JP2567043B2 - 分散用部材を有する有用薬剤投与用製剤 - Google Patents
分散用部材を有する有用薬剤投与用製剤Info
- Publication number
- JP2567043B2 JP2567043B2 JP63164857A JP16485788A JP2567043B2 JP 2567043 B2 JP2567043 B2 JP 2567043B2 JP 63164857 A JP63164857 A JP 63164857A JP 16485788 A JP16485788 A JP 16485788A JP 2567043 B2 JP2567043 B2 JP 2567043B2
- Authority
- JP
- Japan
- Prior art keywords
- carrier
- formulation
- environment
- useful
- administration
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
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- VWRCYAZJKNPEQR-NIEARKAZSA-N (2r,3r)-2,3-dihydroxybutanedioic acid;1-methyl-2-[(e)-2-thiophen-2-ylethenyl]-5,6-dihydro-4h-pyrimidine Chemical compound OC(=O)[C@H](O)[C@@H](O)C(O)=O.CN1CCCN=C1\C=C\C1=CC=CS1 VWRCYAZJKNPEQR-NIEARKAZSA-N 0.000 description 3
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- 229940124530 sulfonamide Drugs 0.000 description 1
- 150000003456 sulfonamides Chemical class 0.000 description 1
- MLKXDPUZXIRXEP-MFOYZWKCSA-N sulindac Chemical compound CC1=C(CC(O)=O)C2=CC(F)=CC=C2\C1=C/C1=CC=C(S(C)=O)C=C1 MLKXDPUZXIRXEP-MFOYZWKCSA-N 0.000 description 1
- 229960000894 sulindac Drugs 0.000 description 1
- 229910021653 sulphate ion Inorganic materials 0.000 description 1
- 230000000153 supplemental effect Effects 0.000 description 1
- 230000001975 sympathomimetic effect Effects 0.000 description 1
- 229940064707 sympathomimetics Drugs 0.000 description 1
- 230000000946 synaptic effect Effects 0.000 description 1
- 238000010189 synthetic method Methods 0.000 description 1
- 229940095064 tartrate Drugs 0.000 description 1
- IWVCMVBTMGNXQD-UHFFFAOYSA-N terramycin dehydrate Natural products C1=CC=C2C(O)(C)C3C(O)C4C(N(C)C)C(O)=C(C(N)=O)C(=O)C4(O)C(O)=C3C(=O)C2=C1O IWVCMVBTMGNXQD-UHFFFAOYSA-N 0.000 description 1
- RBTVSNLYYIMMKS-UHFFFAOYSA-N tert-butyl 3-aminoazetidine-1-carboxylate;hydrochloride Chemical compound Cl.CC(C)(C)OC(=O)N1CC(N)C1 RBTVSNLYYIMMKS-UHFFFAOYSA-N 0.000 description 1
- 229960002180 tetracycline Drugs 0.000 description 1
- 235000019364 tetracycline Nutrition 0.000 description 1
- 229930101283 tetracycline Natural products 0.000 description 1
- 150000003522 tetracyclines Chemical class 0.000 description 1
- YLQBMQCUIZJEEH-UHFFFAOYSA-N tetrahydrofuran Natural products C=1C=COC=1 YLQBMQCUIZJEEH-UHFFFAOYSA-N 0.000 description 1
- 239000004308 thiabendazole Substances 0.000 description 1
- 229960004546 thiabendazole Drugs 0.000 description 1
- 235000010296 thiabendazole Nutrition 0.000 description 1
- WJCNZQLZVWNLKY-UHFFFAOYSA-N thiabendazole Chemical compound S1C=NC(C=2NC3=CC=CC=C3N=2)=C1 WJCNZQLZVWNLKY-UHFFFAOYSA-N 0.000 description 1
- 229960004869 thiethylperazine Drugs 0.000 description 1
- RVBRTNPNFYFDMZ-SPIKMXEPSA-N thiethylperazine maleate Chemical compound [H+].[H+].[H+].[H+].[O-]C(=O)\C=C/C([O-])=O.[O-]C(=O)\C=C/C([O-])=O.C12=CC(SCC)=CC=C2SC2=CC=CC=C2N1CCCN1CCN(C)CC1 RVBRTNPNFYFDMZ-SPIKMXEPSA-N 0.000 description 1
- 229960004605 timolol Drugs 0.000 description 1
- OGIDPMRJRNCKJF-UHFFFAOYSA-N titanium oxide Inorganic materials [Ti]=O OGIDPMRJRNCKJF-UHFFFAOYSA-N 0.000 description 1
- 229960001017 tolmetin Drugs 0.000 description 1
- UPSPUYADGBWSHF-UHFFFAOYSA-N tolmetin Chemical compound C1=CC(C)=CC=C1C(=O)C1=CC=C(CC(O)=O)N1C UPSPUYADGBWSHF-UHFFFAOYSA-N 0.000 description 1
- 235000010487 tragacanth Nutrition 0.000 description 1
- 239000000196 tragacanth Substances 0.000 description 1
- 229940116362 tragacanth Drugs 0.000 description 1
- 238000012549 training Methods 0.000 description 1
