JP3571727B2 - 経皮的センサ挿入セット - Google Patents
経皮的センサ挿入セット Download PDFInfo
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- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
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- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
- A61M5/172—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body electrical or electronic
- A61M5/1723—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body electrical or electronic using feedback of body parameters, e.g. blood-sugar, pressure
- A61M2005/1726—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body electrical or electronic using feedback of body parameters, e.g. blood-sugar, pressure the body parameters being measured at, or proximate to, the infusion site
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- A61M2230/00—Measuring parameters of the user
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- A61M2230/201—Glucose concentration
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
- A61M25/06—Body-piercing guide needles or the like
- A61M25/0606—"Over-the-needle" catheter assemblies, e.g. I.V. catheters
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Description
本発明は、広くは、患者の身体内の選択された部位にセンサを配置する装置及び方法に関し、より詳しくは、例えば血中グルコースの周期的読取りを行なうのに使用される形式の可撓性薄膜センサの経皮的配置を迅速且つ容易に行なうための改良された比較的簡単な挿入セットに関する。
最近では、患者の血液中の特異的原因物質(specific agents)の検出及び/又は定量化を行なう医療用途を含む一定範囲の用途のための種々の電気化学センサが開発されている。一例として、グルコースセンサは、糖尿病患者の血中グルコースレベルの指標を得るべく使用するため開発されている。このような読取りは、治療養生(一般に、患者へのインシュリンの規則的投与を含む)のモニタリング及び/又は調節に特に有効である。この点に関し、血中グルコースの読取りは、米国特許第4,562,751号、第4,678,408号及び第4,685,903号に概略的に説明されている体外形の半自動薬剤注入ポンプ、又は米国特許第4,573,994号に概略的に説明されている移植可能な自動薬剤注入ポンプに関して特に有効である。
患者の血液又は他の細胞外液と直接接触するセンサ電極の経皮的配置を行なうための比較的小形で可撓性のある電気化学的センサが開発されており、このようなセンサは、長時間に亘る周期的読取りを行なうのに使用できる。1つの形態では、可撓性のある経皮的センサは薄膜マスク技術に従って構成され、この技術による細長いセンサは、ポリイミドシート又は同様な材料からなる可撓性絶縁層の間に封入された薄膜導電要素を有する。一般に、このような薄膜センサの先端側端部には、患者の血液等と直接接触して経皮的配置される露出電極が設けられ、体外に配置される手元側端部には、適当なモニタ装置との電気的接続が便利に行なえる露出導電接点が設けられている。このような薄膜センサは患者のモニタリング用として非常に有望であるが、残念なことに、センサ電極が患者の血液又は他の細胞外液と直接接触するように経皮的に配置することは困難である。一般譲渡された係属中の1994年3月14日付米国特許出願第08/213,101号、1994年3月15日付米国特許出願第08/212,961号、及び1994年5月9日付米国特許出願第08/239,960号(これらの出願は、本願に援用する)には、改良された薄膜センサ及び関連挿入セットが記載されている。
本発明は、より詳しくは、センサ電極が患者の血液又は他の細胞外液と直接接触するようにして、薄膜センサを迅速且つ容易に患者に配置できる改良されたセンサ挿入セットに関する。
発明の要約
本発明によれば、薄膜電気化学センサのような可撓性センサを、患者の体内の選択された部位に配置するための経皮的挿入セットが提供される。挿入セットは、患者の皮膚に取り付ける(seated mounting)ようになった取付けベースを通って延びるスロット付き挿入針を有する。可撓性のある薄膜センサは、取付けベースにより支持される手元側セグメントと、取付けベースから突出し且つ1つ以上のセンサ電極が設けられた先端側セグメントとを有する。センサの先端側セグメントは、保護カテーテル(該カテーテルは取付けベースから延び且つその一部は挿入針内に摺動可能に受け入れられる)内に支持される。カテーテルに形成された1つ以上の窓は、センサの先端側セグメントのセンサ電極とほぼ整合するように位置決めされる。
取付けベースが患者の皮膚に押し付けられると、挿入針が皮膚を突き刺して、センサの先端側セグメントが収容されたカテーテルが経皮的に配置される。挿入針は、カテーテル及びセンサの先端側セグメントを患者の体内に残して、取付けベースから引き抜くことができる。これにより、先端側セグメントのセンサ電極が窓(単一又は複数)を介して露出され、皮下部位、管内部位、筋肉部位又は静脈内部位等の患者の選択された部位で、患者の体液と直接接触する。センサの手元側端部の導電性接点は適当なモニタ装置に電気的に接続でき、これにより適当な血中化学物質(blood chemistry)の読取りを行なうことができる。
好ましい形態では、挿入針は、180゜より幾分大きい円弧断面形状を有する。針のこの円弧断面構造部分は挿入セットの取付けベースから下方に突出し、且つ患者の皮膚を突き刺す鋭い先端部に終端している。保護カニューレの第1部分は挿入針内に嵌装される断面形状を有し、且つ取付けベースから、針の先端部の少なくとも僅か手前に終端する先端部まで延びている。カニューレのこの第1部分は、挿入針の円弧状輪郭部分内で長手方向に摺動できるけれども、挿入針からカニューレが横方向に外れてしまうことを防止するサイズを有する。カニューレの第2部分は、前記第1部分と平行に長手方向に延び、且つ薄膜センサの先端側端部を受け入れて案内支持する管孔を形成する。この管孔の先端側端部又はこの近傍に少なくとも1つの窓が形成されており、該窓は、センサ電極を患者の体液に露出させるため、センサ電極とほぼ整合するように位置決めされている。好ましい形態では、カニューレは、弾性のある医用プラスチック又はエラストマから構成され、カニューレの第2部分は挿入針と協働して、患者の皮膚への容易な挿入が行なえる実質的に円形の断面形状を形成する。
挿入中に、挿入針及び保護カニューレが協働して、センサを保護し且つ所望の経皮的配置位置に案内する。次に、挿入針を引き抜くことができ、このとき、スロット付き針の幾何学的形状により、挿入針がカニューレ上を摺動し且つカニューレの第2部分から長手方向に分離することが可能になり、これにより、カニューレ及びセンサは、選択された挿入部位に残される。
本発明の他の特徴及び長所は、本発明の原理を例示する添付図面に関連して述べる以下の詳細な説明から一層明瞭になるであろう。
【図面の簡単な説明】
添付図面は本発明を例示するものであり、
第1図は、本発明の新規な特徴を具現する経皮的センサ挿入セットを示す斜視図、
第2図は、第1図の2−2線に沿う拡大縦断面図、
第3図は、第1図及び第2図の挿入セットに使用されるスロット付き挿入針の拡大縦断面図、
第4図は、第3図の4−4線に沿う拡大断面図、
第5図は、第3図の5−5線に沿う拡大断面図、
第6図は、第2図中の円で囲んだ領域の拡大部分断面図、及び、
第7図は、第2図の7−7線に沿う拡大断面図である。
好ましい実施例の詳細な説明
例示図面に示すように、第1図において参照番号10で全体を示す改良されたセンサ挿入セットは、可撓性センサ12(第2図)を、患者の身体内の選択された部位に経皮的に配置するためのものである。挿入セット10は、カニューレ15の迅速且つ容易な経皮的配置を行なうための剛性のある中空スロット付き挿入針14を有する。挿入針14内にはセンサ12の先端側セグメント16が配置され、該先端側セグメント16は、カニューレ15の窓19を通って患者の液体に露出される1つ以上のセンサ電極18を有している。次に、挿入針14は、カニューレ15を、センサの先端側セグメント16及びセンサ電極18と共に選択された挿入部位に残したまま引き出される。
本発明の経皮的センサ挿入セット10は、患者の状態を表す特異的血液パラメータをモニタリングするのに使用される形式の可撓性薄膜電気化学センサの正確な配置が容易に行なえるように特別設計されている。挿入セット10は、センサ12を、患者の不快感及び外傷を最小にする方法で、皮下に、又は患者の身体内の他の選択された部位に配置できるように設計されている。1つの好ましい用途では、センサ12は、糖尿病患者にインシュリンを投与するため、米国特許第4,562,751号、第4,678,408号、第4,685,903号又は第4,573,994号に開示されているような体外形又は移植形の自動又は半自動薬剤注入ポンプと組み合わせて使用することもできる。
好ましい形態では、可撓性電気化学センサ12はいわゆる薄膜マスク技術により作られ、ポリイミド膜又はポリイミドシートのような選択された絶縁材料の層の間に埋設又は封入された細長い薄膜導体を有する。センサ12の先端側セグメント16の先端部に設けられたセンサ電極18(図面には誇張して示されている)は、センサが経皮的に配置されたときに患者の血液と直接接触できるように、1つの絶縁層を通って露出されている。先端側セグメント16は手元側セグメント20(第2図)に接続されており、該手元側セグメント20の端部は、適当な導電性接触パッド等(これも、1つの絶縁層を通って露出されている)に終端している。当該技術分野で知られており且つ第2図に概略的に示すように、手元側セグメント20及び該セグメントの接触パッドは、センサ電極18から与えられる信号に応答して患者の状態をモニタリングするための適当なモニタ22に電気的に接続できるようになっている。「薄膜センサの製造方法(METHOD OF FABRICATING THIN FILM SENSORS)」という名称に係る1994年3月15日付米国特許出願第08/212,961号(該出願は、本願に援用する)には、この一般的形式の可撓性薄膜センサについての他の説明がなされている。手元側セグメント20は、「可撓回路コネクタ(FLEX CIRCUIT CONNECTOR)」という名称に係る係属中の1994年5月9日付米国特許出願第08/239,960号(該出願も本願に援用する)に示され且つ説明されているようなコネクタブロック24を介してモニタ22に電気的に接続するのが便利である。
センサ12は、患者の皮膚上に置くことができる取付けベース26により支持される。図示のように、取付けベース26は大形でほぼ矩形のパッドを有し、該パッドの下面には適当な感圧接着剤の層がコーティングされている。この接着剤の層には、通常、挿入セット10の使用準備が整うまで接着剤の層を覆い且つ保護するための剥離紙ストリップ28が設けられる。第1図及び第2図に示すように、取付けベース26は上層30及び下層32を有し、これらの両層の間に可撓性センサ12の手元側セグメント20がサンドイッチされている。手元側センサセグメント20は先端側セグメント16に接続される最先端部を有し、該最先端部は、ベース下層32に形成されたスロット34を通って下方に延びるように傾斜して曲げられている。
挿入針14は、ベース上層30に形成された針ポート36と、ベース下層32の下スロット34とを通って滑り嵌装されるようになっている。図示のように、挿入針14は、鋭い先端部38及び開放スロット40を有し、該スロット40は、針の下面の先端部38から、少なくともベース下層32のスロット34内の位置まで延びている。取付けベース26の上方では、挿入針14を完全円形の断面形状にすることができ、挿入針14の後端部は閉鎖するのが好ましい。好ましい形態では、スロット付き挿入針14は、180゜より大きい円弧状寸法(例えば、約210゜の円弧状寸法)すなわちスパンをもつ円弧状断面を有する。これにより、針には、約150゜の円弧状寸法をもつ長手方向スロットが形成される。
第6図及び第7図にはカニューレ15が最も良く示されており、カニューレ15は、挿入針14内に嵌装されて取付けベース26から下方に延びる、円弧状断面をもつ第1部分44を有する。このカニューレ15は適当な医用プラスチック又はポリテトラフルオロエチレン、シリコーン等のエラストマで構成され、且つセンサ12の先端側セグメント16を受け入れ、保護し且つ案内可能に支持するための開放管孔42が第2部分に形成されている。カニューレ15の一端は取付けベース26の下層32に形成されたスロット34内に嵌装され、この場合、カニューレ15は適当な接着剤又は他の選択された取付け手段により取付けベース26に固定するのが好ましい。カニューレ15は、取付けベース26から下方に傾斜して延び、挿入針14内に嵌装される第1部分44は、針の先端部38から僅かに手前に終端させる。重要なことは、センサ12を経皮的に配置したときにセンサ電極18が患者の体液に露出されるように、管孔42の先端側端部の近くで且つセンサとほぼ整合する箇所に少なくとも1つの窓19を形成することである。
好ましい形態では、患者の皮膚を通して容易に挿入できるようにするため、カニューレ15の第2部分42は、第7図に示すように、挿入針14の円弧状形状と協働して実質的に完全円形の幾何学的形状を形成する円弧状の断面形状を有する。カニューレ15の第1部分44は、針14内に滑り嵌装されるように、第2部分42より小さい断面輪郭を有する。これにより、針14及び第1カニューレ部分44は機械的に噛み合って、カニューレ15が挿入針14から横方向に外れてしまうことを防止すると同時に、カニューレの第1部分44上での針14の長手方向摺動は許容する。カニューレの第2部分42の先端部すなわち自由端部は、挿入針14の傾斜切断先端部38との連続形状を形成するように、第2図に示すように、適当に切断するか、或る傾斜角度に形成する。
使用に際し、挿入セット10は、患者の体内の選択された部位に、センサの先端側セグメント16を迅速且つ容易に経皮的配置することができる。より詳しくは、取付けベース26から剥離紙ストリップ28(第1図)を除去すれば、取付けベース26を患者の皮膚上に押し付けて取り付けることができる。この段階において、挿入針14は患者の皮膚を突き刺し、且つセンサの先端側セグメント16が納められた保護カニューレ15を、適当な経皮的配置部位まで運ぶ。挿入の間、カニューレ15は、可撓性センサを所望の挿入部位まで運ぶための安定した支持及びガイド構造を形成する。
取付けベース26が患者の皮膚に取り付けられ、センサ12が経皮的に配置されたならば、挿入針14を患者から引き抜くことができる。この引抜き段階の間、挿入針14が保護カニューレ15の第1部分44上を摺動し、電極18が設けられたセンサの先端側セグメント16が、選択された挿入部位に残される。これらの電極18は、窓19を介して患者の体液に直接露出される。センサの手元側セグメント20はモニタ22に適当に接続され、これにより、糖尿病患者の血中グルコースの読取り等の血中化学物質の読取りを行なうため、長時間に亘ってセンサを使用できる。所望ならば、カニューレ15の第1部分44を図示のような中空状に形成し、これを、電極18の近傍への薬剤及び/又はセンサキャリブレーション液の供給、又は血液等の患者の体液の分析のための抽出に利用することもできる。
従って、本発明の経皮的センサ挿入セットは、可撓性のある薄膜電気化学センサを、患者の体内の選択された位置に迅速且つ容易に配置できる比較的簡単な装置を構成する。
当業者ならば、本発明の経皮的センサ挿入セットについての種々の変更及び改良は明白であろう。従って、本発明は、請求の範囲の記載を除き、上記説明及び添付図面の例示によっていかなる制限をも受けることはない。
Claims (16)
- 患者の皮膚に取り付けることができる取付けベースと、
該取付けベースにより支持される手元側セグメントと、前記取付けベースから突出しており且つ少なくとも1つの電極を備えた先端側セグメントとを有する可撓性センサと、
前記取付けベースから突出しており且つセンサの先端側セグメントを内部に収容するカニューレとを有し、該カニューレには、前記センサの先端側セグメントの少なくとも1つのセンサ電極とほぼ整合するように配置された少なくとも1つの窓が形成され、
前記取付けベースから突出するように該取付けベースにより支持され且つ前記カニューレの少なくとも一部を内部に嵌装する中空挿入針を更に有し、該挿入針には、この一側面に沿って長手方向に延びたスロットが形成され、前記針を、前記取付けベース及び前記カニューレの嵌装部分から引き抜くことができることを特徴とする経皮的センサ挿入セット。 - 前記センサは可撓性薄膜センサであることを特徴とする請求の範囲第1項に記載の経皮的センサ挿入セット。
- 前記センサは電気化学センサであることを特徴とする請求の範囲第1項に記載の経皮的センサ挿入セット。
- 前記センサはグルコースセンサであることを特徴とする請求の範囲第1項に記載の経皮的センサ挿入セット。
- 前記挿入針は前記取付けベースを通って延びており、前記挿入針は、前記カニューレの前記嵌装部分から分離させるため、前記取付けベースから手で引き抜くことができることを特徴とする請求の範囲第1項に記載の経皮的センサ挿入セット。
- 前記挿入針の前記スロットは、挿入針の下面に開口していることを特徴とする請求の範囲第1項に記載の経皮的センサ挿入セット。
- 前記カニューレは、前記挿入針内に嵌装される第1部分と、前記センサの先端側セグメントを内部に支持する管孔を形成する第2部分とを有し、該第2部分には前記少なくとも1つの窓が形成されていることを特徴とする請求の範囲第1項に記載の経皮的センサ挿入セット。
- 前記センサの手元側セグメントをモニタに接続する手段を有することを特徴とする請求の範囲第1項に記載の経皮的センサ挿入セット。
- 前記取付けベースは、該ベースを患者の皮膚に着脱可能に取り付ける手段を有することを特徴とする請求の範囲第1項に記載の経皮的センサ挿入セット。
- 前記挿入針は、180゜より大きい円弧寸法をもつ円弧断面形状を有し、前記カニューレの第1部分は、前記針とカニューレの第1部分とが相対的に長手方向に摺動できるけれども、前記カニューレが前記針から横方向に外れることは防止するサイズ及び形状を有し、これにより、前記挿入針は、取付けベースを患者の皮膚上に置いたときに患者の皮膚を突き刺し、前記針は、センサの先端側セグメントを収容した前記カニューレを、選択された挿入部位に運び、前記針は、前記センサの先端側セグメントを収容した前記カニューレを選択された挿入部位に残すため、前記カニューレ及び取付けベースから摺動可能に引き抜くことができることを特徴とする請求の範囲第7項に記載の経皮的センサ挿入セット。
- 前記カニューレの第1部分が前記針内に嵌装されると、針及びカニューレの第2部分は、協働して、実質的に円弧状の断面形状を形成することを特徴とする請求の範囲第10項に記載の経皮的センサ挿入セット。
- 患者の皮膚に取り付けることができる取付けベースと、
該取付けベースから突出しているカニューレと、
前記取付けベースから突出するように該取付けベースにより支持され且つ前記カニューレの少なくとも一部が内部に嵌装された中空挿入針とを有し、該挿入針には、この一側面に沿って長手方向に延びるスロットであって、挿入針を、前記取付けベース及びカニューレの嵌装部分から摺動引抜き可能にするスロットが形成されており、
前記挿入針は、前記カニューレの嵌装部分が前記針から横方向に外れることを防止すると同時に、前記針とカニューレとが互いに長手方向に摺動することは許容するため、180゜より大きい円弧状寸法をもつ断面形状を有することを特徴とする経皮的挿入セット。 - 前記挿入針は前記取付けベースを通って延びており、前記挿入針は、前記カニューレの前記嵌装部分から分離させるため、前記取付けベースから手で引き抜くことができることを特徴とする請求の範囲第12項に記載の経皮的挿入セット。
- 前記挿入針の前記スロットは、挿入針の下面に開口していることを特徴とする請求の範囲第12項に記載の経皮的挿入セット。
- 前記カニューレは、前記挿入針内に嵌装される第1部分と、管孔を形成する第2部分とを備えていることを特徴とする請求の範囲第12項に記載の経皮的挿入セット。
- 前記カニューレの第1部分が前記針内に嵌装されると、針及びカニューレの第2部分は、協働して、実質的に円弧状の断面形状を形成することを特徴とする請求の範囲第12項に記載の経皮的挿入セット。
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Application Number | Priority Date | Filing Date | Title |
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US08/393,148 US5586553A (en) | 1995-02-16 | 1995-02-16 | Transcutaneous sensor insertion set |
US08/393,148 | 1995-02-16 | ||
PCT/US1996/001672 WO1996025088A1 (en) | 1995-02-16 | 1996-02-08 | Transcutaneous sensor insertion set |
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Publication Number | Publication Date |
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JPH09512199A JPH09512199A (ja) | 1997-12-09 |
JP3571727B2 true JP3571727B2 (ja) | 2004-09-29 |
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JP52500996A Expired - Fee Related JP3571727B2 (ja) | 1995-02-16 | 1996-02-08 | 経皮的センサ挿入セット |
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US (1) | US5586553A (ja) |
EP (1) | EP0748183B1 (ja) |
JP (1) | JP3571727B2 (ja) |
CA (1) | CA2186886C (ja) |
DE (1) | DE69630079T2 (ja) |
WO (1) | WO1996025088A1 (ja) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2009509646A (ja) * | 2005-09-30 | 2009-03-12 | インテュイティ メディカル インコーポレイテッド | 流体サンプル搬送装置および方法 |
JP2016119948A (ja) * | 2014-12-24 | 2016-07-07 | アークレイ株式会社 | センサ挿入方法、分析方法およびセンサ挿入システム |
Families Citing this family (574)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5593852A (en) | 1993-12-02 | 1997-01-14 | Heller; Adam | Subcutaneous glucose electrode |
CA2050057A1 (en) | 1991-03-04 | 1992-09-05 | Adam Heller | Interferant eliminating biosensors |
US5956501A (en) * | 1997-01-10 | 1999-09-21 | Health Hero Network, Inc. | Disease simulation system and method |
