JP3423355B2 - 自動サンプリング装置 - Google Patents
自動サンプリング装置Info
- Publication number
- JP3423355B2 JP3423355B2 JP12860993A JP12860993A JP3423355B2 JP 3423355 B2 JP3423355 B2 JP 3423355B2 JP 12860993 A JP12860993 A JP 12860993A JP 12860993 A JP12860993 A JP 12860993A JP 3423355 B2 JP3423355 B2 JP 3423355B2
- Authority
- JP
- Japan
- Prior art keywords
- sample
- container
- sampling
- cleaning
- probe
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 238000005070 sampling Methods 0.000 title claims abstract description 103
- 238000004140 cleaning Methods 0.000 claims abstract description 58
- 230000007246 mechanism Effects 0.000 claims abstract description 17
- 238000000034 method Methods 0.000 claims abstract description 15
- 239000000523 sample Substances 0.000 claims description 182
- 239000000126 substance Substances 0.000 claims description 39
- 239000008280 blood Substances 0.000 claims description 28
- 210000004369 blood Anatomy 0.000 claims description 28
- 239000007788 liquid Substances 0.000 claims description 26
- 238000001514 detection method Methods 0.000 claims description 16
- 238000003780 insertion Methods 0.000 claims description 11
- 230000037431 insertion Effects 0.000 claims description 11
- 238000010241 blood sampling Methods 0.000 claims description 5
- 239000012620 biological material Substances 0.000 claims description 4
- 230000006837 decompression Effects 0.000 claims description 3
- 239000000463 material Substances 0.000 abstract description 9
- 239000012530 fluid Substances 0.000 abstract description 4
- 208000027418 Wounds and injury Diseases 0.000 abstract description 3
- 230000006378 damage Effects 0.000 abstract description 3
- 208000014674 injury Diseases 0.000 abstract description 3
- 230000008569 process Effects 0.000 abstract description 2
- 239000000243 solution Substances 0.000 description 12
- 239000006260 foam Substances 0.000 description 11
- 239000002699 waste material Substances 0.000 description 7
- 230000008901 benefit Effects 0.000 description 5
- 239000000203 mixture Substances 0.000 description 5
- 239000003153 chemical reaction reagent Substances 0.000 description 4
- 238000000605 extraction Methods 0.000 description 4
- 238000002347 injection Methods 0.000 description 4
- 239000007924 injection Substances 0.000 description 4
- 238000005406 washing Methods 0.000 description 4
- 238000004458 analytical method Methods 0.000 description 3
- 229910052751 metal Inorganic materials 0.000 description 3
- 239000002184 metal Substances 0.000 description 3
- 239000004926 polymethyl methacrylate Substances 0.000 description 3
- 239000004094 surface-active agent Substances 0.000 description 3
- 239000000725 suspension Substances 0.000 description 3
- 238000012360 testing method Methods 0.000 description 3
- XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical compound [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 description 2
- NIXOWILDQLNWCW-UHFFFAOYSA-N acrylic acid group Chemical group C(C=C)(=O)O NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 description 2
- 230000002457 bidirectional effect Effects 0.000 description 2
- 238000011109 contamination Methods 0.000 description 2
- 238000011161 development Methods 0.000 description 2
- 230000006870 function Effects 0.000 description 2
- 238000005259 measurement Methods 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 230000002572 peristaltic effect Effects 0.000 description 2
- 229920003229 poly(methyl methacrylate) Polymers 0.000 description 2
- 229910052710 silicon Inorganic materials 0.000 description 2
- 239000010703 silicon Substances 0.000 description 2
- JOYRKODLDBILNP-UHFFFAOYSA-N Ethyl urethane Chemical compound CCOC(N)=O JOYRKODLDBILNP-UHFFFAOYSA-N 0.000 description 1
- 229920005439 Perspex® Polymers 0.000 description 1
- 239000004698 Polyethylene Substances 0.000 description 1
