JP4323743B2 - ポリマ・バルブ - Google Patents

ポリマ・バルブ Download PDF

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Publication number
JP4323743B2
JP4323743B2 JP2001507943A JP2001507943A JP4323743B2 JP 4323743 B2 JP4323743 B2 JP 4323743B2 JP 2001507943 A JP2001507943 A JP 2001507943A JP 2001507943 A JP2001507943 A JP 2001507943A JP 4323743 B2 JP4323743 B2 JP 4323743B2
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JP
Japan
Prior art keywords
polymer
channel
micro
responsive
polymer material
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP2001507943A
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English (en)
Japanese (ja)
Other versions
JP2003503716A (ja
JP2003503716A5 (enExample
Inventor
ヘレネ・デランド
ペール・アンデション
アンデッシュ・ラーション
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gyros Patent AB
Original Assignee
Gyros Patent AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gyros Patent AB filed Critical Gyros Patent AB
Publication of JP2003503716A publication Critical patent/JP2003503716A/ja
Publication of JP2003503716A5 publication Critical patent/JP2003503716A5/ja
Application granted granted Critical
Publication of JP4323743B2 publication Critical patent/JP4323743B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K99/00—Subject matter not provided for in other groups of this subclass
    • F16K99/0001—Microvalves
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0093—Microreactors, e.g. miniaturised or microfabricated reactors
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502738—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by integrated valves
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F15—FLUID-PRESSURE ACTUATORS; HYDRAULICS OR PNEUMATICS IN GENERAL
    • F15C—FLUID-CIRCUIT ELEMENTS PREDOMINANTLY USED FOR COMPUTING OR CONTROL PURPOSES
    • F15C5/00—Manufacture of fluid circuit elements; Manufacture of assemblages of such elements integrated circuits
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K13/00—Other constructional types of cut-off apparatus; Arrangements for cutting-off
    • F16K13/08—Arrangements for cutting-off not used
    • F16K13/10—Arrangements for cutting-off not used by means of liquid or granular medium
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K99/00—Subject matter not provided for in other groups of this subclass
    • F16K99/0001—Microvalves
    • F16K99/0003—Constructional types of microvalves; Details of the cutting-off member
    • F16K99/0019—Valves using a microdroplet or microbubble as the valve member
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K99/00—Subject matter not provided for in other groups of this subclass
    • F16K99/0001—Microvalves
    • F16K99/0034—Operating means specially adapted for microvalves
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K99/00—Subject matter not provided for in other groups of this subclass
    • F16K99/0001—Microvalves
    • F16K99/0034—Operating means specially adapted for microvalves
    • F16K99/0036—Operating means specially adapted for microvalves operated by temperature variations
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781—Aspects relating to microreactors
    • B01J2219/00783—Laminate assemblies, i.e. the reactor comprising a stack of plates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781—Aspects relating to microreactors
    • B01J2219/00891—Feeding or evacuation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/12—Specific details about manufacturing devices
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0803—Disc shape
    • B01L2300/0806—Standardised forms, e.g. compact disc [CD] format
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/18—Means for temperature control
    • B01L2300/1861—Means for temperature control using radiation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/06—Valves, specific forms thereof
    • B01L2400/0633—Valves, specific forms thereof with moving parts
    • B01L2400/0661—Valves, specific forms thereof with moving parts shape memory polymer valves

Landscapes

  • Engineering & Computer Science (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Mechanical Engineering (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Theoretical Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Clinical Laboratory Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Computer Hardware Design (AREA)
  • Hematology (AREA)
  • Physics & Mathematics (AREA)
  • Microelectronics & Electronic Packaging (AREA)
  • Fluid Mechanics (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Micromachines (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Valve-Gear Or Valve Arrangements (AREA)
  • Spinning Methods And Devices For Manufacturing Artificial Fibers (AREA)
JP2001507943A 1999-06-30 2000-06-30 ポリマ・バルブ Expired - Lifetime JP4323743B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE9902474-7 1999-06-30
SE9902474A SE9902474D0 (sv) 1999-06-30 1999-06-30 Polymer valves
PCT/EP2000/006142 WO2001002737A1 (en) 1999-06-30 2000-06-30 Polymer valves