IE72524B1 (en) * | 1994-11-04 | 1997-04-23 | Elan Med Tech | Analyte-controlled liquid delivery device and analyte monitor |
US6093172A (en) * | 1997-02-05 | 2000-07-25 | Minimed Inc. | Injector for a subcutaneous insertion set |
US20070142776A9 (en) * | 1997-02-05 | 2007-06-21 | Medtronic Minimed, Inc. | Insertion device for an insertion set and method of using the same |
US7329239B2 (en) * | 1997-02-05 | 2008-02-12 | Medtronic Minimed, Inc. | Insertion device for an insertion set and method of using the same |
US6607509B2 (en) | 1997-12-31 | 2003-08-19 | Medtronic Minimed, Inc. | Insertion device for an insertion set and method of using the same |
ATE227844T1 (de) | 1997-02-06 | 2002-11-15 | Therasense Inc | Kleinvolumiger sensor zur in-vitro bestimmung |
US8527026B2 (en) | 1997-03-04 | 2013-09-03 | Dexcom, Inc. | Device and method for determining analyte levels |
US20050033132A1 (en) | 1997-03-04 | 2005-02-10 | Shults Mark C. | Analyte measuring device |
US6862465B2 (en) | 1997-03-04 | 2005-03-01 | Dexcom, Inc. | Device and method for determining analyte levels |
US7192450B2 (en) | 2003-05-21 | 2007-03-20 | Dexcom, Inc. | Porous membranes for use with implantable devices |
US9155496B2 (en) | 1997-03-04 | 2015-10-13 | Dexcom, Inc. | Low oxygen in vivo analyte sensor |
US7899511B2 (en) | 2004-07-13 | 2011-03-01 | Dexcom, Inc. | Low oxygen in vivo analyte sensor |
US6001067A (en) | 1997-03-04 | 1999-12-14 | Shults; Mark C. | Device and method for determining analyte levels |
DE19714572C1 (de) | 1997-04-09 | 1998-06-25 | Haindl Hans | Katheter zur Messung chemischer Parameter, insbesondere zum Einführen in biologisches Gewebe, Flüssigkeiten oder dergleichen |
US5779665A (en) * | 1997-05-08 | 1998-07-14 | Minimed Inc. | Transdermal introducer assembly |
US5954643A (en) * | 1997-06-09 | 1999-09-21 | Minimid Inc. | Insertion set for a transcutaneous sensor |
US7267665B2 (en) * | 1999-06-03 | 2007-09-11 | Medtronic Minimed, Inc. | Closed loop system for controlling insulin infusion |
US6558351B1 (en) | 1999-06-03 | 2003-05-06 | Medtronic Minimed, Inc. | Closed loop system for controlling insulin infusion |
CA2294610A1 (en) | 1997-06-16 | 1998-12-23 | George Moshe Katz | Methods of calibrating and testing a sensor for in vivo measurement of an analyte and devices for use in such methods |
DE19725680C2 (de) | 1997-06-18 | 2000-04-06 | Hans Haindl | Trichterförmige Kanülenanordnung zur Kathetereinführung |
DK1743667T3 (da) | 1997-12-31 | 2012-06-18 | Medtronic Minimed Inc | Indføringsindretning til et indføringssæt |
WO1999033504A1 (en) * | 1997-12-31 | 1999-07-08 | Minimed Inc. | Insertion device for an insertion set and method of using the same |
US6134461A (en) | 1998-03-04 | 2000-10-17 | E. Heller & Company | Electrochemical analyte |
US6103033A (en) | 1998-03-04 | 2000-08-15 | Therasense, Inc. | Process for producing an electrochemical biosensor |
US8688188B2 (en) | 1998-04-30 | 2014-04-01 | Abbott Diabetes Care Inc. | Analyte monitoring device and methods of use |
US8480580B2 (en) | 1998-04-30 | 2013-07-09 | Abbott Diabetes Care Inc. | Analyte monitoring device and methods of use |
US8346337B2 (en) | 1998-04-30 | 2013-01-01 | Abbott Diabetes Care Inc. | Analyte monitoring device and methods of use |
US8974386B2 (en) | 1998-04-30 | 2015-03-10 | Abbott Diabetes Care Inc. | Analyte monitoring device and methods of use |
US8465425B2 (en) | 1998-04-30 | 2013-06-18 | Abbott Diabetes Care Inc. | Analyte monitoring device and methods of use |
US6949816B2 (en) | 2003-04-21 | 2005-09-27 | Motorola, Inc. | Semiconductor component having first surface area for electrically coupling to a semiconductor chip and second surface area for electrically coupling to a substrate, and method of manufacturing same |
US6175752B1 (en) | 1998-04-30 | 2001-01-16 | Therasense, Inc. | Analyte monitoring device and methods of use |
US9066695B2 (en) | 1998-04-30 | 2015-06-30 | Abbott Diabetes Care Inc. | Analyte monitoring device and methods of use |
US5993423A (en) * | 1998-08-18 | 1999-11-30 | Choi; Soo Bong | Portable automatic syringe device and injection needle unit thereof |
US6558320B1 (en) | 2000-01-20 | 2003-05-06 | Medtronic Minimed, Inc. | Handheld personal data assistant (PDA) with a medical device and method of using the same |
US6251260B1 (en) | 1998-08-24 | 2001-06-26 | Therasense, Inc. | Potentiometric sensors for analytic determination |
US6254586B1 (en) * | 1998-09-25 | 2001-07-03 | Minimed Inc. | Method and kit for supplying a fluid to a subcutaneous placement site |
US5951521A (en) * | 1998-09-25 | 1999-09-14 | Minimed Inc. | Subcutaneous implantable sensor set having the capability to remove deliver fluids to an insertion site |
EP2229879A1 (en) | 1998-10-08 | 2010-09-22 | Medtronic MiniMed, Inc. | Telemetered characteristic monitor system |
US6591125B1 (en) | 2000-06-27 | 2003-07-08 | Therasense, Inc. | Small volume in vitro analyte sensor with diffusible or non-leachable redox mediator |
US6338790B1 (en) | 1998-10-08 | 2002-01-15 | Therasense, Inc. | Small volume in vitro analyte sensor with diffusible or non-leachable redox mediator |
US7766873B2 (en) | 1998-10-29 | 2010-08-03 | Medtronic Minimed, Inc. | Method and apparatus for detecting occlusions in an ambulatory infusion pump |
US7621893B2 (en) | 1998-10-29 | 2009-11-24 | Medtronic Minimed, Inc. | Methods and apparatuses for detecting occlusions in an ambulatory infusion pump |
ATE552771T1 (de) | 1999-02-25 | 2012-04-15 | Medtronic Minimed Inc | Prüfstecker und kabel für glucoseüberwachungsgerät |
US6424847B1 (en) | 1999-02-25 | 2002-07-23 | Medtronic Minimed, Inc. | Glucose monitor calibration methods |
US6689142B1 (en) | 1999-04-26 | 2004-02-10 | Scimed Life Systems, Inc. | Apparatus and methods for guiding a needle |
US6669663B1 (en) * | 1999-04-30 | 2003-12-30 | Medtronic, Inc. | Closed loop medicament pump |
US7806886B2 (en) | 1999-06-03 | 2010-10-05 | Medtronic Minimed, Inc. | Apparatus and method for controlling insulin infusion with state variable feedback |
CA2388689A1 (en) | 1999-06-17 | 2000-12-28 | Medtronic Minimed, Inc. | Characteristic monitor system for use with analyte sensor |
JP4801301B2 (ja) | 1999-06-18 | 2011-10-26 | アボット ダイアベティス ケア インコーポレイテッド | 物質移動が制限された生体内分析物センサー |
US6368274B1 (en) | 1999-07-01 | 2002-04-09 | Medtronic Minimed, Inc. | Reusable analyte sensor site and method of using the same |
US6251083B1 (en) | 1999-09-07 | 2001-06-26 | Amira Medical | Interstitial fluid methods and devices for determination of an analyte in the body |
AT408182B (de) | 1999-09-17 | 2001-09-25 | Schaupp Lukas Dipl Ing Dr Tech | Einrichtung zur in vivo-messung von grössen in lebenden organismen |
US6616819B1 (en) | 1999-11-04 | 2003-09-09 | Therasense, Inc. | Small volume in vitro analyte sensor and methods |
US6484045B1 (en) * | 2000-02-10 | 2002-11-19 | Medtronic Minimed, Inc. | Analyte sensor and method of making the same |
US7003336B2 (en) * | 2000-02-10 | 2006-02-21 | Medtronic Minimed, Inc. | Analyte sensor method of making the same |
DE60130536T2 (de) | 2000-02-10 | 2008-06-26 | Medtronic MiniMed, Inc., Northridge | Analytensensor |
US7890295B2 (en) | 2000-02-23 | 2011-02-15 | Medtronic Minimed, Inc. | Real time self-adjusting calibration algorithm |
US6478775B1 (en) | 2000-10-02 | 2002-11-12 | Genyx Medical Inc. | Device for delivering non-biodegradable bulking composition to a urological site |
US6695860B1 (en) | 2000-11-13 | 2004-02-24 | Isense Corp. | Transcutaneous sensor insertion device |
US7052483B2 (en) * | 2000-12-19 | 2006-05-30 | Animas Corporation | Transcutaneous inserter for low-profile infusion sets |
US6560471B1 (en) | 2001-01-02 | 2003-05-06 | Therasense, Inc. | Analyte monitoring device and methods of use |
US6666821B2 (en) | 2001-01-08 | 2003-12-23 | Medtronic, Inc. | Sensor system |
EP1397068A2 (en) | 2001-04-02 | 2004-03-17 | Therasense, Inc. | Blood glucose tracking apparatus and methods |
US20030032874A1 (en) | 2001-07-27 | 2003-02-13 | Dexcom, Inc. | Sensor head for use with implantable devices |
US6702857B2 (en) | 2001-07-27 | 2004-03-09 | Dexcom, Inc. | Membrane for use with implantable devices |
US6827702B2 (en) | 2001-09-07 | 2004-12-07 | Medtronic Minimed, Inc. | Safety limits for closed-loop infusion pump control |
US7169155B2 (en) | 2001-12-14 | 2007-01-30 | Scimed Life Systems, Inc. | Methods and apparatus for guiding a needle |
US7399277B2 (en) * | 2001-12-27 | 2008-07-15 | Medtronic Minimed, Inc. | System for monitoring physiological characteristics |
US20080255438A1 (en) * | 2001-12-27 | 2008-10-16 | Medtronic Minimed, Inc. | System for monitoring physiological characteristics |
US20050027182A1 (en) * | 2001-12-27 | 2005-02-03 | Uzair Siddiqui | System for monitoring physiological characteristics |
US7022072B2 (en) * | 2001-12-27 | 2006-04-04 | Medtronic Minimed, Inc. | System for monitoring physiological characteristics |
US10080529B2 (en) | 2001-12-27 | 2018-09-25 | Medtronic Minimed, Inc. | System for monitoring physiological characteristics |
US7247162B1 (en) | 2002-01-14 | 2007-07-24 | Edwards Lifesciences Corporation | Direct access atherectomy devices |
US7004928B2 (en) | 2002-02-08 | 2006-02-28 | Rosedale Medical, Inc. | Autonomous, ambulatory analyte monitor or drug delivery device |
US8260393B2 (en) | 2003-07-25 | 2012-09-04 | Dexcom, Inc. | Systems and methods for replacing signal data artifacts in a glucose sensor data stream |
US7613491B2 (en) | 2002-05-22 | 2009-11-03 | Dexcom, Inc. | Silicone based membranes for use in implantable glucose sensors |
US8010174B2 (en) | 2003-08-22 | 2011-08-30 | Dexcom, Inc. | Systems and methods for replacing signal artifacts in a glucose sensor data stream |
US9247901B2 (en) | 2003-08-22 | 2016-02-02 | Dexcom, Inc. | Systems and methods for replacing signal artifacts in a glucose sensor data stream |
US8364229B2 (en) | 2003-07-25 | 2013-01-29 | Dexcom, Inc. | Analyte sensors having a signal-to-noise ratio substantially unaffected by non-constant noise |
US7828728B2 (en) | 2003-07-25 | 2010-11-09 | Dexcom, Inc. | Analyte sensor |
US9282925B2 (en) | 2002-02-12 | 2016-03-15 | Dexcom, Inc. | Systems and methods for replacing signal artifacts in a glucose sensor data stream |
US7497827B2 (en) | 2004-07-13 | 2009-03-03 | Dexcom, Inc. | Transcutaneous analyte sensor |
US6936006B2 (en) * | 2002-03-22 | 2005-08-30 | Novo Nordisk, A/S | Atraumatic insertion of a subcutaneous device |
US7226978B2 (en) | 2002-05-22 | 2007-06-05 | Dexcom, Inc. | Techniques to improve polyurethane membranes for implantable glucose sensors |
US7278983B2 (en) | 2002-07-24 | 2007-10-09 | Medtronic Minimed, Inc. | Physiological monitoring device for controlling a medication infusion device |
US8512276B2 (en) | 2002-07-24 | 2013-08-20 | Medtronic Minimed, Inc. | System for providing blood glucose measurements to an infusion device |
US20040068230A1 (en) | 2002-07-24 | 2004-04-08 | Medtronic Minimed, Inc. | System for providing blood glucose measurements to an infusion device |
US20040061232A1 (en) * | 2002-09-27 | 2004-04-01 | Medtronic Minimed, Inc. | Multilayer substrate |
