JP4399012B2 - 医薬品および薬剤の計量およびパッケージングさらには移送 - Google Patents
医薬品および薬剤の計量およびパッケージングさらには移送 Download PDFInfo
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- JP4399012B2 JP4399012B2 JP2008048342A JP2008048342A JP4399012B2 JP 4399012 B2 JP4399012 B2 JP 4399012B2 JP 2008048342 A JP2008048342 A JP 2008048342A JP 2008048342 A JP2008048342 A JP 2008048342A JP 4399012 B2 JP4399012 B2 JP 4399012B2
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- powder
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0085—Inhalators using ultrasonics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0065—Inhalators with dosage or measuring devices
- A61M15/0068—Indicating or counting the number of dispensed doses or of remaining doses
- A61M15/008—Electronic counters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0065—Inhalators with dosage or measuring devices
- A61M15/0068—Indicating or counting the number of dispensed doses or of remaining doses
- A61M15/0083—Timers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/02—Inhalators with activated or ionised fluids, e.g. electrohydrodynamic [EHD] or electrostatic devices; Ozone-inhalators with radioactive tagged particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0065—Inhalators with dosage or measuring devices
- A61M15/0068—Indicating or counting the number of dispensed doses or of remaining doses
- A61M15/0081—Locking means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/0003—Accessories therefor, e.g. sensors, vibrators, negative pressure
- A61M2016/0015—Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors
- A61M2016/0018—Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors electrical
- A61M2016/0021—Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors electrical with a proportional output signal, e.g. from a thermistor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/06—Solids
- A61M2202/064—Powder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/50—General characteristics of the apparatus with microprocessors or computers
Description
−従来技術による吸入器の性能が、使用者によって生成される流速に基づくものであること。流速が小さいと、粒子が全体的に解離されることがなく、そのため、患者に対して搬送される薬剤量が悪影響を受けてしまう。
−解離プロセスの一貫性の欠如のために、投与量と薬剤効能とが一致しなくなってしまうこと。
−電気機械的吸入器の駆動のために大きなエネルギーが必要とされ、このため、デバイスのサイズが大きくなってしまって、携帯用途に適さないものとなってしまうこと。
90A 圧電性バイブレータ(バイブレータ)
90B 圧電性バイブレータ(バイブレータ)
208 マイクロホン、空気流検出デバイス(音響的検出部材)
212 空気流通通路(流体通路)
226 静電プレート
228 高周波バイブレータ
238 吸入容量プロセッサ
324 キャリア表面
325A 静電『イメージ』、帯電『イメージ』
328 搬送ベルト
329 カプセル(個別パッケージ)
388 シート(食用シート)
Claims (2)
- 乾燥粉末吸入デバイスのための圧力センサおよびコントローラであって、
前記乾燥粉末吸入デバイスが、チャンバと、前記デバイス内に形成された空気流通通路と、前記チャンバに対して連結されていて前記空気流通通路内へと前記乾燥粉末を導入し得る高周波バイブレータ(228)と、を具備し、
前記圧力センサおよびコントローラが、音響的コントローラを具備し、
該音響的コントローラは、前記空気流通通路内に配置されていて自身の周囲の流体圧力を検出し得るとともに前記流体圧力の周波数および強度を代理する信号(244)を形成し得る音響的検出部材(208)を備え、
前記信号が、前記空気流通通路内へと乾燥粉末を導入し得るように前記高周波バイブレータ(228)を駆動して乾燥粉末を振動させて解離させることまたは前記空気流通通路内へと乾燥粉末を導入しないように前記高周波バイブレータ(228)の駆動を禁止することを制御するようになっていることを特徴とする圧力センサおよびコントローラ。 - 請求項1記載の圧力センサおよびコントローラにおいて、
(a)前記信号が、静電プレート(226)に向けて前記粒子を引きつけて該粒子の前記空気流内への導入を行うような前記静電プレート(226)の駆動または駆動禁止を制御する信号(236)をも有しているという特徴点、
(b)前記信号(248’)が、前記吸入デバイスの前記構成部材を制御するためのタイマーの駆動または駆動禁止を制御するようになっているという特徴点、
(c)前記音響的検出部材(208)が、マイクロホンであるという特徴点、
(d)前記音響的検出部材(208)が、流体圧力トランスデューサであるという特徴点、
(e)前記吸入デバイスが、吸入時に前記吸入デバイス内への空気流入を可能とするための流体通路(212)と、粉末薬剤を振動させて該粉末薬剤を空気流内に導入させるためのバイブレータ機構(228)を備えた乾燥粉末薬剤放出器と、を具備してなり、前記バイブレータ機構が、前記音響的コントローラによって制御されるようになっており、前記粉末薬剤の粒子を引きつけて前記空気流内に浮遊させるための静電プレート(226)を備え、該静電プレートが、前記音響的コントローラによって制御されるようになっているという特徴点、
(f)前記音響的コントローラが、さらに、前記センサの周辺の流速に関連したデータを得るとともに前記吸入デバイスの前記構成部材をさらに制御するためのこのデータを使用するための吸入容量プロセッサ(238)を備え、前記データが、前記吸入デバイスの使用者の吸気および/または排気を代理する最小流速および最大流速を備えているという特徴点、
(g)前記音響的検出部材(208)が、前記センサの周辺における最適流通を得るために前記吸入デバイス内に配置されているという特徴点、
のうちの1つまたは複数の特徴点を備えていることを特徴とする圧力センサおよびコントローラ。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/097,106 US6152130A (en) | 1998-06-12 | 1998-06-12 | Inhalation device with acoustic control |
