JP3948495B2 - 喘息および関連疾患を含むアトピー性アレルギーを治療するための標的としての喘息関連因子 - Google Patents

喘息および関連疾患を含むアトピー性アレルギーを治療するための標的としての喘息関連因子 Download PDF

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JP3948495B2
JP3948495B2 JP51028397A JP51028397A JP3948495B2 JP 3948495 B2 JP3948495 B2 JP 3948495B2 JP 51028397 A JP51028397 A JP 51028397A JP 51028397 A JP51028397 A JP 51028397A JP 3948495 B2 JP3948495 B2 JP 3948495B2
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sequence
receptor
seq
dna
asthma
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JPH11514851A5 (enExample
JPH11514851A (ja
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ロイ クリフォード レビット
メロー タブリュ. リー
カール ユー. プラサド
ニコレイデズ ニコラス
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ジェネーラ コーポレーション
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/145Amines having sulfur, e.g. thiurams (>N—C(S)—S—C(S)—N< and >N—C(S)—S—S—C(S)—N<), Sulfinylamines (—N=SO), Sulfonylamines (—N=SO2)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/54Interleukins [IL]
    • C07K14/5425IL-9
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7155Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for interleukins [IL]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244Interleukins [IL]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
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  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
JP51028397A 1995-08-24 1996-08-23 喘息および関連疾患を含むアトピー性アレルギーを治療するための標的としての喘息関連因子 Expired - Fee Related JP3948495B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US276595P 1995-08-24 1995-08-24
US60/002,765 1995-08-24
US2380096P 1996-08-06 1996-08-06
US60/023,800 1996-08-06
PCT/US1996/012757 WO1997008321A1 (en) 1995-08-24 1996-08-23 Asthma associated factors as targets for treating atopic allergies including asthma and related disorders

Related Child Applications (1)

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JP2007001870A Division JP4813380B2 (ja) 1995-08-24 2007-01-09 喘息および関連疾患を含むアトピー性アレルギーを治療するための標的としての喘息関連因子

Publications (3)

Publication Number Publication Date
JPH11514851A JPH11514851A (ja) 1999-12-21
JPH11514851A5 JPH11514851A5 (enExample) 2004-09-09
JP3948495B2 true JP3948495B2 (ja) 2007-07-25

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Family Applications (3)

Application Number Title Priority Date Filing Date
JP51028397A Expired - Fee Related JP3948495B2 (ja) 1995-08-24 1996-08-23 喘息および関連疾患を含むアトピー性アレルギーを治療するための標的としての喘息関連因子
JP2007001870A Expired - Fee Related JP4813380B2 (ja) 1995-08-24 2007-01-09 喘息および関連疾患を含むアトピー性アレルギーを治療するための標的としての喘息関連因子
JP2011043283A Withdrawn JP2011152135A (ja) 1995-08-24 2011-02-28 喘息および関連疾患を含むアトピー性アレルギーを治療するための標的としての喘息関連因子

Family Applications After (2)

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JP2007001870A Expired - Fee Related JP4813380B2 (ja) 1995-08-24 2007-01-09 喘息および関連疾患を含むアトピー性アレルギーを治療するための標的としての喘息関連因子
JP2011043283A Withdrawn JP2011152135A (ja) 1995-08-24 2011-02-28 喘息および関連疾患を含むアトピー性アレルギーを治療するための標的としての喘息関連因子

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EP (3) EP1632248B8 (enExample)
JP (3) JP3948495B2 (enExample)
AT (2) ATE484294T1 (enExample)
AU (1) AU6895696A (enExample)
CA (2) CA2666298A1 (enExample)
DE (2) DE69635305T2 (enExample)
DK (2) DK1632248T3 (enExample)
ES (2) ES2249786T3 (enExample)
PT (1) PT1632248E (enExample)
WO (1) WO1997008321A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002514911A (ja) * 1996-12-02 2002-05-21 ジェネーラ コーポレーション 喘息および関連疾患を含むアトピー性アレルギーの治療および診断に有用なil−9受容体変異体