US8003513B2 (en) * | 2002-09-27 | 2011-08-23 | Medtronic Minimed, Inc. | Multilayer circuit devices and manufacturing methods using electroplated sacrificial structures |
US7993108B2 (en) | 2002-10-09 | 2011-08-09 | Abbott Diabetes Care Inc. | Variable volume, shape memory actuated insulin dispensing pump |
EP2383470A1 (en) | 2002-10-09 | 2011-11-02 | Abbott Diabetes Care Inc. | Plunger pump actuated by a shape memory element |
US7727181B2 (en) | 2002-10-09 | 2010-06-01 | Abbott Diabetes Care Inc. | Fluid delivery device with autocalibration |
US7381184B2 (en) | 2002-11-05 | 2008-06-03 | Abbott Diabetes Care Inc. | Sensor inserter assembly |
US7572237B2 (en) | 2002-11-06 | 2009-08-11 | Abbott Diabetes Care Inc. | Automatic biological analyte testing meter with integrated lancing device and methods of use |
WO2004044557A2 (en) * | 2002-11-12 | 2004-05-27 | Argose, Inc. | Non-invasive measurement of analytes |
US20040106163A1 (en) * | 2002-11-12 | 2004-06-03 | Workman Jerome James | Non-invasive measurement of analytes |
US20040122353A1 (en) | 2002-12-19 | 2004-06-24 | Medtronic Minimed, Inc. | Relay device for transferring information between a sensor system and a fluid delivery system |
AU2003303597A1 (en) | 2002-12-31 | 2004-07-29 | Therasense, Inc. | Continuous glucose monitoring system and methods of use |
EP1599124B1 (en) * | 2003-02-07 | 2010-03-31 | Alfred E. Mann Institute for Biomedical Engineering at the University of Southern California | Surgical drain with sensors for tissue monitoring |
US7052652B2 (en) | 2003-03-24 | 2006-05-30 | Rosedale Medical, Inc. | Analyte concentration detection devices and methods |
US6965791B1 (en) | 2003-03-26 | 2005-11-15 | Sorenson Medical, Inc. | Implantable biosensor system, apparatus and method |
US7134999B2 (en) | 2003-04-04 | 2006-11-14 | Dexcom, Inc. | Optimized sensor geometry for an implantable glucose sensor |
US7679407B2 (en) | 2003-04-28 | 2010-03-16 | Abbott Diabetes Care Inc. | Method and apparatus for providing peak detection circuitry for data communication systems |
ATE474611T1 (de) * | 2003-05-08 | 2010-08-15 | Novo Nordisk As | Eine auf die haut aufbringbare injektionsvorrichtung mit abtrennbarem betätigungsteil zum einführen der nadel |
US7875293B2 (en) | 2003-05-21 | 2011-01-25 | Dexcom, Inc. | Biointerface membranes incorporating bioactive agents |
DE10325699B3 (de) * | 2003-06-06 | 2005-02-10 | Roche Diagnostics Gmbh | System zur Analyse einer zu untersuchenden Probe und Verwendung eines solchen Systems |
US8066639B2 (en) | 2003-06-10 | 2011-11-29 | Abbott Diabetes Care Inc. | Glucose measuring device for use in personal area network |
US9763609B2 (en) | 2003-07-25 | 2017-09-19 | Dexcom, Inc. | Analyte sensors having a signal-to-noise ratio substantially unaffected by non-constant noise |
US8423113B2 (en) | 2003-07-25 | 2013-04-16 | Dexcom, Inc. | Systems and methods for processing sensor data |
US7761130B2 (en) | 2003-07-25 | 2010-07-20 | Dexcom, Inc. | Dual electrode system for a continuous analyte sensor |
EP1648298A4 (en) | 2003-07-25 | 2010-01-13 | Dexcom Inc | OXYGEN-IMPROVED MEMBRANE SYSTEMS FOR IMPLANTABLE DEVICES |
US7778680B2 (en) | 2003-08-01 | 2010-08-17 | Dexcom, Inc. | System and methods for processing analyte sensor data |
US20190357827A1 (en) | 2003-08-01 | 2019-11-28 | Dexcom, Inc. | Analyte sensor |
US8369919B2 (en) | 2003-08-01 | 2013-02-05 | Dexcom, Inc. | Systems and methods for processing sensor data |
US8626257B2 (en) | 2003-08-01 | 2014-01-07 | Dexcom, Inc. | Analyte sensor |
US9135402B2 (en) | 2007-12-17 | 2015-09-15 | Dexcom, Inc. | Systems and methods for processing sensor data |
US8275437B2 (en) | 2003-08-01 | 2012-09-25 | Dexcom, Inc. | Transcutaneous analyte sensor |
US7774145B2 (en) | 2003-08-01 | 2010-08-10 | Dexcom, Inc. | Transcutaneous analyte sensor |
US8761856B2 (en) | 2003-08-01 | 2014-06-24 | Dexcom, Inc. | System and methods for processing analyte sensor data |
US7519408B2 (en) | 2003-11-19 | 2009-04-14 | Dexcom, Inc. | Integrated receiver for continuous analyte sensor |
US8845536B2 (en) | 2003-08-01 | 2014-09-30 | Dexcom, Inc. | Transcutaneous analyte sensor |
US8285354B2 (en) | 2003-08-01 | 2012-10-09 | Dexcom, Inc. | System and methods for processing analyte sensor data |
US7591801B2 (en) | 2004-02-26 | 2009-09-22 | Dexcom, Inc. | Integrated delivery device for continuous glucose sensor |
US20100168543A1 (en) | 2003-08-01 | 2010-07-01 | Dexcom, Inc. | System and methods for processing analyte sensor data |
US8160669B2 (en) | 2003-08-01 | 2012-04-17 | Dexcom, Inc. | Transcutaneous analyte sensor |
US8886273B2 (en) | 2003-08-01 | 2014-11-11 | Dexcom, Inc. | Analyte sensor |
US7920906B2 (en) | 2005-03-10 | 2011-04-05 | Dexcom, Inc. | System and methods for processing analyte sensor data for sensor calibration |
US20140121989A1 (en) | 2003-08-22 | 2014-05-01 | Dexcom, Inc. | Systems and methods for processing analyte sensor data |
US8233959B2 (en) | 2003-08-22 | 2012-07-31 | Dexcom, Inc. | Systems and methods for processing analyte sensor data |
US7299082B2 (en) | 2003-10-31 | 2007-11-20 | Abbott Diabetes Care, Inc. | Method of calibrating an analyte-measurement device, and associated methods, devices and systems |
USD902408S1 (en) | 2003-11-05 | 2020-11-17 | Abbott Diabetes Care Inc. | Analyte sensor control unit |
US7520867B2 (en) * | 2003-11-10 | 2009-04-21 | Medtronic Minimed, Inc. | Subcutaneous infusion set |
US7494481B2 (en) * | 2004-12-03 | 2009-02-24 | Medtronic Minimed, Inc. | Multi-position infusion set device and process |
US8615282B2 (en) | 2004-07-13 | 2013-12-24 | Dexcom, Inc. | Analyte sensor |
US9247900B2 (en) | 2004-07-13 | 2016-02-02 | Dexcom, Inc. | Analyte sensor |
US8425417B2 (en) | 2003-12-05 | 2013-04-23 | Dexcom, Inc. | Integrated device for continuous in vivo analyte detection and simultaneous control of an infusion device |
US11633133B2 (en) | 2003-12-05 | 2023-04-25 | Dexcom, Inc. | Dual electrode system for a continuous analyte sensor |
US8364231B2 (en) | 2006-10-04 | 2013-01-29 | Dexcom, Inc. | Analyte sensor |
US8423114B2 (en) | 2006-10-04 | 2013-04-16 | Dexcom, Inc. | Dual electrode system for a continuous analyte sensor |
US8774886B2 (en) | 2006-10-04 | 2014-07-08 | Dexcom, Inc. | Analyte sensor |
US8287453B2 (en) | 2003-12-05 | 2012-10-16 | Dexcom, Inc. | Analyte sensor |
EP2256493B1 (en) | 2003-12-05 | 2014-02-26 | DexCom, Inc. | Calibration techniques for a continuous analyte sensor |
US8364230B2 (en) | 2006-10-04 | 2013-01-29 | Dexcom, Inc. | Analyte sensor |
US8425416B2 (en) | 2006-10-04 | 2013-04-23 | Dexcom, Inc. | Analyte sensor |
EP1711791B1 (en) | 2003-12-09 | 2014-10-15 | DexCom, Inc. | Signal processing for continuous analyte sensor |
CA2556331A1 (en) | 2004-02-17 | 2005-09-29 | Therasense, Inc. | Method and system for providing data communication in continuous glucose monitoring and management system |
US8808228B2 (en) | 2004-02-26 | 2014-08-19 | Dexcom, Inc. | Integrated medicament delivery device for use with continuous analyte sensor |
WO2009048462A1 (en) | 2007-10-09 | 2009-04-16 | Dexcom, Inc. | Integrated insulin delivery system with continuous glucose sensor |
EP1727576B1 (en) | 2004-03-26 | 2009-03-04 | Unomedical A/S | Infusion set |
US8277713B2 (en) | 2004-05-03 | 2012-10-02 | Dexcom, Inc. | Implantable analyte sensor |
US8792955B2 (en) | 2004-05-03 | 2014-07-29 | Dexcom, Inc. | Transcutaneous analyte sensor |
EP2256494B1 (en) | 2004-06-03 | 2017-01-11 | Medtronic MiniMed, Inc. | System for monitoring physiological characteristics according to the user biological state |
CA2858901C (en) | 2004-06-04 | 2024-01-16 | Carolyn Anderson | Diabetes care host-client architecture and data management system |
US8565848B2 (en) | 2004-07-13 | 2013-10-22 | Dexcom, Inc. | Transcutaneous analyte sensor |
US20060016700A1 (en) | 2004-07-13 | 2006-01-26 | Dexcom, Inc. | Transcutaneous analyte sensor |
US7783333B2 (en) | 2004-07-13 | 2010-08-24 | Dexcom, Inc. | Transcutaneous medical device with variable stiffness |
US20070045902A1 (en) | 2004-07-13 | 2007-03-01 | Brauker James H | Analyte sensor |
EP3666187B1 (en) * | 2004-07-13 | 2021-05-26 | DexCom, Inc. | Transcutaneous analyte sensor |
US8452368B2 (en) | 2004-07-13 | 2013-05-28 | Dexcom, Inc. | Transcutaneous analyte sensor |
US7344500B2 (en) | 2004-07-27 | 2008-03-18 | Medtronic Minimed, Inc. | Sensing system with auxiliary display |
US8062250B2 (en) | 2004-08-10 | 2011-11-22 | Unomedical A/S | Cannula device |
US7468033B2 (en) * | 2004-09-08 | 2008-12-23 | Medtronic Minimed, Inc. | Blood contacting sensor |
US7146939B2 (en) * | 2004-09-14 | 2006-12-12 | Federal-Mogul Worldwide, Inc. | Anti-cavitation diesel cylinder liner |
US7303543B1 (en) | 2004-12-03 | 2007-12-04 | Medtronic Minimed, Inc. | Medication infusion set |
US8333714B2 (en) | 2006-09-10 | 2012-12-18 | Abbott Diabetes Care Inc. | Method and system for providing an integrated analyte sensor insertion device and data processing unit |
US8571624B2 (en) | 2004-12-29 | 2013-10-29 | Abbott Diabetes Care Inc. | Method and apparatus for mounting a data transmission device in a communication system |
US9259175B2 (en) | 2006-10-23 | 2016-02-16 | Abbott Diabetes Care, Inc. | Flexible patch for fluid delivery and monitoring body analytes |
US9572534B2 (en) | 2010-06-29 | 2017-02-21 | Abbott Diabetes Care Inc. | Devices, systems and methods for on-skin or on-body mounting of medical devices |
US7883464B2 (en) | 2005-09-30 | 2011-02-08 | Abbott Diabetes Care Inc. | Integrated transmitter unit and sensor introducer mechanism and methods of use |
US9743862B2 (en) | 2011-03-31 | 2017-08-29 | Abbott Diabetes Care Inc. | Systems and methods for transcutaneously implanting medical devices |
US9636450B2 (en) | 2007-02-19 | 2017-05-02 | Udo Hoss | Pump system modular components for delivering medication and analyte sensing at seperate insertion sites |
US7731657B2 (en) | 2005-08-30 | 2010-06-08 | Abbott Diabetes Care Inc. | Analyte sensor introducer and methods of use |
US9351669B2 (en) | 2009-09-30 | 2016-05-31 | Abbott Diabetes Care Inc. | Interconnect for on-body analyte monitoring device |
US7697967B2 (en) | 2005-12-28 | 2010-04-13 | Abbott Diabetes Care Inc. | Method and apparatus for providing analyte sensor insertion |
US9398882B2 (en) | 2005-09-30 | 2016-07-26 | Abbott Diabetes Care Inc. | Method and apparatus for providing analyte sensor and data processing device |
US8613703B2 (en) | 2007-05-31 | 2013-12-24 | Abbott Diabetes Care Inc. | Insertion devices and methods |
US8029441B2 (en) | 2006-02-28 | 2011-10-04 | Abbott Diabetes Care Inc. | Analyte sensor transmitter unit configuration for a data monitoring and management system |
US9788771B2 (en) | 2006-10-23 | 2017-10-17 | Abbott Diabetes Care Inc. | Variable speed sensor insertion devices and methods of use |
US10226207B2 (en) | 2004-12-29 | 2019-03-12 | Abbott Diabetes Care Inc. | Sensor inserter having introducer |
US8512243B2 (en) | 2005-09-30 | 2013-08-20 | Abbott Diabetes Care Inc. | Integrated introducer and transmitter assembly and methods of use |
US20090105569A1 (en) | 2006-04-28 | 2009-04-23 | Abbott Diabetes Care, Inc. | Introducer Assembly and Methods of Use |
