JP3947356B2 - 微小球含有センサー - Google Patents
微小球含有センサー Download PDFInfo
- Publication number
- JP3947356B2 JP3947356B2 JP2000390466A JP2000390466A JP3947356B2 JP 3947356 B2 JP3947356 B2 JP 3947356B2 JP 2000390466 A JP2000390466 A JP 2000390466A JP 2000390466 A JP2000390466 A JP 2000390466A JP 3947356 B2 JP3947356 B2 JP 3947356B2
- Authority
- JP
- Japan
- Prior art keywords
- microspheres
- sample
- powder
- sensor strip
- electrode
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 239000004005 microsphere Substances 0.000 title claims description 64
- 239000003153 chemical reaction reagent Substances 0.000 claims description 33
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims description 25
- 239000000843 powder Substances 0.000 claims description 25
- 239000011324 bead Substances 0.000 claims description 15
- 239000000203 mixture Substances 0.000 claims description 14
- 239000011521 glass Substances 0.000 claims description 11
- 229920000642 polymer Polymers 0.000 claims description 10
- 239000000377 silicon dioxide Substances 0.000 claims description 10
- -1 polyethylene Polymers 0.000 claims description 8
- 238000000034 method Methods 0.000 claims description 7
- 239000004698 Polyethylene Substances 0.000 claims description 6
- 229920000573 polyethylene Polymers 0.000 claims description 6
- GWEVSGVZZGPLCZ-UHFFFAOYSA-N Titan oxide Chemical compound O=[Ti]=O GWEVSGVZZGPLCZ-UHFFFAOYSA-N 0.000 claims description 5
- PNEYBMLMFCGWSK-UHFFFAOYSA-N aluminium oxide Inorganic materials [O-2].[O-2].[O-2].[Al+3].[Al+3] PNEYBMLMFCGWSK-UHFFFAOYSA-N 0.000 claims description 5
- 229910003460 diamond Inorganic materials 0.000 claims description 5
- 239000010432 diamond Substances 0.000 claims description 5
- 229910021485 fumed silica Inorganic materials 0.000 claims description 5
- 239000004816 latex Substances 0.000 claims description 5
- 229920000126 latex Polymers 0.000 claims description 5
- 239000002557 mineral fiber Substances 0.000 claims description 5
- 239000002245 particle Substances 0.000 claims description 5
- OGIDPMRJRNCKJF-UHFFFAOYSA-N titanium oxide Inorganic materials [Ti]=O OGIDPMRJRNCKJF-UHFFFAOYSA-N 0.000 claims description 5
- 239000002923 metal particle Substances 0.000 claims description 4
- 229910052751 metal Inorganic materials 0.000 claims description 3
- 239000002184 metal Substances 0.000 claims description 3
- 238000004519 manufacturing process Methods 0.000 claims description 2
- 239000011248 coating agent Substances 0.000 claims 2
- 238000000576 coating method Methods 0.000 claims 2
- 239000006185 dispersion Substances 0.000 claims 1
- 239000000523 sample Substances 0.000 description 35
- 239000002390 adhesive tape Substances 0.000 description 6
- 108090000790 Enzymes Proteins 0.000 description 5
- 102000004190 Enzymes Human genes 0.000 description 5
- 238000004458 analytical method Methods 0.000 description 5
- 239000007788 liquid Substances 0.000 description 5
- 239000000463 material Substances 0.000 description 5
- 239000000758 substrate Substances 0.000 description 5
- 239000000853 adhesive Substances 0.000 description 4
- 230000001070 adhesive effect Effects 0.000 description 4
- 239000012491 analyte Substances 0.000 description 4
- 239000011888 foil Substances 0.000 description 4
- AWDBHOZBRXWRKS-UHFFFAOYSA-N tetrapotassium;iron(6+);hexacyanide Chemical compound [K+].[K+].[K+].[K+].[Fe+6].N#[C-].N#[C-].N#[C-].N#[C-].N#[C-].N#[C-] AWDBHOZBRXWRKS-UHFFFAOYSA-N 0.000 description 4
- LWIHDJKSTIGBAC-UHFFFAOYSA-K tripotassium phosphate Chemical compound [K+].[K+].[K+].[O-]P([O-])([O-])=O LWIHDJKSTIGBAC-UHFFFAOYSA-K 0.000 description 4
- 239000008280 blood Substances 0.000 description 3
- 210000004369 blood Anatomy 0.000 description 3
