JP4475487B2 - Ｈｉｖの核局在化阻害剤 - Google Patents

Ｈｉｖの核局在化阻害剤 Download PDF

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Publication number
JP4475487B2
JP4475487B2 JP2000509697A JP2000509697A JP4475487B2 JP 4475487 B2 JP4475487 B2 JP 4475487B2 JP 2000509697 A JP2000509697 A JP 2000509697A JP 2000509697 A JP2000509697 A JP 2000509697A JP 4475487 B2 JP4475487 B2 JP 4475487B2
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JP
Japan
Prior art keywords
compound
hiv
branched
independently
linear
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Expired - Fee Related
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JP2000509697A
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English (en)
Japanese (ja)
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JP2001515069A (ja
JP2001515069A5 (https=
Inventor
パン，センリアン
ブクリンスキ，マイケル
ケー． ハファー，オマー
Original Assignee
サイトカイン ファーマサイエンシズ インコーポレイティド
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Publication of JP2001515069A5 publication Critical patent/JP2001515069A5/ja
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/47—One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48—Two nitrogen atoms

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • AIDS & HIV (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
JP2000509697A 1997-08-15 1998-08-13 Ｈｉｖの核局在化阻害剤 Expired - Fee Related JP4475487B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/912,076 1997-08-15
US08/912,076 US5808068A (en) 1997-08-15 1997-08-15 HIV nuclear localization inhibitors
PCT/US1998/016814 WO1999009014A1 (en) 1997-08-15 1998-08-13 Hiv nuclear localization inhibitors

Publications (3)

Publication Number Publication Date
JP2001515069A JP2001515069A (ja) 2001-09-18
JP2001515069A5 JP2001515069A5 (https=) 2006-01-05
JP4475487B2 true JP4475487B2 (ja) 2010-06-09

Family

ID=25431342

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2000509697A Expired - Fee Related JP4475487B2 (ja) 1997-08-15 1998-08-13 Ｈｉｖの核局在化阻害剤

Country Status (8)

Country Link
US (1) US5808068A (https=)
EP (1) EP1012146B1 (https=)
JP (1) JP4475487B2 (https=)
AT (1) ATE245983T1 (https=)
AU (1) AU758464B2 (https=)
CA (1) CA2300424C (https=)
DE (1) DE69816835T2 (https=)
WO (1) WO1999009014A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6297253B1 (en) * 1996-10-15 2001-10-02 The Picower Institute For Medical Research Compounds and methods of use to treat infectious diseases
CA2686618A1 (en) * 2003-07-17 2005-01-17 At&T Corp. Method and apparatus for windowing in entropy encoding
US20050203150A1 (en) * 2004-03-09 2005-09-15 Haffar Omar K. Compounds, compositions and methods for inhibiting or treating HIV-1

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0673022A (ja) * 1992-08-27 1994-03-15 Kumiai Chem Ind Co Ltd ピリミジンまたはトリアジン誘導体及び除草剤

Also Published As

Publication number Publication date
CA2300424C (en) 2009-04-07
WO1999009014A1 (en) 1999-02-25
EP1012146A1 (en) 2000-06-28
EP1012146A4 (en) 2002-12-04
EP1012146B1 (en) 2003-07-30
DE69816835T2 (de) 2004-04-22
DE69816835D1 (de) 2003-09-04
ATE245983T1 (de) 2003-08-15
JP2001515069A (ja) 2001-09-18
US5808068A (en) 1998-09-15
AU758464B2 (en) 2003-03-20
AU8905498A (en) 1999-03-08
CA2300424A1 (en) 1999-02-25

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