JP4485208B2 - 流体ポンプ - Google Patents
流体ポンプ Download PDFInfo
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- JP4485208B2 JP4485208B2 JP2003570904A JP2003570904A JP4485208B2 JP 4485208 B2 JP4485208 B2 JP 4485208B2 JP 2003570904 A JP2003570904 A JP 2003570904A JP 2003570904 A JP2003570904 A JP 2003570904A JP 4485208 B2 JP4485208 B2 JP 4485208B2
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
- A61M60/80—Constructional details other than related to driving
- A61M60/855—Constructional details other than related to driving of implantable pumps or pumping devices
- A61M60/89—Valves
- A61M60/894—Passive valves, i.e. valves actuated by the blood
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
- A61M60/10—Location thereof with respect to the patient's body
- A61M60/104—Extracorporeal pumps, i.e. the blood being pumped outside the patient's body
- A61M60/109—Extracorporeal pumps, i.e. the blood being pumped outside the patient's body incorporated within extracorporeal blood circuits or systems
- A61M60/113—Extracorporeal pumps, i.e. the blood being pumped outside the patient's body incorporated within extracorporeal blood circuits or systems in other functional devices, e.g. dialysers or heart-lung machines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
- A61M60/10—Location thereof with respect to the patient's body
- A61M60/104—Extracorporeal pumps, i.e. the blood being pumped outside the patient's body
- A61M60/117—Extracorporeal pumps, i.e. the blood being pumped outside the patient's body for assisting the heart, e.g. transcutaneous or external ventricular assist devices
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
- A61M60/10—Location thereof with respect to the patient's body
- A61M60/122—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body
- A61M60/126—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body implantable via, into, inside, in line, branching on, or around a blood vessel
- A61M60/148—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body implantable via, into, inside, in line, branching on, or around a blood vessel in line with a blood vessel using resection or like techniques, e.g. permanent endovascular heart assist devices
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
- A61M60/30—Medical purposes thereof other than the enhancement of the cardiac output
- A61M60/36—Medical purposes thereof other than the enhancement of the cardiac output for specific blood treatment; for specific therapy
- A61M60/38—Blood oxygenation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
- A61M60/40—Details relating to driving
- A61M60/424—Details relating to driving for positive displacement blood pumps
- A61M60/427—Details relating to driving for positive displacement blood pumps the force acting on the blood contacting member being hydraulic or pneumatic