US20070027381A1 (en) * | 2005-07-29 | 2007-02-01 | Therasense, Inc. | Inserter and methods of use |
US7704229B2 (en) | 2005-02-03 | 2010-04-27 | Medtronic Minimed, Inc. | Insertion device |
US20090076360A1 (en) | 2007-09-13 | 2009-03-19 | Dexcom, Inc. | Transcutaneous analyte sensor |
US8133178B2 (en) | 2006-02-22 | 2012-03-13 | Dexcom, Inc. | Analyte sensor |
US7985199B2 (en) | 2005-03-17 | 2011-07-26 | Unomedical A/S | Gateway system |
US20060224141A1 (en) | 2005-03-21 | 2006-10-05 | Abbott Diabetes Care, Inc. | Method and system for providing integrated medication infusion and analyte monitoring system |
US8744546B2 (en) | 2005-05-05 | 2014-06-03 | Dexcom, Inc. | Cellulosic-based resistance domain for an analyte sensor |
US8060174B2 (en) | 2005-04-15 | 2011-11-15 | Dexcom, Inc. | Analyte sensing biointerface |
US8112240B2 (en) | 2005-04-29 | 2012-02-07 | Abbott Diabetes Care Inc. | Method and apparatus for providing leak detection in data monitoring and management systems |
US20060253085A1 (en) * | 2005-05-06 | 2006-11-09 | Medtronic Minimed, Inc. | Dual insertion set |
US7768408B2 (en) | 2005-05-17 | 2010-08-03 | Abbott Diabetes Care Inc. | Method and system for providing data management in data monitoring system |
US7620437B2 (en) | 2005-06-03 | 2009-11-17 | Abbott Diabetes Care Inc. | Method and apparatus for providing rechargeable power in data monitoring and management systems |
US20060281187A1 (en) | 2005-06-13 | 2006-12-14 | Rosedale Medical, Inc. | Analyte detection devices and methods with hematocrit/volume correction and feedback control |
EP1733676B1 (de) * | 2005-06-17 | 2012-08-01 | F. Hoffmann-La Roche AG | Sensorsystem sowie Anordnung und Verfahren zur Überwachung eines Inhaltsstoffs, insbesondere Glucose in Körpergewebe |
US7737581B2 (en) | 2005-08-16 | 2010-06-15 | Medtronic Minimed, Inc. | Method and apparatus for predicting end of battery life |
US20090227855A1 (en) | 2005-08-16 | 2009-09-10 | Medtronic Minimed, Inc. | Controller device for an infusion pump |
EP1921980A4 (en) | 2005-08-31 | 2010-03-10 | Univ Virginia | IMPROVING THE PRECISION OF CONTINUOUS GLUCOSE SENSORS |
DK1762259T3 (da) | 2005-09-12 | 2011-01-03 | Unomedical As | Indføringsindretning til infusionssæt med en første og en anden fjederenhed |
US7713240B2 (en) | 2005-09-13 | 2010-05-11 | Medtronic Minimed, Inc. | Modular external infusion device |
US7725148B2 (en) | 2005-09-23 | 2010-05-25 | Medtronic Minimed, Inc. | Sensor with layered electrodes |
US9072476B2 (en) | 2005-09-23 | 2015-07-07 | Medtronic Minimed, Inc. | Flexible sensor apparatus |
US8382681B2 (en) | 2005-09-30 | 2013-02-26 | Intuity Medical, Inc. | Fully integrated wearable or handheld monitor |
US8801631B2 (en) | 2005-09-30 | 2014-08-12 | Intuity Medical, Inc. | Devices and methods for facilitating fluid transport |
US9521968B2 (en) * | 2005-09-30 | 2016-12-20 | Abbott Diabetes Care Inc. | Analyte sensor retention mechanism and methods of use |
US8880138B2 (en) | 2005-09-30 | 2014-11-04 | Abbott Diabetes Care Inc. | Device for channeling fluid and methods of use |
NL1030272C1 (nl) * | 2005-10-26 | 2007-04-27 | Variak | Inrichting voor het automatisch reguleren van de concentratie van glucose in het bloed van een diabetes-patient. |
US7583190B2 (en) | 2005-10-31 | 2009-09-01 | Abbott Diabetes Care Inc. | Method and apparatus for providing data communication in data monitoring and management systems |
US7766829B2 (en) | 2005-11-04 | 2010-08-03 | Abbott Diabetes Care Inc. | Method and system for providing basal profile modification in analyte monitoring and management systems |
CA2634335A1 (en) | 2005-12-23 | 2007-06-28 | Unomedical A/S | Device for administration |
EP1968432A4 (en) | 2005-12-28 | 2009-10-21 | Abbott Diabetes Care Inc | INTRODUCTION OF A MEDICAL DEVICE |
US11298058B2 (en) * | 2005-12-28 | 2022-04-12 | Abbott Diabetes Care Inc. | Method and apparatus for providing analyte sensor insertion |
US7985330B2 (en) | 2005-12-30 | 2011-07-26 | Medtronic Minimed, Inc. | Method and system for detecting age, hydration, and functional states of sensors using electrochemical impedance spectroscopy |
US20070169533A1 (en) | 2005-12-30 | 2007-07-26 | Medtronic Minimed, Inc. | Methods and systems for detecting the hydration of sensors |
US20070173712A1 (en) | 2005-12-30 | 2007-07-26 | Medtronic Minimed, Inc. | Method of and system for stabilization of sensors |
US8114268B2 (en) | 2005-12-30 | 2012-02-14 | Medtronic Minimed, Inc. | Method and system for remedying sensor malfunctions detected by electrochemical impedance spectroscopy |
US8114269B2 (en) | 2005-12-30 | 2012-02-14 | Medtronic Minimed, Inc. | System and method for determining the point of hydration and proper time to apply potential to a glucose sensor |
US7774038B2 (en) | 2005-12-30 | 2010-08-10 | Medtronic Minimed, Inc. | Real-time self-calibrating sensor system and method |
US9757061B2 (en) | 2006-01-17 | 2017-09-12 | Dexcom, Inc. | Low oxygen in vivo analyte sensor |
US7736310B2 (en) | 2006-01-30 | 2010-06-15 | Abbott Diabetes Care Inc. | On-body medical device securement |
US8344966B2 (en) | 2006-01-31 | 2013-01-01 | Abbott Diabetes Care Inc. | Method and system for providing a fault tolerant display unit in an electronic device |
US7885698B2 (en) | 2006-02-28 | 2011-02-08 | Abbott Diabetes Care Inc. | Method and system for providing continuous calibration of implantable analyte sensors |
JP5038334B2 (ja) | 2006-02-28 | 2012-10-03 | ウノメディカル アクティーゼルスカブ | 注入部品のための挿入具及び針保護具を備えた注入部品 |
US7826879B2 (en) | 2006-02-28 | 2010-11-02 | Abbott Diabetes Care Inc. | Analyte sensors and methods of use |
US8473022B2 (en) | 2008-01-31 | 2013-06-25 | Abbott Diabetes Care Inc. | Analyte sensor with time lag compensation |
US9675290B2 (en) | 2012-10-30 | 2017-06-13 | Abbott Diabetes Care Inc. | Sensitivity calibration of in vivo sensors used to measure analyte concentration |
US7620438B2 (en) | 2006-03-31 | 2009-11-17 | Abbott Diabetes Care Inc. | Method and system for powering an electronic device |
US9392969B2 (en) | 2008-08-31 | 2016-07-19 | Abbott Diabetes Care Inc. | Closed loop control and signal attenuation detection |
US8583205B2 (en) | 2008-03-28 | 2013-11-12 | Abbott Diabetes Care Inc. | Analyte sensor calibration management |
US8478557B2 (en) | 2009-07-31 | 2013-07-02 | Abbott Diabetes Care Inc. | Method and apparatus for providing analyte monitoring system calibration accuracy |
US7801582B2 (en) | 2006-03-31 | 2010-09-21 | Abbott Diabetes Care Inc. | Analyte monitoring and management system and methods therefor |
US7653425B2 (en) | 2006-08-09 | 2010-01-26 | Abbott Diabetes Care Inc. | Method and system for providing calibration of an analyte sensor in an analyte monitoring system |
US7618369B2 (en) | 2006-10-02 | 2009-11-17 | Abbott Diabetes Care Inc. | Method and system for dynamically updating calibration parameters for an analyte sensor |
US8219173B2 (en) | 2008-09-30 | 2012-07-10 | Abbott Diabetes Care Inc. | Optimizing analyte sensor calibration |
US8140312B2 (en) | 2007-05-14 | 2012-03-20 | Abbott Diabetes Care Inc. | Method and system for determining analyte levels |
US8346335B2 (en) | 2008-03-28 | 2013-01-01 | Abbott Diabetes Care Inc. | Analyte sensor calibration management |
US8374668B1 (en) | 2007-10-23 | 2013-02-12 | Abbott Diabetes Care Inc. | Analyte sensor with lag compensation |
US7630748B2 (en) | 2006-10-25 | 2009-12-08 | Abbott Diabetes Care Inc. | Method and system for providing analyte monitoring |
US8226891B2 (en) | 2006-03-31 | 2012-07-24 | Abbott Diabetes Care Inc. | Analyte monitoring devices and methods therefor |
US8224415B2 (en) | 2009-01-29 | 2012-07-17 | Abbott Diabetes Care Inc. | Method and device for providing offset model based calibration for analyte sensor |
US8073008B2 (en) | 2006-04-28 | 2011-12-06 | Medtronic Minimed, Inc. | Subnetwork synchronization and variable transmit synchronization techniques for a wireless medical device network |
US7942844B2 (en) | 2006-04-28 | 2011-05-17 | Medtronic Minimed, Inc. | Remote monitoring for networked fluid infusion systems |
WO2007143225A2 (en) | 2006-06-07 | 2007-12-13 | Abbott Diabetes Care, Inc. | Analyte monitoring system and method |
AU2007256561B2 (en) * | 2006-06-07 | 2012-07-19 | Unomedical A/S | Inserter for transcutaneous sensor |
CN101489604B (zh) | 2006-06-09 | 2012-05-23 | 优诺医疗有限公司 | 安装垫 |
KR20090037492A (ko) | 2006-08-02 | 2009-04-15 | 우노메디컬 에이/에스 | 캐뉼라와 약물공급장치 |
EP1894526A1 (de) | 2006-09-04 | 2008-03-05 | F. Hoffmann-la Roche AG | Lanzette |
US8275438B2 (en) | 2006-10-04 | 2012-09-25 | Dexcom, Inc. | Analyte sensor |
US8447376B2 (en) | 2006-10-04 | 2013-05-21 | Dexcom, Inc. | Analyte sensor |
US8298142B2 (en) | 2006-10-04 | 2012-10-30 | Dexcom, Inc. | Analyte sensor |
US8449464B2 (en) | 2006-10-04 | 2013-05-28 | Dexcom, Inc. | Analyte sensor |
US7831287B2 (en) | 2006-10-04 | 2010-11-09 | Dexcom, Inc. | Dual electrode system for a continuous analyte sensor |
US8562528B2 (en) | 2006-10-04 | 2013-10-22 | Dexcom, Inc. | Analyte sensor |
US8478377B2 (en) | 2006-10-04 | 2013-07-02 | Dexcom, Inc. | Analyte sensor |
BRPI0718119A2 (pt) | 2006-10-26 | 2014-07-08 | Abbott Diabetes Care Inc | Métodos, sistemas e programas de computador para a detecção em tempo real do declínio de sensibilidade em sensores de analito |
EP1917990A1 (en) | 2006-10-31 | 2008-05-07 | Unomedical A/S | Infusion set |
US8579853B2 (en) | 2006-10-31 | 2013-11-12 | Abbott Diabetes Care Inc. | Infusion devices and methods |
US20080119705A1 (en) | 2006-11-17 | 2008-05-22 | Medtronic Minimed, Inc. | Systems and Methods for Diabetes Management Using Consumer Electronic Devices |
US8696570B2 (en) * | 2006-11-28 | 2014-04-15 | Roche Diagnostics Operations Inc. | Insertion device and method for inserting a subcutaneously insertable element into body |
US7946985B2 (en) * | 2006-12-29 | 2011-05-24 | Medtronic Minimed, Inc. | Method and system for providing sensor redundancy |
US10154804B2 (en) | 2007-01-31 | 2018-12-18 | Medtronic Minimed, Inc. | Model predictive method and system for controlling and supervising insulin infusion |
US20080199894A1 (en) | 2007-02-15 | 2008-08-21 | Abbott Diabetes Care, Inc. | Device and method for automatic data acquisition and/or detection |
US8121857B2 (en) | 2007-02-15 | 2012-02-21 | Abbott Diabetes Care Inc. | Device and method for automatic data acquisition and/or detection |
US8930203B2 (en) | 2007-02-18 | 2015-01-06 | Abbott Diabetes Care Inc. | Multi-function analyte test device and methods therefor |
US8732188B2 (en) | 2007-02-18 | 2014-05-20 | Abbott Diabetes Care Inc. | Method and system for providing contextual based medication dosage determination |
US8123686B2 (en) | 2007-03-01 | 2012-02-28 | Abbott Diabetes Care Inc. | Method and apparatus for providing rolling data in communication systems |
US10111608B2 (en) | 2007-04-14 | 2018-10-30 | Abbott Diabetes Care Inc. | Method and apparatus for providing data processing and control in medical communication system |
ES2461090T3 (es) | 2007-04-14 | 2014-05-16 | Abbott Diabetes Care Inc. | Procedimiento y aparato para proporcionar tratamiento y control de datos en un sistema de comunicación médica |