- 238000005534 hematocrit Methods 0.000 description 3
- KDLHZDBZIXYQEI-UHFFFAOYSA-N Palladium Chemical compound [Pd] KDLHZDBZIXYQEI-UHFFFAOYSA-N 0.000 description 2
- 239000000956 alloy Substances 0.000 description 2
- 229910045601 alloy Inorganic materials 0.000 description 2
- 238000003556 assay Methods 0.000 description 2
- 239000012472 biological sample Substances 0.000 description 2
- YAGKRVSRTSUGEY-UHFFFAOYSA-N ferricyanide Chemical compound [Fe+3].N#[C-].N#[C-].N#[C-].N#[C-].N#[C-].N#[C-] YAGKRVSRTSUGEY-UHFFFAOYSA-N 0.000 description 2
- 108010054770 glucose dehydrogenase (pyrroloquinoline-quinone) Proteins 0.000 description 2
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 2
- 230000002209 hydrophobic effect Effects 0.000 description 2
- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 description 2
- 229920000728 polyester Polymers 0.000 description 2
- 229910000160 potassium phosphate Inorganic materials 0.000 description 2
- 235000011009 potassium phosphates Nutrition 0.000 description 2
- HDTRYLNUVZCQOY-UHFFFAOYSA-N α-D-glucopyranosyl-α-D-glucopyranoside Natural products OC1C(O)C(O)C(CO)OC1OC1C(O)C(O)C(O)C(CO)O1 HDTRYLNUVZCQOY-UHFFFAOYSA-N 0.000 description 1
- 108010006591 Apoenzymes Proteins 0.000 description 1
- 235000018185 Betula X alpestris Nutrition 0.000 description 1
- 235000018212 Betula X uliginosa Nutrition 0.000 description 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- 229920000663 Hydroxyethyl cellulose Polymers 0.000 description 1
- 229920000168 Microcrystalline cellulose Polymers 0.000 description 1
- 229920003171 Poly (ethylene oxide) Polymers 0.000 description 1
- 239000004642 Polyimide Substances 0.000 description 1
- 239000004743 Polypropylene Substances 0.000 description 1
- HDTRYLNUVZCQOY-WSWWMNSNSA-N Trehalose Natural products O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@H](O)[C@@H](O)[C@@H](O)[C@@H](CO)O1 HDTRYLNUVZCQOY-WSWWMNSNSA-N 0.000 description 1
- 238000002679 ablation Methods 0.000 description 1
- DPXJVFZANSGRMM-UHFFFAOYSA-N acetic acid;2,3,4,5,6-pentahydroxyhexanal;sodium Chemical compound [Na].CC(O)=O.OCC(O)C(O)C(O)C(O)C=O DPXJVFZANSGRMM-UHFFFAOYSA-N 0.000 description 1
- HDTRYLNUVZCQOY-LIZSDCNHSA-N alpha,alpha-trehalose Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 HDTRYLNUVZCQOY-LIZSDCNHSA-N 0.000 description 1
- 210000001124 body fluid Anatomy 0.000 description 1
- 239000010839 body fluid Substances 0.000 description 1
- QXJJQWWVWRCVQT-UHFFFAOYSA-K calcium;sodium;phosphate Chemical compound [Na+].[Ca+2].[O-]P([O-])([O-])=O QXJJQWWVWRCVQT-UHFFFAOYSA-K 0.000 description 1
- 239000001768 carboxy methyl cellulose Substances 0.000 description 1
- 239000000919 ceramic Substances 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 239000007809 chemical reaction catalyst Substances 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 229940111685 dibasic potassium phosphate Drugs 0.000 description 1
- 238000009792 diffusion process Methods 0.000 description 1
- ZPWVASYFFYYZEW-UHFFFAOYSA-L dipotassium hydrogen phosphate Chemical compound [K+].[K+].OP([O-])([O-])=O ZPWVASYFFYYZEW-UHFFFAOYSA-L 0.000 description 1
- 238000004090 dissolution Methods 0.000 description 1
- 238000009826 distribution Methods 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000000840 electrochemical analysis Methods 0.000 description 1
- 238000007812 electrochemical assay Methods 0.000 description 1
- 239000003792 electrolyte Substances 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 239000004744 fabric Substances 0.000 description 1
- 239000000945 filler Substances 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- 229910052737 gold Inorganic materials 0.000 description 1
