JP3939744B2 - 置換３−アルキルおよび３−アルケニルアゼチジン誘導体 - Google Patents

置換３−アルキルおよび３−アルケニルアゼチジン誘導体 Download PDF

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JP3939744B2
JP3939744B2 JP2006533655A JP2006533655A JP3939744B2 JP 3939744 B2 JP3939744 B2 JP 3939744B2 JP 2006533655 A JP2006533655 A JP 2006533655A JP 2006533655 A JP2006533655 A JP 2006533655A JP 3939744 B2 JP3939744 B2 JP 3939744B2
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methyl
mmol
chlorophenyl
difluorophenyl
solution
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JP2007500246A (ja
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ベーカー，ロバート・ケイ
パオ，チヤンミン
ミヤオ，シユーウー
ルプレヒト，キヤサリーン・エム
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Merck and Co Inc
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Merck and Co Inc
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    • C07—ORGANIC CHEMISTRY
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    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/04—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/10—Laxatives
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    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
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    • A61P25/00—Drugs for disorders of the nervous system
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    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
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    • A61P25/00—Drugs for disorders of the nervous system
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    • A61P25/00—Drugs for disorders of the nervous system
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    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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    • A61P9/00—Drugs for disorders of the cardiovascular system
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    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

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  • Chemical & Material Sciences (AREA)
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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Cardiology (AREA)
  • Pulmonology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Psychology (AREA)
  • Urology & Nephrology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Anesthesiology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Vascular Medicine (AREA)
  • Addiction (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2006533655A 2003-06-11 2004-06-09 置換３−アルキルおよび３−アルケニルアゼチジン誘導体 Expired - Fee Related JP3939744B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US47785003P 2003-06-11 2003-06-11
PCT/US2004/018348 WO2005000809A1 (en) 2003-06-11 2004-06-09 Substituted 3-alkyl and 3-alkenyl azetidine derivatives

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JP2007031781A Division JP2007186518A (ja) 2003-06-11 2007-02-13 置換３−アルキルおよび３−アルケニルアゼチジン誘導体

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JP2007500246A JP2007500246A (ja) 2007-01-11
JP3939744B2 true JP3939744B2 (ja) 2007-07-04

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JP2006533655A Expired - Fee Related JP3939744B2 (ja) 2003-06-11 2004-06-09 置換３−アルキルおよび３−アルケニルアゼチジン誘導体
JP2007031781A Pending JP2007186518A (ja) 2003-06-11 2007-02-13 置換３−アルキルおよび３−アルケニルアゼチジン誘導体
JP2011053759A Withdrawn JP2011144196A (ja) 2003-06-11 2011-03-11 置換３−アルキルおよび３−アルケニルアゼチジン誘導体

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JP2007031781A Pending JP2007186518A (ja) 2003-06-11 2007-02-13 置換３−アルキルおよび３−アルケニルアゼチジン誘導体
JP2011053759A Withdrawn JP2011144196A (ja) 2003-06-11 2011-03-11 置換３−アルキルおよび３−アルケニルアゼチジン誘導体

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US (2) US7485732B2 (cg-RX-API-DMAC7.html)
EP (1) EP1636181A1 (cg-RX-API-DMAC7.html)
JP (3) JP3939744B2 (cg-RX-API-DMAC7.html)
KR (1) KR20060019587A (cg-RX-API-DMAC7.html)
CN (1) CN1802351A (cg-RX-API-DMAC7.html)
AU (1) AU2004252109B2 (cg-RX-API-DMAC7.html)
BR (1) BRPI0411131A (cg-RX-API-DMAC7.html)
CA (1) CA2527933C (cg-RX-API-DMAC7.html)
CO (1) CO5650244A2 (cg-RX-API-DMAC7.html)
EC (1) ECSP056207A (cg-RX-API-DMAC7.html)
IL (1) IL172417A0 (cg-RX-API-DMAC7.html)
IS (1) IS8146A (cg-RX-API-DMAC7.html)
MA (1) MA27847A1 (cg-RX-API-DMAC7.html)
MX (1) MXPA05013583A (cg-RX-API-DMAC7.html)
NO (1) NO20060141L (cg-RX-API-DMAC7.html)
NZ (1) NZ543451A (cg-RX-API-DMAC7.html)
RU (1) RU2006100298A (cg-RX-API-DMAC7.html)
UA (1) UA83230C2 (cg-RX-API-DMAC7.html)
WO (1) WO2005000809A1 (cg-RX-API-DMAC7.html)
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007186518A (ja) * 2003-06-11 2007-07-26 Merck & Co Inc 置換３−アルキルおよび３−アルケニルアゼチジン誘導体

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AR058199A1 (es) * 2005-11-28 2008-01-23 Merck & Co Inc Derivados de 3- alquilazetidina sustituidos con heterociclos
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KR101273566B1 (ko) 2011-09-05 2013-06-11 한국과학기술연구원 신규한 아제티딘 유도체 및 이를 함유하는 항우울제 조성물
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US7906503B2 (en) 2011-03-15
CA2527933C (en) 2009-08-11
UA83230C2 (ru) 2008-06-25
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US20090069284A1 (en) 2009-03-12
CO5650244A2 (es) 2006-06-30
US20060293299A1 (en) 2006-12-28
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