JP4050329B2 - プロリルピペプチジルアミノペプチダーゼ活性を有するポリペプチド及びそれをコードする核酸 - Google Patents

プロリルピペプチジルアミノペプチダーゼ活性を有するポリペプチド及びそれをコードする核酸 Download PDF

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JP4050329B2
JP4050329B2 JP54941398A JP54941398A JP4050329B2 JP 4050329 B2 JP4050329 B2 JP 4050329B2 JP 54941398 A JP54941398 A JP 54941398A JP 54941398 A JP54941398 A JP 54941398A JP 4050329 B2 JP4050329 B2 JP 4050329B2
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polypeptide
nucleic acid
acid sequence
seq
sequence
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Japanese (ja)
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JP2002511746A (ja
JP2002511746A5 (enExample
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ブリンコフスキー，アレキサンダー
ブラウン，キンバリー
ダブリュ． レイ，マイケル
クロッツ，アラン
バイアン，トニー
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ノボザイムス，インコーポレイテッド
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A—HUMAN NECESSITIES
    • A21—BAKING; EDIBLE DOUGHS
    • A21D—TREATMENT OF FLOUR OR DOUGH FOR BAKING, e.g. BY ADDITION OF MATERIALS; BAKING; BAKERY PRODUCTS
    • A21D2/00—Treatment of flour or dough by adding materials thereto before or during baking
    • A21D2/08—Treatment of flour or dough by adding materials thereto before or during baking by adding organic substances
    • A21D2/24—Organic nitrogen compounds
    • A21D2/26—Proteins
    • A21D2/267—Microbial proteins
    • A—HUMAN NECESSITIES
    • A21—BAKING; EDIBLE DOUGHS
    • A21D—TREATMENT OF FLOUR OR DOUGH FOR BAKING, e.g. BY ADDITION OF MATERIALS; BAKING; BAKERY PRODUCTS
    • A21D8/00—Methods for preparing or baking dough
    • A21D8/02—Methods for preparing dough; Treating dough prior to baking
    • A21D8/04—Methods for preparing dough; Treating dough prior to baking treating dough with microorganisms or enzymes
    • A21D8/042—Methods for preparing dough; Treating dough prior to baking treating dough with microorganisms or enzymes with enzymes
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23J—PROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
    • A23J3/00—Working-up of proteins for foodstuffs
    • A23J3/30—Working-up of proteins for foodstuffs by hydrolysis
    • A23J3/32—Working-up of proteins for foodstuffs by hydrolysis using chemical agents
    • A23J3/34—Working-up of proteins for foodstuffs by hydrolysis using chemical agents using enzymes
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/20—Synthetic spices, flavouring agents or condiments
    • A23L27/21—Synthetic spices, flavouring agents or condiments containing amino acids

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Food Science & Technology (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Nutrition Science (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
JP54941398A 1997-05-16 1998-05-12 プロリルピペプチジルアミノペプチダーゼ活性を有するポリペプチド及びそれをコードする核酸 Expired - Fee Related JP4050329B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US85788497A 1997-05-16 1997-05-16
US08/857,884 1997-05-16
US6289297P 1997-10-20 1997-10-20
US60/062,892 1997-10-20
PCT/US1998/009629 WO1998051803A1 (en) 1997-05-16 1998-05-12 Polypeptides having prolyl pipeptidyl aminopeptidase activity and nucleic acids encoding same

Publications (3)

Publication Number Publication Date
JP2002511746A JP2002511746A (ja) 2002-04-16
JP2002511746A5 JP2002511746A5 (enExample) 2005-12-08
JP4050329B2 true JP4050329B2 (ja) 2008-02-20

Family

ID=26742833

Family Applications (1)

Application Number Title Priority Date Filing Date
JP54941398A Expired - Fee Related JP4050329B2 (ja) 1997-05-16 1998-05-12 プロリルピペプチジルアミノペプチダーゼ活性を有するポリペプチド及びそれをコードする核酸

Country Status (9)

Country Link
US (2) US6664092B1 (enExample)
EP (1) EP0981630B1 (enExample)
JP (1) JP4050329B2 (enExample)
CN (1) CN1227363C (enExample)
AT (1) ATE414775T1 (enExample)
AU (1) AU7381098A (enExample)
DE (1) DE69840230D1 (enExample)
DK (1) DK0981630T3 (enExample)
WO (1) WO1998051803A1 (enExample)