Publications (3)

Publication Number Publication Date
JP2003503716A JP2003503716A (ja) 2003-01-28
JP2003503716A5 JP2003503716A5 (enExample) 2007-04-26
JP4323743B2 true JP4323743B2 (ja) 2009-09-02

Family

ID=20416294

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2001507943A Expired - Lifetime JP4323743B2 (ja) 1999-06-30 2000-06-30 ポリマ・バルブ

Country Status (8)

Country Link
US (1) US7104517B1 (enExample)
EP (1) EP1194696B1 (enExample)
JP (1) JP4323743B2 (enExample)
AT (1) ATE256254T1 (enExample)
AU (1) AU5980800A (enExample)
DE (1) DE60007128T2 (enExample)
SE (1) SE9902474D0 (enExample)
WO (1) WO2001002737A1 (enExample)

Families Citing this family (72)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9808836D0 (en) 1998-04-27 1998-06-24 Amersham Pharm Biotech Uk Ltd Microfabricated apparatus for cell based assays
SE9902474D0 (sv) 1999-06-30 1999-06-30 Amersham Pharm Biotech Ab Polymer valves
WO2001007506A2 (en) * 1999-07-23 2001-02-01 The Board Of Trustees Of The University Of Illinois Microfabricated devices and method of manufacturing the same
SE0001790D0 (sv) * 2000-05-12 2000-05-12 Aamic Ab Hydrophobic barrier
US7087203B2 (en) 2000-11-17 2006-08-08 Nagaoka & Co., Ltd. Methods and apparatus for blood typing with optical bio-disc
US7026131B2 (en) 2000-11-17 2006-04-11 Nagaoka & Co., Ltd. Methods and apparatus for blood typing with optical bio-discs
SE0004296D0 (sv) 2000-11-23 2000-11-23 Gyros Ab Device and method for the controlled heating in micro channel systems
WO2002046721A2 (en) 2000-12-08 2002-06-13 Burstein Technologies, Inc. Optical discs for measuring analytes
US7054258B2 (en) 2000-12-08 2006-05-30 Nagaoka & Co., Ltd. Optical disc assemblies for performing assays
US7091034B2 (en) 2000-12-15 2006-08-15 Burstein Technologies, Inc. Detection system for disk-based laboratory and improved optical bio-disc including same
WO2002075312A1 (en) 2001-03-19 2002-09-26 Gyros Ab Characterization of reaction variables
US7429354B2 (en) 2001-03-19 2008-09-30 Gyros Patent Ab Structural units that define fluidic functions
EP1493014A2 (en) 2001-04-11 2005-01-05 Burstein Technologies, Inc. Multi-parameter assays including analysis discs and methods relating thereto
US6523559B2 (en) * 2001-07-27 2003-02-25 Wisconsin Alumni Research Foundation Self-regulating microfluidic device and method of using the same
US6919058B2 (en) 2001-08-28 2005-07-19 Gyros Ab Retaining microfluidic microcavity and other microfluidic structures
WO2003018198A1 (en) 2001-08-28 2003-03-06 Gyros Ab Retaining microfluidic microcavity and other microfluidic structures
CA2468041A1 (en) 2001-11-20 2003-05-30 Burstein Technologies, Inc. Optical bio-discs and microfluidic devices for analysis of cells
US6532997B1 (en) 2001-12-28 2003-03-18 3M Innovative Properties Company Sample processing device with integral electrophoresis channels
JP4083452B2 (ja) * 2002-03-28 2008-04-30 旭化成株式会社 バルブ機構