- 239000010931 gold Substances 0.000 description 1
- 239000010439 graphite Substances 0.000 description 1
- 229910002804 graphite Inorganic materials 0.000 description 1
- 230000036571 hydration Effects 0.000 description 1
- 238000006703 hydration reaction Methods 0.000 description 1
- 230000005660 hydrophilic surface Effects 0.000 description 1
- 230000005661 hydrophobic surface Effects 0.000 description 1
- 235000019447 hydroxyethyl cellulose Nutrition 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 239000011810 insulating material Substances 0.000 description 1
- 229910052741 iridium Inorganic materials 0.000 description 1
- GKOZUEZYRPOHIO-UHFFFAOYSA-N iridium atom Chemical compound [Ir] GKOZUEZYRPOHIO-UHFFFAOYSA-N 0.000 description 1
- 230000001788 irregular Effects 0.000 description 1
- 238000003475 lamination Methods 0.000 description 1
- 238000001459 lithography Methods 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- 239000011159 matrix material Substances 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 150000002739 metals Chemical class 0.000 description 1
- 235000019813 microcrystalline cellulose Nutrition 0.000 description 1
- 239000008108 microcrystalline cellulose Substances 0.000 description 1
- 229940016286 microcrystalline cellulose Drugs 0.000 description 1
- 239000013080 microcrystalline material Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 229910000510 noble metal Inorganic materials 0.000 description 1
- 239000003960 organic solvent Substances 0.000 description 1
- 229910052763 palladium Inorganic materials 0.000 description 1
- 229910052697 platinum Inorganic materials 0.000 description 1
- 229920001721 polyimide Polymers 0.000 description 1
- 229920001155 polypropylene Polymers 0.000 description 1
- 229920000915 polyvinyl chloride Polymers 0.000 description 1
- 239000004800 polyvinyl chloride Substances 0.000 description 1
- 239000008057 potassium phosphate buffer Substances 0.000 description 1
- MMXZSJMASHPLLR-UHFFFAOYSA-N pyrroloquinoline quinone Chemical compound C12=C(C(O)=O)C=C(C(O)=O)N=C2C(=O)C(=O)C2=C1NC(C(=O)O)=C2 MMXZSJMASHPLLR-UHFFFAOYSA-N 0.000 description 1
- 239000000376 reactant Substances 0.000 description 1
- 230000027756 respiratory electron transport chain Effects 0.000 description 1
- 230000002441 reversible effect Effects 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- 235000019812 sodium carboxymethyl cellulose Nutrition 0.000 description 1
- 229940074404 sodium succinate Drugs 0.000 description 1
- ZDQYSKICYIVCPN-UHFFFAOYSA-L sodium succinate (anhydrous) Chemical compound [Na+].[Na+].[O-]C(=O)CCC([O-])=O ZDQYSKICYIVCPN-UHFFFAOYSA-L 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 238000004381 surface treatment Methods 0.000 description 1
- 239000004094 surface-active agent Substances 0.000 description 1
- 239000012780 transparent material Substances 0.000 description 1
- GPRLSGONYQIRFK-MNYXATJNSA-N triton Chemical compound [3H+] GPRLSGONYQIRFK-MNYXATJNSA-N 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Images
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/28—Electrolytic cell components
- G01N27/30—Electrodes, e.g. test electrodes; Half-cells
- G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
- G01N27/3271—Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood
- G01N27/3272—Test elements therefor, i.e. disposable laminated substrates with electrodes, reagent and channels
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Hematology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Electrochemistry (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Investigating Or Analyzing Materials By The Use Of Fluid Adsorption Or Reactions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/471,571 US6627057B1 (en) | 1999-12-23 | 1999-12-23 | Microsphere containing sensor |
