ES2354360T3 - Anticuerpo anti-interleucina-9 o anticuerpo del receptor anti-interleucina-9 para el tratamiento de la hiperreactividad bronquial. - Google Patents
Anticuerpo anti-interleucina-9 o anticuerpo del receptor anti-interleucina-9 para el tratamiento de la hiperreactividad bronquial. Download PDFInfo
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- ES2354360T3 ES2354360T3 ES05009688T ES05009688T ES2354360T3 ES 2354360 T3 ES2354360 T3 ES 2354360T3 ES 05009688 T ES05009688 T ES 05009688T ES 05009688 T ES05009688 T ES 05009688T ES 2354360 T3 ES2354360 T3 ES 2354360T3
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- 210000003437 trachea Anatomy 0.000 description 1
- 238000010361 transduction Methods 0.000 description 1
- 230000026683 transduction Effects 0.000 description 1
- 238000006276 transfer reaction Methods 0.000 description 1
- 238000000844 transformation Methods 0.000 description 1
- 238000013519 translation Methods 0.000 description 1
- 238000002054 transplantation Methods 0.000 description 1
- 238000011269 treatment regimen Methods 0.000 description 1
- 229910052721 tungsten Inorganic materials 0.000 description 1
- 239000005483 tyrosine kinase inhibitor Substances 0.000 description 1
- DRTQHJPVMGBUCF-UHFFFAOYSA-N uracil arabinoside Natural products OC1C(O)C(CO)OC1N1C(=O)NC(=O)C=C1 DRTQHJPVMGBUCF-UHFFFAOYSA-N 0.000 description 1
- 229940045145 uridine Drugs 0.000 description 1
- 235000013311 vegetables Nutrition 0.000 description 1
- 210000001631 vena cava inferior Anatomy 0.000 description 1
- 230000009385 viral infection Effects 0.000 description 1
- NLIVDORGVGAOOJ-MAHBNPEESA-M xylene cyanol Chemical compound [Na+].C1=C(C)C(NCC)=CC=C1C(\C=1C(=CC(OS([O-])=O)=CC=1)OS([O-])=O)=C\1C=C(C)\C(=[NH+]/CC)\C=C/1 NLIVDORGVGAOOJ-MAHBNPEESA-M 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/145—Amines having sulfur, e.g. thiurams (>N—C(S)—S—C(S)—N< and >N—C(S)—S—S—C(S)—N<), Sulfinylamines (—N=SO), Sulfonylamines (—N=SO2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- C07K14/5425—IL-9
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
- C07K14/7155—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for interleukins [IL]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/244—Interleukins [IL]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Pulmonology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Gastroenterology & Hepatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Cell Biology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US276595P | 1995-08-24 | 1995-08-24 | |
| US2765P | 1995-08-24 | ||
| US2380096P | 1996-08-06 | 1996-08-06 | |
| US23800P | 1996-08-06 | ||
| EP96929657A EP0846173B1 (en) | 1995-08-24 | 1996-08-23 | Use of an anti-interleukin-9 antibody for the preparation of a medicament for the treatment of asthma |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2354360T3 true ES2354360T3 (es) | 2011-03-14 |
Family
ID=26670837
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES05009688T Expired - Lifetime ES2354360T3 (es) | 1995-08-24 | 1996-08-23 | Anticuerpo anti-interleucina-9 o anticuerpo del receptor anti-interleucina-9 para el tratamiento de la hiperreactividad bronquial. |
