JP2724379B2 - Core for pearl culture and method for producing the same - Google Patents
Core for pearl culture and method for producing the sameInfo
- Publication number
- JP2724379B2 JP2724379B2 JP1020746A JP2074689A JP2724379B2 JP 2724379 B2 JP2724379 B2 JP 2724379B2 JP 1020746 A JP1020746 A JP 1020746A JP 2074689 A JP2074689 A JP 2074689A JP 2724379 B2 JP2724379 B2 JP 2724379B2
- Authority
- JP
- Japan
- Prior art keywords
- nucleus
- pearl
- chemical derivative
- collagen
- gelatin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A40/00—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
- Y02A40/80—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in fisheries management
- Y02A40/81—Aquaculture, e.g. of fish
Landscapes
- Farming Of Fish And Shellfish (AREA)
Description
【発明の詳細な説明】 （産業上の利用分野） 本発明は、真珠養殖に於ける母貝に挿入する核及びそ
の製造方法に関し、該核に改良処理を施すことによっ
て、従来の真珠養殖用の核を用いて養殖した場合に比較
し、品質の高い真珠を高収率で得るようにした技術に関
する。Description: TECHNICAL FIELD The present invention relates to a nucleus to be inserted into a mother pearl in pearl culture and a method for producing the nucleus. The present invention relates to a technique for obtaining high-quality pearls at a high yield as compared with the case where the pearls are cultured using nuclei.
（従来の技術及び解決すべき課題） 養殖真珠は、外套膜の切片と真珠の核となる物質をア
コヤ貝、シロチョウ貝、クロチョウ貝、マベ、アワビ、
イケチョウ貝、カラス貝、ドブ貝、ヒレイケチョウ貝、
カワシンジュ貝等の母貝の中に人為的に挿入して生産さ
れる。現在、養殖真珠の核となる物質として真珠層と成
分がほぼ同じドブ貝等の二枚貝の貝殻が主に用いられて
いる。この貝殻を研磨し表面を平滑にした後挿入する。
核を挿入する挿核手術は主として４月〜７月に行なわれ
ているが、貝の生理状態、挿核手術および海況諸条件、
気象状況等により、脱核、貝の死亡等養殖真珠の収率及
び真珠の品質等が大きく影響される。また、現在核とし
て主に用いられている二枚貝の貝殻等では商品価値の高
い真珠のできる割合が低く、真珠養殖業者の労の割合に
は収率が低いといわれている。(Prior art and problems to be solved) Cultured pearls are composed of pearl oysters, white clams, black mussels, mabe, abalone,
Ginkgo mussels, crow clams, gibbon clams, flatfish clams,
It is produced by artificially inserting it into mother shells such as kawashinju shellfish. At present, shells of bivalves such as mussels having almost the same components as nacres are mainly used as the core material of cultured pearls. The shell is polished to smooth the surface and then inserted.
Nucleus insertion surgery to insert a nucleus is mainly performed from April to July.
Depending on weather conditions, the yield of cultured pearls such as enucleation and death of shellfish and the quality of pearls are greatly affected. In addition, it is said that the yield of pearls with high commercial value is low in the bivalve shells and the like that are currently mainly used as cores, and the yield is low compared with the labor of pearl farmers.
本発明は、高品質の真珠を収率よく得るための真珠養
殖用の核及びその製造方法を提供することを目的とす
る。An object of the present invention is to provide a pearl culture nucleus for obtaining high-quality pearls with good yield and a method for producing the nucleus.
（課題を解決するための手段） 本発明者等は、商品価値の高い真珠ができる割合を高
めるため、人為的に操作できる核に注目し、研究の結
果、真珠の真珠層を作る真珠袋上皮細胞にとってその形
成状態および核との初期接合が極めて重要であり、核の
表面に形成状態の良い真珠袋上皮細胞を作らしめ、且つ
核との初期接合を良くするコラーゲンの化学的誘導体及
びゼラチンの化学的誘導体からなる群より選ばれた１種
又は２種以上の化合物の被膜を形成させることにより上
記の問題点を解決しうることを知見し、また抗生物質を
含有させることにより母貝の死亡率を低減させ得ること
を知見し、本発明を完成した。(Means for Solving the Problems) The present inventors have focused on artificially manipulable nuclei in order to increase the ratio of pearls having high commercial value, and as a result of research, have found pearl bag epithelium that forms pearl layers. It is extremely important for cells to form their nuclei and their initial junction with the nucleus is very important. It was found that the above problems could be solved by forming a film of one or more compounds selected from the group consisting of chemical derivatives, and death of mother mussels was caused by containing antibiotics. The inventors have found that the rate can be reduced, and completed the present invention.
