JP2838030B2 - 損傷した脊柱椎間板を交換するための脊柱椎間板プロテーゼ - Google Patents

損傷した脊柱椎間板を交換するための脊柱椎間板プロテーゼ

Info

Publication number
JP2838030B2
JP2838030B2 JP6015466A JP1546694A JP2838030B2 JP 2838030 B2 JP2838030 B2 JP 2838030B2 JP 6015466 A JP6015466 A JP 6015466A JP 1546694 A JP1546694 A JP 1546694A JP 2838030 B2 JP2838030 B2 JP 2838030B2
Authority
JP
Japan
Prior art keywords
spinal disc
plate
disc prosthesis
core
plates
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP6015466A
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English (en)
Other versions
JPH06285099A (ja
Inventor
リチャード・エイ・ナバロー
カール・アール・マクミリン
カリ・ビー・ジマーズ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
DePuy Spine LLC
Original Assignee
Acromed Corp
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Publication date
Application filed by Acromed Corp filed Critical Acromed Corp
Publication of JPH06285099A publication Critical patent/JPH06285099A/ja
Application granted granted Critical
Publication of JP2838030B2 publication Critical patent/JP2838030B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/44Joints for the spine, e.g. vertebrae, spinal discs
    • A61F2/442Intervertebral or spinal discs, e.g. resilient
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/30767Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/30767Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
    • A61F2/30771Special external or bone-contacting surface, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes or grooves
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/3094Designing or manufacturing processes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2002/30001Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30003Material related properties of the prosthesis or of a coating on the prosthesis
    • A61F2002/3006Properties of materials and coating materials
    • A61F2002/30069Properties of materials and coating materials elastomeric
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2002/30001Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30108Shapes
    • A61F2002/3011Cross-sections or two-dimensional shapes
    • A61F2002/30112Rounded shapes, e.g. with rounded corners
    • A61F2002/30125Rounded shapes, e.g. with rounded corners elliptical or oval
    • A61F2002/30128Rounded shapes, e.g. with rounded corners elliptical or oval concentric ellipses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2002/30001Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30108Shapes
    • A61F2002/3011Cross-sections or two-dimensional shapes
    • A61F2002/30112Rounded shapes, e.g. with rounded corners
    • A61F2002/30133Rounded shapes, e.g. with rounded corners kidney-shaped or bean-shaped