US09/097,104 US5960609A (en) | 1998-06-12 | 1998-06-12 | Metering and packaging method and device for pharmaceuticals and drugs |
US09/097,105 US6142146A (en) | 1998-06-12 | 1998-06-12 | Inhalation device |
Related Parent Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2000553162A Division JP2002524107A (ja) | 1998-06-12 | 1999-06-14 | 医薬品および薬剤の計量およびパッケージングさらには移送 |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2008132362A JP2008132362A (ja) | 2008-06-12 |
JP4399012B2 true JP4399012B2 (ja) | 2010-01-13 |
Family
ID=27378303
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2000553162A Pending JP2002524107A (ja) | 1998-06-12 | 1999-06-14 | 医薬品および薬剤の計量およびパッケージングさらには移送 |
JP2008048342A Expired - Lifetime JP4399012B2 (ja) | 1998-06-12 | 2008-02-28 | 医薬品および薬剤の計量およびパッケージングさらには移送 |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2000553162A Pending JP2002524107A (ja) | 1998-06-12 | 1999-06-14 | 医薬品および薬剤の計量およびパッケージングさらには移送 |
Country Status (14)
Country | Link |
---|---|
EP (1) | EP1083952B1 (ja) |
JP (2) | JP2002524107A (ja) |
KR (1) | KR100561223B1 (ja) |
CN (2) | CN1202876C (ja) |
AT (1) | ATE312638T1 (ja) |
AU (1) | AU760126B2 (ja) |
BR (1) | BR9911098A (ja) |
CA (1) | CA2334590C (ja) |
DE (1) | DE69928928T2 (ja) |
DK (1) | DK1083952T3 (ja) |
ES (1) | ES2253898T3 (ja) |
HK (2) | HK1040646A1 (ja) |
NZ (1) | NZ508663A (ja) |
WO (1) | WO1999064095A2 (ja) |
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GB9623634D0 (en) * | 1996-11-13 | 1997-01-08 | Bpsi Holdings Inc | Method and apparatus for the coating of substrates for pharmaceutical use |
-
1999
- 1999-06-14 WO PCT/US1999/013420 patent/WO1999064095A2/en active IP Right Grant
- 1999-06-14 CN CNB998092630A patent/CN1202876C/zh not_active Expired - Lifetime
- 1999-06-14 NZ NZ508663A patent/NZ508663A/xx not_active IP Right Cessation
- 1999-06-14 CA CA002334590A patent/CA2334590C/en not_active Expired - Lifetime
- 1999-06-14 EP EP99930254A patent/EP1083952B1/en not_active Expired - Lifetime
- 1999-06-14 AT AT99930254T patent/ATE312638T1/de active
- 1999-06-14 DK DK99930254T patent/DK1083952T3/da active
- 1999-06-14 JP JP2000553162A patent/JP2002524107A/ja active Pending
- 1999-06-14 DE DE69928928T patent/DE69928928T2/de not_active Expired - Lifetime
- 1999-06-14 CN CN2004100859261A patent/CN1623607B/zh not_active Expired - Lifetime
- 1999-06-14 ES ES99930254T patent/ES2253898T3/es not_active Expired - Lifetime
- 1999-06-14 BR BR9911098-9A patent/BR9911098A/pt not_active IP Right Cessation
- 1999-06-14 KR KR1020007014075A patent/KR100561223B1/ko not_active IP Right Cessation
- 1999-06-14 AU AU46831/99A patent/AU760126B2/en not_active Expired
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2002
- 2002-03-19 HK HK02102086A patent/HK1040646A1/xx not_active IP Right Cessation
-
2005
- 2005-12-07 HK HK05111214.2A patent/HK1077530A1/xx not_active IP Right Cessation
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2008
- 2008-02-28 JP JP2008048342A patent/JP4399012B2/ja not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
HK1077530A1 (en) | 2006-02-17 |
DE69928928T2 (de) | 2006-08-03 |
ES2253898T3 (es) | 2006-06-01 |
CA2334590C (en) | 2009-08-18 |
KR100561223B1 (ko) | 2006-03-15 |
KR20010072605A (ko) | 2001-07-31 |
AU4683199A (en) | 1999-12-30 |
WO1999064095A2 (en) | 1999-12-16 |
AU760126B2 (en) | 2003-05-08 |
CA2334590A1 (en) | 1999-12-16 |
CN1202876C (zh) | 2005-05-25 |
HK1040646A1 (en) | 2002-06-21 |
CN1320054A (zh) | 2001-10-31 |
EP1083952A2 (en) | 2001-03-21 |
CN1623607B (zh) | 2011-03-30 |
DK1083952T3 (da) | 2006-04-24 |
EP1083952B1 (en) | 2005-12-14 |
BR9911098A (pt) | 2002-01-29 |
JP2002524107A (ja) | 2002-08-06 |
DE69928928D1 (de) | 2006-01-19 |
WO1999064095A3 (en) | 2000-03-02 |
JP2008132362A (ja) | 2008-06-12 |
ATE312638T1 (de) | 2005-12-15 |
CN1623607A (zh) | 2005-06-08 |
NZ508663A (en) | 2003-02-28 |
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