JP2026012402A5 - - Google Patents
Info
- Publication number
- JP2026012402A5 JP2026012402A5 JP2025185622A JP2025185622A JP2026012402A5 JP 2026012402 A5 JP2026012402 A5 JP 2026012402A5 JP 2025185622 A JP2025185622 A JP 2025185622A JP 2025185622 A JP2025185622 A JP 2025185622A JP 2026012402 A5 JP2026012402 A5 JP 2026012402A5
- Authority
- JP
- Japan
- Prior art keywords
- lnp
- nucleic acid
- mol
- tissue
- antigen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962923258P | 2019-10-18 | 2019-10-18 | |
| US62/923,258 | 2019-10-18 | ||
| PCT/US2020/056252 WO2021077066A1 (en) | 2019-10-18 | 2020-10-19 | Lipid and lipid nanoparticle formulation for drug delivery |
| JP2022523031A JP2022552009A (ja) | 2019-10-18 | 2020-10-19 | 薬物送達のための脂質及び脂質ナノ粒子製剤 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022523031A Division JP2022552009A (ja) | 2019-10-18 | 2020-10-19 | 薬物送達のための脂質及び脂質ナノ粒子製剤 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2026012402A JP2026012402A (ja) | 2026-01-23 |
| JP2026012402A5 true JP2026012402A5 (enExample) | 2026-01-30 |
Family
ID=75538682
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022523031A Pending JP2022552009A (ja) | 2019-10-18 | 2020-10-19 | 薬物送達のための脂質及び脂質ナノ粒子製剤 |
| JP2025185622A Pending JP2026012402A (ja) | 2019-10-18 | 2025-11-04 | 薬物送達のための脂質及び脂質ナノ粒子製剤 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022523031A Pending JP2022552009A (ja) | 2019-10-18 | 2020-10-19 | 薬物送達のための脂質及び脂質ナノ粒子製剤 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20220396556A1 (enExample) |
| EP (1) | EP4045020A4 (enExample) |
| JP (2) | JP2022552009A (enExample) |
| KR (1) | KR20220084365A (enExample) |
| CN (1) | CN114828836A (enExample) |
| CA (1) | CA3155074A1 (enExample) |
| WO (1) | WO2021077066A1 (enExample) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2022115645A1 (en) | 2020-11-25 | 2022-06-02 | Akagera Medicines, Inc. | Lipid nanoparticles for delivery of nucleic acids, and related methods of use |
| CN113785975B (zh) * | 2021-09-09 | 2023-08-29 | 天津医科大学 | 精胺、亚精胺脂质体在抗氧化、抗衰老中的应用 |
| AR128959A1 (es) * | 2022-04-04 | 2024-06-26 | Spark Therapeutics Inc | Mejora inmunológica del tratamiento del cáncer |
| CN119325466A (zh) * | 2022-04-08 | 2025-01-17 | 尚威天成信使核糖核酸治疗公司 | 可电离脂质化合物和脂质纳米颗粒组合物 |
| CA3256897A1 (en) | 2022-05-25 | 2023-11-30 | Akagera Medicines, Inc. | Lipid nanoparticles for the administration of nucleic acids and their methods of use |
| CN117264955A (zh) * | 2022-09-23 | 2023-12-22 | 北京键凯科技股份有限公司 | 一种抑制top1基因表达的干扰rna及其应用 |
| WO2024183821A1 (zh) * | 2023-03-09 | 2024-09-12 | 上海吉量医药工程有限公司 | 可离子化脂质分子及其制备方法和应用 |
| CN116082184B (zh) * | 2023-04-12 | 2023-06-30 | 山东大学 | 基于环己二胺的可电离脂质、脂质纳米颗粒及其制备方法与应用 |
| WO2025038494A1 (en) | 2023-08-11 | 2025-02-20 | Tune Therapeutics, Inc. | Compositions, systems, and methods for lymphoid cell differentiation using targeted gene activation |
| WO2025059112A1 (en) * | 2023-09-11 | 2025-03-20 | The Trustees Of The University Of Pennsylvania | Compositions and methods for t cell targeted extrahepatic delivery of therapeutic agents |