- A61M60/43—Details relating to driving for positive displacement blood pumps the force acting on the blood contacting member being hydraulic or pneumatic using vacuum at the blood pump, e.g. to accelerate filling
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
- A61M60/40—Details relating to driving
- A61M60/424—Details relating to driving for positive displacement blood pumps
- A61M60/457—Details relating to driving for positive displacement blood pumps the force acting on the blood contacting member being magnetic
- A61M60/462—Electromagnetic force
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2230/00—Measuring parameters of the user
- A61M2230/04—Heartbeat characteristics, e.g. ECG, blood pressure modulation
Description
Claims (28)
- 少なくとも1個のリニア電磁モータと、
前記リニア電磁モータに連結され、それにより直線方向に移動するように構成された少なくとも1個のポンプ駆動ヘッドと、
流体を収容する変形可能な流体室を形成し、前記ポンプ駆動ヘッドの動きに応じる少なくとも1個の流体ハウジングと、
前記リニア電磁モータに連結されたコントローラと、
を備え、
前記流体ハウジングは、第1の出入口と少なくとも1個の第2の出入口を備え、前記第1の出入口が前記流体室内に前記流体を流すとともに、前記第2の出入口が前記流体室から外に前記流体を流すことができ、前記ポンプ駆動ヘッドが変形可能な前記流体室を変形して前記流体室内に圧力差を生じさせ、それによって前記流体室の容積を変更し、前記流体室の中または外へ、それぞれ、第1及び第2の出入り口を介して前記流体を圧送し、
前記コントローラは、前記リニア電磁モータに予め決められた電流波形の電流を供給し、
この電流波形は、前記コントローラにより設定された自然の心臓の収縮期を模した正の最大電流値、自然の心臓の拡張期を模した負の最大電流値、周期、及び、前記負の最大電流値に対する前記正の最大電流値の値に基づいて形成されるものであることを特徴とする、流体を圧送するためのポンプ。 - 前記リニア電磁モータが、
空隙を形成するコアと、前記空隙近くの前記コアの少なくとも一部の周りに配置された少なくとも1個のコイルと、前記空隙内に配置され前記直線方向に移動可能である磁石部材とを備えていることを特徴とする請求項1記載のポンプ。 - 前記ポンプ駆動ヘッドが前記磁石部材に連結されていることを特徴とする請求項2記載のポンプ。
- 少なくとも第1、第2、第3および第4のポンプと、
これらのポンプに連結される少なくとも第1と第2のモータと、
前記第1と第2のモータに連結される少なくとも1個のポンプ駆動ヘッドと、
心停止液を混合する合流部と、
第1、第2、第3および第4の流体ハウジングとを備え、
前記流体が血液を含み、前記の第1のポンプが、静脈容器から熱交換器と酸素供給器に前記血液を圧送し、前記の第2のポンプが、前記酸素供給器から前記第2のポンプの前記出口近くに配置された動脈フィルタを経て患者の動脈系に前記血液を圧送し、前記第3のポンプが、前記第2のポンプの前記出口から前記動脈血液の一部を前記合流部に圧送して、前記動脈血液の一部を、第4のポンプから圧送される心停止液と混合し、前記第3と第4のポンプが、血液と心停止液の前記混合物を、前記合流部と、前記合流部近くに配置された第2の熱交換器を経て、前記動脈系に圧送することを特徴とすることを特徴とする、前記ポンプが請求項1記載のポンプで構成されるポンプ。 - 前記ポンプが第1と第2の流体ハウジングと、それぞれ前記モータの第1と第2の端部に連結された第1と第2のポンプ駆動ヘッドとを備え、前記の第1と第2のポンプ駆動ヘッドが互いに位相を180°外して動くことを特徴とする、請求項1記載のポンプ。
- 前記流体が血液を含み、前記ポンプが拍動バランス流を生じる心臓ポンプを備え、前記心臓ポンプがコントローラを備え、前記ポンプ駆動ヘッドが前記流体室と相対的に予め定めた位置に達するまで、前記コントローラが前記モータに電流を供給し、それによって予め定めた量の血液が前記流体室内に移動し、使用者調節可能な予め定めた血液圧力が患者の動脈系内に発生することを特徴とする、請求項1記載のポンプ。
- 前記ポンプが管によって前記の変形可能な流体ハウジングに連結されたアクチュエータハウジングを備え、前記アクチュエータハウジングが作動流体を有するアクチュエータ室と、前記ポンプ駆動ヘッドの近くの変形可能な壁を形成し、前記流体ハウジングが圧送すべき前記流体を収容し、かつ入口と出口を備え、前記ポンプ駆動ヘッドが前記アクチュエータ室の変形可能な壁を変形して、前記作動流体を前記管に流し、そして前記の変形可能な流体ハウジングを変形し、それによって前記流体ハウジング内に圧力差を生じ、この圧力差が圧送すべき前記流体を前記入口と出口に流すことを特徴とする、請求項1記載のポンプ。
- 少なくとも第1と第2のモータと、
第1、第2、第3および第4のポンプを備え、更に、
前記の少なくとも第と第2のモータに連結された少なくとも1個のポンプ駆動ヘッドと、
心停止液容器と、この心停止液容器からの心停止液を血液と混合する合流部と、
少なくとも1個のポンプ駆動ヘッドに応答する第1、第2、第3および第4の変形可能な流体ハウジングとを備え、
この流体ハウジングが、それぞれ、血液を含む流体を収容する流体室を形成し、前記流体ハウジングが入口と出口を備え、
この入口と出口が前記流体を前記流体ハウジングの中または外へ流すことができ、