US09/471571 | 1999-12-23 |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2001208716A JP2001208716A (ja) | 2001-08-03 |
JP3947356B2 true JP3947356B2 (ja) | 2007-07-18 |
Family
ID=23872134
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2000390466A Expired - Fee Related JP3947356B2 (ja) | 1999-12-23 | 2000-12-22 | 微小球含有センサー |
Country Status (4)
Country | Link |
---|---|
US (1) | US6627057B1 (de) |
EP (1) | EP1113263A3 (de) |
JP (1) | JP3947356B2 (de) |
CA (1) | CA2328751C (de) |
Families Citing this family (40)
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US8071384B2 (en) | 1997-12-22 | 2011-12-06 | Roche Diagnostics Operations, Inc. | Control and calibration solutions and methods for their use |
US20050103624A1 (en) | 1999-10-04 | 2005-05-19 | Bhullar Raghbir S. | Biosensor and method of making |
ATE316651T1 (de) * | 1999-11-15 | 2006-02-15 | Arkray Inc | Biosensor |
AU2002210940A1 (en) * | 2000-10-27 | 2002-05-06 | Arkray, Inc. | Biosensor |
US7758744B2 (en) | 2001-10-05 | 2010-07-20 | Stephen Eliot Zweig | Dual glucose-turbidimetric analytical sensors |
US6984307B2 (en) * | 2001-10-05 | 2006-01-10 | Stephen Eliot Zweig | Dual glucose-hydroxybutyrate analytical sensors |
US6755949B1 (en) * | 2001-10-09 | 2004-06-29 | Roche Diagnostics Corporation | Biosensor |
CN1467496A (zh) * | 2002-06-03 | 2004-01-14 | 松下电器产业株式会社 | 生物传感器 |
US8058077B2 (en) | 2003-06-20 | 2011-11-15 | Roche Diagnostics Operations, Inc. | Method for coding information on a biosensor test strip |
US8679853B2 (en) | 2003-06-20 | 2014-03-25 | Roche Diagnostics Operations, Inc. | Biosensor with laser-sealed capillary space and method of making |
US7645421B2 (en) | 2003-06-20 | 2010-01-12 | Roche Diagnostics Operations, Inc. | System and method for coding information on a biosensor test strip |
US8071030B2 (en) | 2003-06-20 | 2011-12-06 | Roche Diagnostics Operations, Inc. | Test strip with flared sample receiving chamber |
US7645373B2 (en) | 2003-06-20 | 2010-01-12 | Roche Diagnostic Operations, Inc. | System and method for coding information on a biosensor test strip |
US7718439B2 (en) | 2003-06-20 | 2010-05-18 | Roche Diagnostics Operations, Inc. | System and method for coding information on a biosensor test strip |
HUE039852T2 (hu) | 2003-06-20 | 2019-02-28 | Hoffmann La Roche | Eljárás és reagens keskeny, homogén reagenscsíkok elõállítására |
US7452457B2 (en) | 2003-06-20 | 2008-11-18 | Roche Diagnostics Operations, Inc. | System and method for analyte measurement using dose sufficiency electrodes |
US8148164B2 (en) | 2003-06-20 | 2012-04-03 | Roche Diagnostics Operations, Inc. | System and method for determining the concentration of an analyte in a sample fluid |
US7488601B2 (en) | 2003-06-20 | 2009-02-10 | Roche Diagnostic Operations, Inc. | System and method for determining an abused sensor during analyte measurement |
US8206565B2 (en) | 2003-06-20 | 2012-06-26 | Roche Diagnostics Operation, Inc. | System and method for coding information on a biosensor test strip |
US6942769B2 (en) * | 2003-08-05 | 2005-09-13 | Bt Medical Corp. | Electrochemical sensor strip with low porosity screen |
WO2005032362A2 (en) * | 2003-09-30 | 2005-04-14 | Roche Diagnostics Gmbh | Sensor with increaseed biocompatibility |
EP1713926B1 (de) | 2004-02-06 | 2012-08-01 | Bayer HealthCare, LLC | Oxidierbare verbindungen als interne referenz in biosensoren und deren verwendung |
US7569126B2 (en) | 2004-06-18 | 2009-08-04 | Roche Diagnostics Operations, Inc. | System and method for quality assurance of a biosensor test strip |
ATE427213T1 (de) * | 2004-06-23 | 2009-04-15 | Tesa Ag | Medizinischer biosensor, mittels dem biologische flussigkeiten untersucht werden |