すなわち本発明は、核表面に、コラーゲンの化学的誘
導体及びゼラチンの化学的誘導体からなる群より選ばれ
た１種又は２種以上の化合物に抗生物質を含有させた被
膜を厚さ0.005μｍ以上好ましくは0.01〜100μｍで形成
させることにより、形成状態の良い真珠袋上皮細胞を作
らしめ且つ核との初期接合を良好にするものである。核
の表面に前記の物質の被膜を形成させることにより、挿
入された外套膜切片は速やかに真珠袋を形成し、有機質
層や稜柱層など非真珠層分泌物の分泌を極力抑制し、正
常な真珠層を核に向けて分泌しはじめ、また抗生物質の
抗菌作用により、脱核、貝の死亡等が少なくなり、良質
の真珠を形成するようになる。That is, in the present invention, a film containing an antibiotic in one or more compounds selected from the group consisting of a chemical derivative of collagen and a chemical derivative of gelatin on a nuclear surface is preferably 0.005 μm or more in thickness. Is to form a pearl bag epithelial cell with a good formation state and to form a good initial bond with the nucleus by forming it at 0.01 to 100 μm. By forming a coating of the substance on the surface of the nucleus, the inserted mantle section quickly forms a pearl pouch, suppresses the secretion of non-pearl layer secretions such as the organic layer and the trabecular layer as much as possible, The nacre starts to be secreted toward the nucleus, and the antibacterial action of the antibiotic reduces enucleation and death of the shellfish, thereby forming a high-quality pearl.
上記の改良された養殖真珠の核は、次のようにして製
造される。すなわち、養殖真珠の核をコラーゲンの化学
的誘導体及びゼラチンの化学的誘導体からなる群より選
ばれた１種又は２種以上の化合物の0.01〜１％水溶液に
抗生物質を添加した溶液でコーティング処理し、核表面
に厚さ0.005μｍ以上の被膜を形成させる。The core of the above-mentioned improved cultured pearl is manufactured as follows. That is, the cultured pearl nucleus is coated with a solution obtained by adding an antibiotic to a 0.01 to 1% aqueous solution of one or more compounds selected from the group consisting of a chemical derivative of collagen and a chemical derivative of gelatin. A film having a thickness of 0.005 μm or more is formed on the core surface.
本発明で用いるコラーゲンの化学的誘導体及びゼラチ
ンの化学的誘導体は均一な水溶液を形成しうるものであ
ることが必要であり、以下に述べる各種のものが用いら
れる。コラーゲンの化学的誘導体の原料となるコラーゲ
ンは、牛、ラット、マウス等の哺乳動物、更には鳥類、
魚類等各種の動物から酸抽出した酸可溶性コラーゲン、
又はこれら動物の不溶性コラーゲンをペプシン等の酵素
で処理して可溶化したアテロコラーゲン、又はアルカリ
処理により可溶化したコラーゲンである。コラーゲンの
化学的誘導体はこれらのコラーゲンを化学的に修飾し
て、例えばサクシニル化などのアシル化、又はメチル化
して製造する。またゼラチンの化学的誘導体の原料とな
るゼラチンは、一般試薬グレードのもの又は上記コラー
ゲンを熱変性して製造したものなどである。ゼラチンの
化学的誘導体もコラーゲンと同様にゼラチンを化学的に
修飾して、例えばサクシニル化などのアシル化、又はメ
チル化して製造する。コラーゲン及びゼラチンを化学的
誘導体にして用いることにより、真珠袋の形成と核との
初期接合をより良くし良質な真珠層に改良することが出
来る。The chemical derivative of collagen and the chemical derivative of gelatin used in the present invention must be capable of forming a uniform aqueous solution, and various types described below are used. Collagen as a raw material of chemical derivatives of collagen is a mammal such as cattle, rats, mice, and even birds,
Acid-soluble collagen extracted from various animals such as fish,
Or atelocollagen obtained by treating insoluble collagen of these animals with an enzyme such as pepsin, or collagen solubilized by alkali treatment. Chemical derivatives of collagen are produced by chemically modifying these collagens, for example, by acylation such as succinylation, or methylation. The gelatin used as a raw material of the chemical derivative of gelatin may be of a general reagent grade or produced by thermally denaturing the above collagen. Chemical derivatives of gelatin are also produced by chemically modifying gelatin in the same manner as collagen, for example, by acylation such as succinylation, or methylation. By using collagen and gelatin as chemical derivatives, it is possible to improve the formation of pearl pouches and the initial bonding with the nucleus, thereby improving the quality of nacre.