WO2003082730A1 (en) * 2002-03-31 2003-10-09 Gyros Ab Efficient mmicrofluidic devices
JP4050971B2 (ja) * 2002-10-08 2008-02-20 株式会社島津製作所 ダイアフラムを用いフィルタ機能を有するバルブ
JPWO2004051229A1 (ja) * 2002-12-02 2006-04-06 日本電気株式会社 液体スイッチおよびそれを用いたマイクロチップ、質量分析システム
EP2096341A1 (en) 2002-12-04 2009-09-02 Spinx, Inc, Devices and methods for programmable microscale manipulation of fluids
WO2004067444A1 (en) 2003-01-30 2004-08-12 Gyros Ab Inner walls of microfluidic devices
SE0300823D0 (sv) 2003-03-23 2003-03-23 Gyros Ab Preloaded Microscale Devices
CN1701229A (zh) * 2003-04-28 2005-11-23 松下电器产业株式会社 过滤器及具有该过滤器的生物传感器
JP2007502428A (ja) 2003-05-23 2007-02-08 ユィロス・パテント・アクチボラグ 非湿潤性表面に基づく流体機能
FR2856046B1 (fr) * 2003-06-16 2005-07-29 Biomerieux Sa Microvanne fluidique a ouverture par commande electrique
US7390464B2 (en) 2003-06-19 2008-06-24 Burstein Technologies, Inc. Fluidic circuits for sample preparation including bio-discs and methods relating thereto
US7238269B2 (en) 2003-07-01 2007-07-03 3M Innovative Properties Company Sample processing device with unvented channel
FR2857427B1 (fr) * 2003-07-10 2005-08-26 Biomerieux Sa Vanne a commande electrique comprenant une membrane microporeuse
JP3798011B2 (ja) * 2003-10-15 2006-07-19 松下電器産業株式会社 キャピラリチップにおける流体の流通方法
US20090010819A1 (en) * 2004-01-17 2009-01-08 Gyros Patent Ab Versatile flow path
SE0400181D0 (sv) 2004-01-29 2004-01-29 Gyros Ab Segmented porous and preloaded microscale devices
US7548092B2 (en) 2004-02-25 2009-06-16 Ternarylogic Llc Implementing logic functions with non-magnitude based physical phenomena
US7696785B2 (en) * 2004-02-25 2010-04-13 Ternarylogic Llc Implementing logic functions with non-magnitude based physical phenomena
JP4516346B2 (ja) * 2004-04-14 2010-08-04 積水化学工業株式会社 マイクロ全分析システム
US7313917B2 (en) * 2004-07-01 2008-01-01 Cornell Research Foundation, Inc. Volume phase transition to induce gel movement
US20100164548A1 (en) * 2004-09-08 2010-07-01 Ternarylogic Llc Implementing Logic Functions With Non-Magnitude Based Physical Phenomena
EP1828746B1 (en) 2004-10-18 2016-12-28 Life Technologies Corporation Fluid processing device including composite material flow modulator
EP1849004A1 (en) * 2005-01-17 2007-10-31 Gyros Patent Ab A versatile flow path
KR100682920B1 (ko) * 2005-01-20 2007-02-15 삼성전자주식회사 다중 바이오어세이용 미세유체 칩 및 그 제조방법
KR100668335B1 (ko) * 2005-04-02 2007-01-12 삼성전자주식회사 자성 왁스 플러그를 구비한 마이크로 밸브 및 자성 왁스를이용한 유동 제어 방법
EP1790861A1 (en) * 2005-11-25 2007-05-30 Bonsens AB Microfluidic system
GB0602743D0 (en) * 2006-02-10 2006-03-22 Inverness Medical Switzerland Microfluidic device
US7998433B2 (en) 2006-04-04 2011-08-16 Samsung Electronics Co., Ltd. Valve unit and apparatus having the same
KR100738113B1 (ko) * 2006-05-10 2007-07-12 삼성전자주식회사 상전이형 밸브 및 그 제작방법
US7897113B2 (en) * 2006-07-17 2011-03-01 Industrial Technology Research Institute Fluidic devices and controlling methods thereof
EP1884284A1 (en) * 2006-08-04 2008-02-06 Samsung Electronics Co., Ltd. Closing valve unit and reaction apparatus having closing valve