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5830454A (en) * 1996-08-30 1998-11-03 Ludwig Institute For Cancer Research Method for treating cell mediated autoimmune disorders using interleukin-9
CA2689842A1 (en) * 1996-12-02 1998-06-11 Genaera Corporation Il-9 receptor variants, useful in treating and diagnosing atopic allergies including asthma and related disorders
WO1998027997A1 (en) * 1996-12-20 1998-07-02 Magainin Pharmaceuticals Inc. A method for diagnosis and treatment of inflammatory bowel diseases including crohn's disease and chronic ulcerative colitis
CA2302782A1 (en) * 1997-09-19 1999-03-25 Magainin Pharmaceuticals, Inc. Asthma associated factors as targets for treating atopic allergies including asthma and related disorders
JP2001517682A (ja) * 1997-09-19 2001-10-09 マガイニン ファーマシューティカルズ インク. 喘息および関連疾患を含むアトピー性アレルギーを治療するための標的としての喘息関連因子
EP1181037A4 (en) * 1999-05-01 2006-01-18 Genaera Corp FACTORS ASSOCIATED WITH ASTHMA AS TARGETS FOR TREATING ATOPIC ALLERGIES, ESPECIALLY ASTHMA AND RELATED DISORDERS
AU2001238079A1 (en) * 2000-02-09 2001-08-20 Med Immune, Inc. Antibody gene therapy with adeno-associated viral vectors
WO2002068594A2 (en) * 2001-02-22 2002-09-06 The Research Foundation Of State University Of New York Opiate receptors
EP1401497B1 (en) 2001-06-08 2012-01-11 Genaera Corporation Methods for the modulation of il-13
AU2004229527B2 (en) * 2003-04-11 2009-08-20 Medimmune, Llc Methods of preventing or treating respiratory conditions
EP1771565B1 (en) 2004-07-20 2012-09-05 The Feinstein Institute for Medical Research Rage protein derivatives
US7635754B2 (en) * 2004-09-22 2009-12-22 Aerovance, Inc. Interleukin-9 and interleukin-4 chimeric antagonist muteins and methods of using same
EP2364998A1 (en) 2005-06-16 2011-09-14 The Feinstein Institute for Medical Research Antibodies against HMGB1 and fragments thereof
US8133859B2 (en) 2006-09-27 2012-03-13 The United States Of America As Represented By The Department Of Health And Human Services SCGB3A2 as a growth factor and anti-apoptotic agent
JP5564167B2 (ja) * 2008-05-22 2014-07-30 日本たばこ産業株式会社 苦味マスキング剤及び苦味低減方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5208218A (en) * 1988-09-19 1993-05-04 Ludwig Institute For Cancer Research T cell growth factor glycoproteins
US5414071A (en) 1989-05-23 1995-05-09 Genetics Institute, Inc. Human cytokine IL-9
US5132109A (en) * 1990-10-05 1992-07-21 Ludwig Institute For Cancer Research Method for inhibiting production of ige and method for enhancing production of igg using interleukin 9 and inhibitors thereof
JPH09511400A (ja) 1994-03-30 1997-11-18 ユニバーシティ オブ メリーランド アット ボルティモア 交互スプライシングによって生成されるヒトインターロイキン変異体

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002514911A (ja) * 1996-12-02 2002-05-21 ジェネーラ コーポレーション 喘息および関連疾患を含むアトピー性アレルギーの治療および診断に有用なil−9受容体変異体

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Publication number Publication date
CA2230240C (en) 2009-08-18
JP4813380B2 (ja) 2011-11-09
EP1632248B8 (en) 2010-12-29
PT1632248E (pt) 2010-12-28
DE69635305D1 (de) 2006-03-02
DE69635305T2 (de) 2006-07-06
EP1632248B1 (en) 2010-10-13
EP2241329A3 (en) 2011-03-09
CA2666298A1 (en) 1997-03-06
EP0846173A1 (en) 1998-06-10
ATE307203T1 (de) 2005-11-15
JP2007169287A (ja) 2007-07-05
JP2011152135A (ja) 2011-08-11
JPH11514851A (ja) 1999-12-21
ATE484294T1 (de) 2010-10-15
CA2230240A1 (en) 1997-03-06
DK1632248T3 (da) 2011-01-24
AU6895696A (en) 1997-03-19
EP1632248A1 (en) 2006-03-08
EP0846173B1 (en) 2005-10-19
ES2249786T3 (es) 2006-04-01
EP2241329A2 (en) 2010-10-20
DE69638281D1 (de) 2010-11-25
DK0846173T3 (da) 2006-01-16
ES2354360T3 (es) 2011-03-14
WO1997008321A1 (en) 1997-03-06

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