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2002/30001Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30108Shapes
    • A61F2002/30199Three-dimensional shapes
    • A61F2002/30242Three-dimensional shapes spherical
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2002/30001Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30316The prosthesis having different structural features at different locations within the same prosthesis; Connections between prosthetic parts; Special structural features of bone or joint prostheses not otherwise provided for
    • A61F2002/30535Special structural features of bone or joint prostheses not otherwise provided for
    • A61F2002/30563Special structural features of bone or joint prostheses not otherwise provided for having elastic means or damping means, different from springs, e.g. including an elastomeric core or shock absorbers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/30767Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
    • A61F2002/30769Special external or bone-contacting surface, e.g. coating for improving bone ingrowth madreporic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/30767Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
    • A61F2/30771Special external or bone-contacting surface, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes or grooves
    • A61F2002/30841Sharp anchoring protrusions for impaction into the bone, e.g. sharp pins, spikes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/30767Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
    • A61F2/30771Special external or bone-contacting surface, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes or grooves
    • A61F2002/30878Special external or bone-contacting surface, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes or grooves with non-sharp protrusions, for instance contacting the bone for anchoring, e.g. keels, pegs, pins, posts, shanks, stems, struts
    • A61F2002/30879Ribs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/30767Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
    • A61F2/30771Special external or bone-contacting surface, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes or grooves
    • A61F2002/30878Special external or bone-contacting surface, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes or grooves with non-sharp protrusions, for instance contacting the bone for anchoring, e.g. keels, pegs, pins, posts, shanks, stems, struts
    • A61F2002/30891Plurality of protrusions
    • A61F2002/30892Plurality of protrusions parallel
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/3094Designing or manufacturing processes
