JP2025503511A5 - - Google Patents

Info

Publication number
JP2025503511A5
JP2025503511A5 JP2024538652A JP2024538652A JP2025503511A5 JP 2025503511 A5 JP2025503511 A5 JP 2025503511A5 JP 2024538652 A JP2024538652 A JP 2024538652A JP 2024538652 A JP2024538652 A JP 2024538652A JP 2025503511 A5 JP2025503511 A5 JP 2025503511A5
Authority
JP
Japan
Prior art keywords
cancer
pharmaceutical product
product according
her2
amino acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024538652A
Other languages
English (en)
Japanese (ja)
Other versions
JP2025503511A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/IB2022/062797 external-priority patent/WO2023126822A1/en
Publication of JP2025503511A publication Critical patent/JP2025503511A/ja
Publication of JP2025503511A5 publication Critical patent/JP2025503511A5/ja
Pending legal-status Critical Current

Links

JP2024538652A 2021-12-28 2022-12-27 抗体-薬物コンジュゲート及びrasg12c阻害剤の組み合わせ Pending JP2025503511A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163294367P 2021-12-28 2021-12-28
US63/294,367 2021-12-28
PCT/IB2022/062797 WO2023126822A1 (en) 2021-12-28 2022-12-27 Combination of antibody-drug conjugate and rasg12c inhibitor

Publications (2)

Publication Number Publication Date
JP2025503511A JP2025503511A (ja) 2025-02-04
JP2025503511A5 true JP2025503511A5 (enExample) 2026-01-05

Family

ID=84943594

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024538652A Pending JP2025503511A (ja) 2021-12-28 2022-12-27 抗体-薬物コンジュゲート及びrasg12c阻害剤の組み合わせ

Country Status (6)

Country Link
US (1) US20250161305A1 (enExample)
EP (1) EP4456899A1 (enExample)
JP (1) JP2025503511A (enExample)
CN (1) CN118434422A (enExample)
TW (1) TW202333800A (enExample)
WO (1) WO2023126822A1 (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2026124488A1 (zh) * 2024-12-10 2026-06-18 正大天晴药业集团股份有限公司 抗her2抗体药物偶联物或其联用药物治疗非小细胞肺癌的用途

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL162181A (en) 1988-12-28 2006-04-10 Pdl Biopharma Inc A method of producing humanized immunoglubulin, and polynucleotides encoding the same
EP0590058B1 (en) 1991-06-14 2003-11-26 Genentech, Inc. HUMANIZED Heregulin ANTIBODy
EP0699754B2 (en) 1994-08-12 2009-08-12 The University of Utah Research Foundation Method for diagnosing a predisposition for breast and ovarian cancer
DE69521002T3 (de) 1994-08-12 2010-02-25 The University Of Utah Research Foundation, Salt Lake City Mutationen des mit 17q verbundenen Ovarial- und Brustkrebs Empfindlichkeitsgens
JP4334141B2 (ja) 1998-04-20 2009-09-30 グリカート バイオテクノロジー アクチェンゲゼルシャフト 抗体依存性細胞傷害性を改善するための抗体のグリコシル化操作
EP2275540B1 (en) 1999-04-09 2016-03-23 Kyowa Hakko Kirin Co., Ltd. Method for controlling the activity of immunologically functional molecule
AR024464A1 (es) 1999-06-25 2002-10-02 Genentech Inc Anticuerpos anti-erbb2 humanizados.
CN103333860B (zh) 2000-10-06 2015-07-08 协和发酵麒麟株式会社 产生抗体组合物的细胞
CA2647632C (en) 2006-03-27 2017-06-27 University Of Maryland Biotechnology Institute Glycoprotein synthesis and remodeling by enzymatic transglycosylation
JP6282232B2 (ja) 2012-02-10 2018-02-21 ユニバーシティー オブ メリーランド,ボルティモア 抗体及びそのFcフラグメントの酵素化学的糖鎖改変
US10195288B2 (en) 2012-10-11 2019-02-05 Daiichi Sankyo Company, Limited Antibody-drug conjugate
SG10201902571VA (en) 2013-12-25 2019-04-29 Daiichi Sankyo Co Ltd Anti-trop2 antibody-drug conjugate
SG11201603960XA (en) 2014-01-31 2016-07-28 Daiichi Sankyo Co Ltd Anti-her2 antibody-drug conjugate
TWI871999B (zh) 2014-04-10 2025-02-01 日商第一三共股份有限公司 抗her3抗體-藥物結合物
CA2990572C (en) 2015-06-29 2022-07-26 Daiichi Sankyo Company, Limited Method for selectively manufacturing antibody-drug conjugate
TWI926682B (zh) 2017-05-15 2026-05-21 日商第一三共股份有限公司 抗體-藥物結合物之製造方法
EP3677589B1 (en) 2017-08-31 2025-11-26 Daiichi Sankyo Company, Limited Improved method for producing antibody-drug conjugate
CA3082579A1 (en) 2017-11-15 2019-05-23 Mirati Therapeutics, Inc. Kras g12c inhibitors
TW202012415A (zh) 2018-05-08 2020-04-01 瑞典商阿斯特捷利康公司 化學化合物
ES3010507T3 (en) 2019-03-05 2025-04-03 Astrazeneca Ab Fused tricyclic compounds useful as anticancer agents
CR20220258A (es) 2019-12-11 2022-07-03 Lilly Co Eli Inhibidores de kras g12c
CN116034106B (zh) 2020-06-02 2025-11-04 勃林格殷格翰国际有限公司 用于治疗癌症的环状2-氨基-3-氰基噻吩及衍生物

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