本発明では、コラーゲンの化学的誘導体及びゼラチン
の化学的誘導体はそれぞれ水に溶解する条件で溶解して
用い、その濃度は0.01〜１％の範囲である。またコラー
ゲンの化学的誘導体及びゼラチンの化学的誘導体は単独
で用いても、混合して用いてもよい。そして、本発明に
おいて、核表面を上記の化合物の水溶液でコーティング
処理するに当り、該水溶液に抗生物質を添加する。コラ
ーゲンの化学的誘導体又はゼラチンの化学的誘導体に基
づく上記の作用と抗生物質の抗菌作用が相まって、脱核
率、母貝の死亡率を極めて低減させることができる。こ
の場合、コラーゲンの化学的誘導体又はゼラチンの化学
的誘導体は抗生物質の担体（キャリヤー）としての作用
をなし、抗生物質を徐放するので抗生物質の抗菌作用を
長期間持続することができる。In the present invention, the chemical derivative of collagen and the chemical derivative of gelatin are used by dissolving them under the condition of dissolving in water, respectively, and the concentration is in the range of 0.01 to 1%. Further, the chemical derivative of collagen and the chemical derivative of gelatin may be used alone or in combination. In the present invention, an antibiotic is added to the aqueous solution when the surface of the nucleus is coated with an aqueous solution of the above compound. The above-described action based on the chemical derivative of collagen or the chemical derivative of gelatin, combined with the antibacterial action of antibiotics, can greatly reduce the enucleation rate and the mortality rate of mother mussels. In this case, the chemical derivative of collagen or the chemical derivative of gelatin acts as a carrier for the antibiotic, and releases the antibiotic gradually, so that the antibacterial action of the antibiotic can be maintained for a long period of time.
抗生物質としては一般に水産業で用いられている例え
ばテトラサイクリン、ストレプトマイシン、カナマイシ
ンなど水産庁が定める水産用抗生物質等が用いられ、添
加量はその薬効により異なるが、コラーゲンの化学的誘
導体又はゼラチンの化学的誘導体に対し0.1〜20倍量が
好ましい。薬剤が多くなりすぎた場合、滑らかな被膜を
作ることが困難になる。As antibiotics, fishery antibiotics generally used by the fisheries industry, for example, tetracycline, streptomycin, kanamycin and the like specified by the Fisheries Agency are used. The amount is preferably 0.1 to 20 times the amount of the derivative. If there is too much drug, it will be difficult to create a smooth coating.
コーティング処理は市販のコーティング装置（例え
ば、フロイント産業株式会社製の商品名ハイコーター）
でおこなえる。コーティング処理の条件は特に限定され
ないが、核の表面にコラーゲンの化学的誘導体、ゼラチ
ンの化学的誘導体あるいはこれらの混合物の被膜が0.00
5μｍ以上の厚さに形成されるように行なう。コーティ
ング処理した核は母貝に挿入する。The coating process is a commercially available coating device (for example, a high-coater (trade name, manufactured by Freund Corporation))
Can be done with The conditions for the coating treatment are not particularly limited, but a coating of a chemical derivative of collagen, a chemical derivative of gelatin, or a mixture of these on the surface of the nucleus may be used.
This is performed so that the thickness is 5 μm or more. The coated nucleus is inserted into the mother mussel.