    • A61F2002/30968Sintering
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2230/00Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2230/0002Two-dimensional shapes, e.g. cross-sections
    • A61F2230/0004Rounded shapes, e.g. with rounded corners
    • A61F2230/0008Rounded shapes, e.g. with rounded corners elliptical or oval
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
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    • A61F2230/0002Two-dimensional shapes, e.g. cross-sections
    • A61F2230/0004Rounded shapes, e.g. with rounded corners
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2230/00Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2230/0063Three-dimensional shapes
    • A61F2230/0071Three-dimensional shapes spherical
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00389The prosthesis being coated or covered with a particular material
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00389The prosthesis being coated or covered with a particular material
    • A61F2310/00395Coating or prosthesis-covering structure made of metals or of alloys
    • A61F2310/00407Coating made of titanium or of Ti-based alloys

Description

【発明の詳細な説明】
【0001】
【産業上の利用分野】本発明は、損傷を受け又は変質し
た脊柱椎間板を交換するための人工脊柱椎間板プロテー
ゼ(補綴具)に関する。
【0002】
【従来の技術】公知の脊柱椎間板プロテーゼは、米国特
許第3,867,728号に開示されている。
【0003】
【発明が解決しようとする課題】該米国特許第3,867,72
8号には、一形態にて、凹状の外面を呈するように成形
した単一のエラストマー片を備える脊柱椎間板プロテー
ゼが開示されている。このエラストマーは、二つの外側
カバー要素の間に介装され且つこれらの外側カバー要素
に接着されている。該凹状の外周面は、そのカバー要素
の一方から外方まで伸長する。この脊柱髄椎間板プロテ
ーゼに曲げモーメントが加わったとき、エラストマーコ
アの凹状の外周面は、一側部に沿って延伸する。このエ
ラストマーコアが一側部ら沿って延伸すること起因して
脊柱椎間板に生ずる応力は、エラストマーコアと二つの
カバー要素との間の境界部分で最大となる。その結果、
これらのカバー要素がエラストマーコアから分離する可
能性がある。
【0004】米国特許第5,071,437号には、平坦な上方
剛性板と、平坦な下方剛性板と、これらの板の間に介装
され且つ該板に接着された平坦なエラストマーコアと、
を備える脊柱椎間板プロテーゼが開示されている。これ
らの板をエラストマーコアに固着するため、該エラスト
マーコアに隣接して多孔性被覆が板の上に付与されてい
る。板の一方とエラストマーコアとの間に亀裂が生じた
場合、この亀裂は、板とエラストマーコアとの間の境界
を横断して広がり、板をエラストマーコアから分離させ
る傾向を生ずる。
【0005】
【課題を解決するための手段】本発明は、損傷を受けた
脊柱椎間板を交換するための新規且つ改良に係る脊柱椎
間板プロテーゼを提供するものである。本発明の脊柱椎
間板プロテーゼは、直立剛性板と、下方剛性板と、これ
らの板の間に介装され且つこれら板に接着されたエラス
トマーコアと、を備えている。該エラストマーコアは、
上方板から伸長する上方部分を有する。該エラストマー
コアの上方部分は、上方板に対して略垂直に伸長する外
周面を有する。該エラストマーコアの下方部分は、下方
板から伸長し、又、該下方部分は、この下方板に対して
略垂直に伸長する外周面を有する。コアの中間部分は、
上方部分と下方部分との間を伸長し、また、凹状の外周
面を有する。脊柱椎間板プロテーゼに曲げモーメント及
び/又は並進力が付与されたとき、凹状面の一側部の延
伸に起因する応力は、直線状の周縁側部を有するコアと
比べて、板とコアとの交点にて小さくなる。凹状の外周
面は、コアが上方板及び下方板に交差する箇所ではな
く、コア本体内で上方部分及び下方部分の外周面に交差
する。このため、上方板及び下方板は、エラストマーコ
アから分離し難くなる。
【0006】上方板及び下方板の各々は、エラストマー
コア内に伸長し(埋め込まれ)且つ該コアに接着された
少なくとも一つのリブを備えている。これら板の各々
は、板の外周面と略同一形状のコア内に伸長する複数の
同心状リブを備えている。このように、板の上のリブ
は、板の外周面に対して同心状となる。また、リブは、
板及びコアが分離する傾向を軽減する。例えば、板の一
方とコアとの間に亀裂が生じた場合、その亀裂は、板と
