JP2025503730A5 - - Google Patents

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Publication number
JP2025503730A5
JP2025503730A5 JP2024542279A JP2024542279A JP2025503730A5 JP 2025503730 A5 JP2025503730 A5 JP 2025503730A5 JP 2024542279 A JP2024542279 A JP 2024542279A JP 2024542279 A JP2024542279 A JP 2024542279A JP 2025503730 A5 JP2025503730 A5 JP 2025503730A5
Authority
JP
Japan
Prior art keywords
modified mrna
region
poly
polya
utr
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024542279A
Other languages
English (en)
Japanese (ja)
Other versions
JP2025503730A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2023/060852 external-priority patent/WO2023141474A1/en
Publication of JP2025503730A publication Critical patent/JP2025503730A/ja
Publication of JP2025503730A5 publication Critical patent/JP2025503730A5/ja
Priority to JP2025177566A priority Critical patent/JP2026016516A/ja
Pending legal-status Critical Current

Links

JP2024542279A 2022-01-18 2023-01-18 ポリテール化及びポリキャップ化ｍＲＮＡ並びにそれらの使用 Pending JP2025503730A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2025177566A JP2026016516A (ja) 2022-01-18 2025-10-22 ポリテール化及びポリキャップ化ｍＲＮＡ並びにそれらの使用

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202263300602P 2022-01-18 2022-01-18
US63/300,602 2022-01-18
PCT/US2023/060852 WO2023141474A1 (en) 2022-01-18 2023-01-18 Poly-tailed and poly-capped mrna and uses thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2025177566A Division JP2026016516A (ja) 2022-01-18 2025-10-22 ポリテール化及びポリキャップ化ｍＲＮＡ並びにそれらの使用

Publications (2)

Publication Number Publication Date
JP2025503730A JP2025503730A (ja) 2025-02-04
JP2025503730A5 true JP2025503730A5 (https=) 2025-09-01

Family

ID=85381073

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2024542279A Pending JP2025503730A (ja) 2022-01-18 2023-01-18 ポリテール化及びポリキャップ化ｍＲＮＡ並びにそれらの使用
JP2025177566A Pending JP2026016516A (ja) 2022-01-18 2025-10-22 ポリテール化及びポリキャップ化ｍＲＮＡ並びにそれらの使用

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2025177566A Pending JP2026016516A (ja) 2022-01-18 2025-10-22 ポリテール化及びポリキャップ化ｍＲＮＡ並びにそれらの使用

Country Status (8)

Country Link
US (1) US20240392311A1 (https=)
EP (2) EP4466074A1 (https=)
JP (2) JP2025503730A (https=)
KR (2) KR20260006688A (https=)
CN (2) CN121718542A (https=)
AU (2) AU2023209862A1 (https=)
CA (1) CA3248956A1 (https=)
WO (1) WO2023141474A1 (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2025519910A (ja) * 2022-06-24 2025-06-26 ザ・ブロード・インスティテュート・インコーポレイテッド キャップされた環状ｒｎａ分子を調製するための組成物及び方法
WO2025076085A1 (en) * 2023-10-02 2025-04-10 Convergence Bio, Inc. Multi-terminus polya polynucleotides
WO2025111430A1 (en) * 2023-11-21 2025-05-30 Prime Medicine, Inc. CHEMICAL MODIFICATIONS IN mRNA POLY(A) TAIL
WO2025147660A2 (en) * 2024-01-04 2025-07-10 Trilink Biotechnologies, Llc Modified rna for increasing protein expression
WO2025175176A1 (en) * 2024-02-14 2025-08-21 Modernatx, Inc. Synthetic nucleic acids and methods of using the same for improved polypeptide production
WO2025180432A1 (zh) * 2024-02-28 2025-09-04 图维生物医药科技(苏州)有限公司 一种用于rna加帽的酶及其反应体系
WO2025217126A1 (en) * 2024-04-09 2025-10-16 Convergence Bio, Inc. Polynucleotides, 3' chain terminating tails, ligation and uses thereof
WO2025217135A1 (en) * 2024-04-09 2025-10-16 Convergence Bio, Inc. Rna ligation methods and products

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MA53669A (fr) * 2018-09-20 2021-07-28 Modernatx Inc Compositions et procédés d'administration d'acides nucléiques
BR112021023411A2 (pt) 2019-05-22 2022-02-01 Massachusetts Inst Technology Composições e métodos de rna circular
JP2024518546A (ja) * 2021-05-12 2024-05-01 ザ ブロード インスティテュート，インコーポレーテッド 修飾されたｍＲＮＡ、修飾された非コードＲＮＡ、およびその使用

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