JP4394838B2 - 溶液中の高分子の濃縮および／または精製のための装置およびそのような装置の製造方法 - Google Patents

溶液中の高分子の濃縮および／または精製のための装置およびそのような装置の製造方法 Download PDF

Info

Publication number
JP4394838B2
JP4394838B2 JP2000599492A JP2000599492A JP4394838B2 JP 4394838 B2 JP4394838 B2 JP 4394838B2 JP 2000599492 A JP2000599492 A JP 2000599492A JP 2000599492 A JP2000599492 A JP 2000599492A JP 4394838 B2 JP4394838 B2 JP 4394838B2
Authority
JP
Japan
Prior art keywords
membrane
chamber
filtrate
opening
casing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP2000599492A
Other languages
English (en)
Japanese (ja)
Other versions
JP2002537087A5 (https=
JP2002537087A (ja
Inventor
ヴァッサロッティ，ヴィンセンツォ
Original Assignee
ザトーリウス ステディム ビオテーク ゲーエムベーハー
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ザトーリウス ステディム ビオテーク ゲーエムベーハー filed Critical ザトーリウス ステディム ビオテーク ゲーエムベーハー
Publication of JP2002537087A publication Critical patent/JP2002537087A/ja
Publication of JP2002537087A5 publication Critical patent/JP2002537087A5/ja
Application granted granted Critical
Publication of JP4394838B2 publication Critical patent/JP4394838B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Images

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D63/00—Apparatus in general for separation processes using semi-permeable membranes
    • B01D63/08—Flat membrane modules
    • B01D63/087—Single membrane modules
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/14—Ultrafiltration; Microfiltration
    • B01D61/18—Apparatus therefor
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D63/00—Apparatus in general for separation processes using semi-permeable membranes
    • B01D63/08—Flat membrane modules
    • B01D63/081—Manufacturing thereof
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D63/00—Apparatus in general for separation processes using semi-permeable membranes
    • B01D63/16—Rotary, reciprocated or vibrated modules
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5021—Test tubes specially adapted for centrifugation purposes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/34—Purifying; Cleaning
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0681—Filter
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/40—Concentrating samples
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/40—Concentrating samples
    • G01N1/4077—Concentrating samples by other techniques involving separation of suspended solids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/40—Concentrating samples
    • G01N1/4005—Concentrating samples by transferring a selected component through a membrane
    • G01N2001/4016—Concentrating samples by transferring a selected component through a membrane being a selective membrane, e.g. dialysis or osmosis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Water Supply & Treatment (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Pathology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Manufacturing & Machinery (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Clinical Laboratory Science (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Centrifugal Separators (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Sampling And Sample Adjustment (AREA)
  • External Artificial Organs (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
JP2000599492A 1999-02-15 2000-02-08 溶液中の高分子の濃縮および／または精製のための装置およびそのような装置の製造方法 Expired - Lifetime JP4394838B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE9900530-8 1999-02-15
SE9900530A SE9900530D0 (sv) 1999-02-15 1999-02-15 A device for concentrating and/or purifying macromolecules in a solution and a method for manufacturing such a device
PCT/EP2000/000976 WO2000048716A2 (de) 1999-02-15 2000-02-08 Vorrichtung zum konzentrieren und/oder reinigen von makromolekülen in einer lösung und verfahren zum herstellen einer derartigen vorrichtung

Publications (3)

Publication Number Publication Date
JP2002537087A JP2002537087A (ja) 2002-11-05
JP2002537087A5 JP2002537087A5 (https=) 2008-11-20
JP4394838B2 true JP4394838B2 (ja) 2010-01-06

Family

ID=20414497

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2000599492A Expired - Lifetime JP4394838B2 (ja) 1999-02-15 2000-02-08 溶液中の高分子の濃縮および／または精製のための装置およびそのような装置の製造方法

Country Status (7)

Country Link
US (1) US6837995B1 (https=)
EP (1) EP1144095B1 (https=)
JP (1) JP4394838B2 (https=)
AT (1) ATE244053T1 (https=)
DE (3) DE50002721D1 (https=)
SE (1) SE9900530D0 (https=)
WO (1) WO2000048716A2 (https=)