コアとの境界部分を横断して広がるならば、リブに達し
たとき、その方向を変更しなければならない。これは、
板とコアとが分離する可能性を更に小さくする。
【0007】
【実施例】本発明の上記及びその他の特徴は、当業者が
添付図面に関する以下の詳細な説明を読むことによっ
て、一層明らかになるであろう。
【0008】脊柱椎間板プロテーゼ5(図1)は、人間
の脊柱の上方及び下方椎骨6、7の間に配置されてい
る。該脊柱椎間板プロテーゼ5は、上方剛性板12と、
下方剛性板14と、これら二枚の剛性板12、14の間
に介装され且つこれらの板に接着されたエラストマーコ
ア16と、を備えている(図2及び図3参照)。上方板
12は、エラストマーコア16に接着された面22(図
3)を備える一方、下方板14は、エラストマーコア1
6に接着された面24を備えている。板12の面22
は、面24が位置する第二の面に対して約3°の角度で
伸長する第一の面内に位置する。このため、脊柱椎間板
エラストマー5及びエラストマーコア16は、楔状の形
状を有する。しかし、エラストマーコア16は、均一な
厚さとし、これにより、剛性板12、14が互いに平行
となるようにすることが可能である。
【0009】エラストマーコア16は、上方板12から
伸長する上方部分30を備えている。該上方部分30の
厚さは、板12、14の各々の厚さよりも著しく厚い。
上方部分30は、上方板12に対して略垂直に伸長する
外周面32を有する。また、エラストマーコア16は、
板12、14の各々の厚さよりも著しく厚く、上方部分
30の厚さに等しい下方部分34を備えている。エラス
トマーコア16の下方部分34は、下方板14に対して
略垂直に伸長する外周面36を有する。エラストマーコ
ア16の中間部分38は、上方部分30と下方部分34
との間を伸長する。該中間部分38は、凹状の外周面を
有する。
【0010】エラストマーコア16の厚さ全体のうち、
上方部分30は、33%を僅かに下廻り約31%であり、ま
た、下方部分34は、33%を僅かに下廻り約31%、中間
部分38は、33%を僅かに上廻り約38%である。また、
エラストマーコア16は、楔状の形状であるため、下方
部分34及び上方部分30も楔状の形状である。即ち、
これら部分は、脊柱椎間板5の片側からその反対側に伸
長するに伴い厚さが変化する。中間部分38は、略均一
な厚さである。該中間部分が均一な厚さで、エラストマ
ーコア16が楔状の形状であるため、中間部分は、脊柱
椎間板5の前方側より脊柱椎間板5の後方側にて、コア
の厚さに占める比率が大きい。
【0011】板12、14は、同一であり、従って、そ
の一方の板12にのみについて説明する。該板12は、
湾曲した凸状側部46(図4)及び反対側の凹状側部4
8を有する、平面図で見てインゲン豆の形状であること
が望ましい。図4に示した形態は、人間の自然の脊柱椎
間板の形状に略適合し得るようにしてある。平面図で見
たときのエラストマーコア16の寸法は、平面図で見た
板12、14の寸法に等しい。このため、剛性板12、
14及びエラストマーコア16は、互いに完全に重なり
合い、剛性板12、14は、エラストマーコア16を越
えて伸長せず、また、エラストマーコア16が剛性板1
2、14を越えて伸長することはない。
【0012】板12は、複数の同心状インゲン豆の形状
のリブ50、51、52(図5乃至図7)を備えてい
る。これらの板12、14の各々は、三つのリブ50、
51、52を備えることが望ましい。また、これらのリ
ブ50、51、52は、板12の外周面に対して同心状
である。
【0013】該リブ50は、板の外周面付近で板12か
ら伸長する。リブ52は、板の中心に対して相対的に接
近するように板12から伸長する一方、リブ51は、リ
ブ50、52の間の領域内で板から伸長する。これらの
リブ50、51の間の距離は、リブ51、52の間の距
離に等しい。これらのリブ50、51、52は、エラス
トマーコア16内まで伸長し、該エラストマーコア16
に接着されて、板12、14を該コア16に固着させ易
くする。板12の外周のリブ54(図5)がコア16か
ら伸長して離れ、リブ50、51、52が伸長する側と
反対側の板12の側部に凹所56を形成する。板12
は、該板の外周に沿って面取り部分60を備えている。
該エラストマーコア16は、該面取り部分60を覆う
(図6に図示)。
【0014】上方板12及び下方板14の双方は、その
対向面に、複数の円錐状突起62を備えており、これら
の突起は、離間され且つ板から垂直外方に伸長する。こ
れら突起62は、対向する椎骨6、7内の着座部、又は
凹所内に嵌まり得るようにしてある。突起62は、脊柱
椎間板5を椎骨6、7に対して位置決めし、その位置を
維持する機能を果たす。
【0015】凹所56は、多孔性被覆66を受け入れ
る。また、板の内面22には、多孔性被覆68、70、
72、74が被覆される。多孔性被覆68は、リブ50
と板12の外周との間に位置する。多孔性被覆70は、
リブ50、51の間に位置する一方、多孔性被覆72
は、リブ51、52の間に位置する。多孔性被覆74
は、リブ52内に位置し且つリブ52により囲繞されて
いる。これらのリブ50、51、52は、多孔性被覆に
より被覆されていない。
【0016】多孔性被覆66を受け入れる凹所56を形
成するリブ54は、多孔性被覆66が板から伸長する距
離を僅かに上廻る距離だけ板12から外方に伸長する。
図5及び図6参照。リブ50、51、52は、多孔性被
覆68乃至74が板から伸長する距離を僅かに上廻る距
離だけ板12から伸長する。このため、リブ50、5
1、52は、エラストマーコア16内に相当な距離を伸
長し、板12、14をエラストマーコアに固着する。
【0017】多孔性被覆66乃至74は、小さい球状粒
子層を備えている。該球状粒子は、商業的に純粋なチタ
ニウムにて形成することが望ましいが、生体に適合可能
な任意の適当な材料で形成してもよい。該球状粒子の寸
法は、その球状粒子が25メッシュ米国ふるいを通過せ
ず、また、その全ての球状粒子が40メッシュ米国ふるい
を通過し得るような寸法とする。これら粒子は、蒸着、
