JP4236131B2

JP4236131B2 - Medical container

Info

Publication number: JP4236131B2
Application number: JP15143896A
Authority: JP
Inventors: 英二川本
Original assignee: TRUMO KABUSHIKI KAISHA
Current assignee: TRUMO KABUSHIKI KAISHA
Priority date: 1996-06-13
Filing date: 1996-06-13
Publication date: 2009-03-11
Anticipated expiration: 2016-06-13
Also published as: JPH09327498A

Description

【０００１】
【発明の属する技術分野】
本発明は、２つ以上の成分を混合して患者に投与するための医療用容器に関する。特に、腹膜透析液、静注用輸液剤、液状栄養剤などのように２つ以上の液剤を用事混合して患者に投与するための医療用容器に関する。
【０００２】
【従来の技術】
従来より使用されている腹膜透析液は、ブドウ糖の分解・着色を防ぐために薬液のｐＨが５.０〜６.０の範囲になるように処方されているが、この生理的に逸脱したｐＨが腹膜の機能低下に関係していることが知られて以来、生体適合性の高い腹膜透析液として重炭酸を配合してｐＨを中性にする腹膜透析液の開発が行われている。腹膜透析液のｐＨは配合されているブドウ糖の安定性に大きな影響を与えており、現在の市販されている製品のｐＨをそのまま中性にすると製造時（高圧蒸気滅菌などの熱滅菌時）あるいは保管時にブドウ糖が分解して薬液の着色がみられ、製品価値が著しく低下してしまうことになる。
【０００３】
そこで、ブドウ糖の分解・着色を抑制したままｐＨを高くする方法として、ブドウ糖を含む成分と、ｐＨの高い重炭酸を含む成分を使用時まで別々に収容し、使用直前に無菌的に混合する用事混合タイプの腹膜透析液の開発が行われている。また、輸液剤や液状栄養剤などで、還元糖やアミノ酸のように反応しやすい成分や、ビタミン等の薬液のｐＨに大きく影響を受ける成分が配合されている場合にも、複数の液を使用直前に混合して投与するタイプの薬剤が多数開発されている。
【０００４】
また、腹膜透析液に限らず、静注用輸液剤や経腸栄養剤などにおいても、同様に製造時（高圧蒸気滅菌などの熱滅菌時）あるいは保管時の成分の安定性等の問題から２種類以上の液剤を用事混合する薬剤が幾つか開発されている。
【０００５】
これらの薬剤は、混合操作を含めて投与されるまで無菌的に取り扱われることが必要であることから、その容器には別々に収容されている各成分が無菌的に混合できるような工夫がなされており、例えば、特開平６−１０５９０５号のような剥離可能な隔壁を有する容器や、特公平７−４１０７１号のように連通部材を有する容器が提案されている。
【０００６】
【発明が解決しようとする課題】
しかしながら、このように２つ以上の液剤を混合して患者に投与する場合、各成分を収容している容器の形態によっては、誤った操作により混合する前の一成分のみを投与してしまう可能性がある。詳細に述べると、これらの容器は閉鎖系にすることにより無菌性を保証し、簡容な操作で各成分間を連通させることを特徴としているため、混合する前の状態においても一方の内容物の取り出しが容易であり、誤投与の防止については全く配慮されていないものである。
そこで本発明の課題は、２つ以上の液剤を混合して使用するような薬剤、例えば腹膜透析液、静注用輸液剤、経腸栄養剤について、混合前の成分がそのまま投与されてしまうことがない医療用器具を提供することにある。
【０００７】
【課題を解決するための手段】
上記課題は以下の本発明により解決される。
（１）熱可塑性樹脂製フィルムからなる袋体に、異なる成分の液剤が収容されている複数の分室と、前記複数の分室の一つに連通して前記異なる成分の液剤の混合液剤を排出する排出口が形成された医療用容器において、前記複数の分室は仕切り手段により液密に仕切られ、かつ前記排出口と前記排出口に連通する分室の間は閉鎖手段により液密に閉鎖されており、これらの仕切り手段および閉鎖手段は前記袋体の外面の少なくとも一部を押圧して生じる内圧によって解除され、かつ、前記閉鎖手段は、前記仕切り手段を解除させる内圧より高い内圧で解除されることを特徴とする医療用容器である。
【０００８】
