JP3284548B2 - 局所眼用懸濁液剤 - Google Patents

局所眼用懸濁液剤

Info

Publication number
JP3284548B2
JP3284548B2 JP51177991A JP51177991A JP3284548B2 JP 3284548 B2 JP3284548 B2 JP 3284548B2 JP 51177991 A JP51177991 A JP 51177991A JP 51177991 A JP51177991 A JP 51177991A JP 3284548 B2 JP3284548 B2 JP 3284548B2
Authority
JP
Japan
Prior art keywords
suspension
weight
ophthalmic
dry
eye
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP51177991A
Other languages
English (en)
Japanese (ja)
Other versions
JPH05508840A (ja
Inventor
チャンドラスカラン、サントシュ，クマール
リーンツ、マーガレット，ジェイ
バブコック、ジョン，シー
ボーマン、ライル，エム
アーチバルド、ロイ，ディー
ロビンソン、ジョセフ，アール
Original Assignee
インサイト・ビジョン・インコーポレイテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by インサイト・ビジョン・インコーポレイテッド filed Critical インサイト・ビジョン・インコーポレイテッド
Publication of JPH05508840A publication Critical patent/JPH05508840A/ja
Application granted granted Critical
Publication of JP3284548B2 publication Critical patent/JP3284548B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/765—Polymers containing oxygen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/765—Polymers containing oxygen
    • A61K31/78—Polymers containing oxygen of acrylic acid or derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Ophthalmology & Optometry (AREA)
  • Inorganic Chemistry (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Prostheses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP51177991A 1990-07-06 1991-06-25 局所眼用懸濁液剤 Expired - Lifetime JP3284548B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US07/549,093 US5188826A (en) 1988-02-08 1990-07-06 Topical ophthalmic suspensions
US549,093 1990-07-06
PCT/US1991/004350 WO1992000707A1 (en) 1990-07-06 1991-06-25 Topical ophthalmic suspensions

Publications (2)

Publication Number Publication Date
JPH05508840A JPH05508840A (ja) 1993-12-09
JP3284548B2 true JP3284548B2 (ja) 2002-05-20

Family

ID=24191632

Family Applications (1)

Application Number Title Priority Date Filing Date
JP51177991A Expired - Lifetime JP3284548B2 (ja) 1990-07-06 1991-06-25 局所眼用懸濁液剤

Country Status (13)

Country Link
US (1) US5188826A (https=)
EP (1) EP0538313B1 (https=)
JP (1) JP3284548B2 (https=)
AT (1) ATE178476T1 (https=)
AU (1) AU8184991A (https=)
CA (1) CA2086120C (https=)
DE (1) DE69131100T2 (https=)
DK (1) DK0538313T3 (https=)
ES (1) ES2132088T3 (https=)
GR (1) GR3030381T3 (https=)
NZ (1) NZ238850A (https=)
WO (1) WO1992000707A1 (https=)
ZA (1) ZA915220B (https=)