- 239000003204 tranquilizing agent Substances 0.000 description 1
- 230000002936 tranquilizing effect Effects 0.000 description 1
- 229960002622 triacetin Drugs 0.000 description 1
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
- PVNIQBQSYATKKL-UHFFFAOYSA-N tripalmitin Chemical compound CCCCCCCCCCCCCCCC(=O)OCC(OC(=O)CCCCCCCCCCCCCCC)COC(=O)CCCCCCCCCCCCCCC PVNIQBQSYATKKL-UHFFFAOYSA-N 0.000 description 1
- WDRCVXGINNJWPH-UHFFFAOYSA-N tris(6-methylheptyl) benzene-1,2,4-tricarboxylate Chemical compound CC(C)CCCCCOC(=O)C1=CC=C(C(=O)OCCCCCC(C)C)C(C(=O)OCCCCCC(C)C)=C1 WDRCVXGINNJWPH-UHFFFAOYSA-N 0.000 description 1
- YPDXSCXISVYHOB-UHFFFAOYSA-N tris(7-methyloctyl) benzene-1,2,4-tricarboxylate Chemical compound CC(C)CCCCCCOC(=O)C1=CC=C(C(=O)OCCCCCCC(C)C)C(C(=O)OCCCCCCC(C)C)=C1 YPDXSCXISVYHOB-UHFFFAOYSA-N 0.000 description 1
- OUYCCCASQSFEME-UHFFFAOYSA-N tyrosine Natural products OC(=O)C(N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-UHFFFAOYSA-N 0.000 description 1
- 229960004441 tyrosine Drugs 0.000 description 1
- 230000002485 urinary effect Effects 0.000 description 1
- 229960002726 vincamine Drugs 0.000 description 1
- 229920002554 vinyl polymer Polymers 0.000 description 1
- 235000019155 vitamin A Nutrition 0.000 description 1
- 239000011719 vitamin A Substances 0.000 description 1
- 229940045997 vitamin a Drugs 0.000 description 1
- 229920001285 xanthan gum Polymers 0.000 description 1
- 235000010493 xanthan gum Nutrition 0.000 description 1
- 239000000230 xanthan gum Substances 0.000 description 1
- 229940082509 xanthan gum Drugs 0.000 description 1
- 239000008096 xylene Substances 0.000 description 1
- 239000005019 zein Substances 0.000 description 1
- 229940093612 zein Drugs 0.000 description 1
- PAPBSGBWRJIAAV-UHFFFAOYSA-N ε-Caprolactone Chemical compound O=C1CCCCCO1 PAPBSGBWRJIAAV-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
- A61M31/002—Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Anesthesiology (AREA)
- Hematology (AREA)
- Heart & Thoracic Surgery (AREA)
- Biomedical Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Medicinal Preparation (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US69148 | 1987-07-02 | ||
| US07/069,148 US4876093A (en) | 1987-07-02 | 1987-07-02 | Dispenser with dispersing member for delivering beneficial agent |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS6429304A JPS6429304A (en) | 1989-01-31 |
| JP2567043B2 true JP2567043B2 (ja) | 1996-12-25 |
Family
ID=22087061
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP63164857A Expired - Lifetime JP2567043B2 (ja) | 1987-07-02 | 1988-07-01 | 分散用部材を有する有用薬剤投与用製剤 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US4876093A (enExample) |
| EP (1) | EP0297725B1 (enExample) |
| JP (1) | JP2567043B2 (enExample) |
| KR (1) | KR890001598A (enExample) |
| AU (1) | AU613039B2 (enExample) |
| CA (1) | CA1285444C (enExample) |
| DE (1) | DE3871256D1 (enExample) |
| ES (1) | ES2031597T3 (enExample) |
| GR (1) | GR3004653T3 (enExample) |
| ZA (1) | ZA883911B (enExample) |
Families Citing this family (63)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4983400A (en) * | 1986-06-16 | 1991-01-08 | Merck & Co., Inc. | Controlled release combination of carbidopa/levodopa |
| US5108756A (en) * | 1989-01-12 | 1992-04-28 | Pfizer Inc. | Dispensing devices powered by lyotropic liquid crystals |
| JPH02229880A (ja) * | 1989-02-08 | 1990-09-12 | Ajinomoto Co Inc | 吹き付けアスベスト除去用組成物及び吹き付けアスベスト除去方法 |