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BR0207889A (pt) 2001-03-19 2004-07-27 Ajinomoto Kk Proteìna, molécula de ácido nucleico codificando a mesma, molécula de ácido nucleico recombinante, hospedeiro de microorganismo transformado, processo para produzir uma aminopeptidase, e , aminopeptidase
US7186540B2 (en) * 2001-12-27 2007-03-06 National Institute of Advanced Indusrtial Science and Technology Thermostable glutaminase and thermostable glutaminase gene
WO2003102195A1 (en) * 2002-06-04 2003-12-11 Dsm Ip Assets B.V. Protein hydrolysate rich in tripeptides
JP4300289B2 (ja) * 2002-08-27 2009-07-22 国立大学法人 岡山大学 加水分解又は脱水縮合酵素、及び当該酵素の生産方法、並びに当該酵素を用いたアミドの合成方法
US20040242566A1 (en) 2003-03-25 2004-12-02 Syrrx, Inc. Dipeptidyl peptidase inhibitors
JP2007511467A (ja) 2003-05-14 2007-05-10 タケダ サン ディエゴ インコーポレイテッド ジペプチジルペプチダーゼインヒビター
UA89616C2 (ru) * 2003-08-01 2010-02-25 Калпис Ко., Лтд. Гидролизат казеина, способ его получения и применения
US7678909B1 (en) 2003-08-13 2010-03-16 Takeda Pharmaceutical Company Limited Dipeptidyl peptidase inhibitors
MXPA06001601A (es) 2003-08-13 2006-08-25 Takeda Pharmaceutical Derivados de 4-pirimidona y su uso como inhibidores de dipeptidilpeptidasa.
US7169926B1 (en) 2003-08-13 2007-01-30 Takeda Pharmaceutical Company Limited Dipeptidyl peptidase inhibitors
WO2005026148A1 (en) 2003-09-08 2005-03-24 Takeda San Diego, Inc. Dipeptidyl peptidase inhibitors
US7732446B1 (en) 2004-03-11 2010-06-08 Takeda Pharmaceutical Company Limited Dipeptidyl peptidase inhibitors
CN102127057A (zh) 2004-03-15 2011-07-20 武田药品工业株式会社 二肽基肽酶抑制剂
WO2005118555A1 (en) 2004-06-04 2005-12-15 Takeda Pharmaceutical Company Limited Dipeptidyl peptidase inhibitors
WO2006019965A2 (en) 2004-07-16 2006-02-23 Takeda San Diego, Inc. Dipeptidyl peptidase inhibitors
EP1828192B1 (en) 2004-12-21 2014-12-03 Takeda Pharmaceutical Company Limited Dipeptidyl peptidase inhibitors
SI1942898T2 (sl) 2005-09-14 2014-08-29 Takeda Pharmaceutical Company Limited Dipeptidil-peptidazni inhibitorji za zdravljenje diabetesa
EP1924567B1 (en) 2005-09-16 2012-08-22 Takeda Pharmaceutical Company Limited Process for the preparation of pyrimidinedione derivatives
WO2007112347A1 (en) 2006-03-28 2007-10-04 Takeda Pharmaceutical Company Limited Dipeptidyl peptidase inhibitors
US8324383B2 (en) 2006-09-13 2012-12-04 Takeda Pharmaceutical Company Limited Methods of making polymorphs of benzoate salt of 2-[[6-[(3R)-3-amino-1-piperidinyl]-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidinyl]methyl]-benzonitrile
TW200838536A (en) 2006-11-29 2008-10-01 Takeda Pharmaceutical Polymorphs of succinate salt of 2-[6-(3-amino-piperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-ylmethy]-4-fluor-benzonitrile and methods of use therefor
US8093236B2 (en) 2007-03-13 2012-01-10 Takeda Pharmaceuticals Company Limited Weekly administration of dipeptidyl peptidase inhibitors
US9493759B2 (en) 2008-12-12 2016-11-15 Novozymes, Inc. Polypeptides having aspartic endopeptidase activity and polynucleotides encoding same
CN102333788A (zh) * 2009-02-19 2012-01-25 诺沃—诺迪斯克有限公司 因子viii的修饰
JP5759132B2 (ja) * 2010-09-21 2015-08-05 月桂冠株式会社 糸状菌ペプチダーゼの生産方法
WO2013092731A1 (en) * 2011-12-21 2013-06-27 Dsm Ip Assets B.V. Method for making a dough with a glutamyl endopeptidase
CN103695361B (zh) * 2013-12-06 2015-11-11 江南大学 一种生产脯氨酸氨肽酶的基因工程菌及其构建方法
GB201705750D0 (en) * 2017-04-10 2017-05-24 Univ Oxford Innovation Ltd Peptide ligase and use therof
EP4273249A3 (en) * 2023-07-07 2024-05-22 Novozymes A/S Improved expression of recombinant proteins

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Also Published As

Publication number Publication date
EP0981630A1 (en) 2000-03-01
DE69840230D1 (de) 2009-01-02
EP0981630B1 (en) 2008-11-19
US6664092B1 (en) 2003-12-16
CN1268976A (zh) 2000-10-04
AU7381098A (en) 1998-12-08
JP2002511746A (ja) 2002-04-16
CN1227363C (zh) 2005-11-16
WO1998051803A1 (en) 1998-11-19
US7098001B2 (en) 2006-08-29
DK0981630T3 (da) 2009-03-09
US20040171104A1 (en) 2004-09-02
ATE414775T1 (de) 2008-12-15

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