この時、仕切り手段および閉鎖手段は特に限定する必要はなく、熱可塑性樹脂製フィルムからなる袋体の内面同志を加熱、押圧して形成された熱シールや、袋体の外面から挟むクリップなどが挙げられる。また、閉鎖手段に関しては排出口（管）を薄膜で覆うなどの手段も挙げられる。
【０００９】
また、分室の数は特に限定されず、２室もしくはそれ以上であってもよい。分室が３室以上ある場合、その分室数より１つ少ない数の仕切り手段を設ける。そして、分室のいずれか１つ、好ましくは排出口から遠い分室を押圧することにより仕切り手段を同時もしくは連鎖的に解除させ、最後に更に押圧することにより閉鎖手段を解除させる。
【００１０】
（２）仕切り手段および閉鎖手段が、熱可塑性樹脂製フィルムからなる袋体の内面同士を加熱、押圧して形成された熱シールであることを特徴とする上記（１）に記載の医療用容器である。
【００１１】
（３）熱可塑性樹脂製フィルムからなる袋体に、異なる成分の液剤が別々に収容されている２つの分室と、前記２つの分室の一方に連通して前記異なる成分の液剤の混合液剤を排出する排出口が形成された医療用容器において、前記２つの分室は仕切り手段により液密に仕切られ、かつ前記排出口と前記排出口に連通する分室の間は閉鎖手段により液密に閉鎖されており、前記仕切り手段および前記閉鎖手段は、前記熱可塑性樹脂製フィルムからなる袋体の内面同士を加熱、押圧して形成された熱シールであり、かつ、前記閉鎖手段の熱シールは、前記仕切り手段の熱シールより高い強度で接着されており、前記２つの分室のいずれか一方を外面より押圧して前記仕切り手段に内圧Ａを加えることにより仕切り手段の熱シールが剥離され、さらに前記袋体を外面より押圧して前記閉鎖手段に前記内圧Ａより高い圧力の内圧Ｂをかけることにより閉鎖手段の熱シールが剥離されることを特徴とする医療用容器である。
つまり、閉鎖手段の熱シール強度を仕切り手段の熱シール強度より高いものとすることを特徴とする。
【００１２】
本発明において熱可塑性樹脂としては、特に限定する必要はなく、ポリエチレン、ポリプロピレン、ポリ塩化ビニル、エチレン−酢酸ビニル共重合体、ポリアミド、ポリビニリデンクロライド、ポリビニルフルオライド、ポリトリフルオルクロルエチレン、ポリエチレンテレフタレート、ポリエステル、ポリオレフィン系樹脂およびこれらの混合物や積層体が挙げられる。本発明の医療用容器は衛生面、安全面を考慮して製造後、高圧蒸気滅菌等の熱滅菌や、高周波滅菌などの滅菌処理をすることが好ましいため、それらに耐えられる材質が良い。
【００１３】
本発明において仕切り手段および閉鎖手段の強度の実測値は、通常の人が平面上にのせて上から手の平で押圧して解除できる範囲であれば特に限定されない。例を挙げると、仕切り手段を１０〜１００ｇ/cm²、好ましくは２０〜６０ｇ/cm²の内圧を加えることにより解除されるよう設定し、閉鎖手段は設定した仕切り手段の強度より１０〜７０ｇ/cm²、好ましくは２０〜６０ｇ/cm²高い内圧を加えることにより解除されるよう設定する。
【００１４】
本発明により、腹膜透析液、静注用輸液剤や液状栄養剤（経口・経腸栄養剤）などで複数の液剤を用事混合する場合、混合された液のみを確実に排出することができる。
【００１５】
【発明の実施の形態】
本発明の医療用器具について、以下２つの例を示し説明するが、何らこれらに限定されるものではない。
本発明の医療用容器の一例を図１及び図２を参照しながら説明する。
図１は本発明の医療用容器１の正面図であり、図２は、図１のI−I′線矢視断面図である。
医療用容器１は、一端を熱シール部９、他端を熱シール部１０により内部を無菌状態で密封した袋体２から構成されている。さらに熱シールにより形成された仕切り手段４により、分室１１、分室１２が構成され、分室１１の熱シール部９の近くに熱シールにより形成された閉鎖手段３が設けられている。この際、閉鎖手段３と熱シール部９との間１４は無菌状態であり、また分室１１の容量のロスを避けるため狭い程良い。場合によっては閉鎖手段３と熱シール部９との間１４には、混合液剤が通る回路をプライミングするために生理食塩水などの薬理的に不活性な液体を入れておいても良い。分室１１には液剤１５、分室１２には液剤１６が無菌状態で封入されている。
【００１６】
この時、閉鎖手段３は仕切り手段４以上の強度の熱シールが施されている。具体的には、閉鎖手段は仕切り手段にかかる圧力（内圧Ａ）以上の圧力（内圧Ｂ）をかけて解除される。つまり、閉鎖手段の熱シール強度を仕切り手段の熱シール強度以上とする。熱シール強度の調整は、特に限定しないが熱シール部分の幅や深さなどにより調整することができる。