| US5002540A (en) * | 1989-05-22 | 1991-03-26 | Warren Kirschbaum | Intravaginal device and method for delivering a medicament |
| US5273752A (en) * | 1989-07-18 | 1993-12-28 | Alza Corporation | Controlled release dispenser comprising beneficial agent |
| US5112614A (en) * | 1989-09-14 | 1992-05-12 | Alza Corporation | Implantable delivery dispenser |
| ES2082194T3 (es) * | 1990-01-24 | 1996-03-16 | Alza Corp | Sistema de aporte que comprende medios para controlar la presion interna. |
| US5229133A (en) * | 1990-01-24 | 1993-07-20 | Alza Corporation | Delivery system comprising means for controlling internal pressure |
| US5213809A (en) * | 1990-01-24 | 1993-05-25 | Alza Corporation | Delivery system comprising means for controlling internal pressure |
| US5122128A (en) * | 1990-03-15 | 1992-06-16 | Alza Corporation | Orifice insert for a ruminal bolus |
| NL9002215A (nl) * | 1990-10-11 | 1992-05-06 | Texas Instruments Holland | Werkwijze voor het inbrengen van een transponder samen met een desinfecterend middel alsmede dit middel. |
| US5240713A (en) * | 1991-09-27 | 1993-08-31 | Alza Corporation | Dual rate agent delivery device |
| US5462741A (en) * | 1992-08-06 | 1995-10-31 | Alza Corporation | High agent loaded controlled release dispenser |
| US6498153B1 (en) | 1998-12-31 | 2002-12-24 | Akzo Nobel N.V. | Extended release growth promoting two component composition |
| NZ517094A (en) * | 2002-02-08 | 2005-03-24 | Advanced Animal Technology Ltd | Improvements in and relating to substance delivery device |
| US9198608B2 (en) | 2005-04-28 | 2015-12-01 | Proteus Digital Health, Inc. | Communication system incorporated in a container |
| US8802183B2 (en) | 2005-04-28 | 2014-08-12 | Proteus Digital Health, Inc. | Communication system with enhanced partial power source and method of manufacturing same |
| US8836513B2 (en) | 2006-04-28 | 2014-09-16 | Proteus Digital Health, Inc. | Communication system incorporated in an ingestible product |
| US8912908B2 (en) | 2005-04-28 | 2014-12-16 | Proteus Digital Health, Inc. | Communication system with remote activation |
| CN103259027A (zh) | 2005-04-28 | 2013-08-21 | 普罗透斯数字保健公司 | 药物信息系统 |
| US8778395B2 (en) | 2005-08-11 | 2014-07-15 | Andrx Labs, Llc | Diltiazem controlled release formulation and method of manufacture |
| DK3326681T3 (da) * | 2005-12-30 | 2019-09-30 | Rdd Pharma Ltd | Indretning til behandling af analsphincteren |
| US8956287B2 (en) | 2006-05-02 | 2015-02-17 | Proteus Digital Health, Inc. | Patient customized therapeutic regimens |
| MY158019A (en) | 2006-10-25 | 2016-08-30 | Proteus Digital Health Inc | Controlled activation ingestible identifier |
| WO2008063626A2 (en) | 2006-11-20 | 2008-05-29 | Proteus Biomedical, Inc. | Active signal processing personal health signal receivers |
| MY165368A (en) | 2007-02-01 | 2018-03-21 | Proteus Digital Health Inc | Ingestible event marker systems |
| WO2008101107A1 (en) | 2007-02-14 | 2008-08-21 | Proteus Biomedical, Inc. | In-body power source having high surface area electrode |
| WO2008112578A1 (en) | 2007-03-09 | 2008-09-18 | Proteus Biomedical, Inc. | In-body device having a deployable antenna |
| US8932221B2 (en) | 2007-03-09 | 2015-01-13 | Proteus Digital Health, Inc. | In-body device having a multi-directional transmitter |
| US8115618B2 (en) | 2007-05-24 | 2012-02-14 | Proteus Biomedical, Inc. | RFID antenna for in-body device |
| EP4011289A1 (en) | 2007-09-25 | 2022-06-15 | Otsuka Pharmaceutical Co., Ltd. | In-body device with virtual dipole signal amplification |