JP5020832B2 (ja) * | 2005-03-04 | 2012-09-05 | バイエル・ヘルスケア・エルエルシー | 電気化学的バイオセンサでの酵素活性の安定化 |
ES2717135T3 (es) | 2005-07-20 | 2019-06-19 | Ascensia Diabetes Care Holdings Ag | Método para señalar al usuario para que añada una muestra adicional a una tira de prueba, método para medir la temperatura de una muestra y métodos para determinar la concentración de un analito basados en amperometría controlada |
EP3483598A1 (de) | 2005-09-30 | 2019-05-15 | Ascensia Diabetes Care Holdings AG | Gesteuerte voltammetrie |
KR100890988B1 (ko) * | 2007-10-29 | 2009-03-31 | 주식회사 아이센스 | 일정 소량의 시료를 균일하게 도입할 수 있는 시료도입부를구비한 전기화학적 바이오센서 |
WO2009059189A2 (en) * | 2007-11-02 | 2009-05-07 | Paradigm Sensors Llc | Processing system and method for hand-held impedance spectroscopy analysis device for determining biofuel properties |
WO2009076302A1 (en) | 2007-12-10 | 2009-06-18 | Bayer Healthcare Llc | Control markers for auto-detection of control solution and methods of use |
US8025788B2 (en) * | 2009-04-24 | 2011-09-27 | Lifescan Scotland Limited | Method for manufacturing an enzymatic reagent ink |
US20100273249A1 (en) * | 2009-04-24 | 2010-10-28 | Lifescan Scotland Limited | Analytical test strips |
US9535027B2 (en) | 2012-07-25 | 2017-01-03 | Abbott Diabetes Care Inc. | Analyte sensors and methods of using same |
EP3388824B1 (de) | 2013-03-15 | 2021-04-14 | Roche Diabetes Care GmbH | Verfahren zur erkennung eines hohen gehalts an antioxidationsmitteln bei elektrochemischen messungen und zur ausfallsicherung einer analytkonzentration sowie vorrichtungen und systeme damit |
KR101727446B1 (ko) | 2013-03-15 | 2017-04-14 | 에프. 호프만-라 로슈 아게 | 바이오센서 알고리즘들을 구성하는데 사용된 데이터를 스케일링하는 방법들 뿐만 아니라 이를 통합한 기기들, 장치들 및 시스템들 |
EP2972273B1 (de) | 2013-03-15 | 2020-10-21 | Roche Diabetes Care GmbH | Verfahren zur verwendung von informationen aus erholungsimpulsen bei elektrochemischen analytmessungen sowie vorrichtungen damit |
CN105283757B (zh) | 2013-03-15 | 2019-04-23 | 豪夫迈·罗氏有限公司 | 对分析物的电化学测量进行防故障的方法以及结合该方法的设备、装置和系统 |
CA3035874A1 (en) | 2016-10-05 | 2018-04-12 | F. Hoffmann-La Roche Ag | Detection reagents and electrode arrangements for multi-analyte diagnostic test elements, as well as methods of using the same |
EP3589746B1 (de) * | 2017-03-03 | 2021-05-19 | Siemens Healthcare Diagnostics Inc. | Biosensoren mit nanokügelchen und verfahren zur herstellung und verwendung davon |
CN110146567A (zh) * | 2018-11-05 | 2019-08-20 | 浙江大学山东工业技术研究院 | 一种基于微球的抗干扰丝网印刷电极 |
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JP3372195B2 (ja) * | 1997-08-14 | 2003-01-27 | 日本特殊陶業株式会社 | NOxガス濃度検出器及び検出器に用いる電極の製造方法 |
US6129823A (en) | 1997-09-05 | 2000-10-10 | Abbott Laboratories | Low volume electrochemical sensor |
US5997817A (en) | 1997-12-05 | 1999-12-07 | Roche Diagnostics Corporation | Electrochemical biosensor test strip |
US6662439B1 (en) | 1999-10-04 | 2003-12-16 | Roche Diagnostics Corporation | Laser defined features for patterned laminates and electrodes |
US6615583B2 (en) | 2001-01-16 | 2003-09-09 | Falcom Co., Ltd | Pressurizing apparatus |
-
1999
- 1999-12-23 US US09/471,571 patent/US6627057B1/en not_active Expired - Fee Related
-
2000
- 2000-12-18 CA CA002328751A patent/CA2328751C/en not_active Expired - Fee Related
- 2000-12-19 EP EP00127769A patent/EP1113263A3/de not_active Withdrawn
- 2000-12-22 JP JP2000390466A patent/JP3947356B2/ja not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US6627057B1 (en) | 2003-09-30 |
CA2328751A1 (en) | 2001-06-23 |
EP1113263A2 (de) | 2001-07-04 |
JP2001208716A (ja) | 2001-08-03 |
EP1113263A3 (de) | 2004-01-07 |
CA2328751C (en) | 2008-06-17 |
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