コーティング処理した核の表面の被膜に架橋処理を施
すことにより、本発明の効果を高めることができる。架
橋処理は、例えば紫外線照射（例、波長253.7nm）する
か、加熱処理するか、0.01〜１％のグルタールアルデヒ
ド溶液（PH4〜10）で処理するか、0.01〜５％のポリエ
ポキシ化合物溶液（PH4〜10）で処理するか、0.01〜１
％のヘキサメチレンジイソシアネート溶液で処理する。
これら架橋処理した核は、紫外線照射で架橋処理したも
のと加熱によるもの以外は、充分に水洗いし、風乾して
から母貝に挿入する。The effect of the present invention can be enhanced by subjecting the coating on the surface of the coated nucleus to a crosslinking treatment. The crosslinking treatment may be, for example, ultraviolet irradiation (eg, 253.7 nm wavelength), heat treatment, treatment with a 0.01 to 1% glutaraldehyde solution (PH4 to 10), or a 0.01 to 5% polyepoxy compound solution. (PH4 ~ 10) or 0.01 ~ 1
% Hexamethylene diisocyanate solution.
These crosslinked nuclei are thoroughly washed with water, air-dried, and then inserted into the mother mussel, except for those which have been crosslinked by ultraviolet irradiation and those which have been heated.
本発明において、コーティング処理する核としては従
来主に用いられていた二枚貝の貝殻のほかに、さんご、
大理石、セラミック、ガラス、合成樹脂、炭酸カルシウ
ムの成型物等が使用でき、これらを球状、偏平状又は棒
状に加工して用いる。また、本発明は、核を貝殻内面に
直接接着剤で貼り付けるか、あるいは貝殻外面より穿孔
して外側から核を母貝内部に入れるかし、貝の外套膜そ
のものが真珠層分泌器官となる半形真珠又はスリークオ
ーター真珠の養殖用の核にも適用できる。これらの核の
形は半球状、球状、ドロップ（液滴）状、ハート型状な
ど種々の形である。核の材質としては上記の各種のもの
が用いられる。In the present invention, as a core to be coated, in addition to the shells of bivalves which have been mainly used in the past, coral,
A marble, ceramic, glass, synthetic resin, calcium carbonate molded product or the like can be used, and these are processed into a spherical, flat, or rod shape for use. Also, the present invention provides that the nucleus is directly adhered to the inner surface of the shell with an adhesive, or the nucleus is inserted into the mother shell from the outside by piercing from the outer surface of the shell, and the shell of the shell itself becomes a nacre secretory organ. The present invention can also be applied to a culture nucleus of a half-shaped pearl or a three-quarter pearl. These nuclei have various shapes such as a hemisphere, a sphere, a drop (droplet), and a heart. As the material of the nucleus, the various materials described above are used.
実施例１ アテロコラーゲンを既知の方法でサクシニル化処理し
サクシニル化アテロコラーゲンとした。サクシニル化ア
テロコラーゲン5gに５の水を加え、更に1Nに調整した
希塩酸を4ml加えサクシニル化アテロコラーゲン水溶液
（サクシニル化アテロコラーゲン濃度0.1％、pH3）を作
った。この水溶液にシクシニル化コラーゲンに対し等重
量になるようにテトラサイクリンを混合した。Example 1 Atelocollagen was succinylated by a known method to obtain succinylated atelocollagen. Water of 5 was added to 5 g of succinylated atelocollagen, and 4 ml of diluted hydrochloric acid adjusted to 1N was further added to prepare a succinylated atelocollagen aqueous solution (succinylated atelocollagen concentration 0.1%, pH 3). This aqueous solution was mixed with tetracycline so as to have the same weight as the succinylated collagen.
この混合溶液をフロイント産業（株）製のコーティン
グ装置（ハイコーター:HCT−MINI）を用いて、下記の条
件にてコーティングし、風乾した。核にはドブ貝を直径
6mmの球に加工したビーズを用いた。This mixed solution was coated under the following conditions using a coating device (Hicoater: HCT-MINI) manufactured by Freund Corporation and air-dried. Dwarf shell diameter in the nucleus
Beads processed into 6 mm spheres were used.