| SG190590A1 (en) | 2007-11-27 | 2013-06-28 | Proteus Digital Health Inc | Transbody communication systems employing communication channels |
| PT3235491T (pt) | 2008-03-05 | 2021-01-04 | Proteus Digital Health Inc | Marcadores de evento ingestíveis de comunicação multi-modo e sistemas |
| KR101615128B1 (ko) | 2008-07-08 | 2016-04-26 | 프로테우스 디지털 헬스, 인코포레이티드 | 섭취 가능한 이벤트 마커 데이터 프레임워크 |
| US8540633B2 (en) | 2008-08-13 | 2013-09-24 | Proteus Digital Health, Inc. | Identifier circuits for generating unique identifiable indicators and techniques for producing same |
| TWI602561B (zh) | 2009-01-06 | 2017-10-21 | 波提亞斯數位康健公司 | 醫藥劑量傳送系統 |
| EP2385781A4 (en) | 2009-01-06 | 2014-11-05 | Proteus Digital Health Inc | BIOLOGICAL FEEDBACK RELATED TO INGESTION AND PERSONALIZED MEDICAL TREATMENT METHOD AND SYSTEM |
| WO2010111403A2 (en) | 2009-03-25 | 2010-09-30 | Proteus Biomedical, Inc. | Probablistic pharmacokinetic and pharmacodynamic modeling |
| SG175388A1 (en) | 2009-04-28 | 2011-12-29 | Proteus Biomedical Inc | Highly reliable ingestible event markers and methods for using the same |
| WO2010132331A2 (en) | 2009-05-12 | 2010-11-18 | Proteus Biomedical, Inc. | Ingestible event markers comprising an ingestible component |
| EP2445481B1 (en) | 2009-06-18 | 2017-03-22 | Rdd Pharma Ltd. | Methods and devices for delivery of pharmaceutical agents within orifices of the body |
| TWI517050B (zh) | 2009-11-04 | 2016-01-11 | 普羅托斯數位健康公司 | 供應鏈管理之系統 |
| UA109424C2 (uk) | 2009-12-02 | 2015-08-25 | Фармацевтичний продукт, фармацевтична таблетка з електронним маркером і спосіб виготовлення фармацевтичної таблетки | |
| TWI638652B (zh) | 2010-04-07 | 2018-10-21 | 波提亞斯數位康健公司 | 微型可攝取裝置 |
| TWI557672B (zh) | 2010-05-19 | 2016-11-11 | 波提亞斯數位康健公司 | 用於從製造商跟蹤藥物直到患者之電腦系統及電腦實施之方法、用於確認將藥物給予患者的設備及方法、患者介面裝置 |
| JP2014504902A (ja) | 2010-11-22 | 2014-02-27 | プロテウス デジタル ヘルス， インコーポレイテッド | 医薬品を有する摂取可能なデバイス |
| WO2015112603A1 (en) | 2014-01-21 | 2015-07-30 | Proteus Digital Health, Inc. | Masticable ingestible product and communication system therefor |
| US9756874B2 (en) | 2011-07-11 | 2017-09-12 | Proteus Digital Health, Inc. | Masticable ingestible product and communication system therefor |
| BR112014001397A2 (pt) | 2011-07-21 | 2017-02-21 | Proteus Biomedical Inc | dispositivo, sistema e método de comunicação móvel |
| US9235683B2 (en) | 2011-11-09 | 2016-01-12 | Proteus Digital Health, Inc. | Apparatus, system, and method for managing adherence to a regimen |
| BR112015001388A2 (pt) | 2012-07-23 | 2017-07-04 | Proteus Digital Health Inc | técnicas para fabricar marcadores de eventos ingeríveis que compreendem um componente ingerível |
| AU2013331417B2 (en) | 2012-10-18 | 2016-06-02 | Proteus Digital Health, Inc. | Apparatus, system, and method to adaptively optimize power dissipation and broadcast power in a power source for a communication device |
| US11149123B2 (en) | 2013-01-29 | 2021-10-19 | Otsuka Pharmaceutical Co., Ltd. | Highly-swellable polymeric films and compositions comprising the same |
| US10175376B2 (en) | 2013-03-15 | 2019-01-08 | Proteus Digital Health, Inc. | Metal detector apparatus, system, and method |
| JP6511439B2 (ja) | 2013-06-04 | 2019-05-15 | プロテウス デジタル ヘルス， インコーポレイテッド | データ収集および転帰の査定のためのシステム、装置、および方法 |
| US9796576B2 (en) | 2013-08-30 | 2017-10-24 | Proteus Digital Health, Inc. | Container with electronically controlled interlock |
| US10084880B2 (en) | 2013-11-04 | 2018-09-25 | Proteus Digital Health, Inc. | Social media networking based on physiologic information |
