JP2969177B2 - 分析方法 - Google Patents

分析方法

Info

Publication number
JP2969177B2
JP2969177B2 JP1508299A JP50829989A JP2969177B2 JP 2969177 B2 JP2969177 B2 JP 2969177B2 JP 1508299 A JP1508299 A JP 1508299A JP 50829989 A JP50829989 A JP 50829989A JP 2969177 B2 JP2969177 B2 JP 2969177B2
Authority
JP
Japan
Prior art keywords
optical structure
binding partner
ligand
specific binding
light
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP1508299A
Other languages
English (en)
Japanese (ja)
Other versions
JPH03502604A (ja
Inventor
ワーシングトン アトリッジ，ジョン
イアン アレクサンダー シャンクス
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
APURAIDO RISAACHI SHISUTEMUZU AA ERU ESU HOORUDEINGU NV
Original Assignee
APURAIDO RISAACHI SHISUTEMUZU AA ERU ESU HOORUDEINGU NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by APURAIDO RISAACHI SHISUTEMUZU AA ERU ESU HOORUDEINGU NV filed Critical APURAIDO RISAACHI SHISUTEMUZU AA ERU ESU HOORUDEINGU NV
Publication of JPH03502604A publication Critical patent/JPH03502604A/ja
Application granted granted Critical
Publication of JP2969177B2 publication Critical patent/JP2969177B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/648—Specially adapted constructive features of fluorimeters using evanescent coupling or surface plasmon coupling for the excitation of fluorescence
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/55—Specular reflectivity
    • G01N21/552—Attenuated total reflection
    • G01N21/553—Attenuated total reflection and using surface plasmons
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Examining Or Testing Airtightness (AREA)
JP1508299A 1988-07-25 1989-07-25 分析方法 Expired - Fee Related JP2969177B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB888817710A GB8817710D0 (en) 1988-07-25 1988-07-25 Method of assay
GB8817710.0 1988-07-25

Publications (2)

Publication Number Publication Date
JPH03502604A JPH03502604A (ja) 1991-06-13
JP2969177B2 true JP2969177B2 (ja) 1999-11-02

Family

ID=10641075

Family Applications (1)

Application Number Title Priority Date Filing Date
JP1508299A Expired - Fee Related JP2969177B2 (ja) 1988-07-25 1989-07-25 分析方法

Country Status (11)

Country Link
EP (2) EP0353937A1 (de)
JP (1) JP2969177B2 (de)
AU (1) AU638938B2 (de)
CA (1) CA1339005C (de)
DE (1) DE68914134T2 (de)
ES (1) ES2050277T3 (de)
GB (1) GB8817710D0 (de)
IL (1) IL91105A0 (de)
NO (1) NO177407C (de)
WO (1) WO1990001166A1 (de)
ZA (1) ZA895648B (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL9001052A (nl) * 1990-05-02 1991-12-02 Tno Werkwijze voor het bepalen van een specifiek ligand in een vloeibaar monster met behulp van een evanescent veld, alsook een daarvoor geschikt onderdeel van de benodigde meetinrichting.
DE4024476C1 (de) * 1990-08-02 1992-02-27 Boehringer Mannheim Gmbh, 6800 Mannheim, De
GB9102646D0 (en) * 1991-02-07 1991-03-27 Fisons Plc Analytical device
DE69110032T2 (de) * 1991-06-08 1995-12-21 Hewlett Packard Gmbh Verfahren und Gerät zur Feststellung und/oder Konzentrationsbestimmung von Biomolekülen.
EP0575132A1 (de) * 1992-06-17 1993-12-22 Hewlett-Packard Company Optische Messvorrichtung
SE9301270D0 (sv) * 1993-04-19 1993-04-17 Biosensor
US5919712A (en) 1993-05-18 1999-07-06 University Of Utah Research Foundation Apparatus and methods for multi-analyte homogeneous fluoro-immunoassays
US5677196A (en) * 1993-05-18 1997-10-14 University Of Utah Research Foundation Apparatus and methods for multi-analyte homogeneous fluoro-immunoassays
US5395587A (en) * 1993-07-06 1995-03-07 Smithkline Beecham Corporation Surface plasmon resonance detector having collector for eluted ligate
US5814565A (en) * 1995-02-23 1998-09-29 University Of Utah Research Foundation Integrated optic waveguide immunosensor
US6611634B2 (en) 1996-03-19 2003-08-26 University Of Utah Research Foundation Lens and associatable flow cell
US5776785A (en) * 1996-12-30 1998-07-07 Diagnostic Products Corporation Method and apparatus for immunoassay using fluorescent induced surface plasma emission
DE19715483A1 (de) 1997-04-14 1998-10-15 Boehringer Mannheim Gmbh Methode zur gleichzeitigen Bestimmung von biomolekularen Wechselwirkungen mittels Plasmonenresonanz undFluoreszenzdetektion
US6222619B1 (en) 1997-09-18 2001-04-24 University Of Utah Research Foundation Diagnostic device and method
DE102004027957A1 (de) * 2004-06-08 2005-12-29 Carl Zeiss Jena Gmbh Verfahren und Anordnung zur Untersuchung der Wechselwirkung von Biomolekülen
US20070177150A1 (en) * 2006-01-27 2007-08-02 Gruhlke Russell W Surface plasmon resonance biosensor using coupled surface plasmons to decrease width of reflectivity dip
EP1818668A1 (de) * 2006-02-09 2007-08-15 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Weitreichende Oberflächenplasmonenfluoreszenzspektroskopie für Bioaffinitätsuntersuchungen
JP2008102117A (ja) 2006-09-21 2008-05-01 Fujifilm Corp 表面プラズモン増強蛍光センサおよび蛍光検出方法
US20170082612A1 (en) 2015-09-17 2017-03-23 Gerhard Maale Sensor device for biosensing and other applications