本発明において、内圧は閉鎖手段もしくは仕切り手段にかかる圧力であるので、袋体または分室の外面を押圧する圧力と一致するとは限らない。
【００１７】
また、一端には熱シール部９に挟まれるようにして排出管５が設けられ、他端には熱シール部１０に挟まれるようにして排出管５より細径の注入管７が設けられ、各々栓体６、栓体８によって封止されている。場合によっては注入管７は設けなくても良い。また、必要により吊り下げるための穴１３が設けられる。
【００１８】
次に、医療用容器１の使用方法について説明する。使用方法として閉鎖手段３が仕切り手段４以上の強度の熱シールを施されている場合、まず、分室１２の外面を手で押圧することにより、それにより生じる分室１２内の内圧によって仕切り手段４の熱シールを剥離させ、液剤１５と液剤１６を混ぜ合わせる。更に強い力で押圧し、閉鎖手段３に仕切り手段４より強い内圧をかけて閉鎖手段３の熱シールを剥離させる。その後、栓体６より瓶針等（図示しない）を差し込み混合液を排出させる。
【００２０】
なお、特に上述した使用方法に限定されず、瓶針等は閉鎖手段および仕切り手段を解除する前に、予め栓体６に刺し込んでおいても良い。また、吊り下げるための穴１３を介して吊り下げることにより効率よく排出作業が可能となる。
【００２１】
液剤１５、液剤１６およびこれらの混合液としては、特に限定しないが、一方の液を重炭酸イオン等を配合した塩基性溶液、他方の液をグルコース、アミノ酸、ペプチド、有機酸等を配合した酸性溶液とし、混合して重炭酸入り中性腹膜透析液や、一方の液をグルコース等の糖類を配合した溶液、他方の液をアミノ酸等の窒素源を配合した溶液とし、または一方の液を水溶性ビタミン類を配合した溶液、薬液Ｂが油溶性ビタミン類を配合した溶液とし、混合して静注用輸液剤や液状栄養剤等が挙げられる。
【００２２】
医療用容器１は、以下の方法により作製される。液剤１５と液剤１６が充填されておらず、閉鎖手段３が形成されていない以外は医療用容器１と同一の構造の容器の排出管５および注入管７から各々液剤１５と液剤１６を無菌的に充填してから、排出管５が上方になるように容器を立てて固定し、閉鎖手段３を形成させる。また、注入管７を設けずに、排出管５が上方になるように容器を立てて固定し、排出管５より液剤１６を無菌的に充填して仕切り手段４を形成させ、次に排出管５より液剤１５を無菌的に充填して閉鎖手段３を形成させる。なお、これらの方法に限定する必要はない。
【００２３】
医療用容器１における閉鎖手段３と仕切り手段４の熱シールの形成方法としては、特に限定されず、通常使用されている熱シールバー等を用いて行うことができる。また、高圧蒸気滅菌等の熱滅菌時に閉鎖手段３と仕切り手段４の部位にブロッキングを生じさせる方法を用いても良い。
【００２４】
【発明の効果】
本発明の医療用器具は、２つ以上の液剤を混合して使用するような薬剤、例えば腹膜透析液、静注用輸液剤、液状栄養剤について、１つの液剤のみを排出することなく、また容易な操作で無菌的にそれぞれの成分を混合して排出することができる。
【図面の簡単な説明】
【図１】本発明の医療用容器の一例の正面図である。
【図２】図１のI−I′線矢視断面図である。
【符号の説明】
１・・・医療用容器
２・・・袋体
３・・・閉鎖手段
４・・・仕切り手段
５・・・排出管
６・・・栓体
７・・・注入管
８・・・栓体
９、１０・・・熱シール部
１１、１２・・・分室
１３・・・吊り下げるための穴
１４・・・閉鎖手段３と熱シール部９との間
１５、１６・・・液剤[0001]
BACKGROUND OF THE INVENTION
The present invention relates to a medical container for mixing and administering two or more components to a patient. In particular, the present invention relates to a medical container for mixing two or more liquid preparations such as peritoneal dialysis solution, intravenous infusion, liquid nutrient, etc., and administering it to a patient.
