JP2025539841A5 - - Google Patents

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Publication number
JP2025539841A5
JP2025539841A5 JP2025529969A JP2025529969A JP2025539841A5 JP 2025539841 A5 JP2025539841 A5 JP 2025539841A5 JP 2025529969 A JP2025529969 A JP 2025529969A JP 2025529969 A JP2025529969 A JP 2025529969A JP 2025539841 A5 JP2025539841 A5 JP 2025539841A5
Authority
JP
Japan
Prior art keywords
amino acid
acid sequence
seq
sequence described
antibody
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2025529969A
Other languages
English (en)
Japanese (ja)
Other versions
JP2025539841A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/IB2023/061813 external-priority patent/WO2024110905A1/en
Publication of JP2025539841A publication Critical patent/JP2025539841A/ja
Publication of JP2025539841A5 publication Critical patent/JP2025539841A5/ja
Pending legal-status Critical Current

Links

JP2025529969A 2022-11-24 2023-11-22 抗cea抗体薬物コンジュゲート及びその使用方法 Pending JP2025539841A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
CNPCT/CN2022/134067 2022-11-24
CN2022134067 2022-11-24
CN2023107003 2023-07-12
CNPCT/CN2023/107003 2023-07-12
PCT/IB2023/061813 WO2024110905A1 (en) 2022-11-24 2023-11-22 Anti-cea antibody drug conjugates and methods of use

Publications (2)

Publication Number Publication Date
JP2025539841A JP2025539841A (ja) 2025-12-09
JP2025539841A5 true JP2025539841A5 (https=) 2026-02-18

Family

ID=88978400

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2025529969A Pending JP2025539841A (ja) 2022-11-24 2023-11-22 抗cea抗体薬物コンジュゲート及びその使用方法

Country Status (13)

Country Link
US (1) US20250115677A1 (https=)
EP (1) EP4622677A1 (https=)
JP (1) JP2025539841A (https=)
KR (1) KR20250111207A (https=)
CN (2) CN120187458A (https=)
AR (1) AR131143A1 (https=)
AU (1) AU2023383923A1 (https=)
CL (1) CL2025001502A1 (https=)
CO (1) CO2025008154A2 (https=)
IL (1) IL320971A (https=)
MX (1) MX2025006057A (https=)
TW (1) TW202434306A (https=)
WO (1) WO2024110905A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN120957753A (zh) * 2023-03-23 2025-11-14 广州百济神州生物制药有限公司 生物活性结合物、其制备方法和其用途
AR133125A1 (es) * 2023-06-29 2025-08-27 Beigene Switzerland Gmbh Conjugados bioactivos, método de preparación y uso de estos
CN121568721A (zh) * 2023-06-29 2026-02-24 广州百济神州生物制药有限公司 生物活性缀合物、其制备方法和其用途

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4376110A (en) 1980-08-04 1983-03-08 Hybritech, Incorporated Immunometric assays using monoclonal antibodies
JP3101690B2 (ja) 1987-03-18 2000-10-23 エス・ビィ・2・インコーポレイテッド 変性抗体の、または変性抗体に関する改良
US5714350A (en) 1992-03-09 1998-02-03 Protein Design Labs, Inc. Increasing antibody affinity by altering glycosylation in the immunoglobulin variable region
AU691811B2 (en) 1993-06-16 1998-05-28 Celltech Therapeutics Limited Antibodies
US5731168A (en) 1995-03-01 1998-03-24 Genentech, Inc. Method for making heteromultimeric polypeptides
US6267958B1 (en) 1995-07-27 2001-07-31 Genentech, Inc. Protein formulation
ATE299938T1 (de) 1997-05-02 2005-08-15 Genentech Inc Ein verfahren zur herstellung multispezifischer antikörper die heteromultimere und gemeinsame komponenten besitzen
US6171586B1 (en) 1997-06-13 2001-01-09 Genentech, Inc. Antibody formulation
US6194551B1 (en) 1998-04-02 2001-02-27 Genentech, Inc. Polypeptide variants
DK1071700T3 (da) 1998-04-20 2010-06-07 Glycart Biotechnology Ag Glykosylerings-modifikation af antistoffer til forbedring af antistofafhængig cellulær cytotoksicitet
PL209392B1 (pl) 1999-01-15 2011-08-31 Genentech Inc Przeciwciało, komórka gospodarza, sposób wytwarzania przeciwciała oraz zastosowanie przeciwciała
CA2704600C (en) 1999-04-09 2016-10-25 Kyowa Kirin Co., Ltd. A method for producing antibodies with increased adcc activity
CA2463879C (en) 2001-10-25 2012-12-04 Genentech, Inc. Glycoprotein compositions
US7871607B2 (en) 2003-03-05 2011-01-18 Halozyme, Inc. Soluble glycosaminoglycanases and methods of preparing and using soluble glycosaminoglycanases
JO3000B1 (ar) 2004-10-20 2016-09-05 Genentech Inc مركبات أجسام مضادة .
DK2439273T3 (da) 2005-05-09 2019-06-03 Ono Pharmaceutical Co Humane monoklonale antistoffer til programmeret død-1(pd-1) og fremgangsmåder til behandling af cancer ved anvendelse af anti-pd-1- antistoffer alene eller i kombination med andre immunterapeutika
BR122017025062B8 (pt) 2007-06-18 2021-07-27 Merck Sharp & Dohme anticorpo monoclonal ou fragmento de anticorpo para o receptor de morte programada humano pd-1, polinucleotídeo e composição compreendendo o referido anticorpo ou fragmento
KR20100058509A (ko) 2007-07-31 2010-06-03 메디뮨 엘엘씨 다중특이적 에피토프 결합 단백질 및 이의 용도
KR101860963B1 (ko) 2010-04-23 2018-05-24 제넨테크, 인크. 이종다량체 단백질의 생산
PE20141017A1 (es) 2011-03-02 2014-08-25 Roche Glycart Ag Anticuerpos del cea
ES2773710T3 (es) 2012-10-11 2020-07-14 Daiichi Sankyo Co Ltd Enlazadores para conjugados de anticuerpo - fármaco
CN105026430B (zh) 2012-11-28 2025-03-25 酵活英属哥伦比亚有限公司 工程化免疫球蛋白重链-轻链对及其用途
CN112552401B (zh) 2013-09-13 2023-08-25 广州百济神州生物制药有限公司 抗pd1抗体及其作为治疗剂与诊断剂的用途
CA2924398A1 (en) * 2013-11-05 2015-05-14 Immunomedics, Inc. Humanized anti-ceacam5 antibody and uses thereof
CA3244731A1 (en) 2014-05-28 2025-11-29 Zymeworks Bc Inc. Modified antigen binding polypeptide constructs and uses thereof
EP3359576B1 (en) 2015-10-08 2024-12-25 Zymeworks BC Inc. Antigen-binding polypeptide constructs comprising kappa and lambda light chains and uses thereof
AU2021335257A1 (en) * 2020-09-04 2023-03-09 Merck Patent Gmbh Anti-CEACAM5 antibodies and conjugates and uses thereof
CA3219672A1 (en) * 2021-05-21 2022-11-24 Liang QU Anti-cea and anti-cd137 multispecific antibodies and methods of use
IL313805A (en) 2021-12-28 2024-08-01 Beigene Switzerland Gmbh Drug antibody conjugates

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