JP3940398B2 - 多基質バイオチップユニット - Google Patents
多基質バイオチップユニット Download PDFInfo
- Publication number
- JP3940398B2 JP3940398B2 JP2003551588A JP2003551588A JP3940398B2 JP 3940398 B2 JP3940398 B2 JP 3940398B2 JP 2003551588 A JP2003551588 A JP 2003551588A JP 2003551588 A JP2003551588 A JP 2003551588A JP 3940398 B2 JP3940398 B2 JP 3940398B2
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- JP
- Japan
- Prior art keywords
- cavity
- housing
- substrate
- analyzer
- marker
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
- B01L3/5085—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L9/00—Supporting devices; Holding devices
- B01L9/56—Means for indicating position of a recipient or sample in an array
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/0054—Means for coding or tagging the apparatus or the reagents
- B01J2219/00545—Colours
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/0054—Means for coding or tagging the apparatus or the reagents
- B01J2219/00547—Bar codes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/0054—Means for coding or tagging the apparatus or the reagents
- B01J2219/00572—Chemical means
- B01J2219/00576—Chemical means fluorophore
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/0068—Means for controlling the apparatus of the process
- B01J2219/00702—Processes involving means for analysing and characterising the products
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0848—Specific forms of parts of containers
- B01L2300/0858—Side walls
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0887—Laminated structure
Description
Claims (15)
- 所定の位置に少なくとも1つの基準マーカと複数の基質とを含む多基質チップを、少なくとも部分的に封入するハウジングを含み、
前記少なくとも1つの基準マーカが、第1の角度で第1の光源によって照明され、前記複数の基質のうちの少なくとも1つが、第2の角度で第2の光源によって照明され、
前記ハウジングが、前記第1の角度と前記第2の角度が同一でないように構成される分析装置。 - 前記ハウジングの少なくとも一部分が透明である、請求項1に記載の分析装置。
- 前記基準マーカが、前記複数の基質のうちの少なくとも1つに対して所定の位置にある、請求項1に記載の分析装置。
- 前記基準マーカが暗視野で照明される、請求項1に記載の分析装置。
- 前記基準マーカの照明が、前記多基質チップを光学機器の焦点面に向けるように使用される、請求項1に記載の分析装置。
- さらに第2の基準マーカを含む、請求項1に記載の分析装置。
- 前記第1の角度と前記第2の角度との間の差異が少なくとも45度である、請求項1に記載の分析装置。
- バーコード、規格、および登録マーカのうちの少なくとも1つをさらに含む、請求項1に記載の分析装置。
- 前記基準マーカが化学発光マーカまたは蛍光マーカを含む、請求項1に記載の分析装置。
- 前記第1の光源が、第1の波長で発光する発光ダイオードを含み、前記第2の光源が、第2の波長で発光するレーザを含み、前記第1と第2の波長が少なくとも20nm離れている、請求項1に記載の分析装置。
- 前記多基質チップが、ハウジングによって少なくとも部分的に形成される空洞内に配置され、前記空洞が、0.01mlから10mlの間の所定の容積を有する、請求項1に記載の分析装置。
- 前記空洞が、所定の量よりも大きい量の液体を含むときに、前記空洞がオーバフロー区画と流体連通する、請求項11に記載の分析装置。
- 前記ハウジングが、熱エネルギーおよび超音波エネルギーのうちの少なくとも一方を、前記空洞内に配置された前記多基質チップおよび流体のうちの少なくとも一方へと伝達するように構成されるベース要素を含む、請求項12に記載の分析装置。
- 前記複数の基質のうちの少なくとも1つが、サンプル流体からの分析対象に結合し、前記分析対象の結合が、前記多基質チップが実質的に水平方向の位置にあるときに検出される、請求項1に記載の分析装置。
- 請求項1に記載の分析装置を複数含み、前記複数の分析装置は、第1の装置のベース要素が第2の装置のハウジング上に配置されるように積層されるマガジン。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
USPCT/US01/47991 | 2001-12-11 | ||
PCT/US2001/047991 WO2002057416A2 (en) | 2000-12-12 | 2001-12-11 | Improved biochip |
PCT/US2002/003917 WO2003050591A1 (en) | 2001-12-11 | 2002-01-24 | Multi-substrate biochip unit |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2007042089A Division JP4588730B2 (ja) | 2001-12-11 | 2007-02-22 | 多基質バイオチップユニット |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2005512097A JP2005512097A (ja) | 2005-04-28 |
JP3940398B2 true JP3940398B2 (ja) | 2007-07-04 |
Family
ID=21743111
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2003551588A Expired - Fee Related JP3940398B2 (ja) | 2001-12-11 | 2002-01-24 | 多基質バイオチップユニット |
