CN104381179B - A kind of method reducing nucleated pearl flaw - Google Patents
A kind of method reducing nucleated pearl flaw Download PDFInfo
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- CN104381179B CN104381179B CN201410726688.1A CN201410726688A CN104381179B CN 104381179 B CN104381179 B CN 104381179B CN 201410726688 A CN201410726688 A CN 201410726688A CN 104381179 B CN104381179 B CN 104381179B
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- margarita
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A40/00—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
- Y02A40/80—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in fisheries management
- Y02A40/81—Aquaculture, e.g. of fish
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Abstract
The present invention relates to a kind of method reducing nucleated pearl flaw, belong to pearl cultivation technology field.The technical scheme is that, medicinal liquid, containing the medicinal liquid of Drug sustained-release microspheres, is entered in the through hole bored on pearl core by the way of immersion by preparation, by pearl renucleation Margarita body, in medicinal liquid is admitted to Margarita body simultaneously；Antibiotics in medicinal liquid can directly play antibacterial and anti-inflammation functions, medicament slow-release microsphere sustained release drug plays anti-inflammation and the effect promoting pearl sac to be formed, effectively prevention Zhi He shellfish wound tissue and the inflammatory reaction of mantle piece, reduce Margarita flaw and the ratio of flaw Margarita, improve pearl quality.
Description
Technical field
The present invention relates to a kind of method reducing nucleated pearl flaw, belong to pearl cultivation technology field.
Background technology
Margarita is a kind of organic gemstone secreted by Margarita, all natural perals of Margarita in ancient times.Natural peral quantity little, shape difference few, individual, along with the progress of science and technology, carried out artificial cultivation nucleated pearl modern age, and had formed industry.Now, though Margarita quantity is greatly increased, but the Margarita of artificial cultivation is not the most perfect, and wherein most exists flaw.Flaw ratio is the key factor affecting nucleated pearl quality and price, such as, have about 80% to have flaw in the Margarita utilizing pteria martensii to cultivate, about its price only 10,000 yuan/kilogram.The kind of Margarita flaw mainly has black speck, tail, projection etc., and research shows: plant core shellfish due to wound tissue's inflammatory reaction of being caused of operation be the major reason forming flaw Margarita.In recent years, it is developed pearl core and external carbon dosage small pieces drug treating technology, to reduce wound tissue's inflammatory reaction, to improve pearl quality, but there is the medication amount entered in Margarita body and be difficult to control, and enter the medicine in Margarita body by the problem of tachymetabolism.The healing of pearly shellfish wound and wound tissue needs the time of a couple of days, and present pearl core and external carbon dosage small pieces drug treating technology are difficult to the most persistently play antibacterial and anti-inflammation functions, retrieves pertinent literature, also there are no the report about similar techniques.
Summary of the invention
It is an object of the invention to provide a kind of method reducing nucleated pearl flaw, this method preferably overcomes existing drug treating pearl core and the deficiency of mantle piece method, solve medicine can not be efficiently entering in Margarita body, and the problem that action time is short in Margarita body.
The present invention adopts the technical scheme that: the preparation medicinal liquid containing Drug sustained-release microspheres；The pearl core of boring is put into the liquid, agitation, make in medicinal liquid access aperture；By in pearl renucleation Margarita body, being stored in pearl core boring herb liquid and constantly discharge medicine, the long period plays anti-inflammation and the effect promoting pearl sac to be formed, and reduces the formation of Margarita flaw, specifically comprises the following steps that
(1) pearl core pre-treatment: bore the through hole of 1～2 diameter 0.5～0.8mm with puncher on pearl core, then cleaned up by the pearl core of boring, be placed in clean fresh water after scalding, dries, standby；
(2) preparating liquid: sodium carboxymethyl cellulose (CMC-Na), antibacterials are made into aqueous solution, then add antibacterials sustained-release micro-spheres, stirring in the solution configured, makes antibacterials sustained-release micro-spheres be evenly distributed, prepare medicinal liquid；
(3) pearl core processes: put in medicinal liquid configure by pearl core punch, sterilizing, dry, and stirs, and allows full medicinal liquid in the through hole on pearl core；
(4) plant core to be administered: in the pearl renucleation Margarita body that will process with nucleus sending device, the medicine in pearl core through hole is admitted in Margarita body simultaneously；
(5) sheet is sent: traditionally implant external carbon dosage small pieces, and make it be close to pearl core；
(6) grow cultured pearls in sea area: the pearly shellfish completing to plant core operation is placed in sea area cultivation 6～12 months.
Described pearl core is tradition pearl core, the pearl core i.e. made by mussel or sea water Concha Tridacna squamosa shell.
In described medicinal liquid, CMC-Na's act as being formed the hydrosol, the viscosity of increase medicinal liquid, beneficially medicament slow-release microsphere being uniformly distributed in medicinal liquid.
