JP2025514326A - ２，４，６－トリヨードフェノール誘導体の製造方法 - Google Patents

２，４，６－トリヨードフェノール誘導体の製造方法 Download PDF

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Publication number
JP2025514326A
JP2025514326A JP2024563632A JP2024563632A JP2025514326A JP 2025514326 A JP2025514326 A JP 2025514326A JP 2024563632 A JP2024563632 A JP 2024563632A JP 2024563632 A JP2024563632 A JP 2024563632A JP 2025514326 A JP2025514326 A JP 2025514326A
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Japan
Prior art keywords
iodination
copper
group
phosphate
compound
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Pending
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JP2024563632A
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Japanese (ja)
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JP2025514326A5 (https=
Inventor
バラニャイ，ジョルト
グイドリン，ニコル
ラッツァーリ，フェデリカ
ウッジェーリ，フルヴィオ
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Bracco Imaging SpA
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Bracco Imaging SpA
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Application filed by Bracco Imaging SpA filed Critical Bracco Imaging SpA
Publication of JP2025514326A publication Critical patent/JP2025514326A/ja
Publication of JP2025514326A5 publication Critical patent/JP2025514326A5/ja
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/12—Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/42—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/44—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring
    • C07C235/48—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring having the nitrogen atom of at least one of the carboxamide groups bound to an acyclic carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP2024563632A 2022-04-29 2023-04-28 ２，４，６－トリヨードフェノール誘導体の製造方法 Pending JP2025514326A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP22170765 2022-04-29
EP22170765.6 2022-04-29
PCT/EP2023/061272 WO2023209165A1 (en) 2022-04-29 2023-04-28 Process for the preparation of 2,4,6-triiodophenol derivatives

Publications (2)

Publication Number Publication Date
JP2025514326A true JP2025514326A (ja) 2025-05-02
JP2025514326A5 JP2025514326A5 (https=) 2025-11-17

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ID=81448941

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Application Number Title Priority Date Filing Date
JP2024563632A Pending JP2025514326A (ja) 2022-04-29 2023-04-28 ２，４，６－トリヨードフェノール誘導体の製造方法

Country Status (6)

Country Link
US (1) US12269790B1 (https=)
EP (1) EP4514771B1 (https=)
JP (1) JP2025514326A (https=)
KR (1) KR20250006017A (https=)
CN (1) CN119095823A (https=)
WO (1) WO2023209165A1 (https=)

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3914294A (en) 1972-06-01 1975-10-21 Squibb & Sons Inc 3,5-Disubstituted-2,4,6-triiodobenzoic acids
CA1327600C (en) 1987-05-22 1994-03-08 Ernest Felder Process for the preparation of 5-acylamino-2,4,6- triiodo-or tribromo-benzoic acid derivatives and corresponding novel 5-acylamino-2,4,6-triiodo or tribromo-benzoic acid derivatives obtained by said process
IT1256248B (it) 1992-12-24 1995-11-29 Bracco Spa Formulazioni iniettabili acquose per radiodiagnostica comprendenti miscele di composti aromatici iodurati utili come agenti opacizzanti ai raggi x
IT1277339B1 (it) 1995-07-25 1997-11-10 Bracco Spa Processo per la produzione di agenti contrastografici iodurati
IT1303797B1 (it) 1998-11-27 2001-02-23 Bracco Spa Processo per la preparazione di n,n'-bis(2,3-diidrossipropil)-5-((idrossiacetil)metilammino)-2,4,6-triiodo-1,3-benzendicarbossammide.
EP2093206A1 (en) 2008-02-20 2009-08-26 BRACCO IMAGING S.p.A. Process for the iodination of aromatic compounds
EP2394984A1 (en) 2010-06-10 2011-12-14 Bracco Imaging S.p.A Process for the iodination of phenolic derivatives

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Publication number Publication date
CN119095823A (zh) 2024-12-06
US12269790B1 (en) 2025-04-08
KR20250006017A (ko) 2025-01-10
EP4514771A1 (en) 2025-03-05
WO2023209165A1 (en) 2023-11-02
US20250109094A1 (en) 2025-04-03
EP4514771B1 (en) 2026-04-15

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