| US11051543B2 (en) | 2015-07-21 | 2021-07-06 | Otsuka Pharmaceutical Co. Ltd. | Alginate on adhesive bilayer laminate film |
| AU2017300786B2 (en) | 2016-07-22 | 2020-03-05 | Otsuka Pharmaceutical Co., Ltd. | Electromagnetic sensing and detection of ingestible event markers |
| JP2019535377A (ja) | 2016-10-26 | 2019-12-12 | プロテウス デジタル ヘルス， インコーポレイテッド | 摂取可能なイベントマーカを有するカプセルの製造方法 |
| WO2021092076A1 (en) * | 2019-11-05 | 2021-05-14 | Bionaut Labs Ltd. | A system and miniature devices for delivering a therapeutic component to a treatment site in a patient |
| FI4037666T3 (fi) | 2020-12-08 | 2024-06-24 | Ruminant Biotech Corp Ltd | Parannuksia laitteisiin ja menetelmiin aineiden toimittamiseksi eläimille |
| CN113289232B (zh) * | 2021-05-08 | 2022-08-30 | 贵州大学 | 一种治疗肤癣菌病用纳米药物上药装置 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2893032A (en) * | 1956-11-29 | 1959-07-07 | Selmer Alois | Corn buttering device |
| US3995632A (en) * | 1973-05-04 | 1976-12-07 | Alza Corporation | Osmotic dispenser |
| AU520409B2 (en) * | 1977-05-25 | 1982-01-28 | Commonwealth Scientific And Industrial Research Organisation | Controlled release composition |
| US4350271A (en) * | 1980-08-22 | 1982-09-21 | Alza Corporation | Water absorbing fluid dispenser |
| US4327725A (en) * | 1980-11-25 | 1982-05-04 | Alza Corporation | Osmotic device with hydrogel driving member |
| US4408919A (en) * | 1981-10-09 | 1983-10-11 | Dart Industries Inc. | Corn buttering and salting apparatus |
| US4612008A (en) * | 1983-05-11 | 1986-09-16 | Alza Corporation | Osmotic device with dual thermodynamic activity |
| US4595583A (en) * | 1984-03-19 | 1986-06-17 | Alza Corporation | Delivery system controlled administration of beneficial agent to ruminants |
| US4609374A (en) * | 1985-04-22 | 1986-09-02 | Alza Corporation | Osmotic device comprising means for governing initial time of agent release therefrom |
| US4675174A (en) * | 1985-08-16 | 1987-06-23 | Alza Corporation | Veterinary dispenser delivering beneficial agent by gas power generated in situ |
| US4704118A (en) * | 1985-08-16 | 1987-11-03 | Alza Corporation | Ruminant dispensing device with thermo-activated memory |
-
1987
- 1987-07-02 US US07/069,148 patent/US4876093A/en not_active Expired - Lifetime
-
1988
- 1988-05-19 AU AU16421/88A patent/AU613039B2/en not_active Expired
- 1988-06-01 ES ES198888304973T patent/ES2031597T3/es not_active Expired - Lifetime
- 1988-06-01 DE DE8888304973T patent/DE3871256D1/de not_active Expired - Lifetime
- 1988-06-01 EP EP88304973A patent/EP0297725B1/en not_active Expired - Lifetime
- 1988-06-02 ZA ZA883911A patent/ZA883911B/xx unknown
- 1988-06-21 KR KR1019880007456A patent/KR890001598A/ko not_active Ceased
- 1988-06-30 CA CA000570856A patent/CA1285444C/en not_active Expired - Lifetime
- 1988-07-01 JP JP63164857A patent/JP2567043B2/ja not_active Expired - Lifetime
-
1992
- 1992-05-21 GR GR910402264T patent/GR3004653T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE3871256D1 (de) | 1992-06-25 |
| EP0297725A2 (en) | 1989-01-04 |
| AU613039B2 (en) | 1991-07-25 |
| GR3004653T3 (enExample) | 1993-04-28 |
| ES2031597T3 (es) | 1992-12-16 |
| AU1642188A (en) | 1989-01-05 |
| CA1285444C (en) | 1991-07-02 |
| KR890001598A (ko) | 1989-03-27 |
| EP0297725A3 (en) | 1989-03-22 |
| JPS6429304A (en) | 1989-01-31 |
| EP0297725B1 (en) | 1992-05-20 |
| ZA883911B (en) | 1988-12-19 |
| US4876093A (en) | 1989-10-24 |
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