- 239000004809 Teflon Substances 0.000 description 1
- 229920006362 Teflon® Polymers 0.000 description 1
- 208000007536 Thrombosis Diseases 0.000 description 1
- RTAQQCXQSZGOHL-UHFFFAOYSA-N Titanium Chemical compound [Ti] RTAQQCXQSZGOHL-UHFFFAOYSA-N 0.000 description 1
- 229920004890 Triton X-100 Polymers 0.000 description 1
- 230000002159 abnormal effect Effects 0.000 description 1
- 239000012190 activator Substances 0.000 description 1
- 238000004164 analytical calibration Methods 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- 230000000903 blocking effect Effects 0.000 description 1
- 239000012482 calibration solution Substances 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 239000000470 constituent Substances 0.000 description 1
- 238000012864 cross contamination Methods 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 238000007598 dipping method Methods 0.000 description 1
- 229920001971 elastomer Polymers 0.000 description 1
- 239000007789 gas Substances 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 229910001026 inconel Inorganic materials 0.000 description 1
- 238000011081 inoculation Methods 0.000 description 1
- HPIGCVXMBGOWTF-UHFFFAOYSA-N isomaltol Natural products CC(=O)C=1OC=CC=1O HPIGCVXMBGOWTF-UHFFFAOYSA-N 0.000 description 1
- 238000012544 monitoring process Methods 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
- 239000003960 organic solvent Substances 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 229920003023 plastic Polymers 0.000 description 1
- -1 polyethylene Polymers 0.000 description 1
- 229920000573 polyethylene Polymers 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 239000012488 sample solution Substances 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- 230000035939 shock Effects 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 230000001360 synchronised effect Effects 0.000 description 1
- 229920002725 thermoplastic elastomer Polymers 0.000 description 1
- 229920001187 thermosetting polymer Polymers 0.000 description 1
- 239000010936 titanium Substances 0.000 description 1
- 229910052719 titanium Inorganic materials 0.000 description 1
- 210000005239 tubule Anatomy 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/04—Preparation or injection of sample to be analysed
- G01N30/16—Injection
- G01N30/18—Injection using a septum or microsyringe
- G01N2030/185—Injection using a septum or microsyringe specially adapted to seal the inlet
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N2035/00178—Special arrangements of analysers
- G01N2035/00237—Handling microquantities of analyte, e.g. microvalves, capillary networks
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N2035/00178—Special arrangements of analysers
- G01N2035/00277—Special precautions to avoid contamination (e.g. enclosures, glove- boxes, sealed sample carriers, disposal of contaminated material)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/04—Preparation or injection of sample to be analysed
- G01N30/24—Automatic injection systems
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1004—Cleaning sample transfer devices
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/11—Automated chemical analysis
- Y10T436/113332—Automated chemical analysis with conveyance of sample along a test line in a container or rack
- Y10T436/114165—Automated chemical analysis with conveyance of sample along a test line in a container or rack with step of insertion or removal from test line
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/11—Automated chemical analysis
- Y10T436/113332—Automated chemical analysis with conveyance of sample along a test line in a container or rack
- Y10T436/114998—Automated chemical analysis with conveyance of sample along a test line in a container or rack with treatment or replacement of aspirator element [e.g., cleaning, etc.]
