JP4331476B2 - プリン−２，６−ジアミンのピラゾロ［３，４−ｄ］ピリミジンアナローグを含有する核酸結合性化合物およびそれらの使用 - Google Patents

プリン−２，６−ジアミンのピラゾロ［３，４−ｄ］ピリミジンアナローグを含有する核酸結合性化合物およびそれらの使用 Download PDF

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JP4331476B2
JP4331476B2 JP2002518237A JP2002518237A JP4331476B2 JP 4331476 B2 JP4331476 B2 JP 4331476B2 JP 2002518237 A JP2002518237 A JP 2002518237A JP 2002518237 A JP2002518237 A JP 2002518237A JP 4331476 B2 JP4331476 B2 JP 4331476B2
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alkyl
nucleic acid
acid binding
aryl
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JP2004505988A5 (enExample
JP2004505988A (ja
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セーラ，フランク
ベルグマン，フランク
デル エルツ，ヘルベルト フォン
ハインドル，ディーター
シーデル，クリストフ
ベハー，ゲオルグ
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F Hoffmann La Roche AG
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
    • Y10T436/143333—Saccharide [e.g., DNA, etc.]

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2002518237A 2000-08-03 2001-07-31 プリン−２，６−ジアミンのピラゾロ［３，４−ｄ］ピリミジンアナローグを含有する核酸結合性化合物およびそれらの使用 Expired - Lifetime JP4331476B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP00116816 2000-08-03
EP01109438 2001-04-24
PCT/EP2001/008850 WO2002012263A1 (en) 2000-08-03 2001-07-31 Nucleic acid binding compounds containing pyrazolo[3,4-d]pyrimidine analogues of purin-2,6-diamine and their uses

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JP2004505988A JP2004505988A (ja) 2004-02-26
JP2004505988A5 JP2004505988A5 (enExample) 2005-02-24
JP4331476B2 true JP4331476B2 (ja) 2009-09-16

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US (2) US7238795B2 (enExample)
EP (1) EP1307469B1 (enExample)
JP (1) JP4331476B2 (enExample)
AT (1) ATE384731T1 (enExample)
AU (1) AU2001278517A1 (enExample)
CA (1) CA2416631C (enExample)
DE (1) DE60132596T2 (enExample)
ES (1) ES2300346T3 (enExample)
WO (1) WO2002012263A1 (enExample)

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Publication number Publication date
EP1307469B1 (en) 2008-01-23
EP1307469A1 (en) 2003-05-07
ATE384731T1 (de) 2008-02-15
CA2416631A1 (en) 2002-02-14
DE60132596D1 (de) 2008-03-13
US7238795B2 (en) 2007-07-03
US8057997B2 (en) 2011-11-15
AU2001278517A1 (en) 2002-02-18
US20110021365A1 (en) 2011-01-27
WO2002012263A1 (en) 2002-02-14
CA2416631C (en) 2011-11-22
JP2004505988A (ja) 2004-02-26
ES2300346T3 (es) 2008-06-16
US20030198982A1 (en) 2003-10-23
DE60132596T2 (de) 2009-02-19

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