WO2008130897A2 (en) | 2007-04-14 | 2008-10-30 | Abbott Diabetes Care, Inc. | Method and apparatus for providing data processing and control in medical communication system |
WO2008130898A1 (en) | 2007-04-14 | 2008-10-30 | Abbott Diabetes Care, Inc. | Method and apparatus for providing data processing and control in medical communication system |
WO2008130895A2 (en) | 2007-04-14 | 2008-10-30 | Abbott Diabetes Care, Inc. | Method and apparatus for providing dynamic multi-stage signal amplification in a medical device |
WO2008128210A1 (en) | 2007-04-14 | 2008-10-23 | Abbott Diabetes Care, Inc. | Method and apparatus for providing data processing and control in medical communication system |
US20080269714A1 (en) | 2007-04-25 | 2008-10-30 | Medtronic Minimed, Inc. | Closed loop/semi-closed loop therapy modification system |
US8456301B2 (en) | 2007-05-08 | 2013-06-04 | Abbott Diabetes Care Inc. | Analyte monitoring system and methods |
US7928850B2 (en) | 2007-05-08 | 2011-04-19 | Abbott Diabetes Care Inc. | Analyte monitoring system and methods |
US8461985B2 (en) | 2007-05-08 | 2013-06-11 | Abbott Diabetes Care Inc. | Analyte monitoring system and methods |
US8665091B2 (en) | 2007-05-08 | 2014-03-04 | Abbott Diabetes Care Inc. | Method and device for determining elapsed sensor life |
US8260558B2 (en) | 2007-05-14 | 2012-09-04 | Abbott Diabetes Care Inc. | Method and apparatus for providing data processing and control in a medical communication system |
US7996158B2 (en) | 2007-05-14 | 2011-08-09 | Abbott Diabetes Care Inc. | Method and apparatus for providing data processing and control in a medical communication system |
US8560038B2 (en) | 2007-05-14 | 2013-10-15 | Abbott Diabetes Care Inc. | Method and apparatus for providing data processing and control in a medical communication system |
US9125548B2 (en) | 2007-05-14 | 2015-09-08 | Abbott Diabetes Care Inc. | Method and apparatus for providing data processing and control in a medical communication system |
US8444560B2 (en) | 2007-05-14 | 2013-05-21 | Abbott Diabetes Care Inc. | Method and apparatus for providing data processing and control in a medical communication system |
US8239166B2 (en) | 2007-05-14 | 2012-08-07 | Abbott Diabetes Care Inc. | Method and apparatus for providing data processing and control in a medical communication system |
US10002233B2 (en) | 2007-05-14 | 2018-06-19 | Abbott Diabetes Care Inc. | Method and apparatus for providing data processing and control in a medical communication system |
US8600681B2 (en) | 2007-05-14 | 2013-12-03 | Abbott Diabetes Care Inc. | Method and apparatus for providing data processing and control in a medical communication system |
US8103471B2 (en) | 2007-05-14 | 2012-01-24 | Abbott Diabetes Care Inc. | Method and apparatus for providing data processing and control in a medical communication system |
US20200037874A1 (en) | 2007-05-18 | 2020-02-06 | Dexcom, Inc. | Analyte sensors having a signal-to-noise ratio substantially unaffected by non-constant noise |
US20080306434A1 (en) | 2007-06-08 | 2008-12-11 | Dexcom, Inc. | Integrated medicament delivery device for use with continuous analyte sensor |
JP2010530266A (ja) | 2007-06-20 | 2010-09-09 | ウノメディカル アクティーゼルスカブ | カテーテル並びにカテーテルの製造方法及び装置 |
WO2008157820A1 (en) | 2007-06-21 | 2008-12-24 | Abbott Diabetes Care, Inc. | Health management devices and methods |
JP2010531169A (ja) | 2007-06-21 | 2010-09-24 | アボット ダイアベティス ケア インコーポレイテッド | 健康監視装置 |
US8002752B2 (en) * | 2007-06-25 | 2011-08-23 | Medingo, Ltd. | Protector apparatus |
US8160900B2 (en) | 2007-06-29 | 2012-04-17 | Abbott Diabetes Care Inc. | Analyte monitoring and management device and method to analyze the frequency of user interaction with the device |
US8430850B2 (en) | 2007-07-03 | 2013-04-30 | Unomedical A/S | Inserter having bistable equilibrium states |
KR20100062991A (ko) | 2007-07-10 | 2010-06-10 | 우노메디컬 에이/에스 | 두 개의 스프링을 갖는 인서터 |
US8246588B2 (en) | 2007-07-18 | 2012-08-21 | Unomedical A/S | Insertion device with pivoting action |
US7768386B2 (en) | 2007-07-31 | 2010-08-03 | Abbott Diabetes Care Inc. | Method and apparatus for providing data processing and control in a medical communication system |
US8834366B2 (en) | 2007-07-31 | 2014-09-16 | Abbott Diabetes Care Inc. | Method and apparatus for providing analyte sensor calibration |
US8971981B2 (en) * | 2007-08-01 | 2015-03-03 | Roche Diagnostics Operations, Inc. | Device and method for facilitating infusion of therapeutic fluids and sensing of bodily analytes |
US20120046533A1 (en) | 2007-08-29 | 2012-02-23 | Medtronic Minimed, Inc. | Combined sensor and infusion sets |
US9968742B2 (en) * | 2007-08-29 | 2018-05-15 | Medtronic Minimed, Inc. | Combined sensor and infusion set using separated sites |
US8057486B2 (en) * | 2007-09-18 | 2011-11-15 | Bioness Inc. | Apparatus and method for inserting implants into the body |
US8216138B1 (en) | 2007-10-23 | 2012-07-10 | Abbott Diabetes Care Inc. | Correlation of alternative site blood and interstitial fluid glucose concentrations to venous glucose concentration |
US8409093B2 (en) | 2007-10-23 | 2013-04-02 | Abbott Diabetes Care Inc. | Assessing measures of glycemic variability |
US8377031B2 (en) | 2007-10-23 | 2013-02-19 | Abbott Diabetes Care Inc. | Closed loop control system with safety parameters and methods |
US8000918B2 (en) | 2007-10-23 | 2011-08-16 | Edwards Lifesciences Corporation | Monitoring and compensating for temperature-related error in an electrochemical sensor |
US8417312B2 (en) | 2007-10-25 | 2013-04-09 | Dexcom, Inc. | Systems and methods for processing sensor data |
US7783442B2 (en) * | 2007-10-31 | 2010-08-24 | Medtronic Minimed, Inc. | System and methods for calibrating physiological characteristic sensors |
US20090188811A1 (en) | 2007-11-28 | 2009-07-30 | Edwards Lifesciences Corporation | Preparation and maintenance of sensors |
US9839395B2 (en) | 2007-12-17 | 2017-12-12 | Dexcom, Inc. | Systems and methods for processing sensor data |
US20090164239A1 (en) | 2007-12-19 | 2009-06-25 | Abbott Diabetes Care, Inc. | Dynamic Display Of Glucose Information |
US8313467B2 (en) | 2007-12-27 | 2012-11-20 | Medtronic Minimed, Inc. | Reservoir pressure equalization systems and methods |
US8364277B2 (en) * | 2008-01-10 | 2013-01-29 | Bioness Inc. | Methods and apparatus for implanting electronic implants within the body |
US8915866B2 (en) | 2008-01-18 | 2014-12-23 | Warsaw Orthopedic, Inc. | Implantable sensor and associated methods |
US10898643B2 (en) | 2008-02-13 | 2021-01-26 | Unomedical A/S | Sealing between a cannula part and a fluid path |
CA2715667A1 (en) | 2008-02-20 | 2009-08-27 | Unomedical A/S | Insertion device with horizontally moving part |
EP2252196A4 (en) | 2008-02-21 | 2013-05-15 | Dexcom Inc | SYSTEMS AND METHOD FOR PROCESSING, TRANSMITTING AND DISPLAYING SENSOR DATA |
CA2968779C (en) * | 2008-03-17 | 2020-02-25 | Waveform Technologies, Inc. | Analyte sensor subassembly and methods and apparatuses for inserting an analyte sensor associated with same |
US8396528B2 (en) | 2008-03-25 | 2013-03-12 | Dexcom, Inc. | Analyte sensor |
US11730407B2 (en) | 2008-03-28 | 2023-08-22 | Dexcom, Inc. | Polymer membranes for continuous analyte sensors |
US8583204B2 (en) | 2008-03-28 | 2013-11-12 | Dexcom, Inc. | Polymer membranes for continuous analyte sensors |
US8682408B2 (en) | 2008-03-28 | 2014-03-25 | Dexcom, Inc. | Polymer membranes for continuous analyte sensors |
EP2262543B1 (en) | 2008-04-10 | 2015-07-08 | Abbott Diabetes Care Inc. | Method and system for sterilizing an analyte sensor |
TWI394580B (zh) | 2008-04-28 | 2013-05-01 | Halozyme Inc | 超快起作用胰島素組成物 |
US9295786B2 (en) | 2008-05-28 | 2016-03-29 | Medtronic Minimed, Inc. | Needle protective device for subcutaneous sensors |
CA2725264C (en) | 2008-05-30 | 2017-06-20 | Intuity Medical, Inc. | Body fluid sampling device -- sampling site interface |
US8924159B2 (en) | 2008-05-30 | 2014-12-30 | Abbott Diabetes Care Inc. | Method and apparatus for providing glycemic control |
US8591410B2 (en) | 2008-05-30 | 2013-11-26 | Abbott Diabetes Care Inc. | Method and apparatus for providing glycemic control |
US7826382B2 (en) | 2008-05-30 | 2010-11-02 | Abbott Diabetes Care Inc. | Close proximity communication device and methods |
JP5642066B2 (ja) | 2008-06-06 | 2014-12-17 | インテュイティ メディカル インコーポレイテッド | 体液の試料内に含まれている検体の存在または濃度を決定する検定を行う方法および装置 |
CA2726071C (en) | 2008-06-06 | 2024-01-02 | Intuity Medical, Inc. | Blood glucose monitoring device |
US8876755B2 (en) | 2008-07-14 | 2014-11-04 | Abbott Diabetes Care Inc. | Closed loop control system interface and methods |
US8494650B2 (en) * | 2008-08-07 | 2013-07-23 | Bioness, Inc. | Insertion tools and methods for an electrical stimulation implant |
US8900431B2 (en) | 2008-08-27 | 2014-12-02 | Edwards Lifesciences Corporation | Analyte sensor |
US20100057040A1 (en) | 2008-08-31 | 2010-03-04 | Abbott Diabetes Care, Inc. | Robust Closed Loop Control And Methods |
US8734422B2 (en) | 2008-08-31 | 2014-05-27 | Abbott Diabetes Care Inc. | Closed loop control with improved alarm functions |
US8622988B2 (en) | 2008-08-31 | 2014-01-07 | Abbott Diabetes Care Inc. | Variable rate closed loop control and methods |
US9943644B2 (en) | 2008-08-31 | 2018-04-17 | Abbott Diabetes Care Inc. | Closed loop control with reference measurement and methods thereof |
US8560039B2 (en) | 2008-09-19 | 2013-10-15 | Dexcom, Inc. | Particle-containing membrane and particulate electrode for analyte sensors |
US8986208B2 (en) | 2008-09-30 | 2015-03-24 | Abbott Diabetes Care Inc. | Analyte sensor sensitivity attenuation mitigation |
DE102008053216A1 (de) | 2008-10-25 | 2010-05-06 | IHP GmbH - Innovations for High Performance Institut für innovative Mikroelektronik | Anordnung für einen transdermalen Sensor zur Erfassung und drahtlosen Übertragung von Messgrößen des Unterhautfettgewebes |
US8208973B2 (en) | 2008-11-05 | 2012-06-26 | Medtronic Minimed, Inc. | System and method for variable beacon timing with wireless devices |
US9326707B2 (en) | 2008-11-10 | 2016-05-03 | Abbott Diabetes Care Inc. | Alarm characterization for analyte monitoring devices and systems |
PL2384217T3 (pl) | 2008-12-22 | 2021-08-02 | Unomedical A/S | Urządzenie medyczne zawierające podkładkę samoprzylepną |
US20100160740A1 (en) * | 2008-12-24 | 2010-06-24 | Gary Cohen | Use of Patterns in a Therapy Management System |
US9330237B2 (en) * | 2008-12-24 | 2016-05-03 | Medtronic Minimed, Inc. | Pattern recognition and filtering in a therapy management system |
US10471207B2 (en) | 2008-12-29 | 2019-11-12 | Medtronic Minimed, Inc. | System and/or method for glucose sensor calibration |
US9289168B2 (en) | 2008-12-29 | 2016-03-22 | Medtronic Minimed, Inc. | System and/or method for glucose sensor calibration |
US20100168539A1 (en) | 2008-12-31 | 2010-07-01 | Palerm Cesar C | Method and/or system for estimating glycation of hemoglobin |
US8103456B2 (en) | 2009-01-29 | 2012-01-24 | Abbott Diabetes Care Inc. | Method and device for early signal attenuation detection using blood glucose measurements |
US8560082B2 (en) | 2009-01-30 | 2013-10-15 | Abbott Diabetes Care Inc. | Computerized determination of insulin pump therapy parameters using real time and retrospective data processing |