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US5521222A (en) * 1989-09-28 1996-05-28 Alcon Laboratories, Inc. Topical ophthalmic pharmaceutical vehicles
DE4209722C3 (de) * 1992-03-25 1997-06-19 Medproject Pharma Entwicklungs Tropfbares Gel für die Augenheilkunde
US5505953A (en) 1992-05-06 1996-04-09 Alcon Laboratories, Inc. Use of borate-polyol complexes in ophthalmic compositions
TW401300B (en) * 1992-12-25 2000-08-11 Senju Pharma Co Antiallergic composition for ophthalmic or nasal use
DE69411709D1 (de) * 1993-01-21 1998-08-20 Mayo Foundation Mikropartikelschaltvorrichtung
US5340572A (en) * 1993-02-08 1994-08-23 Insite Vision Incorporated Alkaline ophthalmic suspensions
US5654006A (en) * 1993-02-12 1997-08-05 Mayo Foundation For Medical Education And Research Condensed-phase microparticle composition and method
US5820879A (en) * 1993-02-12 1998-10-13 Access Pharmaceuticals, Inc. Method of delivering a lipid-coated condensed-phase microparticle composition
US5753261A (en) * 1993-02-12 1998-05-19 Access Pharmaceuticals, Inc. Lipid-coated condensed-phase microparticle composition
US5474985A (en) * 1993-12-22 1995-12-12 The Regents Of The University Of California Preventing and treating elevated intraocular pressure associated with administered or endogenous steroids using non-steroidal cyclooxygenase inhibitors
CA2184814A1 (en) 1994-03-04 1995-09-14 Allan S. Hoffman Block and graft copolymers and methods relating thereto
US5773021A (en) * 1994-03-14 1998-06-30 Vetoquinol S.A. Bioadhesive ophthalmic insert
FR2717691B1 (fr) * 1994-03-22 1998-02-13 Europhta Laboratoire Nouveaux gels ophtalmiques et leur procédé d'obtention.
US5603929A (en) * 1994-11-16 1997-02-18 Alcon Laboratories, Inc. Preserved ophthalmic drug compositions containing polymeric quaternary ammonium compounds
US5518732A (en) * 1995-02-14 1996-05-21 Chiron Vision, Inc. Bio-erodible ophthalmic shield
US5599535A (en) * 1995-06-07 1997-02-04 Regents Of The University Of California Methods for the cyto-protection of the trabecular meshwork
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US5800807A (en) * 1997-01-29 1998-09-01 Bausch & Lomb Incorporated Ophthalmic compositions including glycerin and propylene glycol
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US6159458A (en) * 1997-11-04 2000-12-12 Insite Vision Sustained release ophthalmic compositions containing water soluble medicaments
US7691829B2 (en) * 1998-03-24 2010-04-06 Petito George D Composition and method for healing tissues
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US7056893B2 (en) 1999-03-31 2006-06-06 Insite Vision, Inc. Topical treatment for prevention of ocular infections
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US7141607B1 (en) 2000-03-10 2006-11-28 Insite Vision Incorporated Methods and compositions for treating and inhibiting retinal neovascularization
HUP0001769A2 (hu) * 2000-05-04 2002-01-28 dr. Kahán Ilona Molnárné Lakrofil készítmény alkalmazása gyógyászati hatóanyag-tartalmú szemcseppekben
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US20040220089A1 (en) * 2001-10-03 2004-11-04 Ellis Edward J. Ophthalmic preparation containing glycoprotein
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US20050143471A1 (en) * 2001-10-22 2005-06-30 Shen Gao Taste masking spill-resistant formulation
US7709026B2 (en) * 2001-10-29 2010-05-04 Columbia Laboratories, Inc. Low concentration of peroxide for treating or preventing vaginal infections
US20030099294A1 (en) * 2001-11-27 2003-05-29 Limin Wang Picture level adaptive frame/field coding for digital video content
US7001615B1 (en) 2001-12-07 2006-02-21 Alcon, Inc. Sustained release ophthalmic, otic and nasal suspension
US6982079B2 (en) * 2002-04-26 2006-01-03 Allergan, Inc. Compositions for treating hyperemia
MXPA05000186A (es) * 2002-07-03 2005-08-17 Pericor Science Inc Composiciones de acido hialuronico y metodos de uso.
US6806364B2 (en) * 2002-07-29 2004-10-19 Ast Products, Inc. Ophthalmic compositions
US6828356B2 (en) * 2002-07-29 2004-12-07 Ast Products, Inc. Preparation of ophthalmic compositions
US7220422B2 (en) * 2003-05-20 2007-05-22 Allergan, Inc. Methods and compositions for treating eye disorders
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US7947295B2 (en) 2003-06-13 2011-05-24 Alcon, Inc. Ophthalmic compositions containing a synergistic combination of two polymers
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US20050137166A1 (en) * 2003-12-19 2005-06-23 Alcon, Inc. Use of cooling agents to relieve mild ocular irritation and enhance comfort
US20050202097A1 (en) * 2004-03-12 2005-09-15 Melbj Holdings, Llc, Florida Lubricant for the ocular surface
US8455016B2 (en) 2004-03-12 2013-06-04 Melbj Holdings, Llc Treatment for meibomian gland dysfunction or obstruction
CN102274172A (zh) * 2004-05-27 2011-12-14 参天制药株式会社 滴眼液
US8338648B2 (en) * 2004-06-12 2012-12-25 Signum Biosciences, Inc. Topical compositions and methods for epithelial-related conditions
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US20060046970A1 (en) * 2004-08-31 2006-03-02 Insite Vision Incorporated Topical otic compositions and methods of topical treatment of prevention of otic infections
US20070208058A1 (en) * 2004-10-25 2007-09-06 Bryant Roy W Stable Pharmaceutical Compositions and Methods of Making and Using Same
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TW200722109A (en) * 2005-03-31 2007-06-16 Bausch & Lomb Polysaccharide and polyol composition for treating dry eye and related methods of manufacture and methods of use
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WO2007120818A2 (en) * 2006-04-12 2007-10-25 Massachusetts Institute Of Technology Compositions and methods for inhibiting adhesions
JP2009535342A (ja) 2006-04-26 2009-10-01 アーシエックス， インコーポレイテッド 眼瞼腫脹の予防および処置のための組成物
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US8778999B2 (en) 2009-03-05 2014-07-15 Insite Vision Incorporated Non-steroidal anti-inflammatory ophthalmic compositions
US8569273B2 (en) * 2009-03-17 2013-10-29 Aciex Therapeutics, Inc. Ophthalmic formulations of cetirizine and methods of use
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Also Published As

Publication number Publication date
ES2132088T3 (es) 1999-08-16
EP0538313B1 (en) 1999-04-07
NZ238850A (en) 1992-11-25
WO1992000707A1 (en) 1992-01-23
CA2086120C (en) 2001-09-04
DE69131100D1 (de) 1999-05-12
US5188826A (en) 1993-02-23
EP0538313A1 (en) 1993-04-28
GR3030381T3 (en) 1999-09-30
ATE178476T1 (de) 1999-04-15
DK0538313T3 (da) 1999-10-18
DE69131100T2 (de) 1999-08-12
JPH05508840A (ja) 1993-12-09
CA2086120A1 (en) 1992-01-07
ZA915220B (en) 1992-08-26
AU8184991A (en) 1992-02-04
EP0538313A4 (https=) 1994-04-13

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