各々の入口と出口が第1と少なくとも第2の出入り口であり、第1の出入り口において前記流体を前記流体室に流すことができ、第2の出入り口において前記流体を流体室から流すことができ、
前記ポンプ駆動ヘッドが前記の変形可能な流体室を変形し、前記変形可能な流体室内に圧力差を生じさせるように構成され、
前記第1のポンプが前記の血液を静脈容器から熱交換器と酸素供給器に圧送し、前記第2のポンプが前記血液を前記酸素供給器から前記第2のポンプの前記出口の近くに配置された動脈フィルタを経て患者の動脈系に圧送し、前記第3のポンプが前記の動脈血液の一部を、前記の第2のポンプの出口から前記合流部に圧送し、前記第4のポンプが決められた量の心停止液を心停止液容器から前記合流部に圧送して前記動脈血液の一部を心停止液が混合され、前記第3と第4のポンプが、血液と心停止液の前記混合物を、前記合流部と、前記合流部の近くに配置された第2の熱交換器を経て、前記動脈系に圧送することを特徴とする、前記ポンプが請求項1記載のポンプで構成される、人工心肺システム。 - 前記リニア電磁モータが、
空隙を形成するコアと、前記空隙近くの前記コアの少なくとも一部の周りに配置された少なくとも1個のコイルと、前記空隙内に配置され前記直線方向に移動可能である磁石部材とを備えていることを特徴とする、請求項8記載の人工心肺システム。 - 前記ポンプ駆動ヘッドが前記磁石部材に連結されていることを特徴とする、請求項9記載の人工心肺システム。
- 第1と第2のポンプ駆動ヘッドが前記の第1のモータの第1と第2の端部に連結され、互いに位相を180°外して運動し、前記の第1と第2のポンプ駆動ヘッドがそれぞれ、前記の第1と第2のポンプの前記の第1と第2の変形可能な流体ハウジング内で圧力差を交互に生じることを特徴とする、請求項8記載の人工心肺システム。
- 前記ポンプが更にコントローラを備え、前記ポンプ駆動ヘッドが変形可能な前記各流体室と相対的に予め定めた位置に達するまで、前記コントローラが前記モータに電流を供給し、それによって予め定めた量が変形可能な前記流体室内に移動し、使用者調節可能な予め定めた血液圧力が患者の動脈系内に発生することを特徴とする、請求項8記載の人工心肺システム。
- 前記の各ポンプが管によって前記の変形可能な流体ハウジングに連結されたアクチュエータハウジングを備え、前記各アクチュエータハウジングが作動流体を有するアクチュエータ室と、前記ポンプ駆動ヘッドの近くの変形可能な壁を形成し、前記ポンプ駆動ヘッドが前記アクチュエータ室の変形可能な壁を変形して、前記作動流体を前記管に流し、そして前記の変形可能な流体ハウジングを変形し、それによって変形可能な前記流体ハウジング内に圧力差を生じ、この圧力差が圧送すべき前記流体を前記入口と出口に流すことを特徴とする、請求項8記載の人工心肺システム。
- 請求項1記載のポンプを備え、生理的な拍動流を生じる、最小侵襲性の体外の補助人工心臓装置(VAD)であって、このVADが前記ポンプと流体室を備え、この流体室が弁を備えていない少なくとも1つの出入口を有し、前記の最小侵襲性の体外のVADが経皮カニューレを用いて患者に接続され、前記ポンプのタイミングが前記患者のEKGを読み取ることによって制御され、それによって自然の心臓の収縮期の間、前記ポンプが前記流体室を血液で満たし、前記の患者の動脈系にわずかな真空を作用させ、それによって後負荷を減少させかつ心拍出量を増大させ、自然の心臓の拡張期の間、前記ポンプが前記流体室から血液を排出し、前記患者の動脈系の前記圧力を増大させることを特徴とする補助人工心臓装置。
- 前記リニア電磁モータが、空隙を形成するコアと、前記空隙の近くの前記コアの少なくとも一部の周りに配置された少なくとも1個のコイルと、前記空隙内に配置され前記直線方向に移動可能である磁石部材とを備えていることを特徴とする、請求項14記載の補助人工心臓装置。
- 前記ポンプ駆動ヘッドが前記磁石部材に連結されていることを特徴とする、請求項15記載の補助人工心臓装置。
- 請求項1記載のポンプを用いる方法であって、
流体室と、弁を備えていない一つの単一出入口とを有する前記ポンプを備えた補助人工心臓装置(VAD)を、前記の弁を備えていない単一出入口を介して、患者の動脈系に接続し、
自然の心臓収縮期の間、前記の弁を備えていない単一出入口から、前記流体室に血液を充填し、
自然の心臓拡張期の間、前記の弁を備えていない単一出入口を経て、前記流体室から前記血液を排出し、前記の流体室の充填作用が患者の動脈系にわずかな真空を生じ、それによって後負荷を減少し、心拍出量を増大させ、前記の流体室を排出する前記作用が、患者の前記動脈系の圧力を増大させる心臓を補助する方法。 - 前記のVADと患者の動脈系を接続する前記作用が、経皮カミューレを用いた、前記のVADと前記患者の動脈系の接続を含んでいることを特徴とする、請求項17記載の方法。
- 前記の流体室の前記の充填と排出作用が、前記患者のEKGを読み取ることによって制御されることを特徴とする、請求項17記載の方法。
- 請求項1記載のポンプを用いることにより、室内の血液を移動させるモータを備えた心臓ポンプを作動させる方法であって、
この方法が
前記ポンプによって移動させられる血液の量を指定し、
ポンプ拡張期の間前記室内で維持すべき拡張圧力を指定し、
前記血液の量が前記室から移動するまで、前記拡張圧力を維持するために前記モータに拡張電流を供給し、
ポンプ収縮期の間前記室内で維持すべき収縮圧力を指定し、
前記血液の量が前記室から移動するまで、前記収縮圧力を維持するために前記モータに収縮電流を供給することを特徴とする方法。 - 前記モータがポンプ駆動ヘッドに連結されたリニア電磁モータであり、それによって前記ポンプ駆動ヘッドが前記血液量を移動させるために直線方向に移動可能であることを特徴とする、請求項20記載の方法。
- 電気機械的および生理的な血液流れを生じさせるために、請求項1記載のポンプを用いるシステムにおいて、
電気機械的なポンプ装置が、
コイルと動く部材を備えた少なくとも1個のリニアモータと、
前記リニアモータの前記の動く部材に連結された少なくとも1個の血液ポンプとを備え、前記リニアモータの前記の動く部材に連結されているときに前記血液ポンプが生理系な血液流れを生じることを特徴とするシステム。 - 前記第1及び第2の出入口がそれを通る前記流体の流れを制御するために、それぞれ弁を備えていることを特徴とする、請求項1記載のポンプ。