US9402544B2 (en) | 2009-02-03 | 2016-08-02 | Abbott Diabetes Care Inc. | Analyte sensor and apparatus for insertion of the sensor |
US20100213057A1 (en) | 2009-02-26 | 2010-08-26 | Benjamin Feldman | Self-Powered Analyte Sensor |
US9446194B2 (en) | 2009-03-27 | 2016-09-20 | Dexcom, Inc. | Methods and systems for promoting glucose management |
US8497777B2 (en) | 2009-04-15 | 2013-07-30 | Abbott Diabetes Care Inc. | Analyte monitoring system having an alert |
WO2010129375A1 (en) | 2009-04-28 | 2010-11-11 | Abbott Diabetes Care Inc. | Closed loop blood glucose control algorithm analysis |
US9226701B2 (en) | 2009-04-28 | 2016-01-05 | Abbott Diabetes Care Inc. | Error detection in critical repeating data in a wireless sensor system |
US8368556B2 (en) | 2009-04-29 | 2013-02-05 | Abbott Diabetes Care Inc. | Method and system for providing data communication in continuous glucose monitoring and management system |
EP2425209A4 (en) | 2009-04-29 | 2013-01-09 | Abbott Diabetes Care Inc | METHOD AND SYSTEM FOR REAL-TIME CALIBRATION OF AN ANALYTICAL SENSOR WITH RETROACTIVE FILLING |
US20100278738A1 (en) * | 2009-05-04 | 2010-11-04 | Sitzman Thomas J | Method to detect and monitor ischemia in transplanted organs and tissues |
WO2010138856A1 (en) | 2009-05-29 | 2010-12-02 | Abbott Diabetes Care Inc. | Medical device antenna systems having external antenna configurations |
US10376213B2 (en) * | 2009-06-30 | 2019-08-13 | Waveform Technologies, Inc. | System, method and apparatus for sensor insertion |
US8613892B2 (en) | 2009-06-30 | 2013-12-24 | Abbott Diabetes Care Inc. | Analyte meter with a moveable head and methods of using the same |
US8344847B2 (en) | 2009-07-09 | 2013-01-01 | Medtronic Minimed, Inc. | Coordination of control commands in a medical device system having at least one therapy delivery device and at least one wireless controller device |
EP4276652A3 (en) | 2009-07-23 | 2024-01-31 | Abbott Diabetes Care, Inc. | Real time management of data relating to physiological control of glucose levels |
EP4309580A3 (en) | 2009-07-23 | 2024-02-28 | Abbott Diabetes Care Inc. | Continuous analyte measurement system |
AU2010277755A1 (en) | 2009-07-30 | 2012-02-02 | Unomedical A/S | Inserter device with horizontal moving part |
US8758323B2 (en) | 2009-07-30 | 2014-06-24 | Tandem Diabetes Care, Inc. | Infusion pump system with disposable cartridge having pressure venting and pressure feedback |
RU2012108579A (ru) | 2009-08-07 | 2013-09-20 | Уномедикал А/С | Доставочное устройство с датчиком и одной или несколькими канюлями |
EP2473099A4 (en) | 2009-08-31 | 2015-01-14 | Abbott Diabetes Care Inc | ANALYTICAL SUBSTANCE MONITORING SYSTEM AND METHODS OF MANAGING ENERGY AND NOISE |
WO2011026147A1 (en) | 2009-08-31 | 2011-03-03 | Abbott Diabetes Care Inc. | Analyte signal processing device and methods |
US8514086B2 (en) | 2009-08-31 | 2013-08-20 | Abbott Diabetes Care Inc. | Displays for a medical device |
EP3001194B1 (en) | 2009-08-31 | 2019-04-17 | Abbott Diabetes Care, Inc. | Medical devices and methods |
US8487758B2 (en) | 2009-09-02 | 2013-07-16 | Medtronic Minimed, Inc. | Medical device having an intelligent alerting scheme, and related operating methods |
US9034172B2 (en) | 2009-09-08 | 2015-05-19 | Bayer Healthcare Llc | Electrochemical test sensor |
EP2482720A4 (en) | 2009-09-29 | 2014-04-23 | Abbott Diabetes Care Inc | METHOD AND APPARATUS FOR PROVIDING NOTIFICATION FUNCTION IN SUBSTANCE MONITORING SYSTEMS |
US8185181B2 (en) | 2009-10-30 | 2012-05-22 | Abbott Diabetes Care Inc. | Method and apparatus for detecting false hypoglycemic conditions |
EP2493538B1 (en) | 2009-10-30 | 2016-04-13 | Roche Diagnostics GmbH | Systems, methods and devices for adjusting the insertion depth of a cannula associated with a portable therapeutic device |
US8386042B2 (en) | 2009-11-03 | 2013-02-26 | Medtronic Minimed, Inc. | Omnidirectional accelerometer device and medical device incorporating same |
US8919605B2 (en) | 2009-11-30 | 2014-12-30 | Intuity Medical, Inc. | Calibration material delivery devices and methods |
US8574201B2 (en) | 2009-12-22 | 2013-11-05 | Medtronic Minimed, Inc. | Syringe piston with check valve seal |
US8755269B2 (en) | 2009-12-23 | 2014-06-17 | Medtronic Minimed, Inc. | Ranking and switching of wireless channels in a body area network of medical devices |
USD924406S1 (en) | 2010-02-01 | 2021-07-06 | Abbott Diabetes Care Inc. | Analyte sensor inserter |
WO2011112753A1 (en) | 2010-03-10 | 2011-09-15 | Abbott Diabetes Care Inc. | Systems, devices and methods for managing glucose levels |
US10448872B2 (en) * | 2010-03-16 | 2019-10-22 | Medtronic Minimed, Inc. | Analyte sensor apparatuses having improved electrode configurations and methods for making and using them |
CA3135001A1 (en) | 2010-03-24 | 2011-09-29 | Abbott Diabetes Care Inc. | Medical device inserters and processes of inserting and using medical devices |
BR112012024635A2 (pt) | 2010-03-30 | 2017-08-08 | Unomedical As | dispositivo médico |
US9215995B2 (en) | 2010-06-23 | 2015-12-22 | Medtronic Minimed, Inc. | Sensor systems having multiple probes and electrode arrays |
US8635046B2 (en) | 2010-06-23 | 2014-01-21 | Abbott Diabetes Care Inc. | Method and system for evaluating analyte sensor response characteristics |
WO2011162823A1 (en) | 2010-06-25 | 2011-12-29 | Intuity Medical, Inc. | Analyte monitoring methods and systems |
US10092229B2 (en) | 2010-06-29 | 2018-10-09 | Abbott Diabetes Care Inc. | Calibration of analyte measurement system |
US11064921B2 (en) | 2010-06-29 | 2021-07-20 | Abbott Diabetes Care Inc. | Devices, systems and methods for on-skin or on-body mounting of medical devices |
US10143357B2 (en) | 2010-08-10 | 2018-12-04 | Ronald Yamada | Endoscope gripping device |
US9125975B2 (en) | 2010-08-16 | 2015-09-08 | Becton, Dickinson And Company | User-actuated storage assembly for injection device |
EP2433663A1 (en) | 2010-09-27 | 2012-03-28 | Unomedical A/S | Insertion system |
EP2436412A1 (en) | 2010-10-04 | 2012-04-04 | Unomedical A/S | A sprinkler cannula |
EP2624745A4 (en) | 2010-10-07 | 2018-05-23 | Abbott Diabetes Care, Inc. | Analyte monitoring devices and methods |
US8562565B2 (en) | 2010-10-15 | 2013-10-22 | Medtronic Minimed, Inc. | Battery shock absorber for a portable medical device |
US8603033B2 (en) | 2010-10-15 | 2013-12-10 | Medtronic Minimed, Inc. | Medical device and related assembly having an offset element for a piezoelectric speaker |
US8603032B2 (en) | 2010-10-15 | 2013-12-10 | Medtronic Minimed, Inc. | Medical device with membrane keypad sealing element, and related manufacturing method |
US8479595B2 (en) | 2010-10-20 | 2013-07-09 | Medtronic Minimed, Inc. | Sensor assembly and medical device incorporating same |
US8474332B2 (en) | 2010-10-20 | 2013-07-02 | Medtronic Minimed, Inc. | Sensor assembly and medical device incorporating same |
US8495918B2 (en) | 2010-10-20 | 2013-07-30 | Medtronic Minimed, Inc. | Sensor assembly and medical device incorporating same |
US9402569B2 (en) | 2010-10-28 | 2016-08-02 | Medtronic Minimed, Inc. | System and/or method for glucose sensor calibration |
US8197444B1 (en) | 2010-12-22 | 2012-06-12 | Medtronic Minimed, Inc. | Monitoring the seating status of a fluid reservoir in a fluid infusion device |
US8628510B2 (en) | 2010-12-22 | 2014-01-14 | Medtronic Minimed, Inc. | Monitoring the operating health of a force sensor in a fluid infusion device |
US8690855B2 (en) * | 2010-12-22 | 2014-04-08 | Medtronic Minimed, Inc. | Fluid reservoir seating procedure for a fluid infusion device |
US8469942B2 (en) | 2010-12-22 | 2013-06-25 | Medtronic Minimed, Inc. | Occlusion detection for a fluid infusion device |
US8998851B2 (en) | 2011-02-09 | 2015-04-07 | Becton, Dickinson And Company | Compact spring inserter for drug deliver infusion set |
US8352034B2 (en) | 2011-02-18 | 2013-01-08 | Medtronic, Inc. | Medical device programmer with adjustable kickstand |
CN102762254B (zh) | 2011-02-18 | 2015-09-23 | 麦德托尼克公司 | 模块化医疗设备编程器 |
US9283318B2 (en) | 2011-02-22 | 2016-03-15 | Medtronic Minimed, Inc. | Flanged sealing element and needle guide pin assembly for a fluid infusion device having a needled fluid reservoir |
US9463309B2 (en) | 2011-02-22 | 2016-10-11 | Medtronic Minimed, Inc. | Sealing assembly and structure for a fluid infusion device having a needled fluid reservoir |
US8945068B2 (en) | 2011-02-22 | 2015-02-03 | Medtronic Minimed, Inc. | Fluid reservoir having a fluid delivery needle for a fluid infusion device |
US9393399B2 (en) | 2011-02-22 | 2016-07-19 | Medtronic Minimed, Inc. | Sealing assembly for a fluid reservoir of a fluid infusion device |
US10136845B2 (en) | 2011-02-28 | 2018-11-27 | Abbott Diabetes Care Inc. | Devices, systems, and methods associated with analyte monitoring devices and devices incorporating the same |
US8614596B2 (en) | 2011-02-28 | 2013-12-24 | Medtronic Minimed, Inc. | Systems and methods for initializing a voltage bus and medical devices incorporating same |
CN103619255B (zh) | 2011-02-28 | 2016-11-02 | 雅培糖尿病护理公司 | 与分析物监测装置关联的装置、系统和方法以及结合了它们的装置 |
US9101305B2 (en) | 2011-03-09 | 2015-08-11 | Medtronic Minimed, Inc. | Glucose sensor product and related manufacturing and packaging methods |
US9018893B2 (en) | 2011-03-18 | 2015-04-28 | Medtronic Minimed, Inc. | Power control techniques for an electronic device |
US8564447B2 (en) | 2011-03-18 | 2013-10-22 | Medtronic Minimed, Inc. | Battery life indication techniques for an electronic device |
JP6141827B2 (ja) | 2011-04-15 | 2017-06-07 | デックスコム・インコーポレーテッド | 検体を測定するシステムの作動方法及び該方法を実施するべく構成されたセンサシステム |
US20130011378A1 (en) | 2011-06-17 | 2013-01-10 | Tzung-Horng Yang | Stable formulations of a hyaluronan-degrading enzyme |
KR101676543B1 (ko) | 2011-06-17 | 2016-11-15 | 할로자임, 아이엔씨 | 히알루로난 분해효소를 이용한 연속적인 피하 인슐린 주입 방법 |
JP6223337B2 (ja) | 2011-08-03 | 2017-11-08 | インテュイティ メディカル インコーポレイテッド | 体液抽出測定器 |
US20130060106A1 (en) | 2011-09-06 | 2013-03-07 | Medtronic Minimed, Inc. | Optical sensing systems and methods |
US11197689B2 (en) | 2011-10-05 | 2021-12-14 | Unomedical A/S | Inserter for simultaneous insertion of multiple transcutaneous parts |
EP2583715A1 (en) | 2011-10-19 | 2013-04-24 | Unomedical A/S | Infusion tube system and method for manufacture |
US9440051B2 (en) | 2011-10-27 | 2016-09-13 | Unomedical A/S | Inserter for a multiplicity of subcutaneous parts |
US9069536B2 (en) | 2011-10-31 | 2015-06-30 | Abbott Diabetes Care Inc. | Electronic devices having integrated reset systems and methods thereof |
WO2013066849A1 (en) | 2011-10-31 | 2013-05-10 | Abbott Diabetes Care Inc. | Model based variable risk false glucose threshold alarm prevention mechanism |
AU2012335830B2 (en) | 2011-11-07 | 2017-05-04 | Abbott Diabetes Care Inc. | Analyte monitoring device and methods |
US8710993B2 (en) | 2011-11-23 | 2014-04-29 | Abbott Diabetes Care Inc. | Mitigating single point failure of devices in an analyte monitoring system and methods thereof |
US9317656B2 (en) | 2011-11-23 | 2016-04-19 | Abbott Diabetes Care Inc. | Compatibility mechanisms for devices in a continuous analyte monitoring system and methods thereof |
WO2013078426A2 (en) | 2011-11-25 | 2013-05-30 | Abbott Diabetes Care Inc. | Analyte monitoring system and methods of use |
