JP2021532745A5 - - Google Patents
Info
- Publication number
- JP2021532745A5 JP2021532745A5 JP2021504450A JP2021504450A JP2021532745A5 JP 2021532745 A5 JP2021532745 A5 JP 2021532745A5 JP 2021504450 A JP2021504450 A JP 2021504450A JP 2021504450 A JP2021504450 A JP 2021504450A JP 2021532745 A5 JP2021532745 A5 JP 2021532745A5
- Authority
- JP
- Japan
- Prior art keywords
- aptamer
- car
- binding
- target
- bridge
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024107323A JP2024133576A (ja) | 2018-07-26 | 2024-07-03 | アプタマーベースのｃａｒ ｔ－細胞スイッチ |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862703869P | 2018-07-26 | 2018-07-26 | |
| US62/703,869 | 2018-07-26 | ||
| US201962879401P | 2019-07-26 | 2019-07-26 | |
| US62/879,401 | 2019-07-26 | ||
| PCT/IB2019/000890 WO2020021338A2 (en) | 2018-07-26 | 2019-07-26 | Aptamer-based car t-cell switch |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024107323A Division JP2024133576A (ja) | 2018-07-26 | 2024-07-03 | アプタマーベースのｃａｒ ｔ－細胞スイッチ |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021532745A JP2021532745A (ja) | 2021-12-02 |
| JP2021532745A5 true JP2021532745A5 (https=) | 2022-08-03 |
| JP7642236B2 JP7642236B2 (ja) | 2025-03-10 |
Family
ID=68470556
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021504450A Active JP7642236B2 (ja) | 2018-07-26 | 2019-07-26 | アプタマーベースのｃａｒ ｔ－細胞スイッチ |
| JP2024107323A Pending JP2024133576A (ja) | 2018-07-26 | 2024-07-03 | アプタマーベースのｃａｒ ｔ－細胞スイッチ |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024107323A Pending JP2024133576A (ja) | 2018-07-26 | 2024-07-03 | アプタマーベースのｃａｒ ｔ－細胞スイッチ |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US12209243B2 (https=) |
| JP (2) | JP7642236B2 (https=) |
| KR (2) | KR102905569B1 (https=) |
| AU (1) | AU2019309328B2 (https=) |
| BR (1) | BR112021001475A2 (https=) |
| CA (1) | CA3106667A1 (https=) |
| MX (1) | MX2021001006A (https=) |
| WO (1) | WO2020021338A2 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102905569B1 (ko) * | 2018-07-26 | 2025-12-31 | 아라팅가 바이오 티엔피 | 압타머-기반 car t-세포 스위치 |
| US20220251562A1 (en) * | 2019-07-26 | 2022-08-11 | Ixaka France | Anti-CD3 Aptamers for Use in Cell Targeting and Labeling |
| WO2021156277A1 (en) * | 2020-02-04 | 2021-08-12 | Miltenyi Biotec B.V. & Co. KG | Immune cell expressing adapter chimeric antigen receptor for sensing soluble antigens |
| EP4705466A1 (en) * | 2023-04-26 | 2026-03-11 | University of Cincinnati | Surface bound multi-bond aptamer sensors |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5270163A (en) | 1990-06-11 | 1993-12-14 | University Research Corporation | Methods for identifying nucleic acid ligands |
| WO2010144295A1 (en) * | 2009-06-09 | 2010-12-16 | University Of Miami | Aptamer-targeted costimulatory ligand aptamer |
| WO2012076190A1 (en) | 2010-12-10 | 2012-06-14 | Merck Patent Gmbh | Bispecific aptamers mediating tumour cell lysis |
| EP2990416B1 (en) | 2014-08-29 | 2018-06-20 | GEMoaB Monoclonals GmbH | Universal chimeric antigen receptor expressing immune cells for targeting of diverse multiple antigens and method of manufacturing the same and use of the same for treatment of cancer, infections and autoimmune disorders |
| US10577610B2 (en) * | 2015-02-11 | 2020-03-03 | Deakin University | EpCAM aptamers and conjugates thereof |
| US11219635B2 (en) * | 2016-02-19 | 2022-01-11 | City Of Hope | Bi-specific aptamer |
| EP3567101A4 (en) * | 2017-01-05 | 2020-12-02 | Korea Research Institute of Bioscience and Biotechnology | NATURAL KILLER CELL EXPRESSING AN ANTI-COTININ CHEMERIC ANTIGEN RECEPTOR |
| KR102905569B1 (ko) * | 2018-07-26 | 2025-12-31 | 아라팅가 바이오 티엔피 | 압타머-기반 car t-세포 스위치 |
-
2019
- 2019-07-26 KR KR1020217004865A patent/KR102905569B1/ko active Active
- 2019-07-26 KR KR1020257043012A patent/KR20260011768A/ko active Pending
- 2019-07-26 BR BR112021001475-6A patent/BR112021001475A2/pt unknown
- 2019-07-26 US US17/262,532 patent/US12209243B2/en active Active
- 2019-07-26 AU AU2019309328A patent/AU2019309328B2/en active Active
- 2019-07-26 MX MX2021001006A patent/MX2021001006A/es unknown
- 2019-07-26 JP JP2021504450A patent/JP7642236B2/ja active Active
- 2019-07-26 WO PCT/IB2019/000890 patent/WO2020021338A2/en not_active Ceased
- 2019-07-26 CA CA3106667A patent/CA3106667A1/en active Pending
-
2024
- 2024-07-03 JP JP2024107323A patent/JP2024133576A/ja active Pending
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