JP2026041845A5 - - Google Patents
Info
- Publication number
- JP2026041845A5 JP2026041845A5 JP2025210219A JP2025210219A JP2026041845A5 JP 2026041845 A5 JP2026041845 A5 JP 2026041845A5 JP 2025210219 A JP2025210219 A JP 2025210219A JP 2025210219 A JP2025210219 A JP 2025210219A JP 2026041845 A5 JP2026041845 A5 JP 2026041845A5
- Authority
- JP
- Japan
- Prior art keywords
- sequence
- antibody
- antigen
- sequence described
- binding fragment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (8)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010972365 | 2020-09-16 | ||
| CN202010972365.6 | 2020-09-16 | ||
| CN202011624826.7 | 2020-12-31 | ||
| CN202011624826 | 2020-12-31 | ||
| JP2023516174A JP7458686B2 (ja) | 2020-09-16 | 2021-09-06 | 抗ネクチン－４抗体、それを含むコンジュゲート、及びその適用 |
| PCT/CN2021/116651 WO2022057651A1 (zh) | 2020-09-16 | 2021-09-06 | 抗Nectin-4抗体、包含所述抗体的缀合物及其应用 |
| JP2023138150A JP7649826B2 (ja) | 2020-09-16 | 2023-08-28 | 抗ネクチン－４抗体、それを含むコンジュゲート、及びその適用 |
| JP2024209392A JP7784511B2 (ja) | 2020-09-16 | 2024-12-02 | 抗ネクチン－４抗体、それを含むコンジュゲート、及びその適用 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024209392A Division JP7784511B2 (ja) | 2020-09-16 | 2024-12-02 | 抗ネクチン－４抗体、それを含むコンジュゲート、及びその適用 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2026041845A JP2026041845A (ja) | 2026-03-10 |
| JP2026041845A5 true JP2026041845A5 (cg-RX-API-DMAC10.html) | 2026-04-21 |
Family
ID=80777562
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023516174A Active JP7458686B2 (ja) | 2020-09-16 | 2021-09-06 | 抗ネクチン－４抗体、それを含むコンジュゲート、及びその適用 |
| JP2023138151A Active JP7649827B2 (ja) | 2020-09-16 | 2023-08-28 | 抗ネクチン－４抗体、それを含むコンジュゲート、及びその適用 |
| JP2023138150A Active JP7649826B2 (ja) | 2020-09-16 | 2023-08-28 | 抗ネクチン－４抗体、それを含むコンジュゲート、及びその適用 |
| JP2024209392A Active JP7784511B2 (ja) | 2020-09-16 | 2024-12-02 | 抗ネクチン－４抗体、それを含むコンジュゲート、及びその適用 |
| JP2025210219A Pending JP2026041845A (ja) | 2020-09-16 | 2025-12-01 | 抗ネクチン－４抗体、それを含むコンジュゲート、及びその適用 |
Family Applications Before (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023516174A Active JP7458686B2 (ja) | 2020-09-16 | 2021-09-06 | 抗ネクチン－４抗体、それを含むコンジュゲート、及びその適用 |
| JP2023138151A Active JP7649827B2 (ja) | 2020-09-16 | 2023-08-28 | 抗ネクチン－４抗体、それを含むコンジュゲート、及びその適用 |
| JP2023138150A Active JP7649826B2 (ja) | 2020-09-16 | 2023-08-28 | 抗ネクチン－４抗体、それを含むコンジュゲート、及びその適用 |
| JP2024209392A Active JP7784511B2 (ja) | 2020-09-16 | 2024-12-02 | 抗ネクチン－４抗体、それを含むコンジュゲート、及びその適用 |
Country Status (19)
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20250205353A1 (en) | 2022-03-23 | 2025-06-26 | Synaffix B.V. | Antibody-conjugates for targeting of tumours expressing nectin-4 |
| CN117982672A (zh) * | 2022-07-14 | 2024-05-07 | 百奥泰生物制药股份有限公司 | 抗Nectin-4抗体药物偶联物及应用 |
| EP4310101A1 (en) * | 2022-07-22 | 2024-01-24 | Emergence Therapeutics AG | Novel anti-nectin-4 antibodies and antibody-drug conjugates |
| CN117567620B (zh) * | 2023-09-28 | 2026-07-31 | 深圳市汉科生物工程有限公司 | 一种Nectin-4单克隆抗体及其CAR-NK细胞 |
| WO2025162492A1 (zh) * | 2024-01-29 | 2025-08-07 | 甘李药业股份有限公司 | 一种连接子、配体-药物偶联物及其医药用途 |
| CN117986367B (zh) * | 2024-04-02 | 2024-07-16 | 上海美迪西生物医药股份有限公司 | 靶点为Nectin-4的抗体及其应用 |
| KR20250177512A (ko) * | 2024-06-14 | 2025-12-24 | 삼성바이오에피스 주식회사 | 신규한 항-넥틴-4 항체 및 이의 용도 |
| WO2025261506A1 (zh) * | 2024-06-21 | 2025-12-26 | 信达生物制药(苏州)有限公司 | 抗Nectin-4抗体以及其用途 |
