JP2025509995A5 - - Google Patents
Info
- Publication number
- JP2025509995A5 JP2025509995A5 JP2024556197A JP2024556197A JP2025509995A5 JP 2025509995 A5 JP2025509995 A5 JP 2025509995A5 JP 2024556197 A JP2024556197 A JP 2024556197A JP 2024556197 A JP2024556197 A JP 2024556197A JP 2025509995 A5 JP2025509995 A5 JP 2025509995A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- groups
- heterocyclyl
- alkyl
- cycloalkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210330007 | 2022-03-28 | ||
| CN202210330007.4 | 2022-03-28 | ||
| CN202210944231 | 2022-08-05 | ||
| CN202210944231.2 | 2022-08-05 | ||
| CN202211255163.5 | 2022-10-13 | ||
| CN202211255163 | 2022-10-13 | ||
| PCT/CN2023/084265 WO2023185793A1 (zh) | 2022-03-28 | 2023-03-28 | 含氮杂环类化合物、其制备方法及其在医药上的应用 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2025509995A JP2025509995A (ja) | 2025-04-11 |
| JP2025509995A5 true JP2025509995A5 (https=) | 2026-04-06 |
Family
ID=88199144
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024556197A Pending JP2025509995A (ja) | 2022-03-28 | 2023-03-28 | 含窒素複素環系化合物、その調製方法及びその医薬的使用 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20250206760A1 (https=) |
| EP (1) | EP4501925A4 (https=) |
| JP (1) | JP2025509995A (https=) |
| KR (1) | KR20240167844A (https=) |
| CN (1) | CN118715216A (https=) |
| AU (1) | AU2023243776A1 (https=) |
| CA (1) | CA3253847A1 (https=) |
| MX (1) | MX2024011705A (https=) |
| TW (1) | TW202345816A (https=) |
| WO (1) | WO2023185793A1 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW202309022A (zh) | 2021-04-13 | 2023-03-01 | 美商努法倫特公司 | 用於治療具egfr突變之癌症之胺基取代雜環 |
| CN121969632A (zh) * | 2023-09-27 | 2026-05-01 | 江苏恒瑞医药股份有限公司 | 一种喹唑啉衍生物的可药用盐、其结晶形式及用途 |
| CN121969633A (zh) * | 2023-09-27 | 2026-05-01 | 江苏恒瑞医药股份有限公司 | 一种喹唑啉衍生物的结晶形式及其制备方法 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1292591B1 (en) * | 2000-06-22 | 2005-02-02 | Pfizer Products Inc. | Substituted bicyclic derivatives for the treatment of abnormal cell growth |
| DK1660090T3 (da) * | 2003-08-14 | 2012-12-17 | Array Biopharma Inc | Quinazolin-analoger som receptor-tyrosinkinase-inhibitorer |
| ATE446294T1 (de) * | 2005-11-15 | 2009-11-15 | Array Biopharma Inc | N4-phenyl-chinazolin-4-aminderivate und verwandte verbindungen als inhibitoren der erbb-typ-i- rezeptortyrosinkinase zur behandlung hyperproliferativer krankheiten |
| AR092289A1 (es) * | 2011-11-14 | 2015-04-15 | Sunshine Lake Pharma Co Ltd | Derivados de aminoquinazolina y sus sales y metodos de uso |
| CN104744446B (zh) * | 2013-12-30 | 2019-06-25 | 广东东阳光药业有限公司 | 杂芳化合物及其在药物中的应用 |
| WO2017148391A1 (zh) | 2016-03-01 | 2017-09-08 | 上海医药集团股份有限公司 | 一种含氮杂环化合物、制备方法、中间体、组合物和应用 |
| TWI858848B (zh) * | 2018-05-08 | 2024-10-11 | 大陸商迪哲（江蘇）醫藥股份有限公司 | ＥｒｂＢ受體抑制劑 |
| EP4523755A3 (en) * | 2018-09-18 | 2025-06-11 | F. Hoffmann-La Roche AG | Quinazoline derivatives as antitumor agents |
| EP4100409B1 (en) | 2020-02-03 | 2024-08-28 | Boehringer Ingelheim International GmbH | [1,3]diazino[5,4-d]pyrimidines as her2 inhibitors |
| JP7626774B2 (ja) | 2020-02-03 | 2025-02-04 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | ＨＥＲ２阻害薬としての［１，３］ジアジノ［５，４－ｄ］ピリミジン |
| WO2021179274A1 (en) * | 2020-03-13 | 2021-09-16 | Suzhou Zanrong Pharma Ltd. | ErbB RECEPTOR INHIBITORS AS ANTI-TUMOR AGENTS |
| US11608343B2 (en) | 2020-04-24 | 2023-03-21 | Boehringer Ingelheim International Gmbh | Substituted pyrimido[5,4-d]pyrimidines as HER2 inhibitors |
| WO2021231400A1 (en) | 2020-05-12 | 2021-11-18 | Accutar Biotechnology, Inc. | Bis-aryl ethers containing n-acyl azetidine as egfr/her2 inhibitors |
| TW202214654A (zh) | 2020-06-10 | 2022-04-16 | 大陸商江蘇恆瑞醫藥股份有限公司 | 稠合喹唑啉類衍生物、其製備方法及其在醫藥上的應用 |
| TW202214641A (zh) | 2020-06-30 | 2022-04-16 | 美商艾瑞生藥股份有限公司 | Ｈｅｒ２突變抑制劑 |
| US20240398805A1 (en) * | 2021-02-05 | 2024-12-05 | Accutar Biotechnology Inc. | Quinazoline derived compounds as egfr inhibitors and their uses thereof |
| WO2023154124A1 (en) * | 2022-02-09 | 2023-08-17 | Enliven Therapeutics, Inc. | Acylated heterocyclic quinazoline derivatives as inhibitors of erbb2 |
-
2023
- 2023-03-28 CN CN202380022951.6A patent/CN118715216A/zh active Pending
- 2023-03-28 AU AU2023243776A patent/AU2023243776A1/en active Pending
- 2023-03-28 US US18/851,679 patent/US20250206760A1/en active Pending
- 2023-03-28 JP JP2024556197A patent/JP2025509995A/ja active Pending
- 2023-03-28 KR KR1020247034812A patent/KR20240167844A/ko active Pending
- 2023-03-28 EP EP23778158.8A patent/EP4501925A4/en active Pending
- 2023-03-28 WO PCT/CN2023/084265 patent/WO2023185793A1/zh not_active Ceased
- 2023-03-28 CA CA3253847A patent/CA3253847A1/en active Pending
- 2023-03-28 TW TW112111777A patent/TW202345816A/zh unknown
-
2024
- 2024-09-24 MX MX2024011705A patent/MX2024011705A/es unknown
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