Families Citing this family (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10035750A1 (de) * 2000-07-22 2002-02-07 Forschungszentrum Juelich Gmbh Vorrichtung mit einer Vielzahl von Probenkammern zur Behandlung von Zellen und zur Analyse mittels lichterzeugender Verfahren sowie Filterverbund
DE10114537A1 (de) * 2001-03-21 2002-10-24 Elipsa Gmbh Array von Filtrationsmembranen mit systematisch variierenden Trenneigenschaften, Verfahren zur Herstellung und Verwendung
DE10160429B4 (de) * 2001-12-08 2008-05-08 Sartorius Stedim Biotech Gmbh Filter mit einem elektronischen Speicherelement
DE102005051645B4 (de) * 2005-10-26 2018-10-18 Rapid Sampling Technologies Ag Einrichtung zur Fraktionierung von mit Partikeln beladenen Flüssigkeiten
US8357296B2 (en) 2007-09-24 2013-01-22 Emd Millipore Corporation Centrifugal filter
DE202011002150U1 (de) * 2011-01-31 2011-07-20 Sartorius Stedim Biotech Gmbh Filtrationsbehälter
DE202011002149U1 (de) 2011-01-31 2011-10-26 Sartorius Stedim Biotech Gmbh Filtrationsbehälter
US9304070B2 (en) 2011-07-13 2016-04-05 Emd Millipore Corporation All-in-one sample preparation device and method
EP2727643A1 (en) 2012-10-31 2014-05-07 Takeda GmbH Cross-flow ultrafiltration device and method for concentration of pharmaceutical compositions
US11293021B1 (en) 2016-06-23 2022-04-05 Inscripta, Inc. Automated cell processing methods, modules, instruments, and systems
US10011849B1 (en) 2017-06-23 2018-07-03 Inscripta, Inc. Nucleic acid-guided nucleases
US9982279B1 (en) 2017-06-23 2018-05-29 Inscripta, Inc. Nucleic acid-guided nucleases
MX2019015505A (es) 2017-06-30 2020-07-28 Inscripta Inc Metodos, modulos, instrumentos y sistemas de procesamiento de celulas automatizados.
US10738327B2 (en) 2017-08-28 2020-08-11 Inscripta, Inc. Electroporation cuvettes for automation
EP3687621A4 (en) 2017-09-30 2021-08-11 Inscripta, Inc. Flow through electroporation instrumentation
WO2019190874A1 (en) 2018-03-29 2019-10-03 Inscripta, Inc. Automated control of cell growth rates for induction and transformation
US10376889B1 (en) 2018-04-13 2019-08-13 Inscripta, Inc. Automated cell processing instruments comprising reagent cartridges
US10858761B2 (en) 2018-04-24 2020-12-08 Inscripta, Inc. Nucleic acid-guided editing of exogenous polynucleotides in heterologous cells
US10526598B2 (en) 2018-04-24 2020-01-07 Inscripta, Inc. Methods for identifying T-cell receptor antigens
US10508273B2 (en) 2018-04-24 2019-12-17 Inscripta, Inc. Methods for identifying selective binding pairs
AU2019292919A1 (en) 2018-06-30 2021-03-11 Inscripta, Inc. Instruments, modules, and methods for improved detection of edited sequences in live cells
US10752874B2 (en) 2018-08-14 2020-08-25 Inscripta, Inc. Instruments, modules, and methods for improved detection of edited sequences in live cells
US11142740B2 (en) 2018-08-14 2021-10-12 Inscripta, Inc. Detection of nuclease edited sequences in automated modules and instruments
US10532324B1 (en) 2018-08-14 2020-01-14 Inscripta, Inc. Instruments, modules, and methods for improved detection of edited sequences in live cells
AU2019368215B2 (en) 2018-10-22 2023-05-18 Inscripta, Inc. Engineered enzymes
US11214781B2 (en) 2018-10-22 2022-01-04 Inscripta, Inc. Engineered enzyme
US10864483B2 (en) * 2018-11-16 2020-12-15 Integrated Protein Technologies, Snc. Molecular weight filtration system and apparatus
EP3702017A1 (en) 2019-02-26 2020-09-02 Sartorius Stedim Lab Ltd. Crossflow filter device
CN113631713A (zh) 2019-03-25 2021-11-09 因思科瑞普特公司 酵母中的同时多重基因组编辑
US11001831B2 (en) 2019-03-25 2021-05-11 Inscripta, Inc. Simultaneous multiplex genome editing in yeast
AU2020288623A1 (en) 2019-06-06 2022-01-06 Inscripta, Inc. Curing for recursive nucleic acid-guided cell editing
US10907125B2 (en) 2019-06-20 2021-02-02 Inscripta, Inc. Flow through electroporation modules and instrumentation
US11203762B2 (en) 2019-11-19 2021-12-21 Inscripta, Inc. Methods for increasing observed editing in bacteria
KR102776469B1 (ko) 2019-12-10 2025-03-05 인스크립타 인코포레이티드 신규 mad 뉴클레아제
US10704033B1 (en) 2019-12-13 2020-07-07 Inscripta, Inc. Nucleic acid-guided nucleases
EP4069851A4 (en) 2019-12-18 2023-11-22 Inscripta, Inc. Cascade/dcas3 complementation assays for in vivo detection of nucleic acid-guided nuclease edited cells
AU2021213705A1 (en) 2020-01-27 2022-06-16 Inscripta, Inc. Electroporation modules and instrumentation
US20210332388A1 (en) 2020-04-24 2021-10-28 Inscripta, Inc. Compositions, methods, modules and instruments for automated nucleic acid-guided nuclease editing in mammalian cells
GB2598397B (en) 2020-09-01 2024-08-14 Uni Glory Holdings Ltd A chroma key and presentation system, method, and kit
WO2022060749A1 (en) 2020-09-15 2022-03-24 Inscripta, Inc. Crispr editing to embed nucleic acid landing pads into genomes of live cells
US11512297B2 (en) 2020-11-09 2022-11-29 Inscripta, Inc. Affinity tag for recombination protein recruitment
AU2021415461A1 (en) 2021-01-04 2023-08-17 Inscripta, Inc. Mad nucleases
US20240376451A1 (en) 2021-01-07 2024-11-14 Inscripta, Inc. Mad nucleases
US20240075431A1 (en) 2021-01-22 2024-03-07 Paul Charles Reardon Filter
EP4032603A1 (en) 2021-01-22 2022-07-27 Paul Charles Reardon Filter
US11884924B2 (en) 2021-02-16 2024-01-30 Inscripta, Inc. Dual strand nucleic acid-guided nickase editing