| WO2026008043A1 (zh) * | 2024-07-04 | 2026-01-08 | 石药集团巨石生物制药有限公司 | 靶向Nectin-4的抗体药物缀合物和免疫检查点抑制剂联合的用途 |
| WO2026112565A1 (en) * | 2024-11-25 | 2026-05-28 | Merck Sharp & Dohme Llc | Methods and compositions for treatment of cancer with anti-human nectin-4 therapeutics |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1993008829A1 (en) | 1991-11-04 | 1993-05-13 | The Regents Of The University Of California | Compositions that mediate killing of hiv-infected cells |
| ES2874306T3 (es) | 2010-09-29 | 2021-11-04 | Agensys Inc | Conjugados de anticuerpos y fármacos (CAF) que se unen a las proteínas 191P4D12 |
| EP3347048B1 (en) * | 2015-09-09 | 2020-04-01 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Antibodies having specificity to nectin-4 and uses thereof |
| CN106729743B (zh) * | 2015-11-23 | 2021-09-21 | 四川科伦博泰生物医药股份有限公司 | 抗ErbB2抗体-药物偶联物及其组合物、制备方法和应用 |
| US11274160B2 (en) * | 2017-03-02 | 2022-03-15 | INSERM (Institut National de la Santé et de la Recherche Médicale | Antibodies having specificity to Nectin-4 and uses thereof |
| TWI870338B (zh) * | 2017-06-05 | 2025-01-21 | 美商艾澤西公司 | 粘附分子-4結合蛋白及其使用方法 |
| CN119219654A (zh) * | 2017-12-15 | 2024-12-31 | 四川科伦博泰生物医药股份有限公司 | 生物活性物偶联物及其制备方法和用途 |
| US12077583B2 (en) * | 2018-05-09 | 2024-09-03 | Nectin Therapeutics Ltd. | Antibodies specific to human NECTIN4 |
| CN110903395A (zh) * | 2018-09-14 | 2020-03-24 | 四川科伦博泰生物医药股份有限公司 | 抗体、偶联物及其制备方法和用途 |
-
2021
- 2021-09-06 GE GEAP202516220A patent/GEP20267876B/en unknown
- 2021-09-06 CN CN202180062998.6A patent/CN116234564A/zh active Pending
- 2021-09-06 MX MX2023002805A patent/MX2023002805A/es unknown
- 2021-09-06 KR KR1020237008623A patent/KR20230069111A/ko active Pending
- 2021-09-06 US US18/026,576 patent/US20250223352A2/en active Pending
- 2021-09-06 GE GEAP202516662A patent/GEAP202516662A/en unknown
- 2021-09-06 PE PE2023001160A patent/PE20230844A1/es unknown
- 2021-09-06 JP JP2023516174A patent/JP7458686B2/ja active Active
- 2021-09-06 CN CN202311193858.XA patent/CN117285629A/zh active Pending
- 2021-09-06 CR CR20230128A patent/CR20230128A/es unknown
- 2021-09-06 BR BR112022026611A patent/BR112022026611A2/pt unknown
- 2021-09-06 AU AU2021345721A patent/AU2021345721A1/en active Pending
- 2021-09-06 CA CA3194765A patent/CA3194765A1/en active Pending
- 2021-09-06 EP EP21868477.7A patent/EP4215546A4/en active Pending
- 2021-09-06 GE GEAP202616950A patent/GEAP202616950A/en unknown
- 2021-09-06 IL IL301387A patent/IL301387A/en unknown
- 2021-09-06 WO PCT/CN2021/116651 patent/WO2022057651A1/zh not_active Ceased
-
2023
- 2023-03-14 DO DO2023000054A patent/DOP2023000054A/es unknown
- 2023-03-15 CO CONC2023/0003210A patent/CO2023003210A2/es unknown
- 2023-03-15 CL CL2023000741A patent/CL2023000741A1/es unknown
- 2023-03-16 EC ECSENADI202319525A patent/ECSP23019525A/es unknown
- 2023-03-16 JO JOJO/P/2023/0058A patent/JOP20230058A1/ar unknown
- 2023-08-28 JP JP2023138151A patent/JP7649827B2/ja active Active
- 2023-08-28 JP JP2023138150A patent/JP7649826B2/ja active Active
-
2024
- 2024-12-02 JP JP2024209392A patent/JP7784511B2/ja active Active
-
2025
- 2025-06-26 CL CL2025001913A patent/CL2025001913A1/es unknown
- 2025-12-01 JP JP2025210219A patent/JP2026041845A/ja active Pending
-
2026
- 2026-03-18 CL CL2026000802A patent/CL2026000802A1/es unknown