JP4318921B2 - 移植片の機能発現遅延の処置のための医薬の製造のためのリンパ球ホーミング促進剤の使用 - Google Patents

移植片の機能発現遅延の処置のための医薬の製造のためのリンパ球ホーミング促進剤の使用 Download PDF

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Publication number
JP4318921B2
JP4318921B2 JP2002567283A JP2002567283A JP4318921B2 JP 4318921 B2 JP4318921 B2 JP 4318921B2 JP 2002567283 A JP2002567283 A JP 2002567283A JP 2002567283 A JP2002567283 A JP 2002567283A JP 4318921 B2 JP4318921 B2 JP 4318921B2
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Japan
Prior art keywords
compound
pharmaceutically acceptable
amino
rapamycin
agent
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Expired - Fee Related
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JP2002567283A
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English (en)
Japanese (ja)
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JP2004527490A (ja
JP2004527490A5 (enExample
Inventor
マルク・ビゴー
フォルカー・ブリンクマン
トーマス・サブリンスキー
Original Assignee
ノバルティス アクチエンゲゼルシャフト
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Priority claimed from GB0104438A external-priority patent/GB0104438D0/en
Priority claimed from GB0105000A external-priority patent/GB0105000D0/en
Application filed by ノバルティス アクチエンゲゼルシャフト filed Critical ノバルティス アクチエンゲゼルシャフト
Publication of JP2004527490A publication Critical patent/JP2004527490A/ja
Publication of JP2004527490A5 publication Critical patent/JP2004527490A5/ja
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/133Amines having hydroxy groups, e.g. sphingosine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/131Amines acyclic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/20Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/201Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having one or two double bonds, e.g. oleic, linoleic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Emergency Medicine (AREA)
  • Transplantation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
JP2002567283A 2001-02-22 2002-02-21 移植片の機能発現遅延の処置のための医薬の製造のためのリンパ球ホーミング促進剤の使用 Expired - Fee Related JP4318921B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0104438A GB0104438D0 (en) 2001-02-22 2001-02-22 Organic compounds
GB0105000A GB0105000D0 (en) 2001-02-28 2001-02-28 Organic compounds
PCT/EP2002/001860 WO2002067915A1 (en) 2001-02-22 2002-02-21 Use of accelerated lymphocyte homing agents for the manufacture of a medicament for the treatment of delayed graft function

Publications (3)

Publication Number Publication Date
JP2004527490A JP2004527490A (ja) 2004-09-09
JP2004527490A5 JP2004527490A5 (enExample) 2005-05-26
JP4318921B2 true JP4318921B2 (ja) 2009-08-26

Family

ID=26245749

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2002567283A Expired - Fee Related JP4318921B2 (ja) 2001-02-22 2002-02-21 移植片の機能発現遅延の処置のための医薬の製造のためのリンパ球ホーミング促進剤の使用

Country Status (11)

Country Link
US (2) US20040087662A1 (enExample)
EP (1) EP1368015B1 (enExample)
JP (1) JP4318921B2 (enExample)
CN (1) CN100479814C (enExample)
AT (1) ATE335475T1 (enExample)
BR (1) BR0207434A (enExample)
CA (1) CA2435739A1 (enExample)
DE (1) DE60213766T2 (enExample)
ES (1) ES2267993T3 (enExample)
PT (1) PT1368015E (enExample)
WO (1) WO2002067915A1 (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL364359A1 (en) * 2001-06-08 2004-12-13 Novartis Ag Treatment or prophylaxis of insulin-producing cell graft rejection
ATE435202T1 (de) 2002-01-11 2009-07-15 Daiichi Sankyo Co Ltd Aminoalkoholderivat oder phosphonsäurederivat und diese enthaltende medizinische zusammensetzung
CN1921847B (zh) 2004-02-24 2010-06-16 三共株式会社 氨基醇化合物
SI1772145T1 (sl) * 2004-07-16 2011-06-30 Kyorin Seiyaku Kk Postopek za učinkovito uporabo zdravila in postopek za preprečevanje stranskih učinkov
PT2511262T (pt) * 2004-10-12 2017-03-30 Kyorin Seiyaku Kk Processo para a produção de cloridrato de 2-amino-2-[2-[4-(3- benziloxi-feniltio)-2-clorofenil[etil]-1,3-propanodiol
WO2007043433A1 (ja) * 2005-10-07 2007-04-19 Kyorin Pharmaceutical Co., Ltd. 2-アミノ-1,3-プロパンジオール誘導体を有効成分とする肝臓疾患治療剤および肝臓疾患治療方法
TWI389683B (zh) * 2006-02-06 2013-03-21 Kyorin Seiyaku Kk A therapeutic agent for an inflammatory bowel disease or an inflammatory bowel disease treatment using a 2-amino-1,3-propanediol derivative as an active ingredient
SG174028A1 (en) * 2006-08-08 2011-09-29 Kyorin Seiyaku Kk Aminophosphoric acid ester derivative and s1p receptor modulator containing the same as active ingredient
SG174029A1 (en) * 2006-08-08 2011-09-29 Kyorin Seiyaku Kk Aminoalcohol derivative and immunosuppressant containing the same as active ingredient
JP5452237B2 (ja) 2008-02-07 2014-03-26 杏林製薬株式会社 アミノアルコール誘導体を有効成分とする炎症性腸疾患の治療剤又は予防剤

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3928572A (en) * 1971-02-11 1975-12-23 Ayerst Mckenna & Harrison Myriocin and process of preparation
DK0627406T3 (da) * 1992-10-21 1999-07-12 Taito Co 2-Amino-1,3-propandiolforbindelser og immunundertrykkende midler
RU2156127C2 (ru) * 1995-12-28 2000-09-20 Еситоми Фармасьютикал Индустриз, Лтд. Препарат местного применения для иммуносупрессии и лечения аутоиммунных или аллергических заболеваний
GB9624038D0 (en) * 1996-11-19 1997-01-08 Sandoz Ltd Organic compounds
DK1319651T3 (da) * 1997-04-04 2005-08-01 Mitsubishi Pharma Corp 2-aminopropan-1,3-diolforbindelser, medicinsk anvendelse deraf og mellemprodukter til syntese af disse
JPH1180026A (ja) * 1997-09-02 1999-03-23 Yoshitomi Pharmaceut Ind Ltd 新規免疫抑制剤、その使用方法およびその同定方法
PL364359A1 (en) * 2001-06-08 2004-12-13 Novartis Ag Treatment or prophylaxis of insulin-producing cell graft rejection

Also Published As

Publication number Publication date
CN100479814C (zh) 2009-04-22
HK1060855A1 (en) 2004-08-27
CA2435739A1 (en) 2002-09-06
DE60213766D1 (de) 2006-09-21
DE60213766T2 (de) 2007-08-02
BR0207434A (pt) 2004-07-06
CN1492757A (zh) 2004-04-28
ES2267993T3 (es) 2007-03-16
EP1368015B1 (en) 2006-08-09
JP2004527490A (ja) 2004-09-09
US20080015261A1 (en) 2008-01-17
US20040087662A1 (en) 2004-05-06
WO2002067915A1 (en) 2002-09-06
PT1368015E (pt) 2006-12-29
EP1368015A1 (en) 2003-12-10
ATE335475T1 (de) 2006-09-15

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