The mass concentration of described sodium carboxymethyl cellulose (CMC-Na) is 1～2%.
Described antibacterials are one or more of water miscible cephalo-type, quinolones and beta-lactam antibiotic.
The mass concentration of described antibacterials is 1～2%.
One or more that antibacterials sustained-release micro-spheres contained drug is water miscible cephalo-type, quinolones and beta-lactam antibiotic described, drug release time 3～7 days.
The mass concentration of described antibacterials sustained-release micro-spheres is 1～2%.
The invention has the beneficial effects as follows: the medicinal liquid being stored in pearl core through hole is effectively sent in operation shellfish body while carrying out planting core operation, antibiotics in medicinal liquid can directly play antibacterial and anti-inflammation functions, and medicament slow-release microsphere sustained release drug plays anti-inflammation and the effect promoting pearl sac to be formed, the most effectively prevention Zhi He shellfish wound tissue and the inflammatory reaction of mantle piece, reduce Margarita flaw and the ratio of flaw Margarita, improve pearl quality.
Detailed description of the invention
Being described in further details the present invention below by example, these examples are only used for the present invention is described, do not limit the scope of the invention；
Embodiment 1
A kind of method reducing nucleated pearl flaw, comprises the following steps:
(1) pearl core pre-treatment: bore the through hole of 1 diameter 0.5mm with puncher on pearl core, then cleaned up by the pearl core of boring, be placed in clean fresh water after scalding, dries, standby；
(2) preparating liquid: sodium carboxymethyl cellulose (CMC-Na), antibacterials are made into aqueous solution, then add antibacterials sustained-release micro-spheres, stirring in the solution configured, makes antibacterials sustained-release micro-spheres be evenly distributed, prepare medicinal liquid；
(3) pearl core processes: put in medicinal liquid configure by pearl core punch, sterilizing, dry, and stirs, and allows full medicinal liquid in the through hole on pearl core；
(4) plant core to be administered: in the pearl renucleation Margarita body that will process with nucleus sending device, the medicine in pearl core through hole is admitted in Margarita body simultaneously；
(5) sheet is sent: traditionally implant external carbon dosage small pieces, and make it be close to pearl core；
(6) grow cultured pearls in sea area: the pearly shellfish completing to plant core operation is placed in sea area cultivation 6 months；
Described pearl core is tradition pearl core, the pearl core i.e. made by mussel or sea water Concha Tridacna squamosa shell；
In described medicinal liquid, CMC-Na's act as being formed the hydrosol, the viscosity of increase medicinal liquid, beneficially medicament slow-release microsphere being uniformly distributed in medicinal liquid；
The mass concentration of described sodium carboxymethyl cellulose (CMC-Na) is 1%；
Described antibacterials are water miscible cephalosporins, and mass concentration is 1%；
Described antibacterials sustained-release micro-spheres contained drug is water miscible cephalosporins, and mass concentration is 1%, drug release time 3 days.
Embodiment 2
A kind of method reducing nucleated pearl flaw, comprises the following steps:
(1) pearl core pre-treatment: bore the through hole of 2 diameter 0.8mm with puncher on pearl core, then cleaned up by the pearl core of boring, be placed in clean fresh water after scalding, dries, standby；
(2) preparating liquid: sodium carboxymethyl cellulose (CMC-Na), antibacterials are made into aqueous solution, then add antibacterials sustained-release micro-spheres, stirring in the solution configured, makes antibacterials sustained-release micro-spheres be evenly distributed, prepare medicinal liquid；
(3) pearl core processes: put in medicinal liquid configure by pearl core punch, sterilizing, dry, and stirs, and allows full medicinal liquid in the through hole on pearl core；
(4) plant core to be administered: in the pearl renucleation Margarita body that will process with nucleus sending device, the medicine in pearl core through hole is admitted in Margarita body simultaneously；
(5) sheet is sent: traditionally implant external carbon dosage small pieces, and make it be close to pearl core；
(6) grow cultured pearls in sea area: the pearly shellfish completing to plant core operation is placed in sea area cultivation 12 months；
Described pearl core is tradition pearl core, the pearl core i.e. made by mussel or sea water Concha Tridacna squamosa shell；
In described medicinal liquid, CMC-Na's act as being formed the hydrosol, the viscosity of increase medicinal liquid, beneficially medicament slow-release microsphere being uniformly distributed in medicinal liquid；
The mass concentration of described sodium carboxymethyl cellulose (CMC-Na) is 2%；
Described antibacterials are quinolone antibiotic, and mass concentration is 2%；
Described antibacterials sustained-release micro-spheres contained drug is quinolone antibiotic, and mass concentration is 2%, drug release time 7 days.