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4649280A (en) 1985-05-10 1987-03-10 The University Of Rochester Method and system for the enhancement of fluorescence
GB2185308B (en) 1986-01-10 1989-10-25 Stc Plc Optical sensor device

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58501481A (ja) * 1981-09-18 1983-09-01 プルーテック　リミティド 光学的導波体による溶液中検査物の測定方法および装置
GB8415018D0 (en) * 1984-06-13 1984-07-18 Unilever Plc Chemical test procedures
EP0170375B1 (de) * 1984-06-13 1990-05-16 Unilever Plc Vorrichtungen zur Verwendung in chemischen Analyseverfahren
GB8509491D0 (en) * 1985-04-12 1985-05-15 Plessey Co Plc Optic waveguide biosensors
GB8705650D0 (en) * 1987-03-10 1987-04-15 Pa Consulting Services Assay technique
NL8700851A (nl) * 1987-04-10 1988-11-01 Tno Werkwijze en inrichting voor het detecteren van zeer lage concentraties van een in een meetmedium aanwezige chemische component onder toepassing van oppervlakte-plasmonresonantie en elektrochemisch gestimuleerde adsorptie.
CA1321488C (en) * 1987-08-22 1993-08-24 Martin Francis Finlan Biological sensors
NL8701998A (nl) * 1987-08-26 1989-03-16 Univ Leiden Werkwijze voor het door hydrogenolyse ontleden van chemische afvalstoffen, in het bijzonder organische halogeenverbindingen.
GB8813307D0 (en) * 1988-06-06 1988-07-13 Amersham Int Plc Biological sensors

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4649280A (en) 1985-05-10 1987-03-10 The University Of Rochester Method and system for the enhancement of fluorescence
GB2185308B (en) 1986-01-10 1989-10-25 Stc Plc Optical sensor device

Also Published As

Publication number Publication date
GB8817710D0 (en) 1988-09-01
EP0382832A1 (de) 1990-08-22
NO177407B (no) 1995-05-29
EP0382832B1 (de) 1994-03-23
ZA895648B (en) 1990-06-27
DE68914134D1 (de) 1994-04-28
CA1339005C (en) 1997-03-25
DE68914134T2 (de) 1994-08-11
IL91105A0 (en) 1990-03-19
ES2050277T3 (es) 1994-05-16
NO901349D0 (no) 1990-03-23
AU4043389A (en) 1990-02-19
AU638938B2 (en) 1993-07-15
NO177407C (no) 1995-09-06
JPH03502604A (ja) 1991-06-13
NO901349L (no) 1990-05-23
EP0353937A1 (de) 1990-02-07
WO1990001166A1 (en) 1990-02-08

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