[0002]
[Prior art]
Conventionally used peritoneal dialysis fluid is formulated so that the pH of the drug solution is in the range of 5.0 to 6.0 in order to prevent the degradation and coloring of glucose. Since it has been known that it is related to a decrease in peritoneal function, peritoneal dialysis fluid has been developed to neutralize pH by adding bicarbonate as a highly biocompatible peritoneal dialysis fluid. The pH of the peritoneal dialysis solution has a great influence on the stability of the glucose blended in. If the pH of the currently marketed product is neutral as it is at the time of production (at the time of heat sterilization such as high-pressure steam sterilization) or Glucose decomposes during storage and the chemical solution is colored, resulting in a significant reduction in product value.
[0003]
Therefore, as a method of increasing the pH while suppressing decomposition and coloring of glucose, a component containing glucose and a component containing bicarbonate having a high pH are separately accommodated until use and mixed aseptically immediately before use. A mixed type peritoneal dialysis solution has been developed. Also, multiple liquids are used when infusions or liquid nutrients contain ingredients that react easily, such as reducing sugars or amino acids, or ingredients that are greatly affected by the pH of chemicals such as vitamins. Many types of drugs that are mixed and administered immediately before have been developed.
[0004]
In addition, not only peritoneal dialysate but also intravenous fluids and enteral nutrients, etc., due to problems such as stability of components during production (heat sterilization such as high-pressure steam sterilization) or storage Several drugs that mix more than one type of liquid preparation have been developed.
[0005]
Since these drugs need to be handled aseptically until they are administered, including mixing operations, the container is devised so that each component contained separately can be mixed aseptically. For example, a container having a detachable partition wall as disclosed in JP-A-6-105905 and a container having a communication member as in JP-B-7-41071 have been proposed.
[0006]
[Problems to be solved by the invention]
However, when two or more liquid preparations are mixed and administered to a patient in this way, depending on the form of the container containing each component, it is possible to administer only one component before mixing due to an incorrect operation. There is sex. In detail, these containers have a closed system to guarantee sterility and to allow easy communication between the components, so that one of the contents can be used even before mixing. Is easy to take out, and no consideration is given to prevention of misadministration.
Therefore, an object of the present invention is that components before mixing are administered as they are for drugs such as peritoneal dialysis solution, intravenous infusion solution, enteral nutrient, etc., which are used by mixing two or more solutions. It is to provide a medical device that does not have any.
[0007]
[Means for Solving the Problems]
The above problems are solved by the present invention described below.
(1) A plurality of compartments in which liquid agents of different components are stored in a bag made of a thermoplastic resin film, and a mixed liquid agent of the liquid agents of different components communicated with one of the plurality of compartments. In the medical container in which the discharge port is formed, the plurality of compartments are liquid-tightly partitioned by a partitioning means, and the space between the discharge port and the compartment communicating with the discharge port is liquid-tightly closed by a closing means. The partitioning means and the closing means are released by an internal pressure generated by pressing at least a part of the outer surface of the bag body, and the closing means is released by an internal pressure higher than an internal pressure for releasing the partitioning means. It is a medical container characterized by this.
[0008]
At this time, the partitioning means and the closing means are not particularly limited, and a heat seal formed by heating and pressing the inner surface of the bag body made of a thermoplastic resin film, a clip sandwiched from the outer surface of the bag body, and the like. Can be mentioned. As the closing means, a means for covering the discharge port (tube) with a thin film may be used.
[0009]
In addition, the number of compartments is not particularly limited, and may be two or more. When there are three or more compartments, the number of partition means is one less than the number of compartments. Then, any one of the compartments, preferably a compartment far from the discharge port is pressed to release the partitioning means simultaneously or in a chained manner, and finally, the closing means is released by further pressing.
[0010]
(2) a partition means and closure means, heating the inner surface the Judges of the bag body made of a thermoplastic resin film, medical according to (1), characterized in that a heat seal formed by pressing It is a container.
[0011]
(3) Two compartments in which liquid components of different components are separately accommodated in a bag made of a thermoplastic resin film, and a mixed solution of the liquid components of different components communicating with one of the two compartments In the medical container in which the discharge port is formed, the two compartments are partitioned liquid-tight by partition means, and the discharge chamber and the compartment communicating with the discharge port are liquid-tightly closed by closing means. The partitioning means and the closing means are heat seals formed by heating and pressing inner surfaces of the bag made of the thermoplastic resin film, and the heat seal of the closing means is the partition. are bonded with a higher strength than the heat sealing means, heat sealing of the two partition means by adding an internal pressure a in the partition means to press the outer surface of one of the compartments is stripped, and Furthermore, the heat seal of the closing means is peeled off by pressing the bag from the outer surface and applying an internal pressure B higher than the internal pressure A to the closing means.