Embodiment 3
A kind of method reducing nucleated pearl flaw, comprises the following steps:
(1) pearl core pre-treatment: bore the through hole of 1 diameter 0.6mm with puncher on pearl core, then cleaned up by the pearl core of boring, be placed in clean fresh water after scalding, dries, standby；
(2) preparating liquid: sodium carboxymethyl cellulose (CMC-Na), antibacterials are made into aqueous solution, then add antibacterials sustained-release micro-spheres, stirring in the solution configured, makes antibacterials sustained-release micro-spheres be evenly distributed, prepare medicinal liquid；
(3) pearl core processes: put in medicinal liquid configure by pearl core punch, sterilizing, dry, and stirs, and allows full medicinal liquid in the through hole on pearl core；
(4) plant core to be administered: in the pearl renucleation Margarita body that will process with nucleus sending device, the medicine in pearl core through hole is admitted in Margarita body simultaneously；
(5) sheet is sent: traditionally implant external carbon dosage small pieces, and make it be close to pearl core；
(6) grow cultured pearls in sea area: the pearly shellfish completing to plant core operation is placed in sea area cultivation 9 months；
Described pearl core is tradition pearl core, the pearl core i.e. made by mussel or sea water Concha Tridacna squamosa shell；
In described medicinal liquid, CMC-Na's act as being formed the hydrosol, the viscosity of increase medicinal liquid, beneficially medicament slow-release microsphere being uniformly distributed in medicinal liquid；
The mass concentration of described sodium carboxymethyl cellulose (CMC-Na) is 1%；
Described antibacterials are beta-lactam antibiotic, and mass concentration is 1%；
Described antibacterials sustained-release micro-spheres contained drug is beta-lactam antibiotic, and mass concentration is 1%, drug release time 4 days.
Embodiment 4
A kind of method reducing nucleated pearl flaw, comprises the following steps:
(1) pearl core pre-treatment: bore the through hole of 2 diameter 0.7mm with puncher on pearl core, then cleaned up by the pearl core of boring, be placed in clean fresh water after scalding, dries, standby；
(2) preparating liquid: sodium carboxymethyl cellulose (CMC-Na), antibacterials are made into aqueous solution, then add antibacterials sustained-release micro-spheres, stirring in the solution configured, makes antibacterials sustained-release micro-spheres be evenly distributed, prepare medicinal liquid；
(3) pearl core processes: put in medicinal liquid configure by pearl core punch, sterilizing, dry, and stirs, and allows full medicinal liquid in the through hole on pearl core；
(4) plant core to be administered: in the pearl renucleation Margarita body that will process with nucleus sending device, the medicine in pearl core through hole is admitted in Margarita body simultaneously；
(5) sheet is sent: traditionally implant external carbon dosage small pieces, and make it be close to pearl core；
(6) grow cultured pearls in sea area: the pearly shellfish completing to plant core operation is placed in sea area cultivation 7 months；
Described pearl core is tradition pearl core, the pearl core i.e. made by mussel or sea water Concha Tridacna squamosa shell；
In described medicinal liquid, CMC-Na's act as being formed the hydrosol, the viscosity of increase medicinal liquid, beneficially medicament slow-release microsphere being uniformly distributed in medicinal liquid；
The mass concentration of described sodium carboxymethyl cellulose (CMC-Na) is 2%；
Described antibacterials are quinolones and beta-lactam antibiotic, and mass concentration is 2%；
Described antibacterials sustained-release micro-spheres contained drug is quinolones and beta-lactam antibiotic, and mass concentration is 2%, drug release time 6 days.
Embodiment 5
A kind of method reducing nucleated pearl flaw, comprises the following steps:
(1) pearl core pre-treatment: bore the through hole of 1 diameter 0.7mm with puncher on pearl core, then cleaned up by the pearl core of boring, be placed in clean fresh water after scalding, dries, standby；
(2) preparating liquid: sodium carboxymethyl cellulose (CMC-Na), antibacterials are made into aqueous solution, then add antibacterials sustained-release micro-spheres, stirring in the solution configured, makes antibacterials sustained-release micro-spheres be evenly distributed, prepare medicinal liquid；
(3) pearl core processes: put in medicinal liquid configure by pearl core punch, sterilizing, dry, and stirs, and allows full medicinal liquid in the through hole on pearl core；
(4) plant core to be administered: in the pearl renucleation Margarita body that will process with nucleus sending device, the medicine in pearl core through hole is admitted in Margarita body simultaneously；
(5) sheet is sent: traditionally implant external carbon dosage small pieces, and make it be close to pearl core；
(6) grow cultured pearls in sea area: the pearly shellfish completing to plant core operation is placed in sea area cultivation 10 months；
Described pearl core is tradition pearl core, the pearl core i.e. made by mussel or sea water Concha Tridacna squamosa shell；
In described medicinal liquid, CMC-Na's act as being formed the hydrosol, the viscosity of increase medicinal liquid, beneficially medicament slow-release microsphere being uniformly distributed in medicinal liquid；
The mass concentration of described sodium carboxymethyl cellulose (CMC-Na) is 2%；
Described antibacterials are water miscible cephalo-type and beta-lactam antibiotic, and mass concentration is 2%；
Described antibacterials sustained-release micro-spheres contained drug is water miscible cephalo-type and beta-lactam antibiotic, and mass concentration is 2%, drug release time 5 days.