CA3118810A1 (en) | 2011-12-11 | 2013-06-20 | Abbott Diabetes Care Inc. | Analyte sensor devices, connections, and methods |
US9610401B2 (en) | 2012-01-13 | 2017-04-04 | Medtronic Minimed, Inc. | Infusion set component with modular fluid channel element |
US8523803B1 (en) | 2012-03-20 | 2013-09-03 | Medtronic Minimed, Inc. | Motor health monitoring and medical device incorporating same |
US8603026B2 (en) | 2012-03-20 | 2013-12-10 | Medtronic Minimed, Inc. | Dynamic pulse-width modulation motor control and medical device incorporating same |
US8603027B2 (en) | 2012-03-20 | 2013-12-10 | Medtronic Minimed, Inc. | Occlusion detection using pulse-width modulation and medical device incorporating same |
US9615779B2 (en) | 2012-04-04 | 2017-04-11 | Dexcom, Inc. | Transcutaneous analyte sensors, applicators therefor, and associated methods |
EP2650032A1 (en) * | 2012-04-11 | 2013-10-16 | PharmaSens AG | Subcutaneous needle insertion mechanism |
US9180242B2 (en) | 2012-05-17 | 2015-11-10 | Tandem Diabetes Care, Inc. | Methods and devices for multiple fluid transfer |
US20130338630A1 (en) | 2012-06-07 | 2013-12-19 | Medtronic Minimed, Inc. | Diabetes therapy management system for recommending adjustments to an insulin infusion device |
US9333292B2 (en) | 2012-06-26 | 2016-05-10 | Medtronic Minimed, Inc. | Mechanically actuated fluid infusion device |
US8808269B2 (en) | 2012-08-21 | 2014-08-19 | Medtronic Minimed, Inc. | Reservoir plunger position monitoring and medical device incorporating same |
EP2890297B1 (en) | 2012-08-30 | 2018-04-11 | Abbott Diabetes Care, Inc. | Dropout detection in continuous analyte monitoring data during data excursions |
CN105169525B (zh) | 2012-08-30 | 2019-04-02 | 美敦力泌力美公司 | 用于闭环胰岛素输注系统的防护技术 |
US10130767B2 (en) | 2012-08-30 | 2018-11-20 | Medtronic Minimed, Inc. | Sensor model supervisor for a closed-loop insulin infusion system |
US9878096B2 (en) | 2012-08-30 | 2018-01-30 | Medtronic Minimed, Inc. | Generation of target glucose values for a closed-loop operating mode of an insulin infusion system |
US10496797B2 (en) | 2012-08-30 | 2019-12-03 | Medtronic Minimed, Inc. | Blood glucose validation for a closed-loop operating mode of an insulin infusion system |
US9364609B2 (en) | 2012-08-30 | 2016-06-14 | Medtronic Minimed, Inc. | Insulin on board compensation for a closed-loop insulin infusion system |
US9662445B2 (en) | 2012-08-30 | 2017-05-30 | Medtronic Minimed, Inc. | Regulating entry into a closed-loop operating mode of an insulin infusion system |
US9849239B2 (en) | 2012-08-30 | 2017-12-26 | Medtronic Minimed, Inc. | Generation and application of an insulin limit for a closed-loop operating mode of an insulin infusion system |
US9623179B2 (en) | 2012-08-30 | 2017-04-18 | Medtronic Minimed, Inc. | Safeguarding techniques for a closed-loop insulin infusion system |
US9968306B2 (en) | 2012-09-17 | 2018-05-15 | Abbott Diabetes Care Inc. | Methods and apparatuses for providing adverse condition notification with enhanced wireless communication range in analyte monitoring systems |
WO2014052136A1 (en) | 2012-09-26 | 2014-04-03 | Abbott Diabetes Care Inc. | Method and apparatus for improving lag correction during in vivo measurement of analyte concentration with analyte concentration variability and range data |
US9119528B2 (en) | 2012-10-30 | 2015-09-01 | Dexcom, Inc. | Systems and methods for providing sensitive and specific alarms |
US8870818B2 (en) | 2012-11-15 | 2014-10-28 | Medtronic Minimed, Inc. | Systems and methods for alignment and detection of a consumable component |
US9033924B2 (en) | 2013-01-18 | 2015-05-19 | Medtronic Minimed, Inc. | Systems for fluid reservoir retention |
US9107994B2 (en) | 2013-01-18 | 2015-08-18 | Medtronic Minimed, Inc. | Systems for fluid reservoir retention |
US9522223B2 (en) | 2013-01-18 | 2016-12-20 | Medtronic Minimed, Inc. | Systems for fluid reservoir retention |
US9308321B2 (en) | 2013-02-18 | 2016-04-12 | Medtronic Minimed, Inc. | Infusion device having gear assembly initialization |
US9173998B2 (en) | 2013-03-14 | 2015-11-03 | Tandem Diabetes Care, Inc. | System and method for detecting occlusions in an infusion pump |
US10433773B1 (en) | 2013-03-15 | 2019-10-08 | Abbott Diabetes Care Inc. | Noise rejection methods and apparatus for sparsely sampled analyte sensor data |
US9474475B1 (en) | 2013-03-15 | 2016-10-25 | Abbott Diabetes Care Inc. | Multi-rate analyte sensor data collection with sample rate configurable signal processing |
WO2014152034A1 (en) | 2013-03-15 | 2014-09-25 | Abbott Diabetes Care Inc. | Sensor fault detection using analyte sensor data pattern comparison |
US8920381B2 (en) | 2013-04-12 | 2014-12-30 | Medtronic Minimed, Inc. | Infusion set with improved bore configuration |
CA2912283A1 (en) | 2013-06-21 | 2014-12-21 | Intuity Medical, Inc. | Analyte monitoring system with audible feedback |
US9433731B2 (en) | 2013-07-19 | 2016-09-06 | Medtronic Minimed, Inc. | Detecting unintentional motor motion and infusion device incorporating same |
US9402949B2 (en) | 2013-08-13 | 2016-08-02 | Medtronic Minimed, Inc. | Detecting conditions associated with medical device operations using matched filters |
US9889257B2 (en) | 2013-08-21 | 2018-02-13 | Medtronic Minimed, Inc. | Systems and methods for updating medical devices |
US9880528B2 (en) | 2013-08-21 | 2018-01-30 | Medtronic Minimed, Inc. | Medical devices and related updating methods and systems |
US9259528B2 (en) | 2013-08-22 | 2016-02-16 | Medtronic Minimed, Inc. | Fluid infusion device with safety coupling |
US9750878B2 (en) | 2013-12-11 | 2017-09-05 | Medtronic Minimed, Inc. | Closed-loop control of glucose according to a predicted blood glucose trajectory |
US9750877B2 (en) | 2013-12-11 | 2017-09-05 | Medtronic Minimed, Inc. | Predicted time to assess and/or control a glycemic state |
US10105488B2 (en) | 2013-12-12 | 2018-10-23 | Medtronic Minimed, Inc. | Predictive infusion device operations and related methods and systems |
US9849240B2 (en) | 2013-12-12 | 2017-12-26 | Medtronic Minimed, Inc. | Data modification for predictive operations and devices incorporating same |
US20150164385A1 (en) | 2013-12-16 | 2015-06-18 | Medtronic Minimed, Inc. | Methods and systems for improving the reliability of orthogonally redundant sensors |
US9694132B2 (en) | 2013-12-19 | 2017-07-04 | Medtronic Minimed, Inc. | Insertion device for insertion set |
MX368656B (es) | 2013-12-20 | 2019-10-10 | Hoffmann La Roche | Métodos mejorados para la producción de polipéptidos recombinantes. |
AU2014374361B9 (en) | 2013-12-31 | 2019-07-04 | Abbott Diabetes Care Inc. | Self-powered analyte sensor and devices using the same |
US9861748B2 (en) | 2014-02-06 | 2018-01-09 | Medtronic Minimed, Inc. | User-configurable closed-loop notifications and infusion systems incorporating same |
US9399096B2 (en) | 2014-02-06 | 2016-07-26 | Medtronic Minimed, Inc. | Automatic closed-loop control adjustments and infusion systems incorporating same |
WO2015122964A1 (en) * | 2014-02-11 | 2015-08-20 | Dexcom, Inc. | Packaging system for analyte sensors |
US10034976B2 (en) | 2014-03-24 | 2018-07-31 | Medtronic Minimed, Inc. | Fluid infusion patch pump device with automatic fluid system priming feature |
EP3865063A1 (en) | 2014-03-30 | 2021-08-18 | Abbott Diabetes Care, Inc. | Method and apparatus for determining meal start and peak events in analyte monitoring systems |
US10441717B2 (en) | 2014-04-15 | 2019-10-15 | Insulet Corporation | Monitoring a physiological parameter associated with tissue of a host to confirm delivery of medication |
US10001450B2 (en) | 2014-04-18 | 2018-06-19 | Medtronic Minimed, Inc. | Nonlinear mapping technique for a physiological characteristic sensor |
US10232113B2 (en) | 2014-04-24 | 2019-03-19 | Medtronic Minimed, Inc. | Infusion devices and related methods and systems for regulating insulin on board |
US10275572B2 (en) | 2014-05-01 | 2019-04-30 | Medtronic Minimed, Inc. | Detecting blockage of a reservoir cavity during a seating operation of a fluid infusion device |
US9681828B2 (en) | 2014-05-01 | 2017-06-20 | Medtronic Minimed, Inc. | Physiological characteristic sensors and methods for forming such sensors |
US10274349B2 (en) | 2014-05-19 | 2019-04-30 | Medtronic Minimed, Inc. | Calibration factor adjustments for infusion devices and related methods and systems |
US10152049B2 (en) | 2014-05-19 | 2018-12-11 | Medtronic Minimed, Inc. | Glucose sensor health monitoring and related methods and systems |
US10007765B2 (en) | 2014-05-19 | 2018-06-26 | Medtronic Minimed, Inc. | Adaptive signal processing for infusion devices and related methods and systems |
EP2979623A1 (en) * | 2014-07-28 | 2016-02-03 | Roche Diagnostics GmbH | Medical sensor assembly |
EP2982302B1 (en) | 2014-08-05 | 2018-05-23 | Roche Diabetes Care GmbH | Medical applicator |
NL2013393B1 (en) | 2014-08-30 | 2016-06-21 | Univ Delft Tech | Integrated (bio) detection with micro fluidic micro needles for analytical application. |
US9839753B2 (en) | 2014-09-26 | 2017-12-12 | Medtronic Minimed, Inc. | Systems for managing reservoir chamber pressure |
US9833563B2 (en) | 2014-09-26 | 2017-12-05 | Medtronic Minimed, Inc. | Systems for managing reservoir chamber pressure |
US10279126B2 (en) | 2014-10-07 | 2019-05-07 | Medtronic Minimed, Inc. | Fluid conduit assembly with gas trapping filter in the fluid flow path |
US9833564B2 (en) | 2014-11-25 | 2017-12-05 | Medtronic Minimed, Inc. | Fluid conduit assembly with air venting features |
US10195341B2 (en) | 2014-11-26 | 2019-02-05 | Medtronic Minimed, Inc. | Systems and methods for fluid infusion device with automatic reservoir fill |
US9987420B2 (en) | 2014-11-26 | 2018-06-05 | Medtronic Minimed, Inc. | Systems and methods for fluid infusion device with automatic reservoir fill |
US9943645B2 (en) | 2014-12-04 | 2018-04-17 | Medtronic Minimed, Inc. | Methods for operating mode transitions and related infusion devices and systems |
US9636453B2 (en) | 2014-12-04 | 2017-05-02 | Medtronic Minimed, Inc. | Advance diagnosis of infusion device operating mode viability |
US9937292B2 (en) | 2014-12-09 | 2018-04-10 | Medtronic Minimed, Inc. | Systems for filling a fluid infusion device reservoir |
US10265031B2 (en) | 2014-12-19 | 2019-04-23 | Medtronic Minimed, Inc. | Infusion devices and related methods and systems for automatic alert clearing |
US10307535B2 (en) | 2014-12-19 | 2019-06-04 | Medtronic Minimed, Inc. | Infusion devices and related methods and systems for preemptive alerting |
US10307528B2 (en) | 2015-03-09 | 2019-06-04 | Medtronic Minimed, Inc. | Extensible infusion devices and related methods |
US10449298B2 (en) | 2015-03-26 | 2019-10-22 | Medtronic Minimed, Inc. | Fluid injection devices and related methods |
WO2016183493A1 (en) | 2015-05-14 | 2016-11-17 | Abbott Diabetes Care Inc. | Compact medical device inserters and related systems and methods |
US10213139B2 (en) | 2015-05-14 | 2019-02-26 | Abbott Diabetes Care Inc. | Systems, devices, and methods for assembling an applicator and sensor control device |
US10137243B2 (en) | 2015-05-26 | 2018-11-27 | Medtronic Minimed, Inc. | Infusion devices with distributed motor control and related operating methods |