プラズマジェット溶射、焼結又はその他の任意の適当な
技術で板に付与することが出来る。被覆66乃至74
は、板12、14に強固に固着され、通常の摩擦力で除
去することは出来ない。多孔性被覆66は、該被覆66
が存在しない場合よりも組織の内部成長を促進し、骨が
板12、14により強固に取り付くことを可能にする。
被覆68乃至74は、エラストマーコア16の材料と相
互にからみ合い、板12、14とエラストマーコア16
とを強固に結合させる。
【0018】本発明の好適な実施例において、該エラス
トマーコアは、共に、ダウ・コーニング(Dow Cornin
g)によって製造された、重量比70%のH.P.100 4099シ
リコンエラストマーと、重量比30%のH.P.100 4106シリ
コンエラストマーと、から成る複合物で形成される。AS
TM 2240-86試験法で試験したとき、H.P.100 4099エラス
トマーの硬さは、52乃至60の範囲にあり、H.P.100 4106
エラストマーの硬さは、65乃至75の範囲にある。ASTM D
412−87試験法で試験したとき、H.P.100 4099エラスト
マーの極限引張り強さは、1,100 psi以上、H.P.100 410
6エラストマーの極限引張り強さは、1,000 psi以上であ
り、シリコンエラストマーの各々の極限延びは、500%
以上である。D624-86試験法で試験したとき、シリコン
エラストマーの各々は、250 psi以上の引き裂き抵抗を
有する。エラストマーコア16は、H.P.100 4099及びH.
P.100 4106の複合物から成るものとして開示されている
が、このエラストマーコア16は、自然の椎間板の特徴
を提供する任意のエラストマー材料で形成することが出
来る。
【0019】板12、14は、重量比で約90%のチタニ
ウム、重量比で約6%のアルミニウム、及び重量比で約
4% のバナジウムを有するチタニウム−バナジウム−
アルミニウム合金のような、生体に適合可能な金属で形
成することが望ましい。板12、14は、チタニウム−
バナジウム−アルミニウム合金で形成されるものとして
開示されているが、これらの板は、複合プラスチック材
料等のような任意の適当な生体に適合可能な材料で形成
することが出来るが、これらにのみ限定されるものでは
ない。
【0020】板12、14は、金属ブロックから加工す
る。しかし、板12、14は、例えば、鋳造のようなそ
の他の方法で製造してもよい。多孔性被覆66−74を
形成する球状粒子をこれらの板の上に載せ、板を粒子と
共に高温の加熱炉中に入れ、粒子を板に固着することに
より、板12、14に焼結することが望ましい。
【0021】プロテーゼ5を製造するためには、被覆6
6−74を所定位置に有する板12、14をメチルエチ
ルケトン、又は同様の試薬浴中で約25分間、洗浄する。
次に、板をアルカリ洗浄溶液で洗浄し、蒸留水で水洗い
をする。次に、これらの板を硫酸酸洗い溶液のような酸
溶液に浸漬し、蒸留水で水洗いする。次に、例えば、硝
酸フッ化水素酸溶液でこれらの板を腐食させ、板から酸
化被覆物を除去する。次に、板を蒸留水で水洗いし、コ
ア16に接着される板の全面に塩化ヘプタン/メチレン
中のDC−1107の約5%溶液のようなプライマーを塗布す
る。このプライマーは、 約2時間以内で塗布する。DC−
1107は、ダウ・コーニングが製造している。次に、板は
金型内に入れ、エラストマー材料を金型中に流動させ、
リブ50、51、52及び被覆68、70、72、74
に接着させる。次に、そのエラストマーを硬化させる。
【0022】
【発明の効果】脊柱椎間板5に曲げモーメント及び/又
は並進力が加えられると、凹状面40の一側部の延伸に
起因する応力は、直線状の側部を有する周縁コアと比べ
て、コアと板との交差部分で小さくなる。このため、こ
れらの板がエラストマーコアから分離する傾向が軽減さ
れる。
【0023】また、板12、14の一方とコア16との
間に亀裂が生じた場合、その亀裂は、板とコアとの間の
境界を横断して広がる場合、リブ50、51、52の一
つに達したとき、その方向を変更する。亀裂が広がり続
ける場合と比べて、リブが存在するとき、亀裂がかかる
方向変化する可能性は少ない。このため、板12、14
がコア16から分離する可能性は最小となる。
【0024】当業者は、本発明の上記の説明からその改
良、変更及び改造例が案出されよう。当業者の能力の範
囲のかかる改良、変更及び改造例は、特許請求の範囲に
包含されるべきものである。
【図面の簡単な説明】
【図1】本発明による人工脊柱椎間板が嵌め込まれた間
の脊柱の立面図である。
【図2】図1の人工脊柱椎間板の斜視図である。
【図3】図2の脊柱椎間板の立面図である。
【図4】図3の脊柱椎間板の一部である板の平面図であ
る。
【図5】図4の線5−5に沿った図4の板の断面図であ
る。
【図6】図5の板の一部分の拡大断面図である。
【図7】図4の板の底面図である。
【符号の説明】
5 脊柱椎間板プロテーゼ 6、7 椎骨 12 上方剛性板 14 下方剛性
板 16 エラストマーコア 22、24 面 30 上方部分 32 上方部分
の外周面 34 下方部分 36 下方部分
の外周面 38 コアの中間部分 46 板の凸状
側部 48 板の凹状側部 56 板の凹所
側部 50、51、52、54 リブ 60 面取り部分 62 突起 66、68、70、72、74 多孔性被覆
───────────────────────────────────────────────────── フロントページの続き (72)発明者 カール・アール・マクミリン アメリカ合衆国オハイオ州44141,ブレ ックスヴィル,ウォーブラーズ・ロース ト 6099 (72)発明者 カリ・ビー・ジマーズ アメリカ合衆国オハイオ州44266,ラベ ンナ,ウエスト・リデル・アベニュー 889 (56)参考文献 特開 平4−303444(JP,A) 特開 平3−275055(JP,A) 特開 平2−215461(JP,A) 特開 平5−317407(JP,A) (58)調査した分野(Int.Cl.6,DB名) A61F 2/44