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/11—Automated chemical analysis
- Y10T436/119163—Automated chemical analysis with aspirator of claimed structure
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
- Y10T436/2575—Volumetric liquid transfer
Landscapes
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- Sampling And Sample Adjustment (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Iron Core Of Rotating Electric Machines (AREA)
- Ultra Sonic Daignosis Equipment (AREA)
- Mechanical Treatment Of Semiconductor (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/891,553 US5372782A (en) | 1992-05-29 | 1992-05-29 | Automated sampling device for medical diagnostic instrument |
| US891553 | 1992-05-29 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPH0694727A JPH0694727A (ja) | 1994-04-08 |
| JP3423355B2 true JP3423355B2 (ja) | 2003-07-07 |
Family
ID=25398402
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP12860993A Expired - Fee Related JP3423355B2 (ja) | 1992-05-29 | 1993-05-31 | 自動サンプリング装置 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US5372782A (enExample) |
| EP (1) | EP0572185B1 (enExample) |
| JP (1) | JP3423355B2 (enExample) |
| AT (1) | ATE183310T1 (enExample) |
| DE (1) | DE69325947T2 (enExample) |
| DK (1) | DK174782B1 (enExample) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5730938A (en) * | 1995-08-09 | 1998-03-24 | Bio-Chem Laboratory Systems, Inc. | Chemistry analyzer |
| US6058934A (en) * | 1995-11-02 | 2000-05-09 | Chiron Diagnostics Corporation | Planar hematocrit sensor incorporating a seven-electrode conductivity measurement cell |
| US5750906A (en) * | 1995-11-02 | 1998-05-12 | Chiron Diagnostics Corporation | Multifunction valve |
| US5762873A (en) * | 1996-02-21 | 1998-06-09 | Biomerieux Vitek, Inc. | Automatic sample testing machine |
| US5697409A (en) * | 1996-02-21 | 1997-12-16 | Biomerieux Vitek, Inc. | Diluting and pipetting stations for sample testing machine |
| US5856194A (en) | 1996-09-19 | 1999-01-05 | Abbott Laboratories | Method for determination of item of interest in a sample |
| US5795784A (en) | 1996-09-19 | 1998-08-18 | Abbott Laboratories | Method of performing a process for determining an item of interest in a sample |
| JP3032159B2 (ja) * | 1996-09-24 | 2000-04-10 | 株式会社日立製作所 | 分析システム |
| SE515423C2 (sv) * | 1998-02-06 | 2001-07-30 | Boule Medical Ab | Förfarande och anordning för spädning av ett blodprov |
| CA2318775C (en) * | 1998-02-10 | 2008-05-06 | Douglas Newberg | Housing for receptacle filling |
| US6074880A (en) * | 1998-08-28 | 2000-06-13 | Transgenomic, Inc. | Sample analyte containing solution fraction collection system, and method of use |
| US7389792B2 (en) * | 1998-12-24 | 2008-06-24 | Nl Technologies, Ltd. | Dip tube valve assembly |
| JP3949379B2 (ja) | 1998-12-24 | 2007-07-25 | エヌエル テクノロジーズ リミテッド | ディップチューブ弁アセンブリ |
| JP2001173820A (ja) * | 1999-12-20 | 2001-06-29 | Fuji Photo Film Co Ltd | バルブ、試料抜き出し装置及び添加装置 |
| JP2002228668A (ja) * | 2001-01-31 | 2002-08-14 | Shimadzu Corp | オートサンプラ |
| AT413002B (de) * | 2002-03-19 | 2005-09-26 | Hoffmann La Roche | Probeneingabevorrichtung für die eingabe medizinischer proben in einen analysator |
| US7396512B2 (en) | 2003-11-04 | 2008-07-08 | Drummond Scientific Company | Automatic precision non-contact open-loop fluid dispensing |
| AT505469B1 (de) * | 2006-05-02 | 2009-03-15 | Hoffmann La Roche | Probeneingabevorrichtung |
| ES2410479T3 (es) * | 2009-09-17 | 2013-07-02 | F.Hoffmann-La Roche Ag | Dispositivo para introducir muestras líquidas (trampas de coágulos) |
| JP5604144B2 (ja) * | 2010-03-23 | 2014-10-08 | 株式会社テクノメデイカ | 検体成分分析装置 |
| CN103521480B (zh) * | 2012-07-06 | 2016-10-26 | 深圳市麦迪聪医疗电子有限公司 | 一种采样针的自动清洗装置的清洗方法 |
