JP2025503480A5 - - Google Patents

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Publication number
JP2025503480A5
JP2025503480A5 JP2024537849A JP2024537849A JP2025503480A5 JP 2025503480 A5 JP2025503480 A5 JP 2025503480A5 JP 2024537849 A JP2024537849 A JP 2024537849A JP 2024537849 A JP2024537849 A JP 2024537849A JP 2025503480 A5 JP2025503480 A5 JP 2025503480A5
Authority
JP
Japan
Prior art keywords
chain variable
variable region
antigen
heavy chain
immunoglobulin heavy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024537849A
Other languages
English (en)
Japanese (ja)
Other versions
JP2025503480A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2022/082131 external-priority patent/WO2023122659A2/en
Publication of JP2025503480A publication Critical patent/JP2025503480A/ja
Publication of JP2025503480A5 publication Critical patent/JP2025503480A5/ja
Pending legal-status Critical Current

Links

JP2024537849A 2021-12-21 2022-12-21 条件付きで活性化される抗原結合ポリペプチド複合体及びその使用方法 Pending JP2025503480A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163292382P 2021-12-21 2021-12-21
US63/292,382 2021-12-21
PCT/US2022/082131 WO2023122659A2 (en) 2021-12-21 2022-12-21 Conditionally activated antigen binding polypeptide complexes and methods of use thereof

Publications (2)

Publication Number Publication Date
JP2025503480A JP2025503480A (ja) 2025-02-04
JP2025503480A5 true JP2025503480A5 (https=) 2026-01-05

Family

ID=86903785

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024537849A Pending JP2025503480A (ja) 2021-12-21 2022-12-21 条件付きで活性化される抗原結合ポリペプチド複合体及びその使用方法

Country Status (13)

Country Link
US (1) US20240059798A1 (https=)
EP (1) EP4452317A4 (https=)
JP (1) JP2025503480A (https=)
KR (1) KR20240134257A (https=)
CN (4) CN118251411A (https=)
AR (1) AR128060A1 (https=)
AU (1) AU2022420594A1 (https=)
CA (1) CA3240079A1 (https=)
CL (1) CL2024001850A1 (https=)
IL (1) IL313770A (https=)
MX (1) MX2024007393A (https=)
TW (1) TW202334204A (https=)
WO (1) WO2023122659A2 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111201030B (zh) 2017-07-25 2024-11-01 真和制药有限公司 通过阻断tim-3和其配体的相互作用治疗癌症
WO2020160156A2 (en) 2019-01-30 2020-08-06 Immutics, Inc. Anti-gal3 antibodies and uses thereof
EP4157338A4 (en) 2020-05-26 2024-11-13 TrueBinding, Inc. METHOD FOR TREATING INFLAMMATORY DISEASES BY GALECTIN-3 BLOCKING
WO2025249301A1 (ja) * 2024-05-27 2025-12-04 国立大学法人東京農工大学 多重特異性抗体、がん増殖抑制剤、ポリヌクレオチド及び発現ベクター
CN121248779A (zh) * 2024-06-25 2026-01-02 冕屹立生物技术(上海)有限公司 靶向人cd3分子的抗体及其应用

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI743461B (zh) * 2011-03-28 2021-10-21 法商賽諾菲公司 具有交叉結合區定向之雙重可變區類抗體結合蛋白
US9458244B2 (en) * 2012-12-28 2016-10-04 Abbvie Inc. Single chain multivalent binding protein compositions and methods
RS62437B1 (sr) * 2015-10-25 2021-11-30 Sanofi Sa Trispecifični i/ili trivalentni vezujući proteini za prevenciju ili lečenje hiv infekcije
CA3020633A1 (en) * 2016-04-13 2017-10-19 Sanofi Trispecific and/or trivalent binding proteins
WO2018075564A1 (en) * 2016-10-17 2018-04-26 University Of Maryland, College Park Multispecific antibodies targeting human immunodeficiency virus and methods of using the same
BR112020016944A2 (pt) * 2018-02-20 2020-12-15 Dragonfly Therapeutics, Inc. Domínios variáveis de anticorpo que alvejam cd33 e uso dos mesmos
MX2021000307A (es) * 2018-07-11 2021-09-08 Momenta Pharmaceuticals Inc Composiciones y métodos relacionados con constructos de dominio de unión a antígeno-fc dirigidos a cd38 diseñados por ingeniería genética.
US12365722B2 (en) * 2018-10-19 2025-07-22 University Of Maryland, College Park Multispecific antibodies targeting multiple epitopes on the HIV-1 envelope
AU2019372673A1 (en) * 2018-11-01 2021-05-27 Gracell Biotechnologies (Shanghai) Co., Ltd. Compositions and methods for T cell engineering
US11613576B2 (en) * 2019-04-09 2023-03-28 Sanofi Trispecific binding proteins, methods, and uses thereof
TW202104274A (zh) * 2019-04-09 2021-02-01 法商賽諾菲公司 用於治療hiv感染之三特異性及/或三價結合蛋白
TW202330594A (zh) * 2021-09-29 2023-08-01 美商莫德斯醫療公司 抗原結合多肽、抗原結合多肽複合物及其使用方法
IL313617A (en) * 2021-12-17 2024-08-01 Modex Therapeutics Inc Antigen-binding polypeptide complexes containing extracellular regions of TNFSF ligands

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