expired - Lifetime JP4489351B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/731,126 US6818392B2 (en) 2000-12-06 2000-12-06 Monoclonal antibodies to human immunodeficiency virus and uses thereof
PCT/US2001/043179 WO2002064615A2 (en) 2000-12-06 2001-12-05 Monoclonal antibodies to human immunodeficiency virus and uses thereof

Publications (3)

Publication Number Publication Date
JP2004536568A JP2004536568A (ja) 2004-12-09
JP2004536568A5 JP2004536568A5 (https=) 2009-01-15
JP4489351B2 true JP4489351B2 (ja) 2010-06-23

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JP2002564544A Expired - Lifetime JP4489351B2 (ja) 2000-12-06 2001-12-05 ヒト免疫不全ウイルスに対するモノクローナル抗体およびその用途

Country Status (6)

Country Link
US (10) US6818392B2 (https=)
EP (2) EP2336175B1 (https=)
JP (1) JP4489351B2 (https=)
CA (1) CA2431321C (https=)
ES (1) ES2619370T3 (https=)
WO (1) WO2002064615A2 (https=)

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Also Published As

Publication number Publication date
US20050031624A1 (en) 2005-02-10
US7897332B2 (en) 2011-03-01
WO2002064615A3 (en) 2003-04-17
US20130130233A1 (en) 2013-05-23
US20050053925A1 (en) 2005-03-10
EP2336175B1 (en) 2017-01-18
CA2431321C (en) 2012-05-29
US20020106636A1 (en) 2002-08-08
US6818392B2 (en) 2004-11-16
US7531641B2 (en) 2009-05-12
EP2336175A1 (en) 2011-06-22
US20050053924A1 (en) 2005-03-10
EP1341820A2 (en) 2003-09-10
US7528238B2 (en) 2009-05-05
US9115189B2 (en) 2015-08-25
US7531642B2 (en) 2009-05-12
US7531639B2 (en) 2009-05-12
US20040101831A1 (en) 2004-05-27
JP2004536568A (ja) 2004-12-09
US20050058994A1 (en) 2005-03-17
CA2431321A1 (en) 2002-08-22
US20050053610A1 (en) 2005-03-10
US7531638B2 (en) 2009-05-12
ES2619370T3 (es) 2017-06-26
US20120100632A1 (en) 2012-04-26
US7531640B2 (en) 2009-05-12
US20050025772A1 (en) 2005-02-03
WO2002064615A2 (en) 2002-08-22

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