JP2007042089A Expired - Fee Related JP4588730B2 (ja) | 2001-12-11 | 2007-02-22 | 多基質バイオチップユニット |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2007042089A Expired - Fee Related JP4588730B2 (ja) | 2001-12-11 | 2007-02-22 | 多基質バイオチップユニット |
Country Status (7)
Country | Link |
---|---|
US (2) | US20050221283A1 (ja) |
EP (1) | EP1454177B1 (ja) |
JP (2) | JP3940398B2 (ja) |
AT (1) | ATE359534T1 (ja) |
AU (1) | AU2002248414A1 (ja) |
DE (1) | DE60219517T2 (ja) |
WO (1) | WO2003050591A1 (ja) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
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US7273591B2 (en) * | 2003-08-12 | 2007-09-25 | Idexx Laboratories, Inc. | Slide cartridge and reagent test slides for use with a chemical analyzer, and chemical analyzer for same |
US7588733B2 (en) | 2003-12-04 | 2009-09-15 | Idexx Laboratories, Inc. | Retaining clip for reagent test slides |
EP1935992A3 (en) | 2003-12-23 | 2008-12-03 | Autogenomics, Inc. | Multiplexed nucleic acid analysis with high specificity for human papilloma virus |
ATE487799T1 (de) | 2003-12-23 | 2010-11-15 | Autogenomics Inc | Multiplexanalyse von nukleinsäuren zur bestimmung von genotypen des humanen papillomavirus |
JP4711125B2 (ja) * | 2005-09-27 | 2011-06-29 | 横河電機株式会社 | バイオチップ、バイオチップ読み取り装置、およびバイオチップ読み取り方法 |
JP4955244B2 (ja) * | 2005-09-27 | 2012-06-20 | 横河電機株式会社 | バイオチップ読み取り装置およびバイオチップ読み取り方法 |
WO2009016548A2 (en) | 2007-07-27 | 2009-02-05 | Koninklijke Philips Electronics N.V. | Method and system for imaging samples |
KR101510351B1 (ko) | 2009-02-17 | 2015-04-06 | 삼성전자주식회사 | 마이크로어레이 및 마이크로어레이 신호를 분석하는 방법 |
US10551376B2 (en) | 2013-02-01 | 2020-02-04 | The General Hospital Corporation | Capture and release of particles from liquid samples |
EP3368220B1 (en) | 2015-10-26 | 2020-07-22 | IDEXX Laboratories, Inc. | Hematology test slide |
JPWO2022163124A1 (ja) * | 2021-01-29 | 2022-08-04 |
Family Cites Families (39)
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US4357363A (en) * | 1978-12-27 | 1982-11-02 | Eastman Kodak Company | Element, structure and method for the analysis or transport of liquids |
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-
2001
- 2001-12-11 US US10/433,766 patent/US20050221283A1/en not_active Abandoned
-
2002
- 2002-01-24 DE DE60219517T patent/DE60219517T2/de not_active Expired - Lifetime
- 2002-01-24 AU AU2002248414A patent/AU2002248414A1/en not_active Abandoned
- 2002-01-24 AT AT02717407T patent/ATE359534T1/de not_active IP Right Cessation
- 2002-01-24 EP EP02717407A patent/EP1454177B1/en not_active Expired - Lifetime
- 2002-01-24 WO PCT/US2002/003917 patent/WO2003050591A1/en active IP Right Grant
- 2002-01-24 JP JP2003551588A patent/JP3940398B2/ja not_active Expired - Fee Related
-
2007
- 2007-02-22 JP JP2007042089A patent/JP4588730B2/ja not_active Expired - Fee Related
-
2010
- 2010-08-27 US US12/870,337 patent/US20110086771A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
ATE359534T1 (de) | 2007-05-15 |
JP4588730B2 (ja) | 2010-12-01 |
EP1454177A4 (en) | 2006-03-22 |
US20110086771A1 (en) | 2011-04-14 |
US20050221283A1 (en) | 2005-10-06 |
AU2002248414A1 (en) | 2003-06-23 |
EP1454177A1 (en) | 2004-09-08 |
JP2007163514A (ja) | 2007-06-28 |
EP1454177B1 (en) | 2007-04-11 |
DE60219517D1 (de) | 2007-05-24 |
JP2005512097A (ja) | 2005-04-28 |
DE60219517T2 (de) | 2008-01-03 |
WO2003050591A1 (en) | 2003-06-19 |
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