That is, the heat sealing strength of the closing means is higher than the heat sealing strength of the partitioning means.
[0012]
In the present invention, the thermoplastic resin is not particularly limited, and polyethylene, polypropylene, polyvinyl chloride, ethylene-vinyl acetate copolymer, polyamide, polyvinylidene chloride, polyvinyl fluoride, polytrifluoroethylene, polyethylene terephthalate. , Polyester, polyolefin resin, and mixtures and laminates thereof. Since the medical container of the present invention is preferably manufactured in consideration of hygiene and safety, and then subjected to heat sterilization such as high-pressure steam sterilization or high-frequency sterilization, a material that can withstand these is preferable.
[0013]
In the present invention, the actual measured values of the partitioning means and the closing means are not particularly limited as long as they can be released by being put on a flat surface and pressed with a palm from above. By way of example, the partition means 10 to 100 g / cm ^2, preferably set to be released by adding the internal pressure of 20~60g / cm ^2, 10~70g than the strength of the partition means was set closure / It is set so as to be released by applying an internal pressure of cm ² , preferably 20 to 60 g / cm ² higher.
[0014]
According to the present invention, when a plurality of liquid preparations are mixed with a peritoneal dialysis solution, an intravenous infusion, a liquid nutrient (oral / enteral nutrient), or the like, only the mixed fluid can be discharged reliably.
[0015]
DETAILED DESCRIPTION OF THE INVENTION
The medical instrument of the present invention will be described below with reference to two examples, but is not limited thereto.
An example of the medical container of the present invention will be described with reference to FIGS.
FIG. 1 is a front view of a medical container 1 of the present invention, and FIG. 2 is a cross-sectional view taken along the line I-I 'of FIG.
The medical container 1 is composed of a bag body 2 having one end sealed with a heat seal portion 9 and the other end sealed with a heat seal portion 10 in a sterile state. Further, the partitioning means 4 formed by heat sealing constitutes the compartment 11 and the compartment 12, and the closing means 3 formed by heat sealing is provided near the heat seal portion 9 of the compartment 11. At this time, the space 14 between the closing means 3 and the heat seal portion 9 is aseptic and is preferably as narrow as possible to avoid loss of the capacity of the compartment 11. In some cases, a pharmacologically inert liquid such as physiological saline may be placed between the closing means 3 and the heat seal portion 9 in order to prime a circuit through which the mixed liquid agent passes. A liquid agent 15 is sealed in the compartment 11 and a liquid agent 16 is sealed in the compartment 12 in a sterile state.
[0016]
At this time, the closing means 3 is heat-sealed with a strength higher than that of the partition means 4. Specifically, the closing means is released by applying a pressure (internal pressure B) equal to or higher than the pressure (internal pressure A) applied to the partitioning means. That is, the heat sealing strength of the closing means is set to be equal to or higher than the heat sealing strength of the partitioning means. The adjustment of the heat seal strength is not particularly limited, but can be adjusted by the width and depth of the heat seal portion.
In the present invention, since the internal pressure is a pressure applied to the closing means or the partitioning means, it does not always coincide with the pressure that presses the outer surface of the bag or the compartment.
[0017]
In addition, a discharge pipe 5 is provided at one end so as to be sandwiched by the heat seal portion 9, and an injection pipe 7 having a diameter smaller than that of the discharge pipe 5 is provided at the other end so as to be sandwiched by the heat seal portion 10. The plugs 6 and 8 are respectively sealed. In some cases, the injection tube 7 may not be provided. Moreover, the hole 13 for suspending is provided as needed.
[0018]
Next, the usage method of the medical container 1 is demonstrated. When the closing means 3 is heat-sealed with a strength higher than that of the partitioning means 4 as a method of use, first, by manually pressing the outer surface of the compartment 12, the internal pressure in the compartment 12 caused by the pressure is generated. The heat seal is peeled off, and liquid 15 and liquid 16 are mixed. Further pressed with a strong force, to separate the heat seal closure 3 in the closed unit 3 over a stronger pressure than partitioning means 4. Thereafter, a bottle needle or the like (not shown) is inserted from the stopper 6 and the mixed liquid is discharged.