核の仕込み量 0.6kg スプレー空気圧 1kg/cm2 スプレー空気量 20／分 スプレーガン HM型１個 スプレーガンノズル口径 0.7φmm スプレーガンエアキャップ 1.2φmm 液温 11〜15℃ コーティングパン径 200φmm パン回転数 20r.p.m. 所要時間330分、使用液量300mlであった。この場合の
コラーゲンの被膜の厚さは平均約15μｍであった。この
コーティングされた核を母貝に挿入し養殖した。母貝の
１年後の死亡率はコントロールが約25％に対し、約10％
となり、歩留、良質珠出現率も向上した。Core loading 0.6kg Spray air pressure 1kg / cm 2 Spray air volume 20 / min Spray gun HM type 1 piece Spray gun nozzle diameter 0.7φmm Spray gun air cap 1.2φmm Liquid temperature 11-15 ℃ Coating pan diameter 200φmm Pan rotation speed 20r. pm The required time was 330 minutes and the amount of liquid used was 300 ml. The thickness of the collagen coating in this case was about 15 μm on average. This coated nucleus was inserted into a mother mussel and cultured. The mortality rate of the mother mussel one year later is about 10%, compared to about 25% for the control
As a result, the yield and the appearance rate of high quality pearls also improved.
アテロコラーゲンのサクシニル化物の代わりにゼラチ
ンのサクシニル化物を用いた場合も同様な効果を得た。Similar effects were obtained when succinylated gelatin was used instead of succinylated atelocollagen.
（発明の効果） 本発明では、養殖真珠を生産する母貝に挿入する核の
表面に、コラーゲンの化学的誘導体及びゼラチンの化学
的誘導体からなる群より選ばれた化合物又はこれらの２
種以上の混合物に抗生物質を含有させた被膜を設けたた
め、核を母貝に挿核手術で挿入しても核による母貝の器
官の損傷が最小限に押えられ、且つ損傷からの回復も早
く、しかも抗生物質の抗菌作用が相まって、脱核率、母
貝の死亡率を一層低減させることができ、更にこのコラ
ーゲンの化学的誘導愛体及びゼラチンの化学的誘導体は
抗生物質を徐々に放出する作用も持っているので抗生物
質の抗菌作用を長期間持続することができる。また、上
記被覆の存在により形成状態の良い真珠袋上皮細胞が作
られ、また核との初期接合を良い。そのため、本発明に
よると、良質の商品価値の高い養殖真珠を高収率で生産
することができる。(Effect of the Invention) In the present invention, a compound selected from the group consisting of a chemical derivative of collagen and a chemical derivative of gelatin, or a compound thereof, is formed on the surface of a nucleus inserted into a mother pearl producing cultured pearls.
Because a mixture containing more than one species is provided with a coating containing an antibiotic, even if the nucleus is inserted into the mother shell by intubation surgery, damage to the organ of the mother shell due to the nucleus is minimized, and recovery from damage is also achieved. The antibacterial effect of antibiotics is fast, and the enucleation rate and the mortality rate of mother shellfish can be further reduced, and the chemically induced form of collagen and the chemical derivative of gelatin gradually release antibiotics. The antibacterial effect of the antibiotic can be maintained for a long period of time. In addition, the pearl bag epithelial cells in a well-formed state are produced by the presence of the above-mentioned coating, and the initial bonding with the nucleus is good. Therefore, according to the present invention, cultured pearls of good quality and high commercial value can be produced in high yield.
また、コラーゲンの化学的誘導体及びゼラチンの化学
的誘導体からなる群より選ばれた１種又は２種以上の化
合物は、水溶液にして用いるのでコーティング処理が容
易であり、又均一に被膜を形成できる。In addition, one or more compounds selected from the group consisting of a chemical derivative of collagen and a chemical derivative of gelatin are used in an aqueous solution, so that coating treatment is easy and a uniform film can be formed.
───────────────────────────────────────────────────── フロントページの続き (72)発明者 平 敏夫 東京都目黒区中根２―11―21 株式会社 高研研究所内 ──────────────────────────────────────────────────の Continuing on the front page (72) Inventor Toshio Taira 2-11-21 Nakane, Meguro-ku, Tokyo Inside the Koken Research Laboratory Co., Ltd.
