JP4411414B2 - 糖尿病性神経障害の治療に対する組成物及びその方法 - Google Patents

糖尿病性神経障害の治療に対する組成物及びその方法 Download PDF

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JP4411414B2
JP4411414B2 JP2002550919A JP2002550919A JP4411414B2 JP 4411414 B2 JP4411414 B2 JP 4411414B2 JP 2002550919 A JP2002550919 A JP 2002550919A JP 2002550919 A JP2002550919 A JP 2002550919A JP 4411414 B2 JP4411414 B2 JP 4411414B2
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composition
vitamin
antioxidants
diabetic neuropathy
aldose reductase
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JP2004516257A (ja
JP2004516257A5 (enExample
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ローゼンブルーム、リチャード、エー．
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ザ キグリー コーポレーション
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Priority claimed from US09/740,811 external-priority patent/US6555573B2/en
Priority claimed from US09/847,121 external-priority patent/US20020165207A1/en
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/385—Heterocyclic compounds having sulfur as a ring hetero atom having two or more sulfur atoms in the same ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/07—Retinol compounds, e.g. vitamin A
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A61K31/355—Tocopherols, e.g. vitamin E
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A61K31/593—9,10-Secocholestane derivatives, e.g. cholecalciferol, i.e. vitamin D3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/06—Free radical scavengers or antioxidants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/12—Antidiuretics, e.g. drugs for diabetes insipidus

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
JP2002550919A 2000-12-21 2001-12-19 糖尿病性神経障害の治療に対する組成物及びその方法 Expired - Fee Related JP4411414B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/740,811 US6555573B2 (en) 2000-12-21 2000-12-21 Method and composition for the topical treatment of diabetic neuropathy
US09/847,121 US20020165207A1 (en) 2001-05-02 2001-05-02 Compositions and methods for the treatment of diabetic neuropathy
PCT/US2001/049297 WO2002049575A2 (en) 2000-12-21 2001-12-19 Method and composition for the treatment of diabetic neuropathy

Publications (3)

Publication Number Publication Date
JP2004516257A JP2004516257A (ja) 2004-06-03
JP2004516257A5 JP2004516257A5 (enExample) 2005-05-26
JP4411414B2 true JP4411414B2 (ja) 2010-02-10

Family

ID=27113759

Family Applications (1)

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JP2002550919A Expired - Fee Related JP4411414B2 (ja) 2000-12-21 2001-12-19 糖尿病性神経障害の治療に対する組成物及びその方法

Country Status (11)