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3583627A (en) * 1969-09-04 1971-06-08 Onslow H Wilson Apparatus for the concentration of macromolecules and subcellular particles from dilute solutions
US4948564A (en) * 1986-10-28 1990-08-14 Costar Corporation Multi-well filter strip and composite assemblies
DE3725445C2 (de) * 1987-07-31 1995-10-05 Kyburz & Nicolaisen Testzelle für Membranverfahren
US4944876A (en) * 1989-10-03 1990-07-31 Telectro-Mek, Inc. Filter capsule with inlet dispersion
SU1738314A1 (ru) * 1990-07-12 1992-06-07 Всесоюзный Научно-Исследовательский Институт Химических Реактивов И Особо Чистых Химических Веществ Мембранный элемент
SE9301759D0 (sv) * 1993-05-21 1993-05-21 Vincenzo Vassarotti Centrifugal method for concentrating macromolecules from a solution and device for carrying out said method

Also Published As

Publication number Publication date
EP1144095A3 (de) 2002-03-06
DE50002721D1 (de) 2003-08-07
WO2000048716A3 (de) 2001-11-01
DE20002188U1 (de) 2000-05-11
DE10005427A1 (de) 2000-08-17
JP2002537087A (ja) 2002-11-05
SE9900530D0 (sv) 1999-02-15
EP1144095B1 (de) 2003-07-02
US6837995B1 (en) 2005-01-04
ATE244053T1 (de) 2003-07-15
WO2000048716A2 (de) 2000-08-24
EP1144095A2 (de) 2001-10-17

Similar Documents

Publication Publication Date Title
JP4394838B2 (ja) 溶液中の高分子の濃縮および／または精製のための装置およびそのような装置の製造方法
US10688416B2 (en) Portable filtration unit
US8057672B2 (en) Disposable multi-layered filtration device for the separation of blood plasma
EP0651675B1 (en) Centrifugal method for concentrating macromolecules from a solution and device for carrying out said method
US5601711A (en) Selective separation filter device
EP0596482B1 (en) Multiwell test apparatus
CN101808708B (zh) 离心过滤器
CN104105539B (zh) 过滤模块和模块化过滤系统
CA2633349A1 (en) Filtration assembly and methods for making and using same
US5674395A (en) Multiple sample separator
US3464562A (en) Dialyzing apparatus and method of making the same
US4231879A (en) Apparatus for selective separation of matter through semi-permeable membranes
US5490927A (en) Filtration apparatus with membrane filter unit
US20040045890A1 (en) Hollow fiber membrane cassette
KR20240024857A (ko) 직교류 필터 장치
EP1359993B1 (en) Hollow fiber membrane cassette
US20050103703A1 (en) Method of assembling a filtration plate
AU2002236864A1 (en) Hollow fiber membrane cassette
JP2004524140A5 (https=)
JPS6323099Y2 (https=)
JP7173004B2 (ja) 流体デバイス及び被分離物質の分離方法
JPH10225625A (ja) 液体分離装置および膜エレメントの接続方法
JPS59160511A (ja) 濾過装置
US7875246B2 (en) Filter column module
CN101199917A (zh) 微射流系统中的微射流部件的实现

Legal Events

Date Code Title Description
A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20070207

A711 Notification of change in applicant

Free format text: JAPANESE INTERMEDIATE CODE: A711

Effective date: 20071130

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20080619

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20080701

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20080922

A524 Written submission of copy of amendment under article 19 pct

Free format text: JAPANESE INTERMEDIATE CODE: A524

Effective date: 20080922

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20090203

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20090501

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20091006

A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20091016

R150 Certificate of patent or registration of utility model

Ref document number: 4394838

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150

Free format text: JAPANESE INTERMEDIATE CODE: R150

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20121023

Year of fee payment: 3

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20131023

Year of fee payment: 4

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

EXPY Cancellation because of completion of term