Claims (2)
1. the method reducing nucleated pearl flaw, it is characterised in that: comprise the following steps:
(1) pearl core pre-treatment: bore the through hole of 1～2 diameter 0.5～0.8mm with puncher on pearl core, then cleaned up by the pearl core of boring, be placed in clean fresh water after scalding, dries, standby；
(2) preparating liquid: sodium carboxymethyl cellulose CMC-Na, antibacterials are made into aqueous solution, then add antibacterials sustained-release micro-spheres, stirring in the solution configured, makes antibacterials sustained-release micro-spheres be evenly distributed, prepare medicinal liquid；
(3) pearl core processes: put in medicinal liquid configure by pearl core punch, sterilizing, dry, and stirs, and allows full medicinal liquid in the through hole on pearl core；
(4) plant core to be administered: in the pearl renucleation Margarita body that will process with nucleus sending device, the medicine in pearl core through hole is admitted in Margarita body simultaneously；
(5) sheet is sent: traditionally implant external carbon dosage small pieces, and make it be close to pearl core；
(6) grow cultured pearls in sea area: the pearly shellfish completing to plant core operation is placed in sea area cultivation 6～12 months；
Wherein the mass concentration of the sodium carboxymethyl cellulose CMC-Na described in step (2) is 1～2%；
Wherein described in step (2) antibacterials are water miscible cephalo-type, quinolones and beta-lactam antibiotic one or more；
Wherein the mass concentration of the antibacterials described in step (2) is 1～2%；
Wherein the mass concentration of the antibacterials sustained-release micro-spheres described in step (2) is 1～2%.
A kind of method reducing nucleated pearl flaw the most according to claim 1, it is characterized in that: described in step (2) antibacterials sustained-release micro-spheres contained drug is water miscible cephalo-type, quinolones and beta-lactam antibiotic one or more, drug release time 3～7 days.
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| CN104855315B (en) * | 2015-05-20 | 2017-06-30 | 广西南珠宫投资控股集团有限公司 | A kind of cultural method of colored anion pearl |
| CN106305561B (en) * | 2016-08-15 | 2022-07-08 | 郭伟锋 | Automatic pipe network type pearl mussel feeding system |
Citations (4)
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|---|---|---|---|---|
| CN101036449A (en) * | 2007-04-24 | 2007-09-19 | 詹伟建 | Pearl sacs processing method for cultivating nucleated pearls |
| JP4040413B2 (en) * | 2002-09-30 | 2008-01-30 | 琉球真珠株式会社 | Nucleation method of pearl shell |
| CN101803580A (en) * | 2010-04-21 | 2010-08-18 | 广西壮族自治区海洋研究所 | Pearl nucleus active liquid used for saltwater pearl culture and preparation method thereof |
| CN102257973A (en) * | 2011-04-28 | 2011-11-30 | 广东海洋大学 | Method for preparing antibacterial nuclei |
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2014
- 2014-12-04 CN CN201410726688.1A patent/CN104381179B/en active Active
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4040413B2 (en) * | 2002-09-30 | 2008-01-30 | 琉球真珠株式会社 | Nucleation method of pearl shell |
| CN101036449A (en) * | 2007-04-24 | 2007-09-19 | 詹伟建 | Pearl sacs processing method for cultivating nucleated pearls |
| CN101803580A (en) * | 2010-04-21 | 2010-08-18 | 广西壮族自治区海洋研究所 | Pearl nucleus active liquid used for saltwater pearl culture and preparation method thereof |
| CN102257973A (en) * | 2011-04-28 | 2011-11-30 | 广东海洋大学 | Method for preparing antibacterial nuclei |
Non-Patent Citations (2)
| Title |
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| 中药对合浦珠母贝插核手术伤口愈合效果和珍珠质量的影响;张希 等;《海洋科学》;20111231;第35卷(第6期);第25-29页 * |
| 术前处理和室内水池休养对提高珍珠产量和质量的影响;谢仁政 等;《海洋科学》;19991231(第4期);第14-16页 * |
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Effective date of registration: 20190621 Address after: 570216 Jingrun Pearl Building, No. 16-8 Construction Road, Jinpan District, Longhua District, Haikou City, Hainan Province Patentee after: Hainan Runzhu Technology Co., Ltd. Address before: 524000 Guangdong Ocean University, Zhanjiang, Guangdong. Patentee before: Guangdong Ocean University |