JP4414138B2 - 蛍光染料を通した分子のエピトープの免疫検出及び分子の相互作用の検出のための方法 - Google Patents
蛍光染料を通した分子のエピトープの免疫検出及び分子の相互作用の検出のための方法 Download PDFInfo
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1002—Tetrapeptides with the first amino acid being neutral
- C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
- C07K5/1013—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing O or S as heteroatoms, e.g. Cys, Ser
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/32—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1019—Tetrapeptides with the first amino acid being basic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/531—Production of immunochemical test materials
- G01N33/532—Production of labelled immunochemicals
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6854—Immunoglobulins
- G01N33/6857—Antibody fragments
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6878—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids in epitope analysis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/32—Fusion polypeptide fusions with soluble part of a cell surface receptor, "decoy receptors"
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
- G01N2500/04—Screening involving studying the effect of compounds C directly on molecule A (e.g. C are potential ligands for a receptor A, or potential substrates for an enzyme A)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Hematology (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Food Science & Technology (AREA)
- Microbiology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Cell Biology (AREA)
- Analytical Chemistry (AREA)
- Oncology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/783,896 US7045286B2 (en) | 2000-07-25 | 2001-02-15 | Methods of detecting molecules expressing selected epitopes via fluorescent dyes |
| US09/977,716 US7524628B2 (en) | 2000-07-25 | 2001-10-15 | Method for detecting molecules expressing a selected epitope via fluorescent dyes |
| PCT/US2002/003640 WO2002066980A1 (en) | 2001-02-15 | 2002-02-08 | Methods for immuno-detection of epitopes on molecules and for detection of interactions of molecules via fluorescent dyes |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2004532393A JP2004532393A (ja) | 2004-10-21 |
| JP2004532393A5 JP2004532393A5 (enExample) | 2005-12-22 |
| JP4414138B2 true JP4414138B2 (ja) | 2010-02-10 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002566655A Expired - Fee Related JP4414138B2 (ja) | 2001-02-15 | 2002-02-08 | 蛍光染料を通した分子のエピトープの免疫検出及び分子の相互作用の検出のための方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US7524628B2 (enExample) |
| EP (2) | EP1366363A4 (enExample) |
| JP (1) | JP4414138B2 (enExample) |
| AU (1) | AU2002243878B8 (enExample) |
| CA (1) | CA2439235A1 (enExample) |
| WO (1) | WO2002066980A1 (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7176037B2 (en) * | 2000-07-13 | 2007-02-13 | The Scripps Research Institute | Labeled peptides, proteins and antibodies and processes and intermediates useful for their preparation |
| US6951947B2 (en) * | 2000-07-13 | 2005-10-04 | The Scripps Research Institute | Labeled peptides, proteins and antibodies and processes and intermediates useful for their preparation |
| US20050069962A1 (en) | 2001-10-12 | 2005-03-31 | Archer Robert M | Antibody complexes and methods for immunolabeling |
| US8323903B2 (en) | 2001-10-12 | 2012-12-04 | Life Technologies Corporation | Antibody complexes and methods for immunolabeling |
| EP1513543B1 (en) | 2002-05-23 | 2010-10-06 | The Trustees of The University of Pennsylvania | Fas peptide mimetics and uses thereof |
| CN101410530B (zh) * | 2003-04-18 | 2013-03-27 | 贝克顿·迪金森公司 | 免疫-扩增 |
| WO2005054514A1 (en) * | 2003-12-02 | 2005-06-16 | Agency For Science, Technology And Research | Immuno-amplification rna assay |
| US7906624B2 (en) * | 2004-02-20 | 2011-03-15 | The Trustees Of The University Of Pennsylvania | Binding peptidomimetics and uses of the same |
| US7842456B2 (en) * | 2004-02-20 | 2010-11-30 | The Trustees Of The University Of Pennsylvania | Reagents, kits and methods for immunodetection of epitopes on molecules |
| WO2005088308A2 (en) * | 2004-03-12 | 2005-09-22 | The Scripps Research Institute | Fluorescent signal emitting live cell biosensor molecules and dyes for detection and quantification of protein activities |
| WO2010085548A2 (en) * | 2009-01-22 | 2010-07-29 | Li-Cor, Inc. | Single molecule proteomics with dynamic probes |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2596413B1 (fr) * | 1986-03-27 | 1988-06-10 | Merieux Inst | Nouveaux milieux de culture de bacteries appartenant au genre bordetella, contenant des derives etherifies de polymeres de d-glucose, et leur application |