| CN117482066B (zh) * | 2023-11-02 | 2024-08-13 | 深圳市易瑞生物技术股份有限公司 | 脂质组合物和用于脂质组合物的化合物 |
| CN121241044A (zh) * | 2024-04-01 | 2025-12-30 | 深圳厚存纳米药业有限公司 | 脂质和脂质纳米颗粒制剂 |
| WO2026003582A2 (en) | 2024-06-27 | 2026-01-02 | Axelyf ehf. | Lipids and lipid nanoparticles |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2740000C (en) * | 2008-10-09 | 2017-12-12 | Tekmira Pharmaceuticals Corporation | Improved amino lipids and methods for the delivery of nucleic acids |
| EP3269395A1 (en) * | 2008-11-07 | 2018-01-17 | Massachusetts Institute Of Technology | Aminoalcohol lipidoids and uses thereof |
| US7635707B1 (en) * | 2008-11-10 | 2009-12-22 | Intermune, Inc. | Pirfenidone treatment for patients with atypical liver function |
| JP6620093B2 (ja) * | 2013-07-23 | 2019-12-11 | アービュートゥス バイオファーマ コーポレイションＡｒｂｕｔｕｓ Ｂｉｏｐｈａｒｍａ Ｃｏｒｐｏｒａｔｉｏｎ | メッセンジャーｒｎａを送達するための組成物及び方法 |
| US20190274968A1 (en) * | 2016-10-27 | 2019-09-12 | The Trustees Of The University Of Pennsylvania | Nucleoside-modified rna for inducing an adaptive immune response |
-
2020
- 2020-10-19 KR KR1020227016630A patent/KR20220084365A/ko not_active Ceased
- 2020-10-19 JP JP2022523031A patent/JP2022552009A/ja active Pending
- 2020-10-19 WO PCT/US2020/056252 patent/WO2021077066A1/en not_active Ceased
- 2020-10-19 CN CN202080088019.XA patent/CN114828836A/zh active Pending
- 2020-10-19 EP EP20877084.2A patent/EP4045020A4/en active Pending
- 2020-10-19 CA CA3155074A patent/CA3155074A1/en active Pending
- 2020-10-19 US US17/769,858 patent/US20220396556A1/en active Pending
-
2025
- 2025-11-04 JP JP2025185622A patent/JP2026012402A/ja active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2026012402A5 (enExample) | ||
| JP2025175052A5 (enExample) | ||
| JP2022552008A5 (enExample) | ||
| JP2022552009A5 (enExample) | ||
| JP4842821B2 (ja) | ポリエチレングリコール修飾脂質化合物およびその使用 | |
| JP2021535227A5 (enExample) | ||
| Dass | Lipoplex-mediated delivery of nucleic acids: factors affecting in vivo transfection | |
| US20200016274A1 (en) | Messenger rna vaccines and uses thereof | |
| JP5977394B2 (ja) | 脂質に封入された干渉ｒｎａ | |
| CN103476431B (zh) | 包含阳离子脂质的用于带负电荷的药物的载体及其制备方法 | |
| US20180245074A1 (en) | Treating hepatitis b virus infection using crispr | |
| US9730893B2 (en) | Lipid assemblies comprising anionic lysolipids and use thereof | |
| JP2001502299A (ja) | リポソーム | |
| JP2001527052A5 (enExample) | ||
| US12485170B2 (en) | Lipid composition targeting antigen-presenting cells and use thereof | |
| JP2024529343A5 (enExample) | ||
| JP2025541727A (ja) | 新規のポリグリセロールコンジュゲート脂質及びそれを含む脂質ナノ粒子組成物 | |
| AU2023211981A1 (en) | Poly(alkyloxazoline)-lipid conjugates and lipid particles containing same | |
| JP2000143549A (ja) | ポリヌクレオチドを細胞にトランスフェクトさせる治療用組成物の製造におけるマグネシウム（Ｍａ２＋）の使用、および遺伝子治療に有用な組成物 | |
| RU2476204C2 (ru) | Носитель лекарственного средства | |
| JP2025540076A (ja) | 核酸、イオン化可能な脂質、ステロール、脂質アンカーポリマー、及びヘルパー脂質を含む脂質ナノ粒子、それらの使用 | |
| JP2005513073A (ja) | ポリヌクレオチドを細胞へトランスフェクションするための組成物の製造のためのリゾ脂質の使用 | |
| JP2005513073A6 (ja) | ポリヌクレオチドを細胞へトランスフェクションするための組成物の製造のためのリゾ脂質の使用 | |
| JP2025505258A (ja) | 疾患の治療方法および／または予防方法に使用するための製剤 | |
| CN117460537A (zh) | 核酸递送 |