| CN102890159B (zh) * | 2012-07-06 | 2014-09-03 | 深圳市麦迪聪医疗电子有限公司 | 一种自动样品识别的采样系统及其方法 |
| CN105004571B (zh) * | 2015-06-30 | 2018-03-30 | 包头瑞鑫稀土金属材料股份有限公司 | 一种稀土熔盐电解槽的精确取样方法 |
| WO2017179157A1 (ja) * | 2016-04-13 | 2017-10-19 | 株式会社島津製作所 | オートサンプラ |
| CN113711050A (zh) * | 2019-05-20 | 2021-11-26 | 深圳迈瑞生物医疗电子股份有限公司 | 样本分析装置及吸液控制方法 |
| MX2024004694A (es) | 2021-10-19 | 2024-05-09 | Siemens Healthcare Diagnostics Inc | Aparato y metodos de insercion de muestras manos libres. |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1988010158A1 (en) | 1987-06-26 | 1988-12-29 | Beckman Instruments, Inc. | Bubble generator |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3989044A (en) * | 1975-08-11 | 1976-11-02 | Warner-Lambert Company | Syringe |
| US4325909A (en) * | 1980-10-24 | 1982-04-20 | Coulter Electronics, Inc. | Fluid transfer apparatus |
| FR2485978A1 (fr) * | 1980-07-04 | 1982-01-08 | Souriau & Cie | Organe de prehension a capteurs optiques et appareil en faisant application |
| DE3144083A1 (de) * | 1980-11-14 | 1982-06-24 | Corning Glass Works, 14830 Corning, N.Y. | Vorrichtung zur entnahme von proben |
| US4454418A (en) * | 1982-04-26 | 1984-06-12 | Walker Clifford G | Integrated optics transducer |
| US4749658A (en) * | 1984-10-19 | 1988-06-07 | Abbott Laboratories | Two-way valve for blood analyzing apparatus |
| US4820497A (en) * | 1986-06-23 | 1989-04-11 | E. I. Du Pont De Nemours And Company | Movable cleaning assembly for an aspirating needle |
| GB8627808D0 (en) * | 1986-11-20 | 1986-12-17 | Cox J A | Sampling liquids from human/animal body |
| AT392362B (de) * | 1987-07-02 | 1991-03-25 | Avl Verbrennungskraft Messtech | Eingabevorrichtung zum einbringen fluessiger oder gasfoermiger medien |
| AT392363B (de) * | 1987-07-06 | 1991-03-25 | Avl Verbrennungskraft Messtech | Eingabevorrichtung zum einbringen fluessiger oder gasfoermiger medien |
| US5012845A (en) * | 1988-08-18 | 1991-05-07 | Dynatech Precision Sampling Corporation | Fluid injector |
| US4962041A (en) * | 1988-10-06 | 1990-10-09 | Medical Automation Specialities, Inc. | Method and apparatus for automatic processing and analyzing of blood serum |
| US5035704A (en) * | 1989-03-07 | 1991-07-30 | Lambert Robert D | Blood sampling mechanism |
| DE4023165A1 (de) * | 1990-07-20 | 1992-01-23 | Kodak Ag | Vorrichtung zum abtasten und zentrieren von behaeltern mit einer fluessigkeit |
-
1992
- 1992-05-29 US US07/891,553 patent/US5372782A/en not_active Expired - Lifetime
-
1993
- 1993-02-25 DK DK199300210A patent/DK174782B1/da not_active IP Right Cessation
- 1993-05-21 EP EP93303964A patent/EP0572185B1/en not_active Expired - Lifetime
- 1993-05-21 DE DE69325947T patent/DE69325947T2/de not_active Expired - Lifetime
- 1993-05-21 AT AT93303964T patent/ATE183310T1/de not_active IP Right Cessation
- 1993-05-31 JP JP12860993A patent/JP3423355B2/ja not_active Expired - Fee Related
- 1993-11-24 US US08/158,107 patent/US5391499A/en not_active Expired - Lifetime
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1988010158A1 (en) | 1987-06-26 | 1988-12-29 | Beckman Instruments, Inc. | Bubble generator |
Also Published As
| Publication number | Publication date |
|---|---|
| DE69325947T2 (de) | 2000-01-20 |
| US5391499A (en) | 1995-02-21 |
| DK21093A (enExample) | 1993-11-30 |
| DE69325947D1 (de) | 1999-09-16 |
| JPH0694727A (ja) | 1994-04-08 |
| EP0572185B1 (en) | 1999-08-11 |
| EP0572185A2 (en) | 1993-12-01 |
| DK174782B1 (da) | 2003-11-03 |
| DK21093D0 (da) | 1993-02-25 |
| US5372782A (en) | 1994-12-13 |
| EP0572185A3 (en) | 1994-08-17 |
| ATE183310T1 (de) | 1999-08-15 |
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