ATE245983T1 - Inhibitoren der nuklearen lokalisierung von hiv - Google Patents

Inhibitoren der nuklearen lokalisierung von hiv

Info

Publication number
ATE245983T1
ATE245983T1 AT98940874T AT98940874T ATE245983T1 AT E245983 T1 ATE245983 T1 AT E245983T1 AT 98940874 T AT98940874 T AT 98940874T AT 98940874 T AT98940874 T AT 98940874T AT E245983 T1 ATE245983 T1 AT E245983T1
Authority
AT
Austria
Prior art keywords
hiv
nuclear localization
inhibitors
genus
compounds
Prior art date
Application number
AT98940874T
Other languages
English (en)
Inventor
Senliang Pan
Michael Bukrinsky
Omar K Haffar
Original Assignee
Picower Inst Med Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Picower Inst Med Res filed Critical Picower Inst Med Res
Application granted granted Critical
Publication of ATE245983T1 publication Critical patent/ATE245983T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/47—One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48—Two nitrogen atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • AIDS & HIV (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT98940874T 1997-08-15 1998-08-13 Inhibitoren der nuklearen lokalisierung von hiv ATE245983T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/912,076 US5808068A (en) 1997-08-15 1997-08-15 HIV nuclear localization inhibitors
PCT/US1998/016814 WO1999009014A1 (en) 1997-08-15 1998-08-13 Hiv nuclear localization inhibitors

Publications (1)

Publication Number Publication Date
ATE245983T1 true ATE245983T1 (de) 2003-08-15

Family

ID=25431342

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98940874T ATE245983T1 (de) 1997-08-15 1998-08-13 Inhibitoren der nuklearen lokalisierung von hiv

Country Status (8)

Country Link
US (1) US5808068A (de)
EP (1) EP1012146B1 (de)
JP (1) JP4475487B2 (de)
AT (1) ATE245983T1 (de)
AU (1) AU758464B2 (de)
CA (1) CA2300424C (de)
DE (1) DE69816835T2 (de)
WO (1) WO1999009014A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6297253B1 (en) * 1996-10-15 2001-10-02 The Picower Institute For Medical Research Compounds and methods of use to treat infectious diseases
CA2475189C (en) * 2003-07-17 2009-10-06 At&T Corp. Method and apparatus for window matching in delta compressors
US20050203150A1 (en) * 2004-03-09 2005-09-15 Haffar Omar K. Compounds, compositions and methods for inhibiting or treating HIV-1

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0673022A (ja) * 1992-08-27 1994-03-15 Kumiai Chem Ind Co Ltd ピリミジンまたはトリアジン誘導体及び除草剤

Also Published As

Publication number Publication date
AU8905498A (en) 1999-03-08
JP2001515069A (ja) 2001-09-18
WO1999009014A1 (en) 1999-02-25
EP1012146B1 (de) 2003-07-30
EP1012146A1 (de) 2000-06-28
DE69816835T2 (de) 2004-04-22
CA2300424C (en) 2009-04-07
JP4475487B2 (ja) 2010-06-09
CA2300424A1 (en) 1999-02-25
AU758464B2 (en) 2003-03-20
US5808068A (en) 1998-09-15
EP1012146A4 (de) 2002-12-04
DE69816835D1 (de) 2003-09-04

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties