JP4005146B2 - リガンド−アミノデキストラン−マーカーコンジュゲート及びその使用 - Google Patents

リガンド−アミノデキストラン−マーカーコンジュゲート及びその使用 Download PDF

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JP4005146B2
JP4005146B2 JP54949998A JP54949998A JP4005146B2 JP 4005146 B2 JP4005146 B2 JP 4005146B2 JP 54949998 A JP54949998 A JP 54949998A JP 54949998 A JP54949998 A JP 54949998A JP 4005146 B2 JP4005146 B2 JP 4005146B2
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aminodextran
conjugate
amdex
phycobiliprotein
ligand
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JP54949998A
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Japanese (ja)
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JP2002504992A (ja
JP2002504992A5 (https=
Inventor
シーマン，オラビ
バーシュテイン，アレキサンダー
ミルバガナル，ラビンドラ
レイナー，ロバート
ロス，パトリシア
スミス，セシリア
ウィルキンソン，ジュリー
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コールター インターナショナル コーポレイション
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Priority claimed from US08/857,941 external-priority patent/US5891741A/en
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G01N33/533—Production of labelled immunochemicals with fluorescent label
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/566—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966—Animal cells
    • G01N33/56977—HLA or MHC typing
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/80—Fluorescent dyes, e.g. rhodamine
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/805—Optical property

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Zoology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
JP54949998A 1997-05-16 1998-05-14 リガンド−アミノデキストラン−マーカーコンジュゲート及びその使用 Expired - Fee Related JP4005146B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US08/857,941 US5891741A (en) 1997-05-16 1997-05-16 Antibody-aminodextran-phycobiliprotein conjugates
US08/857,941 1997-05-16
US08/976,031 1997-11-21
US08/976,031 US5994089A (en) 1997-05-16 1997-11-21 Simultaneous analyses of white blood cell subsets using multi-color, multi-intensity fluorescent markers in flow cytometry
PCT/US1998/009774 WO1998052040A1 (en) 1997-05-16 1998-05-14 Ligand-aminodextran-marker conjugates and uses thereof

Publications (3)

Publication Number Publication Date
JP2002504992A JP2002504992A (ja) 2002-02-12
JP2002504992A5 JP2002504992A5 (https=) 2005-12-02
JP4005146B2 true JP4005146B2 (ja) 2007-11-07

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JP54949998A Expired - Fee Related JP4005146B2 (ja) 1997-05-16 1998-05-14 リガンド−アミノデキストラン−マーカーコンジュゲート及びその使用

Country Status (5)

Country Link
US (2) US5994089A (https=)
EP (1) EP0981747B1 (https=)
JP (1) JP4005146B2 (https=)
DE (1) DE69806925T2 (https=)
WO (1) WO1998052040A1 (https=)

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US10611818B2 (en) 2007-09-27 2020-04-07 Agilent Technologies, Inc. MHC multimers in tuberculosis diagnostics, vaccine and therapeutics
US8266950B2 (en) 2007-12-19 2012-09-18 Los Alamos National Security, LLP Particle analysis in an acoustic cytometer
US8491870B2 (en) 2007-12-21 2013-07-23 Lers Surgical, Llc Method for detection and treatment of aneurysms
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DK2254592T3 (da) 2008-02-28 2019-09-09 Dako Denmark As MHC-multimerer til Borrelia-diagnostik og sygdom
US8679764B2 (en) 2008-03-11 2014-03-25 Becton, Dickinson And Company Density-based cell detection system
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CN101988082B (zh) 2009-07-31 2015-04-08 深圳迈瑞生物医疗电子股份有限公司 白细胞分类计数试剂、试剂盒及其制备方法和白细胞分类计数的方法
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CN103229057B (zh) * 2010-09-23 2016-08-10 生物概念股份有限公司 用于信号放大的方法和试剂
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JP6752231B2 (ja) 2015-06-01 2020-09-09 カリフォルニア インスティテュート オブ テクノロジー 抗原を用いて特異的集団に関してｔ細胞をスクリーニングするための組成物および方法
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Publication number Publication date
JP2002504992A (ja) 2002-02-12
EP0981747A1 (en) 2000-03-01
US6387622B1 (en) 2002-05-14
US5994089A (en) 1999-11-30
DE69806925T2 (de) 2003-02-27
WO1998052040A1 (en) 1998-11-19
DE69806925D1 (de) 2002-09-05
EP0981747B1 (en) 2002-07-31

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