| US5627027A (en) * | 1986-04-18 | 1997-05-06 | Carnegie Mellon University | Cyanine dyes as labeling reagents for detection of biological and other materials by luminescence methods |
| US5631129A (en) * | 1988-12-05 | 1997-05-20 | The Salk Institute For Biological Studies | Target nucleic acid amplification/detection systems and methods for the use thereof |
| GB9206318D0 (en) | 1992-03-24 | 1992-05-06 | Cambridge Antibody Tech | Binding substances |
| US6172197B1 (en) | 1991-07-10 | 2001-01-09 | Medical Research Council | Methods for producing members of specific binding pairs |
| US5334702A (en) | 1991-03-25 | 1994-08-02 | University Of Illinois | Compositions which are immunologically crossreactive with antibodies and preparative methods therefor |
| US6225447B1 (en) | 1991-05-15 | 2001-05-01 | Cambridge Antibody Technology Ltd. | Methods for producing members of specific binding pairs |
| DE69230142T2 (de) | 1991-05-15 | 2000-03-09 | Cambridge Antibody Technology Ltd. | Verfahren zur herstellung von spezifischen bindungspaargliedern |
| US5665539A (en) * | 1991-07-12 | 1997-09-09 | The Regents Of The University Of California | Immuno-polymerase chain reaction system for antigen detection |
| JPH05149949A (ja) | 1991-11-26 | 1993-06-15 | Nisshin Flour Milling Co Ltd | 新規な微量物質測定法 |
| CA2135073C (en) * | 1992-05-06 | 2002-11-19 | Daniel L. Kacian | Nucleic acid sequence amplification method, composition and kit |
| US5985548A (en) * | 1993-02-04 | 1999-11-16 | E. I. Du Pont De Nemours And Company | Amplification of assay reporters by nucleic acid replication |
| US5879657A (en) | 1993-03-30 | 1999-03-09 | The Dupont Merck Pharmaceutical Company | Radiolabeled platelet GPIIb/IIIa receptor antagonists as imaging agents for the diagnosis of thromboembolic disorders |
| US5436134A (en) * | 1993-04-13 | 1995-07-25 | Molecular Probes, Inc. | Cyclic-substituted unsymmetrical cyanine dyes |
| AU6913394A (en) | 1993-05-13 | 1994-12-12 | United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Nucleic acid tagged immunoassay |
| US5663144A (en) | 1995-05-03 | 1997-09-02 | The Trustees Of The University Of Pennsylvania | Compounds that bind to p185 and methods of using the same |
| US5874226A (en) * | 1995-05-22 | 1999-02-23 | H. Lee Browne | In situ immunodetection of antigens |
| US5922553A (en) | 1996-11-21 | 1999-07-13 | Trustees Of The University Of Pennsylvania | Method of detecting protein by immuno RNA |
| US6248527B1 (en) * | 1998-10-21 | 2001-06-19 | Millennium Pharmaceuticals, Inc. | Method of detecting risk of type II diabetes based on mutations found in carboxypeptidase E |
| US6132997A (en) * | 1999-05-28 | 2000-10-17 | Agilent Technologies | Method for linear mRNA amplification |
| US7045286B2 (en) * | 2000-07-25 | 2006-05-16 | The Trustees Of The University Of Pennsylvania | Methods of detecting molecules expressing selected epitopes via fluorescent dyes |
| US6743592B1 (en) * | 2000-07-25 | 2004-06-01 | The Trustees Of The University Of Pennsylvania | Methods, systems and kits for immuno-detection of epitopes expressed on molecules |
-
2001
- 2001-10-15 US US09/977,716 patent/US7524628B2/en not_active Expired - Lifetime
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2002
- 2002-02-08 WO PCT/US2002/003640 patent/WO2002066980A1/en not_active Ceased
- 2002-02-08 CA CA002439235A patent/CA2439235A1/en not_active Abandoned
- 2002-02-08 EP EP02709394A patent/EP1366363A4/en not_active Ceased
- 2002-02-08 EP EP08008507A patent/EP2012124A3/en not_active Withdrawn
- 2002-02-08 JP JP2002566655A patent/JP4414138B2/ja not_active Expired - Fee Related
- 2002-02-08 AU AU2002243878A patent/AU2002243878B8/en not_active Ceased
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2009
- 2009-03-24 US US12/409,857 patent/US20090227468A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| JP2004532393A (ja) | 2004-10-21 |
| US7524628B2 (en) | 2009-04-28 |
| US20020094534A1 (en) | 2002-07-18 |
| EP2012124A3 (en) | 2009-06-10 |
| AU2002243878B2 (en) | 2007-10-18 |
| EP2012124A2 (en) | 2009-01-07 |
| EP1366363A1 (en) | 2003-12-03 |
| US20090227468A1 (en) | 2009-09-10 |
| CA2439235A1 (en) | 2002-08-29 |
| AU2002243878B8 (en) | 2008-03-20 |
| WO2002066980A1 (en) | 2002-08-29 |
| EP1366363A4 (en) | 2006-06-21 |
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