US8464760B2 (en) 2006-08-16 2013-06-18 Samsung Electronic Co., Ltd. Valve unit, reaction apparatus with the same, and method of forming valve in channel
KR100818274B1 (ko) 2006-09-05 2008-04-01 삼성전자주식회사 미세유동 시스템 제어장치 및 그 방법, 및 미세유동 시스템
KR100846501B1 (ko) * 2006-11-09 2008-07-17 삼성전자주식회사 밸브 유닛 및 이를 구비한 유체 처리 장치
WO2008139697A1 (ja) * 2007-05-10 2008-11-20 Panasonic Corporation チャンバを有する流路部位を含む基板、およびそれを含む多段送液装置
US20090081768A1 (en) * 2007-09-21 2009-03-26 Applera Corporation Devices and Methods for Thermally Isolating Chambers of an Assay Card
GB2457094A (en) * 2008-02-04 2009-08-05 Univ Dublin City A cuvette assembly for holding milking samples
US20100068235A1 (en) * 2008-09-16 2010-03-18 Searete LLC, a limited liability corporation of Deleware Individualizable dosage form
US20100068153A1 (en) * 2008-09-16 2010-03-18 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Ex vivo activatable final dosage form
US20100069821A1 (en) * 2008-09-16 2010-03-18 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Ex vivo modifiable medicament release-sites final dosage form
US20100068254A1 (en) * 2008-09-16 2010-03-18 Mahalaxmi Gita Bangera Modifying a medicament availability state of a final dosage form
US20100068275A1 (en) * 2008-09-16 2010-03-18 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Personalizable dosage form
US20100069887A1 (en) * 2008-09-16 2010-03-18 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Multiple chamber ex vivo adjustable-release final dosage form
US20100068278A1 (en) * 2008-09-16 2010-03-18 Searete Llc, A Limited Liablity Corporation Of The State Of Delaware Ex vivo modifiable medicament release-associations
DE102009023429B4 (de) 2009-05-29 2013-08-14 Siemens Aktiengesellschaft Ventil für Lab-on-a-Chip-Systeme, Verfahren zum Betätigen und zur Herstellung des Ventils
KR101130698B1 (ko) * 2009-11-03 2012-04-02 삼성전자주식회사 밸브 유닛과 이를 구비한 미세유동장치 및 밸브 유닛의 구동방법
JP5765729B2 (ja) * 2011-01-11 2015-08-19 学校法人 関西大学 光応答性高分子が形成されてなる成形物およびその利用
US9470327B2 (en) 2013-02-20 2016-10-18 Thomas R. Crane Self-obstructing flammable fluid carrying conduit
WO2015173543A1 (en) * 2014-05-12 2015-11-19 University Of Southampton Fluid flow device with flow control and method for making the same
US9993819B2 (en) 2014-12-30 2018-06-12 Stmicroelectronics S.R.L. Apparatus for actuating and reading a centrifugal microfluidic disk for biological and biochemical analyses, and use of the apparatus
DE102015204235B4 (de) * 2015-03-10 2016-12-15 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Fluidikstruktur mit Halteabschnitt und Verfahren zum Vereinigen zweier Flüssigkeitsvolumina
US20190277420A1 (en) * 2016-05-18 2019-09-12 Thomas R. Crane Thermally activated flow stop valve
JP2021132569A (ja) * 2020-02-26 2021-09-13 横河電機株式会社 拡散制御機構及びその製造方法
ES2887874B2 (es) * 2020-06-23 2022-11-18 Consejo Superior Investigacion Valvula microfluidica, procedimiento de fabricacion y usos de la misma