| ES96929657T Expired - Lifetime ES2249786T3 (es) | 1995-08-24 | 1996-08-23 | Uso de un anticuerpo antiinterleuquina 9 para la preparacion de un medicamento para el tratamiento de asma. |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES96929657T Expired - Lifetime ES2249786T3 (es) | 1995-08-24 | 1996-08-23 | Uso de un anticuerpo antiinterleuquina 9 para la preparacion de un medicamento para el tratamiento de asma. |
Country Status (10)
| Country | Link |
|---|---|
| EP (3) | EP1632248B8 (enExample) |
| JP (3) | JP3948495B2 (enExample) |
| AT (2) | ATE484294T1 (enExample) |
| AU (1) | AU6895696A (enExample) |
| CA (2) | CA2230240C (enExample) |
| DE (2) | DE69635305T2 (enExample) |
| DK (2) | DK1632248T3 (enExample) |
| ES (2) | ES2354360T3 (enExample) |
| PT (1) | PT1632248E (enExample) |
| WO (1) | WO1997008321A1 (enExample) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5830454A (en) * | 1996-08-30 | 1998-11-03 | Ludwig Institute For Cancer Research | Method for treating cell mediated autoimmune disorders using interleukin-9 |
| EP1471144B1 (en) * | 1996-12-02 | 2010-06-23 | Genaera Corporation | Biological variability of asthma associated factor AAF2 (IL-9 receptor) useful in treating and diagnosing atopic allergies including asthma and related disorders |
| DE69739920D1 (de) * | 1996-12-02 | 2010-08-05 | Genaera Corp | Biologische Variabilität von Asthma-assoziiertem Faktor 2 AAF2 (IL-9 Rezeptor) nützlich für die Behandlung und Diagnose von atopischen Allergien wie Asthma und Asthma-ähnlichen Erkrankungen |
| AU5532098A (en) * | 1996-12-20 | 1998-07-17 | Magainin Pharmaceuticals, Inc. | A method for diagnosis and treatment of inflammatory bowel diseases including crohn's disease and chronic ulcerative colitis |
| WO1999015656A2 (en) * | 1997-09-19 | 1999-04-01 | Magainin Pharmaceuticals Inc. | Asthma associated factors as targets for treating atopic allergies including asthma and related disorders |
| CA2302782A1 (en) * | 1997-09-19 | 1999-03-25 | Magainin Pharmaceuticals, Inc. | Asthma associated factors as targets for treating atopic allergies including asthma and related disorders |
| EP1181037A4 (en) * | 1999-05-01 | 2006-01-18 | Genaera Corp | FACTORS ASSOCIATED WITH ASTHMA AS TARGETS FOR TREATING ATOPIC ALLERGIES, ESPECIALLY ASTHMA AND RELATED DISORDERS |
| WO2002100432A1 (en) | 2001-06-08 | 2002-12-19 | Genaera Corporation | Methods for the modulation of il-13 |
| WO2001059142A1 (en) * | 2000-02-09 | 2001-08-16 | Medimmune, Inc. | Antibody gene therapy with adeno-associated viral vectors |
| CA2439175C (en) * | 2001-02-22 | 2014-05-06 | The Research Foundation Of State University Of New York | Opiate receptors |
| WO2004091519A2 (en) * | 2003-04-11 | 2004-10-28 | Medimmune, Inc. | Methods of preventing or treating respiratory conditions |
| EP1771565B1 (en) | 2004-07-20 | 2012-09-05 | The Feinstein Institute for Medical Research | Rage protein derivatives |
| US7635754B2 (en) * | 2004-09-22 | 2009-12-22 | Aerovance, Inc. | Interleukin-9 and interleukin-4 chimeric antagonist muteins and methods of using same |
| EP2364998A1 (en) | 2005-06-16 | 2011-09-14 | The Feinstein Institute for Medical Research | Antibodies against HMGB1 and fragments thereof |