- 前記弁がボール弁を備え、このボール弁がボール弁保持器領域と、弁座と、前記ボール弁保持器領域内に配置されたオクルダーボールを備え、前記ポンプ駆動ヘッドが変形可能な前記流体室を変形し、前記流体室内に圧力差を生じ、それによって前記流体室の容積を変更し、前記流体室の中または外へ前記流体を圧送し、前記圧力差が前記オクルダーボールを前記ボール弁保持器領域内の第1の位置から前記ボール弁保持器領域内の第2の位置に移動させ、第1の位置からの移動によって、流体が前記出入口を通過できなくなり、第2の位置への移動によって、前記オクルダーボールが前記弁保持器に抗して押され、前記流体が前記のオクルダーボールの周りに環状に移動し、第1の位置から第2の位置への前記オクルダーボールの前記移動が、前記流体の流れ内にわずかな逆戻りを生じることを特徴とする、請求項23記載のポンプ。
- 前記コントローラが生理的な拍動流を生成するための電流波形状を生じることを特徴とする、請求項1記載のポンプ。
- 前記コントローラが使用者によってプログラミング可能な拍動流を生成するための電流波形状を生じることを特徴とする、請求項1記載のポンプ。
- 前記コントローラが任意の流れを生成するための電流波形状を生じることを特徴とする、請求項1記載のポンプ。
- 前記のポンプが管によって前記の変形可能な流体ハウジングに連結されたアクチュエータハウジングを備え、前記アクチュエータハウジングが作動流体を有するアクチュエータ室と、前記ポンプ駆動ヘッドの近くの変形可能な壁を形成し、前記流体ハウジングが圧送すべき前記液体を収容し、かつ入口と出口を備え、前記ポンプ駆動ヘッドが前記アクチュエータ室の変形可能な壁を変形して、前記作動流体を前記管に流し、そして前記の変形可能な流体ハウジングを変形し、それによって前記流体ハウジング内に圧力差を生じ、この圧力差が圧送すべき前記流体を前記入口と出口に流すことを特徴とする、請求項1記載のポンプ。
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JP2005518491A JP2005518491A (ja) | 2005-06-23 |
JP2005518491A5 JP2005518491A5 (ja) | 2006-04-20 |
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JP2003570904A Expired - Fee Related JP4485208B2 (ja) | 2002-02-21 | 2003-02-21 | 流体ポンプ |
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EP (2) | EP2298370B1 (ja) |
JP (1) | JP4485208B2 (ja) |
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CA (1) | CA2476473C (ja) |
DK (1) | DK2298370T3 (ja) |
WO (1) | WO2003072161A2 (ja) |
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-
2003
- 2003-02-21 AU AU2003215342A patent/AU2003215342A1/en not_active Abandoned
- 2003-02-21 JP JP2003570904A patent/JP4485208B2/ja not_active Expired - Fee Related
- 2003-02-21 EP EP10182501.6A patent/EP2298370B1/en not_active Expired - Lifetime
- 2003-02-21 CA CA2476473A patent/CA2476473C/en not_active Expired - Lifetime
- 2003-02-21 DK DK10182501.6T patent/DK2298370T3/da active
- 2003-02-21 WO PCT/US2003/005179 patent/WO2003072161A2/en active Application Filing
- 2003-02-21 EP EP03711163A patent/EP1503821A4/en not_active Ceased
- 2003-02-21 US US10/372,023 patent/US7238165B2/en not_active Expired - Lifetime
-
2007
- 2007-05-22 US US11/751,954 patent/US7850593B2/en active Active
Also Published As
Publication number | Publication date |
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US20070255089A1 (en) | 2007-11-01 |
EP1503821A4 (en) | 2007-05-30 |
DK2298370T3 (da) | 2014-01-27 |
US20040015042A1 (en) | 2004-01-22 |
US7850593B2 (en) | 2010-12-14 |
WO2003072161A3 (en) | 2004-11-18 |
CA2476473A1 (en) | 2003-09-04 |
AU2003215342A1 (en) | 2003-09-09 |
EP2298370A1 (en) | 2011-03-23 |
EP1503821A2 (en) | 2005-02-09 |
CA2476473C (en) | 2013-02-19 |
JP2005518491A (ja) | 2005-06-23 |
US7238165B2 (en) | 2007-07-03 |
EP2298370B1 (en) | 2013-10-30 |
WO2003072161A2 (en) | 2003-09-04 |
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