Family Cites Families (57)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4585652A (en) * 1984-11-19 1986-04-29 Regents Of The University Of Minnesota Electrochemical controlled release drug delivery system
US4874500A (en) * 1987-07-15 1989-10-17 Sri International Microelectrochemical sensor and sensor array
US5062841A (en) * 1988-08-12 1991-11-05 The Regents Of The University Of California Implantable, self-regulating mechanochemical insulin pump
JPH05205984A (ja) * 1992-01-27 1993-08-13 Nec Corp 積層型固体電解コンデンサ
DE69411709D1 (de) * 1993-01-21 1998-08-20 Mayo Foundation Mikropartikelschaltvorrichtung
US5290240A (en) * 1993-02-03 1994-03-01 Pharmetrix Corporation Electrochemical controlled dispensing assembly and method for selective and controlled delivery of a dispensing fluid
US5417235A (en) * 1993-07-28 1995-05-23 Regents Of The University Of Michigan Integrated microvalve structures with monolithic microflow controller
US5368704A (en) * 1993-08-06 1994-11-29 Teknekron Corporation Micro-electrochemical valves and method
JP3403233B2 (ja) 1994-01-20 2003-05-06 テルモ株式会社 バルーンカテーテル
JP2682478B2 (ja) * 1994-12-12 1997-11-26 日本電気株式会社 チップ状固体電解コンデンサ及びその製造方法
US5797898A (en) * 1996-07-02 1998-08-25 Massachusetts Institute Of Technology Microchip drug delivery devices
SE9602638D0 (sv) 1996-07-03 1996-07-03 Pharmacia Biotech Ab An improved method for the capillary electrophoresis of nucleic acids, proteins and low molecular charged compounds
DE19749011A1 (de) * 1996-11-19 1998-05-20 Lang Volker Mikroventil
US5932799A (en) * 1997-07-21 1999-08-03 Ysi Incorporated Microfluidic analyzer module
US6015266A (en) * 1997-08-27 2000-01-18 Baker Hughes Incorporated Reactive material reciprocating submersible pump
US5984197A (en) * 1998-02-12 1999-11-16 C. Alan Sugarek Thermostat
GB9808836D0 (en) 1998-04-27 1998-06-24 Amersham Pharm Biotech Uk Ltd Microfabricated apparatus for cell based assays
US20040202579A1 (en) 1998-05-08 2004-10-14 Anders Larsson Microfluidic device
GB9809943D0 (en) 1998-05-08 1998-07-08 Amersham Pharm Biotech Ab Microfluidic device
SE9803734D0 (sv) 1998-10-30 1998-10-30 Amersham Pharm Biotech Ab Liquid handling system
GB9828785D0 (en) 1998-12-30 1999-02-17 Amersham Pharm Biotech Ab Sequencing systems
US7261859B2 (en) 1998-12-30 2007-08-28 Gyros Ab Microanalysis device
SE9901100D0 (sv) 1999-03-24 1999-03-24 Amersham Pharm Biotech Ab Surface and tis manufacture and uses
SE9901306D0 (sv) 1999-04-09 1999-04-09 Amersham Pharm Biotech Ab Improved TIRF chamber
US6406605B1 (en) * 1999-06-01 2002-06-18 Ysi Incorporated Electroosmotic flow controlled microfluidic devices
SE9902474D0 (sv) 1999-06-30 1999-06-30 Amersham Pharm Biotech Ab Polymer valves
GB2355717A (en) 1999-10-28 2001-05-02 Amersham Pharm Biotech Uk Ltd DNA isolation method
SE9903919D0 (sv) 1999-10-29 1999-10-29 Amersham Pharm Biotech Ab Device for dispensing droplets
SE9904802D0 (sv) 1999-12-23 1999-12-23 Amersham Pharm Biotech Ab Microfluidic surfaces
