JP2025501618A5 - - Google Patents
Info
- Publication number
- JP2025501618A5 JP2025501618A5 JP2024538334A JP2024538334A JP2025501618A5 JP 2025501618 A5 JP2025501618 A5 JP 2025501618A5 JP 2024538334 A JP2024538334 A JP 2024538334A JP 2024538334 A JP2024538334 A JP 2024538334A JP 2025501618 A5 JP2025501618 A5 JP 2025501618A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- membered
- substituted
- unsubstituted
- groups
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202111593577.4 | 2021-12-23 | ||
| CN202111593577 | 2021-12-23 | ||
| CN202211580672 | 2022-12-06 | ||
| CN202211580672.5 | 2022-12-06 | ||
| PCT/CN2022/141282 WO2023116866A1 (zh) | 2021-12-23 | 2022-12-23 | 一种五元并六元化合物、制备方法、药物组合物和应用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2025501618A JP2025501618A (ja) | 2025-01-22 |
| JP2025501618A5 true JP2025501618A5 (https=) | 2025-03-03 |
| JP7746587B2 JP7746587B2 (ja) | 2025-09-30 |
Family
ID=86901357
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024538334A Active JP7746587B2 (ja) | 2021-12-23 | 2022-12-23 | ５員縮合６員化合物、製造方法、医薬組成物、及び応用 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US12195479B2 (https=) |
| EP (1) | EP4434981A4 (https=) |
| JP (1) | JP7746587B2 (https=) |
| CN (2) | CN117177965B (https=) |
| TW (1) | TWI890016B (https=) |
| WO (1) | WO2023116866A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2024133560A1 (en) * | 2022-12-21 | 2024-06-27 | Dark Blue Therapeutics Ltd | Imidazo[1,2-a]pyridine and imidazo[1,2-a]pyrazine derivatives as mllt1 and mllt3 inhibitors |
| WO2024260404A1 (zh) * | 2023-06-21 | 2024-12-26 | 杭州多域生物技术有限公司 | 一种五元并六元化合物的晶型、盐型、制备方法、药物组合物和应用 |
| CN120665085A (zh) * | 2023-07-11 | 2025-09-19 | 四川轻化工大学 | 鼠尾草酚衍生物及其在治疗肿瘤恶病质药物中的应用 |
| CN119119080A (zh) * | 2024-09-06 | 2024-12-13 | 上海信诺维生物医药有限公司 | 一种irak4的蛋白降解剂 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5849922A (en) * | 1996-05-31 | 1998-12-15 | Eli Lilly And Company | Preparation of substituted alkenoic acids |
| EP3092226B1 (en) * | 2014-01-10 | 2019-03-13 | Aurigene Discovery Technologies Limited | Indazole compounds as irak4 inhibitors |
| LT3466955T (lt) * | 2014-01-13 | 2021-02-25 | Aurigene Discovery Technologies Limited | Oksazol[4,5-b]piridino ir tiazol[4,5-b]piridino darinių, kaip irak4 inhibitorių, skirtų vėžio gydymui, gamybos būdas |
| JP2018524372A (ja) * | 2015-07-15 | 2018-08-30 | アウリジーン ディスカバリー テクノロジーズ リミテッド | Ｉｒａｋ−４阻害剤としてのインダゾール及びアザインダゾール化合物 |
| CN108024971A (zh) * | 2015-07-15 | 2018-05-11 | 奥列基因发现技术有限公司 | 作为irak-4抑制剂的取代的氮杂化合物 |
| DK3331879T3 (da) * | 2015-08-04 | 2020-08-10 | Rigel Pharmaceuticals Inc | Benzazolforbindelser og fremgangsmåder til fremstilling og anvendelse af forbindelserne |
| EP3600270B1 (en) * | 2017-03-31 | 2023-06-14 | Aurigene Oncology Limited | Compounds and compositions for treating hematological disorders |
| HUE067356T2 (hu) | 2017-10-31 | 2024-10-28 | Curis Inc | IRAK4 inhibitor és BCL-2 inhibitor kombinációban, rák kezelésére való felhasználásra |
| DE102019213869A1 (de) | 2018-09-20 | 2020-03-26 | Carl Zeiss Meditec Ag | Erzeugung von Schnitten im Inneren des Auges |
| GB201904373D0 (en) * | 2019-03-29 | 2019-05-15 | Galapagos Nv | Novel compounds and pharamaceutical compositions thereof for the treatment of inflammatory disorders |
| PH12022500002A1 (en) * | 2019-06-28 | 2023-04-03 | Kymera Therapeutics Inc | Irak degraders and uses thereof |
| CN113278017B (zh) * | 2021-05-27 | 2023-03-28 | 上海应用技术大学 | 取代吲唑类化合物、制备方法、应用和包含其的组合物 |
-
2022
- 2022-12-23 EP EP22910177.9A patent/EP4434981A4/en active Pending
- 2022-12-23 WO PCT/CN2022/141282 patent/WO2023116866A1/zh not_active Ceased
- 2022-12-23 CN CN202280030429.8A patent/CN117177965B/zh active Active
- 2022-12-23 CN CN202410575992.4A patent/CN118530221A/zh active Pending
- 2022-12-23 JP JP2024538334A patent/JP7746587B2/ja active Active
- 2022-12-23 TW TW111149760A patent/TWI890016B/zh active
-
2023
- 2023-12-19 US US18/544,546 patent/US12195479B2/en active Active
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