Claims (5)
ゼラチンの化学的誘導体からなる群より選ばれた１種又
は２種以上の化合物の被膜を厚さ0.005μｍ以上で有
し、且つ上記被膜が抗生物質を含有することを特徴とす
る真珠養殖用の核。1. A coating of one or more compounds selected from the group consisting of a chemical derivative of collagen and a chemical derivative of gelatin on the surface of a nucleus with a thickness of 0.005 μm or more. Pearl culture nuclei, characterized in that they contain antibiotics.
化学的誘導体からなる群より選ばれた１種又は２種以上
の化合物の被膜が架橋処理された被膜である請求項第１
項記載の真珠養殖用の核。2. A coating film of one or more compounds selected from the group consisting of a chemical derivative of collagen and a chemical derivative of gelatin is a coating film subjected to a cross-linking treatment.
A pearl culture nucleus according to the above item.
養殖用の核である請求項第１項又は第２項記載の真珠養
殖用の核。3. The pearl culturing nucleus according to claim 1, wherein the nucleus is a nucleus for culturing a half-shaped pearl or a three-quarter pearl.
導体及びゼラチンの化学的誘導体からなる群より選ばれ
た１種又は２種以上の化合物の0.01〜１％水溶液に抗生
物質を添加した溶液でコーティング処理し、核表面に厚
さ0.005μｍ以上の被膜を形成させたことを特徴とする
真珠養殖用の核の製造方法。4. A pearl culture nucleus is prepared by adding an antibiotic to a 0.01-1% aqueous solution of one or more compounds selected from the group consisting of a chemical derivative of collagen and a chemical derivative of gelatin. A method for producing a nucleus for pearl culture, comprising coating a solution with a solution to form a film having a thickness of 0.005 μm or more on the surface of the nucleus.
すことを特徴とする請求項第４項記載の真珠養殖用の核
の製造方法。5. The method for producing a pearl culture nucleus according to claim 4, wherein the coating formed on the nucleus surface is subjected to a crosslinking treatment.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP1020746A JP2724379B2 (en) | 1989-02-01 | 1989-02-01 | Core for pearl culture and method for producing the same |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP1020746A JP2724379B2 (en) | 1989-02-01 | 1989-02-01 | Core for pearl culture and method for producing the same |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP1318970A Division JPH0387128A (en) | 1989-12-11 | 1989-12-11 | Nucleus for pearl culture and its production |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPH02203724A JPH02203724A (en) | 1990-08-13 |
| JP2724379B2 true JP2724379B2 (en) | 1998-03-09 |
Family
ID=12035756
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP1020746A Expired - Fee Related JP2724379B2 (en) | 1989-02-01 | 1989-02-01 | Core for pearl culture and method for producing the same |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP2724379B2 (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU3406800A (en) * | 2000-05-12 | 2001-11-22 | Koken Co., Ltd. | A coated nucleus for a cultured pearl |
| FR2964014B1 (en) * | 2010-08-31 | 2013-04-05 | Ifremer | NUCLEUS COATED WITH A FILMOGENEOUS COATING WITH ANTIBACTERIAL AND CICATRISANT PROPERTIES AND METHOD OF OBTAINING THE SAME |
| AU2019358933B2 (en) | 2018-10-12 | 2021-08-19 | Fujifilm Corporation | Pearl culture material, nucleus insertion method, and pearl culture material composition |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5931636A (en) * | 1982-08-11 | 1984-02-20 | 辻尾パ−ル工業株式会社 | Production of breeded pearl |
| JPH01148135A (en) * | 1987-12-07 | 1989-06-09 | Matsushita Pearl Kk | Nucleus for pearl cultivation and pearl cultivation |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5318398Y2 (en) * | 1973-11-20 | 1978-05-17 |
-
1989
- 1989-02-01 JP JP1020746A patent/JP2724379B2/en not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5931636A (en) * | 1982-08-11 | 1984-02-20 | 辻尾パ−ル工業株式会社 | Production of breeded pearl |
| JPH01148135A (en) * | 1987-12-07 | 1989-06-09 | Matsushita Pearl Kk | Nucleus for pearl cultivation and pearl cultivation |
Also Published As
| Publication number | Publication date |
|---|---|
| JPH02203724A (en) | 1990-08-13 |
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