US6884395B2 (en) 2000-05-12 2005-04-26 Gyros Ab Integrated microfluidic disc
SE0000300D0 (sv) 2000-01-30 2000-01-30 Amersham Pharm Biotech Ab Microfluidic assembly, covering method for the manufacture of the assembly and the use of the assembly
SE0001790D0 (sv) 2000-05-12 2000-05-12 Aamic Ab Hydrophobic barrier
US6431212B1 (en) * 2000-05-24 2002-08-13 Jon W. Hayenga Valve for use in microfluidic structures
SE0004297D0 (sv) 2000-11-23 2000-11-23 Gyros Ab Device for thermal cycling
SE0004296D0 (sv) 2000-11-23 2000-11-23 Gyros Ab Device and method for the controlled heating in micro channel systems
US20040099310A1 (en) 2001-01-05 2004-05-27 Per Andersson Microfluidic device
US6653625B2 (en) 2001-03-19 2003-11-25 Gyros Ab Microfluidic system (MS)
US7429354B2 (en) 2001-03-19 2008-09-30 Gyros Patent Ab Structural units that define fluidic functions
WO2002075312A1 (en) 2001-03-19 2002-09-26 Gyros Ab Characterization of reaction variables
US6717136B2 (en) 2001-03-19 2004-04-06 Gyros Ab Microfludic system (EDI)
CA2442342A1 (en) 2001-03-19 2002-09-26 Gyros Ab A microfluidic system (edi)
US6919058B2 (en) 2001-08-28 2005-07-19 Gyros Ab Retaining microfluidic microcavity and other microfluidic structures
US20030054563A1 (en) 2001-09-17 2003-03-20 Gyros Ab Detector arrangement for microfluidic devices
US7189368B2 (en) 2001-09-17 2007-03-13 Gyros Patent Ab Functional unit enabling controlled flow in a microfluidic device
US20050214442A1 (en) 2001-11-27 2005-09-29 Anders Larsson Surface and its manufacture and uses
US7221783B2 (en) 2001-12-31 2007-05-22 Gyros Patent Ab Method and arrangement for reducing noise
US7238255B2 (en) 2001-12-31 2007-07-03 Gyros Patent Ab Microfluidic device and its manufacture
WO2003082730A1 (en) 2002-03-31 2003-10-09 Gyros Ab Efficient mmicrofluidic devices
US6955738B2 (en) 2002-04-09 2005-10-18 Gyros Ab Microfluidic devices with new inner surfaces
US20050277195A1 (en) 2002-04-30 2005-12-15 Gyros Ab Integrated microfluidic device (ea)
JP4423189B2 (ja) 2002-05-31 2010-03-03 ユィロス・パテント・アクチボラグ 表面プラズモン共鳴に基づく検出装置
SE0300822D0 (sv) 2003-03-23 2003-03-23 Gyros Ab A collection of Micro Scale Devices
JP5171034B2 (ja) 2003-03-23 2013-03-27 ユィロス・パテント・アクチボラグ 充填済みのマイクロスケール装置
US20050042770A1 (en) 2003-05-23 2005-02-24 Gyros Ab Fluidic functions based on non-wettable surfaces
JP2007502428A (ja) 2003-05-23 2007-02-08 ユィロス・パテント・アクチボラグ 非湿潤性表面に基づく流体機能
US7776272B2 (en) 2003-10-03 2010-08-17 Gyros Patent Ab Liquid router
US8592219B2 (en) 2005-01-17 2013-11-26 Gyros Patent Ab Protecting agent

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WO2001002737A1 (en) 2001-01-11
DE60007128D1 (de) 2004-01-22
US7104517B1 (en) 2006-09-12
SE9902474D0 (sv) 1999-06-30
ATE256254T1 (de) 2003-12-15
DE60007128T2 (de) 2004-09-02
AU5980800A (en) 2001-01-22
EP1194696B1 (en) 2003-12-10
EP1194696A1 (en) 2002-04-10

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