| WO2008039941A2 (en) | 2006-09-27 | 2008-04-03 | The Government Of The Usa As Represented By The Secretary Of The Dpt. Of Health And Human Services | Scgb3a2 as a growth factor and anti-apoptotic agent |
| JP5564167B2 (ja) * | 2008-05-22 | 2014-07-30 | 日本たばこ産業株式会社 | 苦味マスキング剤及び苦味低減方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5208218A (en) * | 1988-09-19 | 1993-05-04 | Ludwig Institute For Cancer Research | T cell growth factor glycoproteins |
| US5414071A (en) | 1989-05-23 | 1995-05-09 | Genetics Institute, Inc. | Human cytokine IL-9 |
| US5132109A (en) * | 1990-10-05 | 1992-07-21 | Ludwig Institute For Cancer Research | Method for inhibiting production of ige and method for enhancing production of igg using interleukin 9 and inhibitors thereof |
| CA2186854A1 (en) | 1994-03-30 | 1995-10-12 | William J. Alms | Human interleukin variants generated by alternative splicing |
-
1996
- 1996-08-23 DK DK05009688.2T patent/DK1632248T3/da active
- 1996-08-23 CA CA002230240A patent/CA2230240C/en not_active Expired - Lifetime
- 1996-08-23 ES ES05009688T patent/ES2354360T3/es not_active Expired - Lifetime
- 1996-08-23 ES ES96929657T patent/ES2249786T3/es not_active Expired - Lifetime
- 1996-08-23 EP EP05009688A patent/EP1632248B8/en not_active Expired - Lifetime
- 1996-08-23 PT PT05009688T patent/PT1632248E/pt unknown
- 1996-08-23 JP JP51028397A patent/JP3948495B2/ja not_active Expired - Fee Related
- 1996-08-23 EP EP10004496A patent/EP2241329A3/en not_active Withdrawn
- 1996-08-23 AU AU68956/96A patent/AU6895696A/en not_active Abandoned
- 1996-08-23 AT AT05009688T patent/ATE484294T1/de active
- 1996-08-23 DE DE69635305T patent/DE69635305T2/de not_active Expired - Lifetime
- 1996-08-23 CA CA002666298A patent/CA2666298A1/en not_active Abandoned
- 1996-08-23 EP EP96929657A patent/EP0846173B1/en not_active Expired - Lifetime
- 1996-08-23 DK DK96929657T patent/DK0846173T3/da active
- 1996-08-23 AT AT96929657T patent/ATE307203T1/de active
- 1996-08-23 DE DE69638281T patent/DE69638281D1/de not_active Expired - Lifetime
- 1996-08-23 WO PCT/US1996/012757 patent/WO1997008321A1/en not_active Ceased
-
2007
- 2007-01-09 JP JP2007001870A patent/JP4813380B2/ja not_active Expired - Fee Related
-
2011
- 2011-02-28 JP JP2011043283A patent/JP2011152135A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| AU6895696A (en) | 1997-03-19 |
| EP2241329A3 (en) | 2011-03-09 |
| WO1997008321A1 (en) | 1997-03-06 |
| EP0846173A1 (en) | 1998-06-10 |
| EP1632248A1 (en) | 2006-03-08 |
| DE69635305D1 (de) | 2006-03-02 |
| EP1632248B8 (en) | 2010-12-29 |
| PT1632248E (pt) | 2010-12-28 |
| JPH11514851A (ja) | 1999-12-21 |
| ATE307203T1 (de) | 2005-11-15 |
| JP2007169287A (ja) | 2007-07-05 |
| CA2230240A1 (en) | 1997-03-06 |
| DE69638281D1 (de) | 2010-11-25 |
| DE69635305T2 (de) | 2006-07-06 |
| CA2230240C (en) | 2009-08-18 |
| JP3948495B2 (ja) | 2007-07-25 |
| EP2241329A2 (en) | 2010-10-20 |
| JP2011152135A (ja) | 2011-08-11 |
| CA2666298A1 (en) | 1997-03-06 |
| ES2249786T3 (es) | 2006-04-01 |
| EP0846173B1 (en) | 2005-10-19 |
| ATE484294T1 (de) | 2010-10-15 |
| DK1632248T3 (da) | 2011-01-24 |
| JP4813380B2 (ja) | 2011-11-09 |
| DK0846173T3 (da) | 2006-01-16 |
| EP1632248B1 (en) | 2010-10-13 |
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