Country Link
EP (1) EP1351679B1 (enExample)
JP (1) JP4411414B2 (enExample)
AT (1) ATE456957T1 (enExample)
AU (2) AU2002231095B2 (enExample)
CA (1) CA2431079C (enExample)
DE (1) DE60141253D1 (enExample)
ES (1) ES2340363T3 (enExample)
IL (1) IL156549A0 (enExample)
MX (1) MXPA03005672A (enExample)
NZ (1) NZ526041A (enExample)
WO (1) WO2002049575A2 (enExample)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030105027A1 (en) * 2001-11-06 2003-06-05 Rosenbloom Richard A. Nutritional supplements and methods for prevention, reduction and treatment of radiation injury
MXPA04006039A (es) * 2001-12-19 2004-09-27 The Quigley Corp Metodo para el tratamiento de afecciones vasculares y neuronales perifericas.
FR2844716B1 (fr) * 2002-09-23 2008-11-21 Marcel Jacques Chicouri Nouvelles compositions pharmaceutiques destinees notamment a l'hygiene des pieds des diabetiques
DE10244282A1 (de) * 2002-09-23 2004-04-01 Merck Patent Gmbh Zubereitung mit antioxidanten Eigenschaften
AU2004253579B2 (en) 2003-07-01 2010-12-23 Biomol International L.P. Sirt1 modulators for manipulating cells/organism lifespan/stress response
US8017634B2 (en) * 2003-12-29 2011-09-13 President And Fellows Of Harvard College Compositions for treating obesity and insulin resistance disorders
US20050171027A1 (en) * 2003-12-29 2005-08-04 President And Fellows Of Harvard College Compositions for treating or preventing obesity and insulin resistance disorders
JP2006083138A (ja) * 2004-09-17 2006-03-30 Suntory Ltd アルドース還元酵素阻害剤
JP2006089399A (ja) * 2004-09-22 2006-04-06 Hajime Fukuda ２型糖尿病治療剤
JP2006298808A (ja) * 2005-04-19 2006-11-02 Hayashibara Biochem Lab Inc 痛覚刺激緩和剤
JP2006335752A (ja) * 2005-06-01 2006-12-14 Oriza Yuka Kk アルドース還元酵素阻害剤
WO2006138418A2 (en) 2005-06-14 2006-12-28 President And Fellows Of Harvard College Improvement of cognitive performance with sirtuin activators
EP1939166A1 (en) * 2006-12-19 2008-07-02 InterMed Discovery GmbH Plants extracts for use in brain modulation
DE102007029042A1 (de) * 2007-06-21 2008-12-24 Analyticon Discovery Gmbh Pharmazeutische Zusammensetzung mit einem Trihydroxychromenone-Derivate
JP4932776B2 (ja) * 2008-04-16 2012-05-16 花王株式会社 油脂組成物
US8784911B2 (en) * 2009-11-05 2014-07-22 Korea Institute Of Oriental Medicine Compositions for treatment and prevention of diabetic complications using Osteomeles schwerinae
JP6151003B2 (ja) * 2012-10-26 2017-06-21 学校法人近畿大学 カンカニクジュヨウから得られる抗糖尿病剤、ヒト又は動物用医薬および機能性食品
KR101510257B1 (ko) 2013-12-30 2015-04-09 한림대학교 산학협력단 크리신(ｃｈｒｙｓｉｎ)을 유효성분으로 하는 당뇨합병성 신세뇨관 섬유화로 인한 신장섬유증 억제용 조성물
WO2019175587A1 (en) * 2018-03-13 2019-09-19 Nuchido Limited Compositions
CN117298133B (zh) * 2023-11-30 2024-02-23 唐宁医药科技(济南)有限公司 归知糖疽有效成分配方在制备治疗糖尿病足药物中的应用
CN119656183A (zh) * 2024-09-30 2025-03-21 唐宁医药科技(济南)有限公司 一种归知糖疽有效成分配方在治疗糖尿病引起的周围神经病变中的应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4250097A (en) 1978-03-08 1981-02-10 Syntex (U.S.A.) Inc. Compositions for and a method of preventing diabetic complications
FR2543550B1 (fr) * 1983-04-01 1985-08-09 Cortial Nouveaux derives de la tetrahydroxy-3', 4',5,7 flavone, leur methode de preparation et leur emploi therapeutique
US6103709A (en) * 1993-12-23 2000-08-15 The Regents Of The University Of California Therapeutically effective 1α,25-dihydroxyvitamin D3 analogs and methods for treatment of vitamin D diseases
US5948443A (en) * 1996-02-23 1999-09-07 Medical Doctor's Research Institute, Inc. Acetylsalicylic acid and micronutrient supplementation for nutritional losses and coronary heart disease
GB9827391D0 (en) * 1998-12-11 1999-02-03 Fundation O N C F Aldose reductase inhibitors and pharmaceutical compositions
AU780233B2 (en) * 1999-04-05 2005-03-10 Randy H. Ziegler Compositions and methods for treatment of diabetes
US6103756A (en) * 1999-08-11 2000-08-15 Vitacost Inc. Ocular orally ingested composition for prevention and treatment of individuals

Also Published As

Publication number Publication date
IL156549A0 (en) 2004-01-04
AU2002231095B2 (en) 2005-11-24
JP2004516257A (ja) 2004-06-03
WO2002049575A2 (en) 2002-06-27
MXPA03005672A (es) 2004-12-03
EP1351679B1 (en) 2010-02-03
NZ526041A (en) 2005-01-28
CA2431079A1 (en) 2002-06-27
EP1351679A2 (en) 2003-10-15
DE60141253D1 (de) 2010-03-25
ATE456957T1 (de) 2010-02-15
AU3109502A (en) 2002-07-01
WO2002049575A3 (en) 2003-07-24
CA2431079C (en) 2010-02-09
EP1351679A4 (en) 2007-03-21
ES2340363T3 (es) 2010-06-02

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