[0020]
In addition, it is not limited to the usage method mentioned above in particular, A bottle needle etc. may be previously stabbed in the stopper body 6 before releasing a closing means and a partition means. Moreover, the discharge operation can be efficiently performed by suspending through the hole 13 for suspending.
[0021]
Although it does not specifically limit as the liquid 15, the liquid 16, and these liquid mixture, The acidic solution which mix | blended glucose, an amino acid, a peptide, an organic acid, etc. with the other liquid is a basic solution which mix | blended bicarbonate ion etc. Make a solution and mix it into a neutral peritoneal dialysis solution containing bicarbonate, one solution containing a sugar such as glucose, the other solution containing a nitrogen source such as an amino acid, or one solution of water And a solution containing an oil-soluble vitamin in which the solution B is mixed with an oil-soluble vitamin.
[0022]
The medical container 1 is produced by the following method. The liquid 15 and the liquid 16 are aseptically supplied from the discharge pipe 5 and the injection pipe 7 of the container having the same structure as the medical container 1 except that the liquid 15 and the liquid 16 are not filled and the closing means 3 is not formed. After filling the container, the container is stood and fixed so that the discharge pipe 5 faces upward, and the closing means 3 is formed. Further, without providing the injection pipe 7, the container is stood and fixed so that the discharge pipe 5 faces upward, and the liquid agent 16 is aseptically filled from the discharge pipe 5 to form the partition means 4, and then the discharge pipe From 5, the solution 15 is aseptically filled to form the closing means 3. It is not necessary to limit to these methods.
[0023]
The method for forming the heat seal between the closing means 3 and the partition means 4 in the medical container 1 is not particularly limited, and can be performed using a heat seal bar or the like that is normally used. Moreover, you may use the method of producing blocking in the site | part of the closing means 3 and the partition means 4 at the time of heat sterilization, such as high pressure steam sterilization.
[0024]
【The invention's effect】
The medical device of the present invention does not discharge only one liquid agent, such as a peritoneal dialysis liquid, an intravenous infusion liquid agent, and a liquid nutrient, such as a mixture of two or more liquid agents. Each component can be mixed and discharged aseptically by an easy operation.
[Brief description of the drawings]
FIG. 1 is a front view of an example of a medical container of the present invention.
FIG. 2 is a cross-sectional view taken along the line II ′ in FIG.
[Explanation of symbols]
DESCRIPTION OF SYMBOLS 1 ... Medical container 2 ... Bag body 3 ... Closing means 4 ... Partition means 5 ... Drain pipe 6 ... Plug body 7 ... Injection pipe 8 ... Plug body 9 DESCRIPTION OF SYMBOLS 10 ... Heat seal part 11, 12 ... Branch 13 ... Hole 14 for suspending ... Between the closing means 3 and the heat seal part 9, 16, 16 ... Liquid agent

Claims

A bag made of a thermoplastic resin film has a plurality of compartments in which liquid agents of different components are housed, and a discharge port that communicates with one of the plurality of compartments and discharges the liquid mixture of the liquid ingredients of different components. In the formed medical container, the plurality of compartments are partitioned liquid-tight by a partitioning means, and a space between the discharge port and the compartments communicating with the discharge port is liquid-tightly closed by a closing means. The partition unit and the closing unit are released by an internal pressure generated by pressing at least a part of the outer surface of the bag body, and the closing unit is released by an internal pressure higher than an internal pressure for releasing the partition unit. Medical container.

The medical container according to claim 1, wherein the partitioning means and the closing means are heat seals formed by heating and pressing inner surfaces of a bag made of a thermoplastic resin film.

Two compartments in which liquids of different components are separately accommodated in a bag made of a thermoplastic resin film, and a discharge port that communicates with one of the two compartments and discharges the mixed liquid of the different components In the medical container in which is formed, the two compartments are partitioned liquid-tight by a partitioning means, and a space between the discharge port and the compartment communicating with the discharge port is liquid-tightly closed by a closing means, The partition means and the closing means are heat seals formed by heating and pressing inner surfaces of the bag made of the thermoplastic resin film, and the heat seal of the closing means is a heat seal of the partition means. are bonded at a higher seal strength, heat sealing of the two partition means by adding an internal pressure a in the partition means to press the outer surface of one of the compartments is stripped further before Medical container, wherein the heat sealing of the closure means by the bag to press the outer surface applies a pressure B of higher pressure than the internal pressure A to the closing means is peeled.