JP2025505638A5 - - Google Patents

Info

Publication number
JP2025505638A5
JP2025505638A5 JP2024546369A JP2024546369A JP2025505638A5 JP 2025505638 A5 JP2025505638 A5 JP 2025505638A5 JP 2024546369 A JP2024546369 A JP 2024546369A JP 2024546369 A JP2024546369 A JP 2024546369A JP 2025505638 A5 JP2025505638 A5 JP 2025505638A5
Authority
JP
Japan
Prior art keywords
peg
alkyldiyl
succinimidyl
alkyl
heterocyclyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024546369A
Other languages
English (en)
Japanese (ja)
Other versions
JP2025505638A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2023/012576 external-priority patent/WO2023154307A1/en
Publication of JP2025505638A publication Critical patent/JP2025505638A/ja
Publication of JP2025505638A5 publication Critical patent/JP2025505638A5/ja
Pending legal-status Critical Current

Links

JP2024546369A 2022-02-09 2023-02-08 抗体コンジュゲート8-スルホニル-ベンザゼピン化合物及びそれらの使用 Pending JP2025505638A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202263308275P 2022-02-09 2022-02-09
US63/308,275 2022-02-09
PCT/US2023/012576 WO2023154307A1 (en) 2022-02-09 2023-02-08 Antibody-conjugated 8-sulfonyl-benzazepine compounds and their uses

Publications (2)

Publication Number Publication Date
JP2025505638A JP2025505638A (ja) 2025-02-28
JP2025505638A5 true JP2025505638A5 (https=) 2026-02-12

Family

ID=85778754

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024546369A Pending JP2025505638A (ja) 2022-02-09 2023-02-08 抗体コンジュゲート8-スルホニル-ベンザゼピン化合物及びそれらの使用

Country Status (10)

Country Link
US (1) US20250127914A1 (https=)
EP (1) EP4475893A1 (https=)
JP (1) JP2025505638A (https=)
KR (1) KR20240139086A (https=)
CN (1) CN118843481A (https=)
AU (1) AU2023216956A1 (https=)
IL (1) IL314755A (https=)
MX (1) MX2024009756A (https=)
TW (1) TW202339806A (https=)
WO (1) WO2023154307A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2026050214A1 (en) * 2024-08-27 2026-03-05 Bolt Biotherapeutics, Inc. Anti-claudin, tlr agonist immunoconjugates and uses thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6644792B2 (ja) * 2014-12-18 2020-02-12 エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト ベンザゼピンスルホンアミド化合物
CN108055842B (zh) * 2015-09-17 2021-06-29 豪夫迈·罗氏有限公司 亚磺酰基苯基或磺亚胺酰基苯基苯并氮杂䓬
CN109311854B (zh) * 2016-05-23 2021-08-10 豪夫迈·罗氏有限公司 具有仲酰胺官能团的苯并氮杂卓二甲酰胺化合物
AU2019337654A1 (en) * 2018-09-12 2021-04-08 Silverback Therapeutics, Inc. Substituted benzazepine compounds, conjugates, and uses thereof
US20200390899A1 (en) * 2019-06-13 2020-12-17 Bolt Biotherapeutics, Inc. Aminobenzazepine compounds, immunoconjugates, and uses thereof
US20220347310A1 (en) * 2019-09-30 2022-11-03 Bolt Biotherapeutics, Inc. Amide-linked, aminobenzazepine immunoconjugates, and uses thereof
JP7735291B2 (ja) * 2020-02-21 2025-09-08 エーアールエス ファーマシューティカルズ、インコーポレイテッド ネクチン-4抗体コンジュゲートおよびその使用
US20230293716A1 (en) * 2020-05-08 2023-09-21 Bolt Biotherapeutics, Inc. Elastase-substrate, peptide linker immunoconjugates, and uses thereof

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