US9999721B2 (en) | 2015-05-26 | 2018-06-19 | Medtronic Minimed, Inc. | Error handling in infusion devices with distributed motor control and related operating methods |
US10575767B2 (en) | 2015-05-29 | 2020-03-03 | Medtronic Minimed, Inc. | Method for monitoring an analyte, analyte sensor and analyte monitoring apparatus |
US10448885B2 (en) * | 2015-06-12 | 2019-10-22 | Insulet Corporation | Confirmation of delivery of medication to a host |
US9987425B2 (en) | 2015-06-22 | 2018-06-05 | Medtronic Minimed, Inc. | Occlusion detection techniques for a fluid infusion device having a rotary pump mechanism and sensor contact elements |
US9878095B2 (en) | 2015-06-22 | 2018-01-30 | Medtronic Minimed, Inc. | Occlusion detection techniques for a fluid infusion device having a rotary pump mechanism and multiple sensor contact elements |
US9879668B2 (en) | 2015-06-22 | 2018-01-30 | Medtronic Minimed, Inc. | Occlusion detection techniques for a fluid infusion device having a rotary pump mechanism and an optical sensor |
US9993594B2 (en) | 2015-06-22 | 2018-06-12 | Medtronic Minimed, Inc. | Occlusion detection techniques for a fluid infusion device having a rotary pump mechanism and rotor position sensors |
US10010668B2 (en) | 2015-06-22 | 2018-07-03 | Medtronic Minimed, Inc. | Occlusion detection techniques for a fluid infusion device having a rotary pump mechanism and a force sensor |
IL302486A (en) | 2015-06-24 | 2023-06-01 | Hoffmann La Roche | Antibodies against the transnephrine receptor with adapted affinity |
CN108024765B (zh) | 2015-07-10 | 2021-06-11 | 雅培糖尿病护理公司 | 对于生理参数进行动态葡萄糖曲线响应的系统、装置和方法 |
US10201657B2 (en) | 2015-08-21 | 2019-02-12 | Medtronic Minimed, Inc. | Methods for providing sensor site rotation feedback and related infusion devices and systems |
US10293108B2 (en) | 2015-08-21 | 2019-05-21 | Medtronic Minimed, Inc. | Infusion devices and related patient ratio adjustment methods |
US10478557B2 (en) | 2015-08-21 | 2019-11-19 | Medtronic Minimed, Inc. | Personalized parameter modeling methods and related devices and systems |
US10463297B2 (en) | 2015-08-21 | 2019-11-05 | Medtronic Minimed, Inc. | Personalized event detection methods and related devices and systems |
US10664569B2 (en) | 2015-08-21 | 2020-05-26 | Medtronic Minimed, Inc. | Data analytics and generation of recommendations for controlling glycemic outcomes associated with tracked events |
US10117992B2 (en) | 2015-09-29 | 2018-11-06 | Medtronic Minimed, Inc. | Infusion devices and related rescue detection methods |
AR106189A1 (es) | 2015-10-02 | 2017-12-20 | Hoffmann La Roche | ANTICUERPOS BIESPECÍFICOS CONTRA EL A-b HUMANO Y EL RECEPTOR DE TRANSFERRINA HUMANO Y MÉTODOS DE USO |
MX2018003822A (es) | 2015-10-02 | 2018-06-22 | Hoffmann La Roche | Anticuerpos biespecificos contra el cd20 humano y el receptor de transferrina humano y metodos de uso. |
US11501867B2 (en) | 2015-10-19 | 2022-11-15 | Medtronic Minimed, Inc. | Medical devices and related event pattern presentation methods |
US11666702B2 (en) | 2015-10-19 | 2023-06-06 | Medtronic Minimed, Inc. | Medical devices and related event pattern treatment recommendation methods |
US10278732B2 (en) | 2015-10-21 | 2019-05-07 | Dexcom, Inc. | Transcutaneous analyte sensors, applicators therefor, and associated methods |
US10146911B2 (en) | 2015-10-23 | 2018-12-04 | Medtronic Minimed, Inc. | Medical devices and related methods and systems for data transfer |
US10037722B2 (en) | 2015-11-03 | 2018-07-31 | Medtronic Minimed, Inc. | Detecting breakage in a display element |
US10827959B2 (en) | 2015-11-11 | 2020-11-10 | Medtronic Minimed, Inc. | Sensor set |
WO2017091624A1 (en) | 2015-11-24 | 2017-06-01 | Insulet Corporation | Wearable automated medication delivery system |
US10449306B2 (en) | 2015-11-25 | 2019-10-22 | Medtronics Minimed, Inc. | Systems for fluid delivery with wicking membrane |
ES2965609T3 (es) | 2015-12-30 | 2024-04-16 | Dexcom Inc | Sistemas de sensores de analito transcutáneos |
HUE057231T2 (hu) | 2016-01-25 | 2022-04-28 | Hoffmann La Roche | Orvosi eszköz és gyártási eljárás |
US20170290535A1 (en) | 2016-04-08 | 2017-10-12 | Medtronic Minimed, Inc. | Analyte sensor with indicators |
US10765348B2 (en) | 2016-04-08 | 2020-09-08 | Medtronic Minimed, Inc. | Sensor and transmitter product |
US10589038B2 (en) | 2016-04-27 | 2020-03-17 | Medtronic Minimed, Inc. | Set connector systems for venting a fluid reservoir |
US11097051B2 (en) | 2016-11-04 | 2021-08-24 | Medtronic Minimed, Inc. | Methods and apparatus for detecting and reacting to insufficient hypoglycemia response |
US10238030B2 (en) | 2016-12-06 | 2019-03-26 | Medtronic Minimed, Inc. | Wireless medical device with a complementary split ring resonator arrangement for suppression of electromagnetic interference |
US10272201B2 (en) | 2016-12-22 | 2019-04-30 | Medtronic Minimed, Inc. | Insertion site monitoring methods and related infusion devices and systems |
CN115444410A (zh) | 2017-01-23 | 2022-12-09 | 雅培糖尿病护理公司 | 用于插入体内分析物传感器的施加器及组件 |
US10500135B2 (en) | 2017-01-30 | 2019-12-10 | Medtronic Minimed, Inc. | Fluid reservoir and systems for filling a fluid reservoir of a fluid infusion device |
US10532165B2 (en) | 2017-01-30 | 2020-01-14 | Medtronic Minimed, Inc. | Fluid reservoir and systems for filling a fluid reservoir of a fluid infusion device |
US10363365B2 (en) | 2017-02-07 | 2019-07-30 | Medtronic Minimed, Inc. | Infusion devices and related consumable calibration methods |
US10552580B2 (en) | 2017-02-07 | 2020-02-04 | Medtronic Minimed, Inc. | Infusion system consumables and related calibration methods |
US11207463B2 (en) | 2017-02-21 | 2021-12-28 | Medtronic Minimed, Inc. | Apparatuses, systems, and methods for identifying an infusate in a reservoir of an infusion device |
US10646649B2 (en) | 2017-02-21 | 2020-05-12 | Medtronic Minimed, Inc. | Infusion devices and fluid identification apparatuses and methods |
WO2018175489A1 (en) | 2017-03-21 | 2018-09-27 | Abbott Diabetes Care Inc. | Methods, devices and system for providing diabetic condition diagnosis and therapy |
US11027060B2 (en) | 2017-05-08 | 2021-06-08 | Medtronic Minimed, Inc. | Flexible tubing, cannula and insertion needle |
CA3211794A1 (en) | 2017-06-19 | 2018-12-27 | Dexcom, Inc. | Applicators for applying transcutaneous analyte sensors and associated methods of manufacture |
US10863944B2 (en) | 2017-06-23 | 2020-12-15 | Dexcom, Inc. | Transcutaneous analyte sensors, applicators therefor, and associated methods |
US11331022B2 (en) | 2017-10-24 | 2022-05-17 | Dexcom, Inc. | Pre-connected analyte sensors |
US20190120785A1 (en) | 2017-10-24 | 2019-04-25 | Dexcom, Inc. | Pre-connected analyte sensors |
US20190175082A1 (en) | 2017-12-13 | 2019-06-13 | Medtronic Minimed, Inc. | Pseudo-orthogonal redundant glucose sensors, systems, and methods |
KR20240008409A (ko) | 2017-12-13 | 2024-01-18 | 메드트로닉 미니메드 인코포레이티드 | 연속 글루코오스 모니터링 방법 및 시스템 |
US11730403B2 (en) | 2018-02-06 | 2023-08-22 | Arnold Chase | Diversified glucose sensor system |
US11511037B2 (en) | 2018-06-08 | 2022-11-29 | Analog Devices, Inc. | Systems and methods for measuring needle depth |
USD888252S1 (en) | 2018-06-18 | 2020-06-23 | Dexcom, Inc. | Transcutaneous analyte sensor applicator |
USD926325S1 (en) | 2018-06-22 | 2021-07-27 | Dexcom, Inc. | Wearable medical monitoring device |
US11241532B2 (en) | 2018-08-29 | 2022-02-08 | Insulet Corporation | Drug delivery system with sensor having optimized communication and infusion site |
USD1002852S1 (en) | 2019-06-06 | 2023-10-24 | Abbott Diabetes Care Inc. | Analyte sensor device |
USD999913S1 (en) | 2020-12-21 | 2023-09-26 | Abbott Diabetes Care Inc | Analyte sensor inserter |
US11738140B2 (en) * | 2021-01-15 | 2023-08-29 | Medtronic Minimed, Inc. | Insertion device with linkage assembly |
Family Cites Families (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3399674A (en) * | 1965-07-01 | 1968-09-03 | Voys Inc Le | Catheter placement unit |
US3682173A (en) * | 1970-10-16 | 1972-08-08 | Vicra Sterile Inc | Separable catheter insertion device |
US3921631A (en) * | 1972-06-21 | 1975-11-25 | Vicra Sterile Inc | Catheter insertion device and method of catheter introduction |
US3878830A (en) * | 1973-05-31 | 1975-04-22 | Mediscience Technology Corp | Catheter system for blood gas monitoring |
US4141365A (en) * | 1977-02-24 | 1979-02-27 | The Johns Hopkins University | Epidural lead electrode and insertion needle |
US4235234A (en) * | 1978-11-30 | 1980-11-25 | Martin John K Iii | Subcutaneous injection system |
US4573994A (en) * | 1979-04-27 | 1986-03-04 | The Johns Hopkins University | Refillable medication infusion apparatus |
US4685903A (en) * | 1984-01-06 | 1987-08-11 | Pacesetter Infusion, Ltd. | External infusion pump apparatus |
US4678408A (en) * | 1984-01-06 | 1987-07-07 | Pacesetter Infusion, Ltd. | Solenoid drive apparatus for an external infusion pump |
US4562751A (en) * | 1984-01-06 | 1986-01-07 | Nason Clyde K | Solenoid drive apparatus for an external infusion pump |
US4805625A (en) * | 1987-07-08 | 1989-02-21 | Ad-Tech Medical Instrument Corporation | Sphenoidal electrode and insertion method |
US4883053A (en) * | 1987-09-18 | 1989-11-28 | Beth Israel Hospital | Self-supporting angulator device for precise percutaneous insertion of a needle or other object |
US5071408A (en) * | 1988-10-07 | 1991-12-10 | Ahmed Abdul Mateen | Medical valve |
US4953552A (en) * | 1989-04-21 | 1990-09-04 | Demarzo Arthur P | Blood glucose monitoring system |
US5108819A (en) * | 1990-02-14 | 1992-04-28 | Eli Lilly And Company | Thin film electrical component |
US5165407A (en) * | 1990-04-19 | 1992-11-24 | The University Of Kansas | Implantable glucose sensor |
AT397458B (de) * | 1992-09-25 | 1994-04-25 | Avl Verbrennungskraft Messtech | Sensoranordnung |
US5299571A (en) * | 1993-01-22 | 1994-04-05 | Eli Lilly And Company | Apparatus and method for implantation of sensors |
US5390671A (en) * | 1994-03-15 | 1995-02-21 | Minimed Inc. | Transcutaneous sensor insertion set |
US5568806A (en) * | 1995-02-16 | 1996-10-29 | Minimed Inc. | Transcutaneous sensor insertion set |
-
1995
- 1995-02-16 US US08/393,148 patent/US5586553A/en not_active Expired - Lifetime
-
1996
- 1996-02-08 WO PCT/US1996/001672 patent/WO1996025088A1/en active IP Right Grant
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- 1996-02-08 CA CA002186886A patent/CA2186886C/en not_active Expired - Fee Related
- 1996-02-08 JP JP52500996A patent/JP3571727B2/ja not_active Expired - Fee Related
- 1996-02-08 EP EP96905405A patent/EP0748183B1/en not_active Expired - Lifetime
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2009509646A (ja) * | 2005-09-30 | 2009-03-12 | インテュイティ メディカル インコーポレイテッド | 流体サンプル搬送装置および方法 |
JP2016119948A (ja) * | 2014-12-24 | 2016-07-07 | アークレイ株式会社 | センサ挿入方法、分析方法およびセンサ挿入システム |
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CA2186886A1 (en) | 1996-08-22 |
WO1996025088A1 (en) | 1996-08-22 |
DE69630079D1 (de) | 2003-10-30 |
DE69630079T2 (de) | 2004-04-01 |
US5586553A (en) | 1996-12-24 |
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CA2186886C (en) | 2005-07-26 |
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