Claims (15)

    (57)【特許請求の範囲】
  1. 【請求項1】 損傷した脊柱椎間板を交換するための脊
    柱椎間板プロテーゼにして、上方剛性板と、 下方剛性板と、 前記板の間に介装されかつ該板に固着されたエラストマ
    ーコアであって、前記上方板から伸長する上方部分であ
    って、前記上方板に対して略垂直に伸長する外周面を有
    する上方部分と、前記下方板から伸長する下方部分であ
    って、前記下方板に対して略垂直に伸長する外周面を有
    する下方部分と、前記上方及び下方部分の間を伸長する
    中間部分であって、凹状の外周面を有する中間部分と、
    を有するエラストマーコアと、を備えることを特徴とす
    る脊柱椎間板プロテーゼ。
  2. 【請求項2】 請求項1に記載の脊柱椎間板プロテーゼ
    にして、前記コアの前記上方部分及び下方部分が前記板
    の各々の厚さを実質的に上廻る厚さを有することを特徴
    とする脊柱椎間板プロテーゼ。
  3. 【請求項3】 請求項1に記載の脊柱椎間板プロテーゼ
    にして、前記上方板が第一の面内に位置する下側面を有
    し、前記下方板が第二の面内に位置する上側面を有し、
    前記第一の面が前記第二の面に対して角度を成して伸長
    することを特徴とする脊柱椎間板プロテーゼ。
  4. 【請求項4】 請求項3に記載の脊柱椎間板プロテーゼ
    にして、前記第一の面が前記第二の面に対して約3°の
    角度で伸長することを特徴とする脊柱椎間板プロテー
    ゼ。
  5. 【請求項5】 請求項1に記載の脊柱椎間板プロテーゼ
    にして、前記板の各々が前記エラストマーコアに接着さ
    れかつ該コア内に伸長する少なくとも一つのリブを備え
    ることを特徴とする脊柱椎間板プロテーゼ。
  6. 【請求項6】 請求項5に記載の脊柱椎間板プロテーゼ
    にして、前記リブが前記板の外周面と略同一の形状を有
    することを特徴とする脊柱椎間板プロテーゼ。
  7. 【請求項7】 請求項5に記載の脊柱椎間板プロテーゼ
    にして、前記板の各々が前記エラストマーコア内に伸長
    する複数のリブを備えることを特徴とする脊柱椎間板プ
    ロテーゼ。
  8. 【請求項8】 損傷した脊柱椎間板を交換するための脊
    柱椎間板プロテーゼにして、上方剛性板と、 下方剛性板と、 前記板の間に介装されかつ該板に固着されたエラストマ
    ーコアとを備え、 前記上方板及び下方板の各々が、該板が前記コアから分
    離するのに抵抗し得るように、前記エラストマーコアに
    接着されかつ該コア内に伸長する少なくとも一つのリブ
    を備えることを特徴とする脊柱椎間板プロテーゼ。
  9. 【請求項9】 請求項8に記載の脊柱椎間板プロテーゼ
    にして、前記リブが前記板の外周面と略同一の形状を有
    することを特徴とする脊柱椎間板プロテーゼ。
  10. 【請求項10】 請求項9に記載の脊柱椎間板プロテー
    ゼにして、前記板及び前記コアがインゲン豆状の形状で
    あることを特徴とする脊柱椎間板プロテーゼ。
  11. 【請求項11】 請求項8に記載の脊柱椎間板プロテー
    ゼにして、前記板の各々が前記エラストマーコアに接着
    され且つ該コア内に伸長する複数のリブを備えることを
    特徴とする脊柱椎間板プロテーゼ。
  12. 【請求項12】 請求項11に記載の脊柱椎間板プロテ
    ーゼにして、前記複数のリブが同心状であり、前記板の
    外周面と略同一の形状を有することを特徴とする脊柱椎
    間板プロテーゼ。
  13. 【請求項13】 請求項8に記載の脊柱椎間板プロテー
    ゼにして、前記板の各々が前記エラストマーコアから外
    方に伸長するリブを備え、該外方に伸長するリブが前記
    板に凹所及び前記凹所内に配置される多孔性の粒子被覆
    を形成していることを特徴とする脊柱椎間板プロテー
    ゼ。
  14. 【請求項14】 請求項8に記載の脊柱椎間板プロテー
    ゼにして、前記エラストマーコアが、前記上方板から伸
    長する上方部分であって、前記上方板に対して略垂直に
    伸長する外周面を有する上方部分と、前記下方板から伸
    長する下方部分であって、前記下方板に対して略垂直に
    伸長する外周面を有する下方部分と、前記第一及び第二
    の部分の間を伸長する中間部分であって、凹状の外周面
    を有する中間部分と、を備えることを特徴とする脊柱椎
    間板プロテーゼ。
  15. 【請求項15】 請求項14に記載の脊柱椎間板プロテ
    ーゼにして、前記上方部分が前記コアの厚さの約31%、
    前記下方部分が前記コアの厚さの約31%、前記中間部分
    が前記コアの厚さの約38%であることを特徴とする脊
    柱椎間板プロテーゼ。
JP6015466A 1993-02-09 1994-02-09 損傷した脊柱椎間板を交換するための脊柱椎間板プロテーゼ Expired - Lifetime JP2838030B2 (ja)

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AU663638B2 (en) 1995-10-12
ATE205069T1 (de) 2001-09-15
DE69428143D1 (de) 2001-10-11
JPH06285099A (ja) 1994-10-11
ES2161725T3 (es) 2001-12-16
EP0610837A1 (en) 1994-08-17
DE69428143T2 (de) 2002-05-29
AU5500294A (en) 1994-08-18
EP0610837B1 (en) 2001-09-05
US5534030A (en) 1996-07-09

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