JP2025503945A5 - - Google Patents
Info
- Publication number
- JP2025503945A5 JP2025503945A5 JP2024543955A JP2024543955A JP2025503945A5 JP 2025503945 A5 JP2025503945 A5 JP 2025503945A5 JP 2024543955 A JP2024543955 A JP 2024543955A JP 2024543955 A JP2024543955 A JP 2024543955A JP 2025503945 A5 JP2025503945 A5 JP 2025503945A5
- Authority
- JP
- Japan
- Prior art keywords
- substituted
- alkyl
- cycloalkyl
- heterocycloalkyl
- haloalkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202263304504P | 2022-01-28 | 2022-01-28 | |
| US63/304,504 | 2022-01-28 | ||
| US202263309442P | 2022-02-11 | 2022-02-11 | |
| US63/309,442 | 2022-02-11 | ||
| PCT/US2023/011752 WO2023147063A2 (en) | 2022-01-28 | 2023-01-27 | Compounds and methods for yap/tead modulation and indications therefor |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2025503945A JP2025503945A (ja) | 2025-02-06 |
| JP2025503945A5 true JP2025503945A5 (cg-RX-API-DMAC10.html) | 2026-01-27 |
Family
ID=87472579
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024543955A Withdrawn JP2025503945A (ja) | 2022-01-28 | 2023-01-27 | Ｙａｐ／ｔｅａｄ調節およびそれらの適応症のための化合物および方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20250129028A1 (cg-RX-API-DMAC10.html) |
| EP (1) | EP4469036A4 (cg-RX-API-DMAC10.html) |
| JP (1) | JP2025503945A (cg-RX-API-DMAC10.html) |
| AU (1) | AU2023211607A1 (cg-RX-API-DMAC10.html) |
| CA (1) | CA3248820A1 (cg-RX-API-DMAC10.html) |
| WO (1) | WO2023147063A2 (cg-RX-API-DMAC10.html) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN119968359A (zh) | 2022-09-29 | 2025-05-09 | 英矽智能科技知识产权有限公司 | Tead抑制剂及其使用方法 |
| AU2024212529A1 (en) * | 2023-01-27 | 2025-06-19 | Opna Bio SA | Compounds and methods for yap/tead modulation and indications therefor |
| WO2025209524A1 (en) * | 2024-04-03 | 2025-10-09 | Insilico Medicine Ip Limited | Crystalline tead inhibitor and uses thereof |
| WO2026096702A1 (en) * | 2024-10-31 | 2026-05-07 | The Trustees Of Indiana University | Autosomal dominant polycystic kidney disease therapy |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2006307939B2 (en) * | 2005-10-26 | 2012-03-29 | Merck Serono Sa | Sulfonamide derivatives and use thereof for the modulation of metalloproteinases |
| WO2012154760A1 (en) * | 2011-05-10 | 2012-11-15 | Gilead Sciences, Inc. | Fused heterocyclic compounds as sodium channel modulators |
| US10738026B2 (en) * | 2014-02-12 | 2020-08-11 | Purdue Pharma L.P. | Isoquinoline derivatives and use thereof |
| EP3322702B1 (en) * | 2015-07-14 | 2019-11-20 | Mission Therapeutics Limited | Cyanopyrrolidines as dub inhibitors for the treatment of cancer |
| JP2019501143A (ja) * | 2015-12-04 | 2019-01-17 | ヴィーブ ヘルスケア ユーケー リミテッド | テトラヒドロイソキノリン誘導体 |
| AU2020257207B2 (en) * | 2019-04-16 | 2026-06-04 | Vivace Therapeutics, Inc. | Bicyclic compounds |
| CN113801060B (zh) * | 2020-06-13 | 2025-06-27 | 苏州鹏旭医药科技有限公司 | 一种多取代异喹啉化合物的制备方法 |
| CN117956996A (zh) * | 2021-05-11 | 2024-04-30 | Opna 生物公司 | 用于yap/tead调节的化合物和方法及其适应证 |
-
2023
- 2023-01-27 AU AU2023211607A patent/AU2023211607A1/en active Pending
- 2023-01-27 CA CA3248820A patent/CA3248820A1/en active Pending
- 2023-01-27 EP EP23747655.1A patent/EP4469036A4/en active Pending
- 2023-01-27 JP JP2024543955A patent/JP2025503945A/ja not_active Withdrawn
- 2023-01-27 WO PCT/US2023/011752 patent/WO2023147063A2/en not_active Ceased
-
2024
- 2024-07-26 US US18/785,056 patent/US20250129028A1/en active Pending
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